Treatment of inoperable pancreatic adenocarcinoma with focused ultrasound and microbubbles in patients receiving chemotherapy by Margrete Haram, Rune Hansen, Ola Finneng Myhre, Stian Solberg, Naseh Amini, Bjørn Atle Angelsen, Catharina de Lange Davies, Eva Hofsli

“…After chemotherapy (FOLFIRINOX or nab-paclitaxel-gemcitabine), the treatment group was exposed to FUS (frequency 0.35 MHz, mechanical index 0.5, pulse length 2.9 ms (1000 cycles), pressure amplitude 0.3 MPa and MBs (SonoVue) for 35 min). …”
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Binderless MDF from Hydroxymethylated Kenaf Pulp by Nyoman J Wistara, Wulan Starini, Fauzi Febrianto, Gustan Pari

“…Wet process was applied to produce MDF (30 cm x 30 cm x 1 cm) with target density of 0.65 g/cm³. Physical and mechanical properties of MDF were measured in accordance with the standard procedure of JIS A 5905: 2003. …”
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Analysis of the risk of early postoperative complications after Bentall procedure by V.A. Tymoshenko, B.M. Todurov

“…Acute renal failure was recorded 4.3 times (p = 0.0002) and acute respiratory failure was recorded 3.3 times more often (p = 0.0004). The duration of mechanical ventilation (OR 1.204 (CI 1.053–1.377), p = 0.007) and the development of acute renal failure (OR 4.069 (CI 1.040–15.923), p = 0.044) were two independent predictors of prolonged stay of patients in ICU. …”
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Lidocaine could promote the cuproptosis through up-regulating the long noncoding RNA DNMBP-AS1 in Hep-2 cells by Wei Liu, Yi Yu, Yi He, Meihong Lv

“…In this study, we explored the biological effects of lidocaine on cuproptosis in Hep-2 cells and studied the relevant mechanisms. Methods quantitative RT-PCR was used to measure the expression level of long noncoding RNA (IncRNA) DNMBP-AS1. …”
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Paddy straw collector-cum-chopper for in situ paddy straw management: A sustainable approach by Mohd. Muzamil, Indra Mani, Sehreen Rasool, Livleen Shukla, Shyam Nath

“…The intention was to increase the amount of straw cut at size below 5 cm for nutrient recycling.Method A paddy straw collector-cum-chopper comprised of three sub-systems i.e. straw collection and conveying unit, straw chopping device and discharging mechanism was designed and developed. The performance evaluation, economic assessment of paddy straw collector-cum-chopper and fertility status of soil was recorded.Results The results revealed that operating the machine at 40% moisture content, forward speed 3 kmph and 40 cm height of cut resulted into percentage of paddy straw <5 cm, 5-10 cm, 10-15 cm and > 15 cm as 63.5 %, 8.12 %, 6.44 % and 17.92 percent. …”
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Future destinations: how people cured of hepatitis C using direct acting antiviral drugs progress in a new HCV-free world. A thematic analysis by Sarah R. Donaldson, Andrew Radley, John F. Dillon

“…Concern about the transmission of HCV resulted in self-imposed isolation which weakened support structures. Cure provides a mechanism to strengthen family bonds, however social networks in the wider community remain limited. …”
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TTSNet: Transformer–Temporal Convolutional Network–Self-Attention with Feature Fusion for Prediction of Remaining Useful Life of Aircraft Engines by Zhaofei Li, Shilin Luo, Haiqing Liu, Chaobin Tang, Jianguo Miao

“…The model further completes feature dimension weight allocation and fusion through a multi-head self-attention mechanism, emphasizing the contribution of different features to the model. …”
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Compound exposure of 2.8 GHz and 9.3 GHz microwave causes learning and memory impairment in rats by Liu Sun, Xiaoya Wang, Ke Ren, Chuanfu Yao, Haoyu Wang, Xinping Xu, Hui Wang, Ji Dong, Jing Zhang, Binwei Yao, Xiaohui Wei, Ruiyun Peng, Li Zhao

“…However, both the cognitive function and hippocampal structure restored to normal at 28 d after exposure, which might be attributed to self-recovery mechanisms. Gene ontology (GO) and Protein-protein interaction (PPI) analyses of differential expressed genes (DEGs) in peripheral blood suggested that Htt and Bdnf might be potential indicators to predict microwave. …”
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Olopatadine Suppresses the Migration of THP-1 Monocytes Induced by S100A12 Protein

“…These results suggest that olopatadine has a new mechanism of action, that is, suppression of the function of S100A12, in addition to histamine <mml:math alttext="$mathrm{H}_{1}}$"> <mml:mrow> <mml:msub> <mml:mtext>H</mml:mtext> <mml:mn>1</mml:mn> </mml:msub> </mml:mrow> </mml:math> receptor antagonistic activity.…”
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Fructose 1,6-bisphosphatase 1 is a potential biomarker affecting the malignant phenotype and aerobic glycolysis in glioblastoma by Weihong Lu, Guozheng Huang, Yihan Yu, Xia Zhai, Xiangfeng Zhou

“…Background Fructose 1,6-bisphosphatase 1 (FBP1) has been considered as a potential prognostic biomarker in glioblastoma (GBM), and this study explored the underlying mechanism. Methods The expression and effect of FBP1 expression on the prognosis of GBM patients were examined applying bioinformatics analyses. …”
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IL-17 Mildly Rescued the Impaired Proliferation of Alveolar Epithelial Cells Induced by LCN2 Overexpression by Tingting Lv, Ziliang Hou, Kaiyuan Yang, Jinxiang Wang

“…Lipocalin-2 (LCN2) participates in multiple processes regulating the pathological process of alveolar epithelial cells, but the mechanisms involved are still unclear. Method. We used a BLM-treated mouse model to characterize the expression of LCN2 in lung fibrosis regions and analyzed the location of LCN2 in alveolar epithelial cells. …”
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OSM May Serve as a Biomarker of Poor Prognosis in Clear Cell Renal Cell Carcinoma and Promote Tumor Cell Invasion and Migration by Shuzhang Wei, Yin Chen, Xiaokai Shi, Li Zuo, Lifeng Zhang

“…Finally, the oncogenic mechanisms associated with OSM in ccRCC were explored through signaling pathway enrichment and single-cell analysis. …”
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Methodical approaches in experimental modelling of non-alcoholic fatty liver disease by N. V. Bivalkevich, Yu. K. Denisenko, T. P. Novgorodtseva

“…It is necessary to choose the optimal way of NAFLD modelling, allowing to reveal certain part of pathologic mechanisms of disease and to determine strategy of hepatotropic treatment according to determined task.…”
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Why issue green bonds? Examining their dual impact on environmental protection and economic benefits by Di Zhou, Alexios Kythreotis

“…Finally, the paper recommends that policymakers strengthen carbon reduction policies, establish mechanisms to prevent greenwashing, and integrate CO2 emissions and ESG factors into assessment systems. …”
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Fetuin-B and oxidative stress disrupt placental trophoblasts during maternal undernourishment by Mia Camilliere, Marella R. Verde, Michael S. Wolin, May M. Rabadi, Brian B. Ratliff

“…MUN and fetuin-B reduced mitochondrial metabolism and function, promoting mitochondrial dysregulation and superoxide generation in MUN trophoblasts.Conclusions Our study sheds light on the mechanisms responsible for MUN-induced placental insufficiency while identifying therapeutic agents as possible add-on interventions.…”
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Probiotic Bacterium-Derived p40, p75, and HM0539 Proteins as Novel Postbiotics and Gut-Associated Immune System (GAIS) Modulation: Postbiotic-Gut-Health Axis by Feray Gençer Bingöl, Duygu Ağagündüz, Ferenc Budán

“…The p40 protein, in particular, has been shown to support gut barrier activity and reduce inflammation, potentially through mechanisms involving epidermal growth factor receptor-dependent signaling. …”
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Effect of Electroacupuncture at Baihui and Shenting on Learning and Memory of Cerebral Ischemia-reperfusion Injuried Rats Via Magnetic Resonance Spectroscopy by Congkuai ZHAO, Weilin LIU, Ruhui LIN, Jing TAO

“…Objective:To observe the nerve cell metabolism of hippocampus in focal cerebral ischemia/reperfusion (FCIR) rats, and explore the mechanism of electroacupuncture (EA) improving the learning and memory ability of FCIR rats.Methods:Sprague-dawley (SD) rats were randomly divided into sham operated group, model group and EA group. …”
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Theoretical Study of Sphingomyelinases from <i>Entamoeba histolytica</i> and <i>Trichomonas vaginalis</i> Sheds Light on the Evolution of Enzymes Needed for Survival and Colonizati... by Fátima Berenice Ramírez-Montiel, Sairy Yarely Andrade-Guillen, Ana Laura Medina-Nieto, Ángeles Rangel-Serrano, José A. Martínez-Álvarez, Javier de la Mora, Naurú Idalia Vargas-Maya, Claudia Leticia Mendoza-Macías, Felipe Padilla-Vaca, Bernardo Franco

“…Pathogens require a set of enzymes for tissue damage generation and to obtain nourishment, as well as a toolbox full of alternatives to bypass host defense mechanisms. Our group has shown that the parasitic protist <i>Entamoeba histolytica</i> encodes for 14 sphingomyelinases (SMases); one of them (acid sphingomyelinase 6, aSMase6) is involved in repairing membrane damage and exhibits hemolytic activity. …”
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The necessity of cell banks by A. G. Menzorov, O. L. Serov

“…In addition, CRISPR/Cas could be used to introduce practically any mutations into iPSCs for the creation of disease-specific model cell lines that would facilitate disease mechanism studies and pharmaceutical drug testing. …”
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Calponin 3 Regulates Myoblast Proliferation and Differentiation Through Actin Cytoskeleton Remodeling and YAP1-Mediated Signaling in Myoblasts by Mai Thi Nguyen, Quoc Kiet Ly, Thanh Huu Phan Ngo, Wan Lee

“…CNN3 knockdown led to a marked increase in filamentous actin, which promoted the nuclear localization of Yes-associated protein 1 (YAP1), a mechanosensitive transcriptional coactivator required for response to the mechanical cues that drive cell proliferation. Subsequently, CNN3 depletion enhanced myoblast proliferation by upregulating the expression of the YAP1 target genes related to cell cycle progression, such as cyclin B1, cyclin D1, and PCNA. …”
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