An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET Gene by Fayeza Sadia Laskar, Md. Nazmul Islam Bappy, Md. Sowrov Hossain, Zenifer Alam, Dilruba Afrin, Sudeb Saha, Kazi Md. Ali Zinnah

“…It is found on the human chromosome number 7 and regulates the diverse cellular mechanisms of the human body. The impact of mutations occurring in the MET gene is demonstrated by their detrimental effects on normal cellular functions. …”
Get full text

Gene Editing in Pluripotent Stem Cells and Their Derived Organoids by Hang Zhou, Yun Wang, Li-Ping Liu, Yu-Mei Li, Yun-Wen Zheng

“…Gene editing in PSCs creates visualized in vitro models, providing opportunities for examining mechanisms of known and unknown mutations and offering new possibilities for the treatment of cancer, genetic diseases, and other serious or refractory disorders. …”
Get full text

Prevalence, Risk Factors and Outcomes Associated with Acute Kidney Injury in Patients Hospitalized for COVID-19: A Comparative Study between Diabetic and Nondiabetic Patients by Shayesteh Khalili, Tahereh Sabaghian, Meghdad Sedaghat, Zahra Soroureddin, Elham Askari, Neda Khalili

“…Multivariate analysis showed that invasive mechanical ventilation, proteinuria, HBA1c level, history of cardiovascular disease, and use of statins were independent risk factors for AKI development in patients with diabetes. …”
Get full text

Investigation of possibilities for high heavy metal content sludges utilization by incorporating them in concrete products by Simeonova A., Petkov A., Delchev N., Balgaranova J.

“…These molded concrete samples were characterized by their density, water absorption, and mechanical strength for defined standard periods of time. …”
Get full text

Effort-reward imbalance and health outcomes in emergency nurses: the mediating role of work–family conflict and intrinsic effort by Le Tong, Le Tong, Ling Zhu, Ling Zhu, Hao Zhang, Hao Zhang, Luying Zhong, Luying Zhong, Dongmei Diao, Dongmei Diao, Xiaoli Chen, Xiaoli Chen, Jianna Zhang, Jianna Zhang

“…BackgroundEmergency nurses experience high stress, but the mechanisms linking effort-reward imbalance to health outcomes are unclear. …”
Get full text

Single nucleotide polymorphism and expression of genes for immune competent cell proliferation and differentiation in radiation-exposed individuals by E. A. Blinova, V. S. Nikiforov, M. A. Yanishevskaya, A. A. Akleyev

“…It is known that ionizing radiation influences the expression of the genes that play a key role in the mechanisms of maintaining the stability of cellular homeostasis. …”
Get full text

A green route of antibacterial films production from shrimp (Penaeus monodon) shell waste biomass derived chitosan: Physicochemical, thermomechanical, morphological and antimicrobi... by Md. Mahmudur Rahman, Mohd. Maniruzzaman, Ripon Kumar Saha

“…Also exhibited a higher mechanical tensile strength (nearly 120.27 ± 0.091 N/mm2), elongation properties (around 43.98 ± 0.098 %), and a high antimicrobial activity. …”
Get full text

Les femmes américaines et la guerre du Vietnam : mise en place et utilisation d’un processus de mimétisme by Alexandra Boudet-Brugal

“…In doing so, I intend to examine whether the use of this mechanism reinforces the traditional representations of men and women in war: Does it allow a re-writing of these excluded female voices, while putting forward the specificities of women’s experiences in war? …”
Get full text

Inflammatory Markers in Rheumatoid Patients and Cardiac Function: Insights from an Iranian University Hospital by Fatemeh Omidi, Parisa Delkash

“…Further research is warranted to elucidate this association's underlying mechanisms and clinical implications.…”
Get full text

RNA interference of Aspergillus flavus in response to Aspergillus flavus partitivirus 1 infection by Yinhui Jiang, Yinhui Jiang, Xiang Liu, Xiang Liu, Xun Tian, Xun Tian, Jianhong Zhou, Jianhong Zhou, Qinrong Wang, Qinrong Wang, Bi Wang, Bi Wang, Wenfeng Yu, Wenfeng Yu, Yanping Jiang, Tom Hsiang, Xiaolan Qi, Xiaolan Qi

“…RNA interference (RNAi) is one of the important defense responses against viral infection, but its mechanism and impact remain unclear in mycovirus infections. …”
Get full text

Continuous cropping of Patchouli alters soil physiochemical properties and rhizosphere microecology revealed by metagenomic sequencing by Guangtao Gu, Muhammad Zeeshan Ul Haq, Xue Sun, Jingru Zhou, Ya Liu, Jing Yu, Dongmei Yang, Huageng Yang, Yougen Wu

“…In summary, this study showed the dynamic changes of soil factors and rhizosphere microorganisms during CC, providing a theoretical basis for understanding the formation mechanism and prevention of CC obstacles and contributing to the formulation of scientific soil management and fertilization strategies.…”
Get full text

The critical role of MLKL in hemorrhagic stroke and the therapeutic potential of its associated protein network by Yi Wang, Yi Wang, Moran Xu, Xiaoli Zuo, Sheng Wang, Yong Yu, Zhaobing Gao, Zhaobing Gao, Jingbo Qie, Ye Jiang, Fang Huang, Bingqing Xia, Bingqing Xia

“…Studies identified MLKL is a promoting factor in this process, suggesting its potential as a therapeutic target to mitigate posthemorrhagic stroke damage. However, the mechanisms by which MLKL functions in the process of intracerebral hemorrhage (ICH)-induced damage remain unclear.MethodsHere, we explored the correlation between MLKL and pathological damage in ICH patients through histopathological staining and RT-qPCR. …”
Get full text

Modification of Chitosan/PEG4000 dispersed with Lithium Triflate (LiCF\(_3\)SO\(_3\)) as a solid polymer electrolyte for the secondary battery by Kartika Sari, Arifin Nur Muhammad Haryadi, Nur Khusaenah, Sudaryanto, Evi Yulianti, Agung Bambang Setio Utomo

“…Solid-based electrolytes can be a good choice since they excel in the safety and stability of mechanical and electrical properties; however, they still have the disadvantage of low conductivity values (~10-4 - 10-6 S/cm), thus requiring modification. …”
Get full text

APBIO: bioactive profiling of air pollutants through inferred bioactivity signatures and prediction of novel target interactions by Eva Viesi, Ugo Perricone, Patrick Aloy, Rosalba Giugno

“…The proposed chemogenomic methodology enables the prediction of novel CTIs for known or similar compounds and targets through well-established and efficient ML models, deepening our insight into the molecular interactions and mechanisms that may have a deleterious impact on human biological systems.…”
Get full text

Determination of Appropriate Thresholding Method in Segmentation Stage in Detecting Breast Cancer Cells by Adem Polat, Cihat Ediz Akbaba

“…It is an electronic, mechan-ical, and software-based device capable of 3D imaging of tumoroids up to 1 cm in diameter in size. …”
Get full text

Oral Inflammation and Human Papilloma Virus Association among Hispanics by Maira A. Castañeda-Avila, Cynthia M. Pérez, José Vivaldi, Elba C. Díaz-Toro, Jeslie M. Ramos-Cartagena, Oelisoa M. Andriankaja, Ana P. Ortiz

“…Future studies need to further investigate the underlying mechanisms.…”
Get full text

Fast and Selective Adsorption of Au (III) from the Waste Printed Circuit Boards Using a Low-Cost Adsorbent: Optimization by Central Composite Design Based on Response Surface Metho... by Farideh Zandi-Darehgharibi, Hedayat Haddadi, Arash Asfaram

“…The thermodynamic study (∆S° > 0, ∆H° > 0, and ∆G° < 0) revealed that Au (III) adsorption via GA was a facile, endothermic, and spontaneous process. The adsorption mechanism could be an electrostatic interaction and reductive adsorption. …”
Get full text

Isolation and identification of novel casein-derived bioactive peptides and potential functions in fermented casein with Lactobacillus helveticus by Mengzhu Fan, Tingting Guo, Wanru Li, Jing Chen, Fushuo Li, Chao Wang, Yi Shi, David Xi-an Li, Shaohui Zhang

“…Intracellular peptides are much larger in quantity and more complex in composition than extracellular peptides, between which the correlation reveals proteolytic and metabolic mechanisms.In addition, totally 241 different peptide sequences were identified by Nano LC–MS/MS from casein (212) and Lactobacillus helveticus proteins (29). …”
Get full text

Pharmacological Modulation of the Unfolded Protein Response as a Therapeutic Approach in Cutaneous T-Cell Lymphoma by Nadia St. Thomas, Benjamin N. Christopher, Leticia Reyes, Reeder M. Robinson, Lena Golick, Xiaoyi Zhu, Eli Chapman, Nathan G. Dolloff

“…Conditioned media (CM) from CTCL were immunosuppressive to normal T cells through an IL-10-dependent mechanism. This immunosuppression could be reversed by JG-023, other HSP70 inhibitors, Btz, and combinations of these UPR-targeted drugs. …”
Get full text

Ion beam induced secondary electron tomography of acrylonitrile-styrene-acrylate/polycarbonate polymer blends for fused filament fabrication and injection moulding by J. Hernández-Saz, D. Moreno-Sanchez, L. M. Valencia, Y. Gómez, S. I. Molina, M. Herrera

“…The reasons for the different morphologies obtained in the studied blends and possible effects in their mechanical properties are discussed.…”
Get full text