Within-host bayesian joint modeling of longitudinal and time-to-event data of Leishmania infection. by Felix M Pabon-Rodriguez, Grant D Brown, Breanna M Scorza, Christine A Petersen

“…In addition to describing the mechanisms causing disease progression and impacting the risk of death, we also present the model's ability to predict individual trajectories of Canine Leishmaniosis (CanL) progression. …”
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Single-cell transcriptomics identify a novel macrophage population associated with bone invasion in pituitary neuroendocrine tumors by Xinzhi Wu, Xueshuai Han, Haibo Zhu, Mingxuan Li, Lei Gong, Sicheng Jing, Weiyan Xie, Zhaoqi Liu, Chuzhong Li, Yazhuo Zhang

“…This infiltration poses a significant surgical risk due to potential damage to vital nerves and arteries. However, the mechanisms underlying bone invasion caused by PitNETs remain elusive, and effective interventions for PitNET-induced bone invasion are lacking in clinical practice. …”
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Crisis Spreading Model of the Shareholding Networks of Listed Companies and Their Main Holders and Their Controllability by Yuanyuan Ma, Lingxuan Li

“…Our research provides a new reference to further exploration about the transmission mechanism of the crisis based SIR model and further research on the controllability of crisis spreading in financial markets.…”
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Causal Link between Ventricular Ectopy and Concussion by J. Patrick Neary, Jyotpal Singh, Jonathan P. Christiansen, Taylor A. Teckchandani, Kirsty L. Potter

“…More research is warranted to investigate the mechanisms for this dramatic and remarkable change in cardiac and cerebral functions and to further explore the brain-heart interaction and the intricate autonomic interaction that exists between the extrinsic and intracardiac nervous systems.…”
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STRUCTURE DESIGN AND EXPERIMENT OF MULTIPURPOSE LOWER LIMB REHABILITATION EXOSKELETON by LI Gang, WANG YuJuan, LI XueWei, DU ZhenJun, CHEN YuXi

“…Based on the design of generic size structure of legs,a two-way synchronous fast adjusting mechanism with threaded transmission was proposed to realize the function of fast adjusting the length of exoskeleton leg with one hand. …”
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Trichostatin A promotes de novo shoot regeneration from Arabidopsis root explants via a cytokinin related pathway by Su Hyun Park, Yu Jeong Jeong, Soyoung Kim, Jiyoung Lee, Cha Young Kim, Jae Cheol Jeong

“…Abstract De novo shoot regeneration, characterized by the emergence of adventitious shoots from excised or damaged tissues or organs in vitro, is regulated by the complex interplay between genetic and epigenetic regulatory mechanisms. However, the specific effect of histone deacetylation on shoot regeneration remains poorly understood. …”
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Digital technology innovation, supply chain resilience and enterprise performance-The case of listed automotive parts manufacturing companies. by Xiangbing Chen, Chen Sun, Fang Wang

“…To explore its impact mechanism on enterprise performance. The empirical results show that: (1) Digital technological innovation (DTI) has a positive and significant impact on enterprise performance, and supply chain resilience plays a mediating role in the relationship between digital technology innovation and enterprise performance, and R&D investment (RDI) positively moderates the role of supply chain resilience in promoting enterprise performance. (2) Heterogeneity analysis showed that the impact of supply chain resilience on enterprise performance was more significant in small and medium-sized enterprises. …”
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Anti-HER2 biparatopic antibody KJ015 has near-native structure, functional balanced high affinity, and synergistic efficacy with anti-PD-1 treatment in vivo by Zheng Wang, Yu Liu, Yunxia Xu, Lin Lu, Zhen Zhu, Baojie Lv, Xin Fang, Yao Tang, Jinhua Wang, Yu Cheng, Ying Hu, Junwen Lou, Peican Wu, Chendan Liu, Yanjun Liu, Xin Zeng, Qing Xu

“…BpAbs bind two independent epitopes on the same antigen, which allows fine-tuning of mechanisms of action, including enhancement of on-target specificity and induction of strong antigen clustering due to the unique binding mode. …”
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Antimicrobial Activity and Mode of Action of N-Heterocyclic Carbene Silver(I) Complexes by Giusy Castagliuolo, Michela Di Napoli, Tshering Zangmo, Joanna Szpunar, Luisa Ronga, Anna Zanfardino, Mario Varcamonti, Diego Tesauro

“…In addition, further investigations were made using fluorescence and scanning electron microscopy (SEM) in order to gain more insights into the mechanism of action. Some preliminary information on the Ag target was obtained by analyzing the cytosol of <i>E. coli</i> treated with Ag5MC by size-exclusion chromatography (SEC) coupled with inductively coupled plasma mass spectrometry (ICP-MS).…”
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Influence of welding sequences on residual stress and deformation of U-rib components fabricated by laser-arc hybrid welding by Shaoning Geng, Yuantai Li, Ping Jiang, Yilin Wang, Jun Jin, Chu Han

“…A thermo-elastic-plastic finite element model was developed to capture the complex thermal and mechanical behavior during the U-rib welding process. …”
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Aluminum-Induced Alterations in Purinergic System Parameters of BV-2 Brain Microglial Cells by Charles Elias Assmann, Vitor Bastianello Mostardeiro, Grazielle Castagna Cezimbra Weis, Karine Paula Reichert, Audrei de Oliveira Alves, Vanessa Valéria Miron, Margarete Dulce Bagatini, Taís Vidal Palma, Cinthia Melazzo de Andrade, Micheli Mainardi Pillat, Fabiano Barbosa Carvalho, Cristina Ruedell Reschke, Ivana Beatrice Mânica da Cruz, Maria Rosa Chitolina Schetinger, Vera Maria Melchiors Morsch

“…Thus, this study provides new insights into the involvement of the purinergic system in the mechanisms underlying Al toxicity in microglial cells.…”
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Multimodal neurophenomenology of advanced concentration absorption meditation: An intensively sampled case study of Jhana by Avijit Chowdhury, Marta Bianciardi, Eric Chapdelaine, Omar S. Riaz, Christopher Timmermann, Remko van Lutterveld, Terje Sparby, Matthew D. Sacchet

“…Overall, our results suggest that ACAM-J is associated with the modulation of large-scale brain networks in both fMRI and EEG, with potential implications for understanding the mechanisms of deep concentration practices and their effects on subjective experience.…”
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Effect of Silt and Clay Fraction Content on Frost Heave of Fine-Grained Soils by WITEK-ZIELONKA Kinga, PARYLAK Krzysztof, KILIAN Wojciech, ZIELONKA Łukasz

“…Therefore, an experimental attempt was made to link the graining features of the four soils with the mechanisms of the formation of frost heave. The main aim of the study is to determine the influence of the content of silt and clay fractions on the height of the frost heave. …”
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Improved constructs for bait RNA display in a bacterial three-hybrid assay by Linh D. Nguyen, Hannah LeBlanc, Katherine E. Berry

“…With these new constructs, a broader range of RNA–protein interactions are detectable in the B3H assay, expanding the utility and impact of this genetic tool as a platform to search for and interrogate mechanisms of additional RNA–protein interactions.…”
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Histological and immune response in the fish Centropomus viridis elicited by the parasite Rhabdosynochus viridisi by Dania López-Moreno, Zeinab Yazdi, Francisco N. Morales-Serna, Juan M. Martínez-Brown, Leonardo Ibarra-Castro, Alejandra García-Gasca, Selene M. Abad-Rosales, Rodolfo Lozano-Olvera, Emma J. Fajer-Ávila, Esteban Soto

“…As showed by the decrease of the intensity of infection from Time 1 to Time 2, it seems that the PWS is able to combat R. viridisi; however, our immunological analysis did not reveal strong evidence of a possible mechanism. …”
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Retrospectively understanding the multifaceted interplay of COVID-19 outbreak, air pollution, and sociodemographic factors through explainable AI by Mohmmed Talib, Kripabandhu Ghosh, Gopala Krishna Darbha

“…The primary objective centers on deploying explainable AI (XAI) methodologies to elucidate the intricate pathways and latent mechanisms governing these associations.A multi-faceted approach was employed integrating ecological study, hybrid-ML, and XAI techniques to characterize the underlying dependencies and interactions driving the pandemic's spatiotemporal evolution and system dynamics. …”
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Solar energy driven photocatalytic membrane modules for water reuse in agricultural and food industries. Pre-industrial experience using s-triazines as model molecules by Ignazio Renato Bellobono, Franca Morazzoni, Riccardo Bianchi, Emilia Simona Mangone, Rodica Stanescu, Cristina Costache, Paola Maria Tozzi

“…Quantum yields, as indicative of catalytic and photocatalytic mechanisms, were evaluated satisfactorily: they are discussed, and compared with those of previous studies on the same substrates, carried out in the same module, but in conditions of practically monochromatic irradiation (254 nm) within the range of optical absorption of semiconductor. …”
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Noggin Combined With Human Dental Pulp Stem Cells to Promote Skeletal Muscle Regeneration by Meng-Han Zhang, Li-Ming Yu, Wei-Hua Zhang, Jia-Jia Deng, Bing-Jing Sun, Mei-Hua Chen, Wei Huang, Jiao Li, Hua He, Xin-Xin Han, Yue-Hua Liu

“…However, the current myogenic induction efficiency of human DPSCs hinders their use in muscle regeneration due to the unknown induction mechanism. In this study, we treated human DPSCs with Noggin, a secreted antagonist of bone morphogenetic protein (BMP), and discovered that Noggin can effectively promote myotube formation. …”
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Pentraxin 3: a novel biomarker in pediatric central nervous system infections by Huda El-Kady, Mona Gamal Mostafa, Shaimaa Madkour

“…Patients who needed mechanical ventilation or experienced adverse outcomes had greater levels of PTX3, which were more prevalent in those with a bacterial etiology (P value < 0.05). …”
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Study of height-spread sporadic-E layers observed in the South American Magnetic Anomaly by Juliano Moro, Juliano Moro, Jiyao Xu, José Valentin Bageston, Lígia Alves da Silva, Lígia Alves da Silva, Laysa Cristina Araújo Resende, Laysa Cristina Araújo Resende, Clezio Marcos De Nardin, Vânia Fátima Andrioli, Vânia Fátima Andrioli, Angela Machado Santos, Angela Machado Santos, Giorgio Arlan da Silva Picanço, Hui Li, Liu Zhengkuan, Chi Wang, Nelson Jorge Schuch

“…Finally, the study discusses the most likely mechanisms responsible for HSEs layer formation, considering the geomagnetic conditions and time of their detection on ionograms.…”
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