A novel conceptual model for Dansgaard–Oeschger event dynamics based on ice-core data by J. O. Melcher, S. Halkjær, P. Ditlevsen, P. L. Langen, G. Vettoretti, S. O. Rasmussen

“…The study provides new insights into the underlying mechanisms driving these highly significant climate phenomena and the necessary timescale in which they are forced by allowing the new model's parameters to vary through time. …”
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Interplay between circulating von Willebrand factor and neutrophils: implications for inflammation, neutrophil function, and von Willebrand factor clearance by Alua Kuanyshbek, Hamideh Yadegari, Jens Müller, Nasim Shahidi Hamedani, Samhitha Urs Ramaraje, Johannes Oldenburg

“…Importantly, we have identified neutrophils as potential cellular mediators involved in the clearance of VWF from circulation, introducing a novel mechanism for VWF removal. …”
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STAT3-Inducible Mouse ESCs: A Model to Study the Role of STAT3 in ESC Maintenance and Lineage Differentiation by Yu Qian Wong, Hongyan Xu, Qiang Wu, Xinyu Liu, Chengchen Lufei, Xiu Qin Xu, Xin-Yuan Fu

“…Taken together, the findings of this study indicated that InSTAT3 KO and InSTAT3 CA ESCs could provide a new tool to clarify the direct targets of STAT3 and its role in ESC maintenance, which will facilitate the elaboration of the mechanisms whereby STAT3 maintains ESC pluripotency and regulates ESC differentiation during mammalian embryogenesis.…”
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Test on Compaction Reinforcement Effect of Sand by Lianzhen Zhang, Qingsong Zhang, Zhipeng Li, Hongbo Wang

“…Results show that compaction can effectively improve the mechanical properties and impermeability properties of sand. …”
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Pan-cancer analysis and single-cell analysis identifies the CENPN as a biomarker for survival prognosis and immunotherapy by Nie Zhang, Zhuoying He, Xuejin Qin, Ke Han, Zhengchun Zhu, Fei Zhong

“…Despite its potential importance, the precise functional role and regulatory mechanisms of CENPN in diverse malignancies remain largely unexplored. …”
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Wind Turbine Electrical Energy Supply System for Oil Well Heating by A. A. Belsky, V. A. Morenov, K. S. Kupavykh, M. S. Sandyga

“…The heating element of the system can be used in the wells exploited by freeflow, gas lift and mechanized methods, while its installation does not require an overhaul. …”
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Advancing Alzheimer’s Diagnosis: The Role of AI - A Review by Dominka Rehan, Sven Solisch, Anna Blazhkova, Anna Susłow, Adam Szwed, Ewa Szczęsna

“…An aging society therefore poses a huge challenge to medicine. The exact mechanism responsible for this disease is still not fully understood. …”
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Enhancing Underwater Video from Consecutive Frames While Preserving Temporal Consistency by Kai Hu, Yuancheng Meng, Zichen Liao, Lei Tang, Xiaoling Ye

“…It utilizes an attention mechanism to adaptively adjust the weights of different regions in the feature map, thereby effectively enhancing key regions within underwater video frames. …”
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Overexpressed Neuropilin-1 in Endothelial Cells Promotes Endothelial Permeability through Interaction with ANGPTL4 and VEGF in Kawasaki Disease by Junhua Huang, Shuwan Zhang

“…Disrupted endothelial permeability plays a crucial role in the vasculitis pathogenesis of Kawasaki disease (KD), which leads to pathological vascular leak and facilitates inflammatory cell infiltration in vascular lesions; however, the mechanisms involved in the development of endothelial barrier dysfunction during KD vasculitis are still largely unclear. …”
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SNP rs9364554 Modulates Androgen Receptor Binding and Drug Response in Prostate Cancer by Yuqian Yan, Lei Shi, Tao Ma, Liguo Wang, Haojie Huang

“…More importantly, we found that this SNP has different binding affinities with transcription factors, specifically FOXA1 and AR, which significantly affects their regulation of <i>SLC22A3</i> transcription. (4) Conclusions: Our findings highlight the potential of using this SNP as a biomarker for predicting chemotherapeutic outcomes and uncover possible mechanisms underlying drug resistance in advanced prostate cancers. …”
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Characteristics and Emerging Trends in International City Negotiations by M. I. Kolykhalov

“…At the international level, there are several specialized institutions and mechanisms that allow cities to coordinate their positions and develop common approaches. …”
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Freedom of Expression in the US Constitution: Formation and Development by O. V. Sendetskaya

“…The author has argued in favor of the fact that Ukraine should take into account the American approach to the protection of the right to freedom of expression and freedom of speech, as well as to establish a mechanism for their observance as fundamental personal human and civil rights.…”
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Development of sustained-release extemporaneous moxifloxacin loaded commercial soft hydrogel contact lenses by Duy Toan Pham, Pratthana Chomchalao, Kunasin Bunneramit, Phurichaya Kladcharoen, Rossukon Khotcharrat, Waree Tiyaboonchai

“…Kinetically, both the moxifloxacin loading and releasing processes followed the Higuchi model, with the diffusion mechanism governing the drug behaviors. Isothermally, the moxifloxacin molecules were adsorbed onto the contact lenses surfaces via physical adsorptions by weak interactions of van der Waals forces, ionic bonding, and hydrophobic interactions. …”
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Association of blood pressure and left ventricular mass with subclinical coronary atherosclerosis by Weiting Huang, Calvin Chin, Rehena Sultana, Chirk Jenn Ng, Jonathan Jiunn Liang Yap, Enver De Wei Loh, Swee Yaw Tan, Siew Ching Kong, Khung K Yeo

“…Background Left ventricular (LV) mass is closely associated with atherosclerotic heart disease, but the mechanisms are not well defined. This study aimed to evaluate the risk factors associated with LV mass and subclinical coronary atherosclerosis, in an Asian population free of baseline cardiovascular disease.Methods The SingHEART study is a population-based cohort in which individuals underwent ambulatory blood pressure (BP) monitoring, cardiac MRI to measure indexed LV mass index (LVMI) and coronary artery calcium (CAC) scoring. …”
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Organic pollutant oxidation on manganese oxides in soils – the role of calcite indicated by geoelectrical and chemical analyses by S. S. Altzitser, Y. G. Mishael, N. Schwartz

“…We aim to shed light on the underlying mechanisms of hydroquinone (a representative phenolic pollutant) oxidation in ambient, MnO<span class="inline-formula">₂</span>-rich sandy soil within soil columns designed for breakthrough experiments. …”
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Detection of AdeAB, TetA, and TetB efflux pump genes in clinical isolates of tetracycline-resistant Acinetobacter baumannii from patients of Suez Canal University Hospitals by Hasnaa Azab, Aya Mohamed Askar, Noha M. Abd El-Fadeal, Amira A. A. Othman, Amal H. Rayan, Sally Khattab

“…Conclusions Efflux pump is an important mechanism for tetracycline resistance among A. baumannii isolates.…”
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Epigenetic modulation of social cognition: exploring the impact of methylation in brain-derived neurotrophic factor and oxytocin receptor genes across sex by Hye Yoon Park, Suonaa Lee, Se Jun Koo, Zhenxu Li, Eunchong Seo, Eun Lee, Suk Kyoon An

“…Abstract Social cognition, which ranges from recognizing social cues to intricate inferential reasoning, is influenced by environmental factors and epigenetic mechanisms. Notably, methylation variations in stress-related genes like brain-derived neurotrophic factor (BDNF) and the oxytocin receptor (OXTR) are linked to distinct social cognitive functions and exhibit sex-specific differences. …”
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Diffusion Partition Consensus: Diffusion-Aided Time-of-Flight Estimates, Anomaly Detection, and Localization for Ultrasonic Nondestructive Evaluation Data by Nick Torenvliet, John S. Zelek

“…The quality of results, the checks and balances provided by the fault diagnosis mechanism, and the opportunity to include a human in the loop, support the case for usage in safety-critical contexts such as NDE at a nuclear power facility.…”
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FEAR PHENOMENON IN EXISTENTIAL PHILOSOPHY by V. V. Melnyk

“…The author emphasizes that the fear is objectified in the culture and is amenable to the mechanism of minimization. Great attention is paid to the provocation of the depression by fear. …”
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A Bibliometric Analysis of Macrophage Research Associated with Periodontitis Over the Past Two Decades by Yu Qiu, Zhenzhen Ding, Deqin Yang

“…Co-citation analysis indicated that researchers primarily investigate the mechanisms of macrophages in periodontitis through both in vivo and in vitro experiments. …”
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