Protection of Alzheimer’s disease progression by a human-origin probiotics cocktail by Santosh Kumar Prajapati, Shaohua Wang, Sidharth P Mishra, Shalini Jain, Hariom Yadav

“…Although both male and female mice showed overall improvements in cognition and biological markers, females did not exhibit improvements in specific markers related to inflammation and barrier permeability, suggesting that the underlying mechanisms may differ depending on sex. In conclusion, our results suggest that this unique probiotics cocktail could serve as a prophylactic agent to reduce the progression of cognitive decline and AD pathology. …”
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Determination of damaging SNP’s in SHANK3 gene with in silico methods by İrem Gülfem Albayrak, Şeyma Yektar, Süeda Kaya

“…There is considerable evidence associating SHANK3 mutations to autism spectrum disorder; hence, it is worthwhile to investigate the underlying molecular genetic mechanisms of the disease. Results This research uses in silico approaches such as SIFT, PolyPhen-2, I-Mutant 2.0, and Project HOPE to find harmful SNPs, which are the single nucleotide polymorphisms the most prevalent types of genetic variation in humans, in the SHANK3 gene. …”
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A rare case of Ewing's sarcoma in a 4-year-old child treated by tumor endoprosthetics using 3D printing by Vladimir Stavrev, Luben Stokov, Petko Ganev, Georgi Georgiev

“…Future expectations are that non-invasive lengthening mechanisms or a biological approach will be able to meet the special needs of this population. …”
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Multi-Physical Intelligent Analysis of the Thermal-Structural-Optical Coupling for Mirror Based on Surrogate Model by Wenxiong Li, Junli Shen, Zhenyu Lu, Shudong Men, Qingwen Wu

“…The thermal-structural-optical multi-physical coupling analysis (TSO-MCA) of infrared optical systems and their mirrors during the establishment of a cryogenic environment is a complex multi-physical coupling problem involving mechanics, thermal, optics and other factors. Currently, the finite element method’s workflow is complex and cumbersome, and it cannot simulate the continuous process of establishing a cryogenic environment. …”
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Exploring social media appearance preoccupation in relation to self-esteem, well-being, and mental health by Rosa Angela Fabio, Rosa Tripodi

“…Overall, these results provide partial support for the theory of the poor-get-richer hypothesis, suggesting that individuals experiencing heightened levels of appearance-related anxiety may turn to social media as a coping mechanism, potentially exacerbating their psychological distress.…”
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Hydrocarbon contaminated water remediation using a locally constructed multi-stage bioreactor incorporated with media filtration by S. Antwi-Akomea, B. Fei-Baffoe, E.J.D. Belford, M. Borigu

“…Hydrocarbon-eating microbes were isolated from hydrocarbon contaminated soils obtained from selected mechanic workshops. Bamboo chips and coconut husk chips were applied as support media for microbial attachment within the bioreactor compartment of the treatment setup. …”
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The effects of PISA on global basic education reform: a systematic literature review by Jian Li, Eryong Xue, Siyuan Guo

“…We present a specific mechanism model of PISA’s impact on the development of education policies that demonstrates the two-way interaction between PISA and education reform, providing a theoretical reference for future academic research on education reform linked to PISA.…”
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Part 4. Clinical Practice Guideline for Surveillance and Imaging Studies of Trauma Patients in the Trauma Bay from the Korean Society of Traumatology by Sung Wook Chang, Kang Kook Choi, O Hyun Kim, Maru Kim, Gil Jae Lee, Korean Society of Traumatology (KST) Clinical Research Group

“…It is not necessary to perform chest CT as an initial examination in all patients with suspected chest injury, but in cases of suspected vascular injury in patients with thoracic or high-energy damage due to the mechanism of injury, chest CT can be considered for patients in a hemodynamically stable condition (2B). …”
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DECTNet: A detail enhanced CNN-Transformer network for single-image deraining by Liping Wang, Guangwei Gao

“…In the ERFDB, we introduce a mixed attention mechanism, incorporating channel information-enhanced layers within the residual feature distillation structure. …”
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Performance Evaluation and Site Application of a Hydrophobic Long-Chain Ester-Based CO2 Fracturing Fluid Thickener by Jianqiang Lu, Meilong Fu, Liu Xu, Qian Huang, Yan Zheng

“….), the authors have synthesized the novel hydrophobic long-chain ester thickener, studied viscosity, frictional drag, and proppant-carrying capacity of CO2 fracturing fluid and core damage by CO2 fracturing fluid by varying the temperature, pressure, and level of injection of the novel thickener and explored the thickening mechanism for this thickener in CO2. Based on the study results, as the temperature, pressure, and amount of injected thickener increased, fracturing fluid viscosity increased steadily. …”
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Risk factors for African swine fever spread in wild boar in the Russian Federation by O. I. Zakharova, A. A. Blokhin, O. A. Burova, I. V. Yashin, F. I. Korennoy

“…However, on the whole, for all the infected Subjects, the regression model demonstrated the failure of the wild boar population density factor to explain the observed ASF outbreak distribution, and this may be indicative of the existence of other epizootic drivers of the disease spread in the wild. One of such mechanisms may be the persistence of infectious potential in the external environment and in the formed stationary local foci of African swine fever, despite the anti-epizootic measures taken, including the measures aimed at regulating the number of susceptible population – depopulation.…”
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Influence of gaps in flange joints on the stress-strain state of the unit by A. R. Tusnin, V. D. Platonova

“…A test of a stud with the declared strength class 8.8 to determine its actual mechanical characteristics, a tensile test of a stud with slots to assess the reliability of strain gauge data and adjust the design of experimental specimens taking into account the test results, testing of joint solutions of two types of configurations, processing and analyzing the test results were carried out.Conclusions. …”
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Apply a deep learning hybrid model optimized by an Improved Chimp Optimization Algorithm in PM2.5 prediction by Ming Wei, Xiaopeng Du

“…After the LSTM, an Attention Mechanism is incorporated to assign different weights to the input features, emphasizing the role of the important features. …”
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Kriminalpolitik - straffrättspolitik by Tapio Lappi-Seppälä

“…The paper also discusses important reforms to the present crime policy, the role of the criminal law as distinguished from other crime policy mechanisms, the aims and functions of the penal system, and foreseeable problems ("risk factors'') that may threaten the basic tenets of humane and rational crime policy.…”
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miR-223 promotes cartilage differentiation of bone marrow-derived mesenchymal stem cells and protects against osteoarthritis by suppressing NLRP-3 expression by Nan Min, Jie Ma, Lei Shi, Lin Wang, Chi Liu, Yaonan Zhang, Qingyun Xue

“…Introduction The present investigation evaluates the role of miR-223 mimic in the treatment of osteoarthritis (OA) and postulates the possible molecular mechanism of its action. Material and methods Bone marrow-derived mesenchymal stem cells (BMSCs) were isolated from rats and cultured in chondrogenic medium to stimulate the differentiation of chondrocytes. …”
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Simulation Analysis of Energy Inputs Required by Agricultural Machines to Perform Field Operations by Francesco Paciolla, Katarzyna Łyp-Wrońska, Tommaso Quartarella, Simone Pascuzzi

“…Moreover, considering the operational efficiency of the systems, an analysis of the available mechanical work supplied by the fuel was conducted.…”
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Additively manufactured stochastic and gyroid scaffold design towards osseointegration and bone regeneration in a rabbit femur model by Susheem Kanwar, Oraib Al-Ketan, Gopinathan Janarthanan, Sanjairaj Vijayavenkataraman

“…The titanium alloy samples used for in vivo testing were evaluated for their mechanical properties which were in the range of the native trabecular bone and supported statistically significant cell growth. …”
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Similar Conditions With Opposite Effects: Predation‐Risk Effects on Prey Abundance Are Highly Contingent by Scott D. Peacor, Clayton E. Cressler, Kevin L. Pangle, Alexandra V. Rafalski, Chao Song, Earl E. Werner

“…Our results highlight the potentially profound context dependence of risk effects: risk effects on the density of some zooplankton species varied between a significant negative effect in one experiment to a significant positive effect in another, whereas other species showed significant negative or positive effects in one experiment and no effect in another. We review mechanisms that could underlie risk effects having opposite effects on the same prey. …”
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Real-Life Use of Tocilizumab in the Treatment of Severe COVID-19 Pneumonia by Ruth Alex, Shabaz Mohiuddin Gulam, Kiran Kumar

“…In our analysis, patients who were mechanically ventilated at the time of administration of TCZ had a significantly higher risk of death by day 28. …”
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Young TPI: empowering animal-free science among the next- generation of scientists by Marta G. Valverde, Marta G. Valverde, Fatima Zohra Abarkan, Fatima Zohra Abarkan, Rebecca Van Eijden, Rebecca Van Eijden, Julia M. L. Menon, Julia M. L. Menon, Nikolas Gaio, Nikolas Gaio, Aarti Ramchandran, Aarti Ramchandran, Victoria C. De Leeuw, Victoria C. De Leeuw

“…This manuscript describes the conception, establishment, and progress of Young TPI from its start to present, detailing its strategy for communication, activities, and funding mechanisms, and ongoing endeavors to enlist new members and forge strategic alliances in pursuit of its mission.…”
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