Current molecular understanding of central nervous system schwannomas by Takahiro Tsuchiya, Satoru Miyawaki, Yu Teranishi, Kenta Ohara, Yudai Hirano, Shotaro Ogawa, Seiei Torazawa, Yu Sakai, Hiroki Hongo, Hideaki Ono, Nobuhito Saito

“…Conclusion A deeper exploration of these molecular findings could clarify the mechanisms of schwannoma tumorigenesis and progression, ultimately guiding the development of new therapeutic targets. …”
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A review of parameter settings for galvanic vestibular stimulation in clinical applications by Yishai Valter, Yishai Valter, Linda Vataksi, Aaron R. Allred, Jeffrey R. Hebert, Tad T. Brunyé, Tad T. Brunyé, Torin K. Clark, Jorge Serrador, Abhishek Datta, Abhishek Datta

“…This study aims to review the parameters used in various treatment applications while also providing a concise overview of the mechanisms underlying GVS thereby offering essential context and justification for the chosen parameters. …”
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TMEM97 governs partial epithelial-mesenchymal transition of retinal pigment epithelial cells via the CTNND2-ADAM10 axis by Jing Li, Yosuke Nagasaka, Hongtao Shen, Xinyu Zhou, Jianjie Ma, Dilza Trevisan-Silva, Nicholas E. Sherman, Jayakrishna Ambati, Bradley D. Gelfand, Lian-Wang Guo

“…Here, we link TMEM97 to pEMT in RPE cells and explore the underlying molecular mechanisms. We found that re-expressing TMEM97 in the RPE of TMEM97-knockout mice, via subretinal lentiviral delivery, mitigated oxidant (NaIO3)-induced photoreceptor loss. …”
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A Method for Tomato Ripeness Recognition and Detection Based on an Improved YOLOv8 Model by Zhanshuo Yang, Yaxian Li, Qiyu Han, Haoming Wang, Chunjiang Li, Zhandong Wu

“…By incorporating attention mechanisms across three dimensions—color, channel, and spatial attention—the model’s ability to recognize changes in tomato color and spatial positioning is improved. …”
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Rheumatoid Arthritis, Circulating Inflammatory Proteins, and Hypertension: A Mendelian Randomization Study by Guobing Jia, Tao Guo, Lei Liu, Chengshi He

“…These findings provide new evidence supporting the inflammatory hypothesis in the mechanism of hypertension. Inflammatory factors may serve as potential targets for antihypertensive therapy.…”
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Gut microbiota and atrial cardiomyopathy by Tingting Sun, Beibei Song, Bo Li

“…The aim of this work is to bridge the knowledge gap regarding the interactions between the gut microbiota and atrial cardiomyopathy, with a particular focus on elucidating the mechanisms by which gut dysbiosis may induce atrial remodeling and dysfunction. …”
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Anticancer Potential of Fruit Extracts from Vatica diospyroides Symington Type SS and Their Effect on Program Cell Death of Cervical Cancer Cell Lines by Atchara Chothiphirat, Kesara Nittayaboon, Kanyanatt Kanokwiroon, Theera Srisawat, Raphatphorn Navakanitworakul

“…Vatica diospyroides Symington is locally known as Chan-Ka-Pho in Thailand. Ancient people have used it as therapeutic plant for cardiac and blood tonic cure. …”
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Strain rate dependence of dynamic recrystallization and texture evolution in hot compressed Mg-Gd-Er-Zr alloy by Ning Ding, Wenbo Du, Shubo Li, Ke Liu, Xian Du, Zijian Yu

“…In this work, the DRX behavior and texture evolution of Mg-8Gd-1Er-0.5Zr alloy hot compressed with strain rates of 0.1 s−1, 1 s−1, 10 s−1 and 50 s−1 are studied, and the corresponding dominant mechanisms for DRX and texture weakening are discussed. …”
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Drug-induced heart failure: a real-world pharmacovigilance study using the FDA adverse event reporting system database by Youqi Huang, Youqi Huang, Xiaowen Chen, Xiaowen Chen, Mingyu Chen, Mingyu Chen, Yuze Lin, Yuze Lin, Bingqi Chen, Hongjin Gao, Min Chen

“…These findings contribute to a better understanding of drug-induced HF and provide a basis for future research on its underlying mechanisms.…”
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Progress in devulcanization of waste tire rubber: Upcycling towards a circular economy by Zaheer ul Haq, Teng Ren, Xinyan Yue, Krzysztof Formela, Denis Rodrigue, Xavier Colom Fajula, Tony McNally, Dong Dawei, Yong Zhang, Shifeng Wang

“…It explores the intricacies of ground tire rubber as a starting material, structural evolution of ground tire rubber during the devulcanization process and the associated challenges in achieving efficient devulcanization while retaining desirable mechanical properties. Furthermore, through an in-depth analysis of recent advancements, limitations and prospects, this paper offers a complete understanding of the challenges faced in tire rubber devulcanization. …”
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Recent updates of centromere proteins in hepatocellular carcinoma: a review by Zhongyuan Yang, Wenjiao Chen, Yunhui Liu, Yuxin Niu

“…Since the pathogenesis of HCC is not yet clear, identifying the molecular mechanisms and therapeutic targets related to it is crucial. …”
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3-Hydroxybutyrate alleviates septic liver injury by promoting macrophage polarization from M1 to M2 by Hu Jingjuan, Deng Fan, Sun Qishun, Min Yue, Feng Siyuan, Wu Ling, Chen Xiaofeng, Liu Kexuan

“…Objective To investigate the therapeutic effects and underlying mechanisms of the metabolite 3- hydroxybutyrate (3HB) in a cecal ligation and puncture (CLP)-induced sepsis model in mice. …”
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Intravoxel incoherent motion (IVIM) MRI-derived masseter muscle characteristics: a new diagnostic marker in head and neck cancer? by Kai-Lun Cheng, Hsueh-Ju Lu, Chao-Yu Shen, Chia-Wei Lin, Hui-Yu Wang, Ying-Hsiang Chou, Yeu-Sheng Tyan, Ping-Huei Tsai

“…The clinical implications and underlying mechanisms of these findings of distinct perfusion changes warrant further exploration.…”
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Future anxiety and the motives for postponing parenthood: generational time perspective and life satisfaction as mediators by Małgorzata Szcześniak, Celina Timoszyk-Tomczak, Julia Łoś, Monika Grzeczka

“…However, little is known about the reasons and relevant mechanisms that are involved in people’s decisions to delay parenthood. …”
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Irisin Exerts Neuroprotective Effects on Cultured Neurons by Regulating Astrocytes by Kexin Wang, Hongyan Li, Hongxing Wang, Jun-hui Wang, Feng Song, Yu Sun

“…In the present study, we investigated whether irisin could protect neurons against Aβ- (25–35) induced cell damage and explored the possible underlying mechanisms. Primary cell cultures of astrocytes and neurons were established. …”
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Analyzing exosomal miRNA profiles in tetralogy of fallot fetuses’ amniotic fluid by Hainan Yang, Yadan Li, Qiuyue Chen, Shangqing Li, Yiru Yang, Guorong Lyu

“…A dual-luciferase reporter assay confirmed TBX5 as a direct target of miR-10a-5p, suggesting a regulatory mechanism involving their interaction. In summary, our study demonstrates that miR-10a-5p may contribute to the pathogenesis of TOF by impairing cardiomyocyte differentiation through direct targeting of TBX5. …”
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HnRNPR-mediated UPF3B mRNA splicing drives hepatocellular carcinoma metastasis by Hong Wang, Dong Qian, Jiabei Wang, Yao Liu, Wenguang Luo, Hongyan Zhang, Jingjing Cheng, Heng Li, Yang Wu, Wuhan Li, Jing Wang, Xia Yang, Tianzhi Zhang, Dong Han, Qinyao Wang, Chris Zhiyi Zhang, Lianxin Liu

“…RNA immunoprecipitation, and in vitro and in vivo models were used to explore the role of UPF3B-S and the underlying mechanisms. Results: We show that splicing factor HnRNPR binds to the pre-mRNA of UPF3B via its RRM2 domain to generate an exon 8 exclusion truncated splice variant UPF3B-S. …”
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Augmenter of Liver Regeneration Crotonylation Assists in Mitochondria-ER Contact to Alleviate Hepatic SteatosisSummary by Xiao-lin Wang, Jia-hao He, Ping Xie, Yuan Wu, Ling-yue Dong, Wei An

“…Conclusions: The insufficient ALR crotonylation might be a crucial mechanism contributing to the pathogenesis of MASLD. …”
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Modern theory and practice of concrete technology for 3D printing in construction by A. S. Inozemtcev

“…To achieve maximum mechanical properties of printed structures, multicriteria optimization is required, taking into account rheological requirements for mixtures, reinforcement peculiarities and due to the arrangement of metal elements and the adhesion strength of layers. …”
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The role of cyclooxygenase-2 (COX-2) and inflammatory markers in the progress of Alport syndrome in Egyptian children by Moushira Zaki, Hisham A. Orban, Mohamed A. Shahba, Rehab S. I. Moustafa, Ahmed Adel, Fatina I. Fadel, Abeer Selim, Hala T. El-Bassyouni, Eman R. Youness

“…This contributes to the pathogenic mechanisms and advancement of the disease in Alport syndrome. …”
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