Approximate solution of plastic zone in surrounding rock under three-dimensional stress field based on Drucker-Prager strength criterion by LIU Hongtao, LIANG Jialu, HAN Zijun, LIU Qinyu, QIAO Zhongjin

“…This study proposes to address the stability of roadway surrounding rock under three-dimensional stress field based on the Drucker-Prager criterion and the theory of elastic-plastic mechanics. Specifically, we deduced the boundary equation of plastic zone of roadway surrounding rock under three-dimensional stress field by introducing the axial stress solution, and analyzed the shape and size of plastic zone of surrounding rock under different stress field conditions. …”
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Sequence Stratigraphy Variation and Its Implication in Shale Oil Exploration: A Case Study of the Eocene Dongying Depression, Eastern China by Jing Wu, Wei Li, Wenjin Li, Wei Chen

“…Their enrichment affects the hydrocarbon generation capacity and reservoir development of shales. The development mechanism of sequence stratigraphy and the influence of sequence stratigraphy on OM enrichment and carbonate deposition are investigated in this study. …”
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Epigenetic regulation of banana fruit ripening: global and specific DNA methylation profile, and characterization of DNA methylation-related genes by Dina Hermawaty, Mita Azzahra Putri, Sekar Prabhandiya, Fenny Martha Dwivany, Karlia Meitha

“…The study highlights that DNA methylation regulation precedes visible physiological changes in ripening, offering insights into the molecular mechanisms governing fruit ripening and potential strategies to enhance quality and extend shelf life.…”
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Macrophage Activities in Myocardial Infarction and Heart Failure by Sophia Esi Duncan, Shan Gao, Michael Sarhene, Joel Wake Coffie, Deng Linhua, Xingru Bao, Zhang Jing, Sheng Li, Rui Guo, Jing Su, Guanwei Fan

“…HF is an established frequent complication of myocardial infarction (MI), and numerous influences including persistent myocardial ischemia, shocked myocardium, ventricular remodeling, infarct size, and mechanical impairments, as well as hibernating myocardium trigger the development of left ventricular systolic dysfunction following MI. …”
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Understanding the potential impact of trimester-specific maternal immune activation due to SARS-CoV-2 on early human neurodevelopment and the role of cytokine balance by Alexandre Díaz-Pons, Sergio Castaño-Castaño, Víctor Ortiz-García de la Foz, Ángel Yorca-Ruiz, Carlos Martínez-Asensi, Eva Munarriz-Cuezva, Rosa Ayesa-Arriola

“…The study enhances our understanding of MIA's impact on early development, emphasizing the importance of addressing homeostatic mechanisms in mothers and newborns.…”
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Abnormal methylation of Mill1 gene regulates osteogenic differentiation involved in various phenotypes of skeletal fluorosis in rats and methionine intervention by Niannian Chen, Jing Zhang, Congyu Yin, Yudan Liao, Lei Song, Ting Hu, Xueli Pan

“…This study offers a theoretical foundation for understanding the mechanism behind the various phenotypes of skeletal fluorosis through the perspective of DNA methylation and for employing nutrients to intervene in skeletal fluorosis.…”
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XCF-LSTMSATNet: A Classification Approach for EEG Signals Evoked by Dynamic Random Dot Stereograms by Tingting Zhang, Xu Yan, Xin Chen, Yi Mao

“…The incorporation of the self-attention mechanism further amplifies the model’s ability to grasp long-distance dependencies and enables dynamic weight allocation to the extracted features. …”
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The relationship of lamins with epigenetic factors during aging by R. N. Mustafin, E. K. Khusnutdinova

“…Identification of the epigenetic mechanisms of interaction of lamins with transposons during aging can become the basis for the development of methods of life extension and targeted therapy of age-associated cancer.…”
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The Anti-Inflammatory Effects of Shinbaro3 Is Mediated by Downregulation of the TLR4 Signalling Pathway in LPS-Stimulated RAW 264.7 Macrophages by Hwa-Jin Chung, Wonil Koh, Won Kyung Kim, Joon-Shik Shin, Jinho Lee, Sang Kook Lee, In-Hyuk Ha

“…Shinbaro3 also downregulated the mRNA and protein expression of inflammatory mediators in a dose-dependent manner. Three mechanisms explaining the effects of Shinbaro3 in RAW 264.7 cells were identified as follows: (1) inhibition of the extracellular signal-regulated kinase 1 and 2 (ERK1/2), stress-activated protein kinase (SAPK)/c-Jun N-terminal protein kinase (JNK), and p38 mitogen-activated protein kinase (MAPK) pathways; (2) suppression of IκB kinase-α/β (IKK-α/β) phosphorylation and nuclear factor-kappa B (NF-κB) subunits in the NF-κB pathway, which are involved in MyD88-dependent signalling; and (3) downregulation of IFN-β mRNA expression via inhibition of interferon regulatory factor 3 (IRF3) and Janus-activated kinase 1 (JAK1)/signal transducer and activator of transcription 1 (STAT1) phosphorylation, which is involved in TRIF-dependent signalling. …”
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Essential Roles of PKA, iNOS, CD95/CD95L, and Terminal Caspases in Suppression of Eosinopoiesis by PGE2 and Other cAMP-Elevating Agents by Bianca de Luca, Pedro Xavier-Elsas, Mônica Barradas, Ricardo A. Luz, Túlio Queto, Carla Jones, Maria Augusta Arruda, Thiago Mattar Cunha, Fernando Queiroz Cunha, Maria Ignez Gaspar-Elsas

“…In mice, eosinopoiesis is suppressed in vitro by prostaglandin E2 (PGE2) and in vivo by diethylcarbamazine, through a proapoptotic mechanism sequentially requiring inducible NO synthase (iNOS) and the ligand for death receptor CD95 (CD95L). …”
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Drilling characteristics optimization of polymer composite fortified with eggshells using box-Behnken design and zebra optimization algorithm by B. Deepanraj, A.M. Saravanan, N. Senthilkumar, Abdul Aziz Afzal, Abdul Rahman Afzal

“…With higher inclusion of ESP, the mechanical strength increases, which lowers the MRR and produces better SR. …”
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Automated Morphology Detection of Nail-Fold Capillaries Through Enhanced Object Detection Network by Hang Thi Phuong Nguyen, Hieyong Jeong

“…Our enhancements included adding a detection layer to improve the detection of various-sized objects, implementing Efficient Channel Attention (ECA) mechanisms, and incorporating data augmentation techniques and hyper-parameter tuning. …”
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RESEARCH ON DYNAMIC AND STATIC STIFFNESS CHARACTERISTICS OF MESH ELASTIC PAD by ZHAO Feng, HE ZhenXing, SHI GuangTian, CHEN QingChao, ZHOU HuaLong, WANG BinCang

“…Aiming at a new type of honeycomb mesh-type elastic cushion plate structure,a three-dimensional finite element model was established,and the mechanical properties of rubber material were simulated by super-elastic and viscoelastic constitutive models. …”
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Effect of Polymer Network Architecture on Adsorption Kinetics at Liquid–Liquid Interfaces: A Comparison Between Poly(NIPAM-co-AA) Copolymer Microgels and Interpenetrating Network M... by Galina A. Komarova, Elena Yu. Kozhunova, Rustam A. Gumerov, Igor I. Potemkin, Irina R. Nasimova

“…Understanding the adsorption features of polymer microgels with different chemical compositions and structures is crucial in studying the mechanisms of respective emulsion stabilization. Specifically, the use of stimuli-responsive particles can introduce new properties and broaden the application range of such complex systems. …”
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Multi-omics analysis in inclusion body myositis identifies mir-16 responsible for HLA overexpression by Daphne Wijnbergen, Mridul Johari, Ozan Ozisik, Peter A.C. ‘t Hoen, Friederike Ehrhart, Anaïs Baudot, Chris T. Evelo, Bjarne Udd, Marco Roos, Eleni Mina

“…Our analytical workflow can be reused as a method to study disease mechanisms involved in other diseases when multiple omics datasets are available.…”
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Role of the Neutrophil to Lymphocyte Ratio in Guillain Barré Syndrome: A Systematic Review and Meta-Analysis by Shirin Sarejloo, Shokoufeh Khanzadeh, Samaneh Hosseini, Morad Kohandel Gargari, Brandon Lucke-Wold, Seyedarad Mosalamiaghili, Pouria Azami, Sanaz Oftadehbalani, Shahram Sadeghvand

“…In addition, patients who underwent mechanical ventilation had higher levels of NLR compared to those who did not (SMD=0.93, 95%CI=0.05 to 1.82, P=0.03). …”
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Age discrimination and depression among older adults in South Korea: Moderating effects of exercise by Hyun Kang, Emily S. Ihara

“…Conclusions: Considering the rise of ageism in South Korea, regular exercise can serve as an important mechanism for combating ageism by effectively managing stress and enhancing self-resilience. …”
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A qualitative study exploring the feasibility and acceptability of computerised adaptive testing to assess and monitor children and young people’s mental health in primary care set... by Peter B Jones, Tamsin Ford, Anne-Marie Burn, Jan Stochl, Joanna Anderson, William Lan

“…Data were analysed using the Framework approach.Findings HCPs reported that Artemis-A has the potential to enhance mental health assessment and aid overburdened services by providing a quick, patient-centred assessment and monitoring mechanism. Benefits of the app include facilitating earlier intervention and appropriate referrals. …”
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Pulse-profile Modeling and Spin–Orbit Alignment in a Suzaku Sample of Accreting X-Ray Binary Pulsars by Silas G. T. Laycock, Rigel C. Cappallo, Pragati Pradhan, Dimitris M. Christodoulou, Biswajit Paul

“…This is because masses in binary systems overwhelmingly come from an orbital-mechanics formulation (Kepler’s third law), in which the dominant source of uncertainty is the inclination of the orbital plane.…”
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CRIP1 inhibits cutaneous melanoma progression through TFAM-mediated mitochondrial biogenesis by Jianqiang Wu, Lixia Chen, Peijun Wen

“…However, the biological function and underlying mechanisms of CRIP1 in melanoma progression are largely unknown. …”
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