Effect of Bacillus subtilis JZXJ-7, a Strain Isolated from Shrimp Paste, on Colonic Function and Microbial Community in Mice Infected with Vibrio parahaemolyticus by ZHOU Kui, WANG Rundong, GONG Mengxue, MOU Jingyuan, DENG Yijia, LI Xuepeng, ZHANG Yuhao, LI Jianrong

“…In summary, JZXJ-7 can effectively alleviate colonic pathological damage in Vp infected mice and maintain intestinal functions, and the underlying mechanism may be related to its regulatory effect on the intestinal microbiota.…”
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Screening of Anti-Inflammatory Components of Qin Jin Hua Tan Tang by a Multivariate Statistical Analysis Approach for Spectrum-Effect Relationships by Feipeng Duan, Yisheng Li, Meizhen Zhao, Tianyong Hu, Xinquan Pan, Yue Feng, Fang Ma, Shuqi Qiu, Yiqing Zheng

“…The potential anti-inflammatory ingredients obtained from the screening (multivariate statistical analysis) will be validated for their anti-inflammatory effects and mechanisms utilizing a lipopolysaccharide-induced macrophage inflammation model. …”
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Sex life dissatisfaction contribute to intention toward infidelity among Malaysians: relationship satisfaction as a mediator by Soon Aun Tan, Siew Mun Ang, Pit Wan Pung, Xi Yao Teoh, Seow Ling Ooh

“…Nonetheless, the underlying mechanism of the association between sex life satisfaction and intention toward infidelity is unexplored in the Malaysian context. …”
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Quantitative Complexity Theory Used in the Prediction of Head-Up Tilt Testing Outcome by Paweł Krzesiński, Jacek Marczyk, Bartosz Wolszczak, Grzegorz Gielerak

“…Head-up tilt testing (HUTT), a well-established tool in the diagnosis of vasovagal syncope, is time-consuming, and every provoked vasovagal reaction may result in consolidating the reflex mechanism. Therefore, identification of parameters that could shorten the duration of HUTT and prevent fainting is desirable. …”
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Disulfidptosis-related gene SLC3A2: a novel prognostic biomarker in nasopharyngeal carcinoma and head and neck squamous cell carcinoma by Xinyi Zhang, Yiqi Lin, Liang Shi, Aixia Zhai, Chao Wu, Qian-Ying Zhu

“…In vitro, SLC3A2's influence on cell proliferation, migration, and invasion was evaluated through CCK8, wound healing, colony formation, transwell assays, and cell cycle analysis.ResultsIn this study, we identified the high expression of SLC3A2 in NPC and head and neck squamous cell carcinoma (HNSC) and analyzed its potential mechanism and correlation with patient prognosis. Furthermore, a negative relationship was found between the expression level of SLC3A2 and the extent of immune cell infiltration and immune checkpoint. …”
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Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1 by Xiaowen Hu, Mengsiyu Li, Chunxue Zhang, Shuguang Pang

“…Herein, we designed experiments to investigate the effects and mechanisms of metformin on SULT2A1 expression in vitro. …”
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Optimising transitions of care for acute kidney injury survivors: protocol for a mixed-methods study of nephrologist and primary care provider recommendations by Rozalina Grubina McCoy, Kianoush B Kashani, Joan M Griffin, Heather Personett May, Abby K Krauter, Dawn M Finnie, Erin F Barreto

“…Building capacity across the healthcare spectrum by engaging a broad network of multidisciplinary providers to facilitate optimal follow-up care represents an important mechanism to address this existing care gap. Key participants include nephrologists and primary care providers and in-depth study of each specialty’s approach to post-AKI care is essential to optimise care processes and healthcare delivery for AKI survivors.Methods and analysis This explanatory sequential mixed-methods study uses survey and interview methodology to assess nephrologist and primary care provider recommendations for post-AKI care, including KAMPS (kidney function assessment, awareness and education, medication review, blood pressure monitoring and sick day education) elements of follow-up, the role of multispecialty collaboration, and views on care process-specific and patient-specific factors influencing healthcare delivery. …”
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Unveiling the role of melatonin‐related gene CSNK1D in osteoclastogenesis and its implications for osteoporosis treatment by Jiewen Zhang, Shaobo Wu, Fangze Xing, Ning Kong, Yiwei Zhao, Xudong Duan, Yiyang Li, Kunzheng Wang, Run Tian, Pei Yang

“…Melatonin is a circadian regulator that affects bone metabolism, but its molecular mechanism has not been studied in detail. This study aimed to identify the relationship between melatonin‐related genes and OP through bioinformatics methods and to verify it experimentally.We analysed microarray data from the GSE35959 dataset, identifying differentially expressed genes in OP patients. …”
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Metabolic and hematological disruptions induced by Diphenyl Diselenide in male wistar rats by Joseph A. Olagunju, Gabriel O. Ajayi, Babatunde A. Murtala, Adejuwan A. Adeneye

“…The resultant increased gluconeogenesis and hepatic glycogen storage could be a detoxification mechanism whereby excess lactate due to increased glycolysis is converted to a non-toxic and neutral glucose to maintain pH balance in order to preserve the animals against DPDS toxicity.…”
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Mitochondrial genome insights into the phylogenetics and biogeographic evolution of snow trout (Cyprinidae, Schizothorax) in the Tien Shan Mountains by Akbarjon Rozimov, Yufan Wang, Min Wang, Ming Zou, Jobir Sobirov, Erkin Karimov, Bakhtiyor Kholmatov, Jörg Freyhof, Sirojiddin Namozov, Chongnv Wang, Xinxin Li, Baocheng Guo

“…Our findings not only clarify the evolutionary histories of snow trout in the Tien Shan Mountains but also advance our understanding of the mechanisms shaping the rich biodiversity.…”
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Synthesis and crystal structure of piperidinyl propanenitrile towards the preparation of piperidine based bioactive films for drug delivery applications by Reham A. Mohamed-Ezzat, Mohamed S. Hasanin, Benson M. Kariuki, Sawsan Dacrory

“…The films showed smooth, homogenous surfaces and good mechanical properties. The results revealed that the films are bioactive, as indicated by promising antimicrobial potency against P. aeruginosa, S. aureus, E. coli, B. subtilis, and C. albicans, with high potency as well as moderate activity against A. niger. …”
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Mutual Coupling Reduction between Two Closely Spaced Antennas with a General PMC Symmetry Plane for Mobile Terminals by Yijiao Fang, Jiangwei Zhong, Yao Nie, Maosheng Fu

“…To validate the utility of this approach, we analyze the current/field distribution of this structure and the mode superposition mechanism in the present paper. The results show that, with a close center-to-center distance of 5 mm, the isolation between the arrays is improved from −5 dB to −20 dB at around 2.4 GHz. …”
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Effects of Concentration of Pore Solution on Stability of Ion-Absorbed Rare Earth Ore Aggregate by Jie Wang, Guanshi Wang, Bengen Hong

“…In this study, influences of the concentration of ammonium sulfate ((NH4)2SO4) solution on the interaction forces between ore particles were calculated. On this basis, the mechanism by which (NH4)2SO4 solution concentration influences the stability of ore aggregate was analyzed. …”
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Blimp-1 orchestrates macrophage polarization and metabolic homeostasis via purine biosynthesis in sepsis by Wenjuan Peng, Qiushi Qin, Rui Li, Yujia Liu, Lan Li, Yue Zhang, Liuluan Zhu

“…Our findings unveil a novel mechanism by which Blimp-1 modulates macrophage polarization through metabolic regulation, presenting potential therapeutic targets for sepsis. …”
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Characterization of Novel Nonobese Type 2 Diabetes Rat Model with Enlarged Kidneys by Ayaka Domon, Kentaro Katayama, Yuki Tochigi, Hiroetsu Suzuki

“…Taken together, these findings indicate that the affected males of the DEK strain are a novel nonobese type 2 diabetes rat model useful for studying the mechanisms underlying β cell loss and identifying genetic factors protective against DN.…”
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Profile of Endothelin-1, Nitric Oxide, and Prostacyclin Levels in Pulmonary Arterial Hypertension Related to Uncorrected Atrial Septal Defect: Results from a Single Center Study in... by Lucia Kris Dinarti, Anggoro Budi Hartopo, Dyah Wulan Anggrahini, Ahmad Hamim Sadewa, Budi Yuli Setianto, Abdus Samik Wahab

“…Pulmonary arterial hypertension (PAH) pathomechanism involves an increased plasma level of endothelin-1 and a reduced plasma level of prostacyclin and nitric oxide. Whether similar mechanisms prevail in PAH associated with atrial septal defect (ASD) is unclear. …”
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Comparing personality traits of healthcare workers with and without long COVID: Cross‐sectional study by Keiko Sakai, Seiichiro Tarutani, Takehiko Okamura, Hiroshi Yoneda, Tatsuhito Kawasaki, Masatoshi Takeda

“…Abstract Aim Pathological mechanisms of “long COVID” after recovery from the main symptoms of COVID‐19 are unclear. …”
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Prognostic role of aetiological agent vs. clinical pattern in candidates to lead extraction for cardiac implantable electronic device infections by Giulia Massaro, Renato Pascale, Mauro Biffi, Cristian Martignani, Matteo Ziacchi, Andrea Simeone, Raimondo Pittorru, Manuel De Lazzari, Federico Migliore, Igor Diemberger

“…This study supports the hypothesis that the infectious process may occur through different mechanisms associated with different infection patterns, and high-risk patients should be considered for specific and aggressive approaches.…”
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The relationship between career calling and presenteeism: the role of workaholism and self-compassion by Zhaobiao Zong, Feifei Sun, Haichao Sun, Shaoqing Su, Baojian Wei

“…Finally, the estimated indirect effect and moderated mediation coefficients were calculated at both high and low values of the moderating variable to assess the moderated mediation hypothesis.Results Our research reveals the underlying mechanism of workaholism and the mitigative effects of self-compassion in the career calling and presenteeism linkage. …”
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Development and performance evaluation of a modified Africa Bush Mango (<i>Irvingia gabomensis</i>) cracker by R.A. Busari, T.D. Akpenpuun, M.O. Iyanda

“…The cracker consists of a frame, cracking table, slider–crank mechanism, hopper, feed chute, slot, cracking unit electric motor and reduction gear. …”
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