Exposure to specific polyfluoroalkyl chemicals is associated with cardiovascular disease in US adults: a population-based study by Wenwen Xiao, Guojin Jian, Fei Ma, Hong Li, Xiaohong Yang, Hengyang Zhang, Yongping Cao

“…Our study provided important evidence for probing the impact of PFCs on CVD and laid a foundation for further mechanism research.…”
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Fine Particulate Matter Deposition in 3D Out-of-Plane Bifurcation Lung Airway by Chun-Chih Chuang, Justus Kavita Mutuku, Chih-Che Chueh, Anurita Selvarajoo, Wei-Hsin Chen

“…Abstract Fine particulate matter (PM2.5) produced from traffic-loaded urban areas, combustion processes during industrial processes, and dust resuspension during mechanical disturbances may cause considerable health hazards when it is inhaled, owing to an enhanced accumulation of this particulate material in the lung. …”
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Hydrogen sulfide attenuates disturbed flow-induced vascular remodeling by inhibiting LDHB-mediated autophagic flux by Xia Wang, Xiying Huang, Yongya Zhang, Huanhuan Huo, Guo Zhou, Linghong Shen, Long Li, Ben He

“…These data identify a molecular mechanism by which H2S attenuates DF-induced vascular remodeling by inhibiting LDHB and disrupting the interaction between LDHB and ATP6V1A, thereby impeding the autophagy process. …”
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Physical Pathways for JWST-observed Supermassive Black Holes in the Early Universe by Junehyoung Jeon, Volker Bromm, Boyuan Liu, Steven L. Finkelstein

“…We assess whether the conditions for such enhanced accretion rates are realistic by considering limits on plausible transport mechanisms. We also examine various DCBH growth histories and find that mass growth is more sustained in overdense cosmological environments, where high gas densities are achieved locally. …”
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Relationship of Secondary School Mathematics Achievement with Engineering Mathematics 2 in Polytechnics by Husnira Binti Hussin, Marina Binti Majid, Rohayu Binti Ab Wahab

“…The research used secondary data obtained from the examination unit from 2442 students of Semester 2 of Diploma in Civil Engineering (JKA), Diploma in Electrical Engineering (JKE) and Diploma in Mechanical Engineering JKM) at Polytechnic Sultan Mizan Zainal Abidin (PSMZA). …”
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Research on vehicle feature recognition algorithm based on optimized convolutional neural network by Xuan CHEN, Jiyi WU

“…To address the issue of weak identification and low accuracy in recognizing features of target vehicles at different distances in road scene images, a vehicle feature recognition algorithm based on optimized convolutional neural network (CNN) was proposed.Firstly, a multi-scale input based on the PAN model was employed to capture target vehicle features at varying distances.Subsequently, improvements were made to the network model by incorporating multi-pool, batch normalization (BN) layers, and Leaky ReLU activation functions within the CNN architecture.Furthermore, the generalization ability of the network model was enhanced by introducing a hybrid attention mechanism that focuses on important features and regions in the vehicle image.Lastly, a multi-level CNN structure was constructed to achieve feature recognition for vehicles.Simulation experiment results conducted on the BIT-Vehicle database within a single scene show the proposed algorithm’s significant enhancements in single-object and multi-object recognition rates compared to CNN, R-CNN, ABC-CNN, Faster R-CNN, AlexNet, VGG16, and YOLOV8.Specifically, improvements of 16.75%, 10.9%, 4%, 3.7%, 2.46%, 1.3%, and 1% in single-object recognition, as well as 17.8%, 10.5%, 2.5%, 3.8%, 2.7%, 1.1%, and 1.3% in multi-object recognition, have been demonstrated by the proposed algorithm, respectively.Over the more complex UA-DETRAC datasets, more precise results have been also achieved by the proposed algorithm in recognizing target vehicles at various distances compared to other algorithms.…”
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Shedding light on DNA methylation and its clinical implications: the impact of long-read-based nanopore technology by Alexandra Chera, Mircea Stancu-Cretu, Nicolae Radu Zabet, Octavian Bucur

“…Abstract DNA methylation is an essential epigenetic mechanism for regulation of gene expression, through which many physiological (X-chromosome inactivation, genetic imprinting, chromatin structure and miRNA regulation, genome defense, silencing of transposable elements) and pathological processes (cancer and repetitive sequences-associated diseases) are regulated. …”
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Anti-allergic effect of 5,7-dihydroxy-4-methylcoumarin in IgE-mediated RBL-2H3 cells and PCA murine model by Sugeun Gwon, Seong-Ah Shin, Moonsu Kim, Sun Young Moon, Seyeon Choi, Minji Kim, Jun Hyuck Lee, Hyun Ho Park, Chang Sup Lee

“…Although 5,7-dihydroxy-4-methylcoumarin, a phytochemical derivative, has been demonstrated to exhibit antioxidant, anti-apoptotic, and anti-aggregatory effects, its anti-allergic properties and underlying molecular mechanisms remain elusive. Therefore, this study was conducted to investigate the anti-allergic effects of 5,7-dihydroxy-4-methylcoumarin in two experimental models: rat basophilic leukemia-2H3 cells sensitized using dinitrophenyl-specific immunoglobulin E (IgE)/human serum albumin and a passive cutaneous anaphylaxis (PCA) murine model. …”
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Legitimate expectations in civil proceedings: traditional legal understanding and synergetic approach by O. H. Bortnik

“…The results of the study can be used in further research to determine the alleged interpretive mechanisms in civil proceedings that have the purpose of the alleged enforcement. …”
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Tetracyclines in Rheumatoid Arthritis: Dual Anti-Inflammatory and Immunomodulatory Roles, Effectiveness, and Safety Insights by Mislav Radić, Andrej Belančić, Hana Đogaš, Marijana Vučković, Andrea Gelemanović, Andrea Faour, Ivan Vlak, Josipa Radić

“…This narrative review explores their effectiveness, mechanisms of action, safety profiles, and current challenges in RA care. …”
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Analysis and Prediction of Grouting Reinforcement Performance of Broken Rock Considering Joint Morphology Characteristics by Guanglin Liang, Linchong Huang, Chengyong Cao

“…Given the significant influence of rock joint morphology on mechanical behavior, this study employs the frequency spectrum fractal dimension (D) and the frequency domain amplitude integral (Rq) as quantitative descriptors of joint morphology. …”
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Explainable prediction model for punching shear strength of FRP-RC slabs based on kernel density estimation and XGBoost by Sheng Zheng, Tianyu Hu, Nima Khodadadi, Antonio Nanni

“…Abstract Reinforced concrete (RC) slabs are widely used in modern building structures due to their superior properties and ease of construction. However, their mechanical properties are limited by their punching shear strength in the connection region with the columns. …”
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Carboxymethyl cellulose/shellac composite loaded with pomegranate extract and jojoba oil as anti-mycotic and anti-mycotoxigenic food packaging materials by Salah A. A. Mohamed, Amr Farouk, Adel G. Abdel-Razek, El-Shahat Nashy, Mohamed El-Sakhawy, Ahmed Noah Badr

“…The in-silico study revealed that ellagic acid and hesperidin in POE extract, erucic and oleic acids in JOE, and shellac had the highest binding free energies against the vital enzymes involved in bactericidal/bacteriostatic effects and the aflatoxin bio synthetic mechanism.…”
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Flowering characteristics and breeding system of Deutzia parviflora by WANG Qi, LI Jinyu, WANG Xinyi, WANG Yixuan, GUO Wei, YUAN Tao

“…[Conclusion] There is no apomixis in D . parviflora and the breeding system is a mixed mating system, dominanted by outcrossing mechanism, requiring pollinators, and it is more fertile and can be used as a parent for hybrid breeding in the genus Deutzia. …”
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Sex steroid hormones mediate the association between neonicotinoids and obesity among children and adolescents by Qian Su, Jinzhu Luo, You Zhou, Miao Liu, Shaohua Zeng, Yin Li, Jieying Gao

“…Objective: To investigate the association between neonicotinoid exposure and obesity among U.S. children and adolescents and to explore underlying mechanism mediated by serum sex steroid hormones in these associations. …”
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Investigation of Black Carbon Wet Deposition to the United States from National Atmospheric Deposition Network Samples by Piyaporn Sricharoenvech, Ross Edwards, Müge Yaşar, David Gay, James J. Schauer

“…Although wet deposition is considered the primary mechanism for removing BC from the atmosphere, published data is exceptionally scarce. …”
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The Adoption of Bundled Sustainable Farm and Environmental Practices by Coffee Farmers in Southwest Ethiopia by Gezahagn Kudama, Hika Wana, Mabiratu Dangia

“…Providing training and supplementing coffee farmers with farm equipment used for SFEPs, promoting small-scale mechanization options to address seasonal labor constraints, as well as strengthening Fairtrade organizations will facilitate the adoption of multiple SFEPs by coffee farmers in the country.…”
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Bioactive compounds of Calotropis gigantea for cancer treatment by Jayalekshmi C, Nishanth Mohan Das, Rajiv Periakaruppan

“…These bioactive compounds exert their effects through multiple mechanisms, including induction of apoptosis, inhibition of cell proliferation, suppression of angiogenesis, and modulation of immune responses. …”
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Comprehensive profiling of gut bacterial communities in hybrid red tilapia with and without streptococcosis by Pathamawan Amthungphong, Natthaphong Sombuttra, Triwit Rattanarojpong, Kanthida Kusonmano, Saengchan Senapin, Satid Chatchaiphan, Watanalai Panbangred, Jirayut Euanorasetr

“…The gut microbiome is crucial in regulating nutrient metabolism, immune responses, and defense mechanisms against diseases. This study aimed to comprehensively compare bacterial community profiles within the foregut, midgut, and hindgut regions of red tilapia fish with and without streptococcosis. …”
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A rare phenomenon involving ventricular separation: a case report by Huayong Jin, Yudan Wen

“…Case presentation An 82-year-old man with syncope presented to the emergency departmentin a critical condition with no vital signs and was immediately treated via endotracheal intubation, mechanical ventilation, and cardiopulmonary resuscitation.The patient’s electrocardiogram (ECG) showed two completely independent waveforms that were excited at their respective frequencies without interfering with one another, with the overall ECG resembling a third-degree atrioventricular block. …”
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