Alpha Lipoic Acid Modulated High Glucose-Induced Rat Mesangial Cell Dysfunction via mTOR/p70S6K/4E-BP1 Pathway by Chuan Lv, Can Wu, Yue-hong Zhou, Ying Shao, Guan Wang, Qiu-yue Wang

“…The effect of LA on high glucose-induced cell proliferation, fibronectin (FN), and collagen type I (collagen-I) expression and its mechanisms were examined in cultured rat mesangial cells by methylthiazol tetrazolium (MTT) assay, flow cytometry, ELISA assay, and western blot, respectively. …”
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Features of interrogation of minors who are victims of violence by N. E. Miloradova, N. A. Pashko

“…It has been noted that consideration of the described psychological features during the interrogation (interviewing) of children who are victims of violence, will reduce the protective mechanisms of the psyche, minimize re-traumatization of the child and increase the effectiveness of the interrogation.…”
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Tunnel Back Analysis Based on Differential Evolution Using Stress and Displacement by Joon-Sang An, Kyung-Nam Kang, Ju-Young Choi, Won-Suh Sung, Vathna Suy, Ki-Il Song

“…Recently, the length of a segment-lined tunnel driven by the mechanized tunneling method is increasing. Because the internal displacement of a segment-lined tunnel is trivial, it is difficult to analyze the stability of segment-lined tunnels using the conventional method. …”
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Global Ionospheric TEC Forecasting for Geomagnetic Storm Time Using a Deep Learning‐Based Multi‐Model Ensemble Method by Xiaodong Ren, Pengxin Yang, Dengkui Mei, Hang Liu, Guozhen Xu, Yue Dong

“…In this study, we developed a new deep learning‐based multi‐model ensemble method (DLMEM) to forecast geomagnetic storm‐time ionospheric TEC that combines the Random Forest (RF) model, the Extreme Gradient Boosting (XGBoost) algorithm, and the Gated Recurrent Unit (GRU) network with the attention mechanism. Seven features in 170 geomagnetic storm events, including the three components Bx, By and Bz of interplanetary magnetic field (IMF), the Kp and Dst indices of geomagnetic activity data, the F10.7 index of solar activity data and global TEC data, were used for modeling. …”
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Dynamics of coagulation proteins upon ICU admission and after one year of recovery from COVID-19: a preliminary study by Raquel Behar-Lagares, Ana Virseda-Berdices, Ana Virseda-Berdices, Óscar Martínez-González, Óscar Martínez-González, Óscar Martínez-González, Rafael Blancas, Rafael Blancas, Rafael Blancas, Marcela Homez-Guzmán, Eva Manteiga, Juan Churruca-Sarasqueta, Madian Manso-Álvarez, Madian Manso-Álvarez, Madian Manso-Álvarez, Ángela Algaba, Ángela Algaba, Ángela Algaba, Salvador Resino, Salvador Resino, Amanda Fernández-Rodríguez, Amanda Fernández-Rodríguez, María A. Jiménez-Sousa, María A. Jiménez-Sousa

“…The association between coagulation protein levels and hospitalization variables was carried out by generalized linear models adjusted by the most relevant covariates.ResultsAt ICU admission, lower factor XII, antithrombin, and protein C levels were linked to the need for invasive mechanical ventilation (IMV) or its duration (p=0.028; p=0.047 and p=0.015, respectively). …”
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Association of systemic vitamin D on the course of dengue virus infection in adults: a single-centre dengue cohort study at a large institution in Singapore by Sapna P Sadarangani, Htet Lin Htun, Weiping Ling, Robert Hawkins, Tsin Wen Yeo, Laura Rivino, Paul A MacAry, Yee-Sin Leo

“…Further studies investigating the underlying immune mechanisms and effects on the vascular endothelium are needed.…”
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Altered Thyroid Function Tests Observed in Hypophosphatasia Patients Treated with Asfotase Alfa by Hajime Kato, Naoko Hidaka, Minae Koga, Yuka Kinoshita, Masaomi Nangaku, Noriko Makita, Nobuaki Ito

“…To describe thyroid function tests interfered with by asfotase alfa and elucidate the underlying mechanism. Patients and Methods. Three patients with HPP treated with asfotase alfa were included. …”
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Interleaving Carbon-Glass veil in glass epoxy composite for improved mode-I fracture toughness� A hybrid approach by Vinayak S. Uppin, P. S. Shivakumar Gouda, I. Sridhar, Aravind Muddebihal

“…Scanning electron photo images (SEPI) of cracked laminates witnessed the fracture mechanisms involved in hybrid ply interleaved and non-interleaved composite laminates…”
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Transcranial vibration stimulation at 40 Hz induced neural activity and promoted the coupling of global brain activity and cerebrospinal fluid flow by Linghan Kong, Wei Jin, Yue Jiang, Fuhua Yan, Jun Liu, Eric C. Leuthardt, Guang-Zhong Yang, Yuan Feng

“…Conventional stimulation methods such as electrical, magnetic, and ultrasound have been studied intensively, but little is known about the mechanical stimulation. Objective: To investigate the effects of 40 Hz transcranial vibration stimulation (TVS) on human brain activity, specifically focusing on changes in the Amplitude of Low-Frequency Fluctuation (ALFF), fractional ALFF (fALFF) and Regional Homogeneity (ReHo) as measures of spontaneous brain activity. …”
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Anti-proliferative and photodynamic activities of Senna didymobotrya (Fresen.) leaf alkaloid-rich extracts against breast cancer cells by Kolawole A. Olofinsan, Heidi Abrahamse, Blassan P. George

“…Conclusion Although the in silico analysis suggests that the plant-identified alkaloid phytoconstituents inhibition of estrogen receptor-alpha, human epidermal growth factor receptor-2 and progesterone receptor proteins involved in breast cancer pathogenesis could explain a possible mechanism for the observed anticancer effect, more detailed in vitro molecular experiments are necessary to confirm these findings.…”
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A fishy gut feeling – current knowledge on gut microbiota in teleosts by Ingvill Tolas, Ingvill Tolas, Zhigang Zhou, Zhen Zhang, Zhen Zhang, Tsegay Teame, Tsegay Teame, Rolf Erik Olsen, Einar Ringø, Ivar Rønnestad

“…Despite recent advances, further research is needed to elucidate species-specific mechanisms underlying GM-host interactions, the ecological implications of GM diversity, and its applications in aquaculture to optimize fish health and performance.…”
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Water phase distribution and its dependence on internal structure in soaking maize kernels: a study using low-field nuclear magnetic resonance and X-ray micro-computed tomography by Baiyan Wang, Baiyan Wang, Shenghao Gu, Juan Wang, Guangtao Wang, Xinyu Guo, Chunjiang Zhao, Chunjiang Zhao

“…The study provides a preliminary understanding of the structural basis of water distribution in maize kernels, thereby opening up the potential for designing efficient production systems and breeding cultivars well-suited for mechanical harvesting.…”
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DeepDrug as an expert guided and AI driven drug repurposing methodology for selecting the lead combination of drugs for Alzheimer’s disease by Victor O. K. Li, Yang Han, Tushar Kaistha, Qi Zhang, Jocelyn Downey, Illana Gozes, Jacqueline C. K. Lam

“…DeepDrug offers a novel AI-and-big-data, expert-guided mechanism for new drug combination discovery and drug-repurposing across AD and other neuro-degenerative diseases, with immediate clinical applications.…”
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Integrated Proteomic and Metabolomic Analysis of Muscle Atrophy Induced by Hindlimb Unloading by Yuan Wang, Xi Li, Na Li, Jiawei Du, Xiaodong Qin, Xiqing Sun, Yongchun Wang, Chengfei Li

“…However, the underlying mechanism of muscle atrophy induced by hindlimb unloading remains unclear, particularly from the perspective of the myocyte proteome and metabolism. …”
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Multiscale Attention Feature Fusion Based on Improved Transformer for Hyperspectral Image and LiDAR Data Classification by Aili Wang, Guilong Lei, Shiyu Dai, Haibin Wu, Yuji Iwahori

“…For the dual branches of hyperspectral and LiDAR, a dual-source feature interactor is designed, which facilitates interaction between hyperspectral and LiDAR features by establishing a dynamic attention mechanism, which effectively captures correlated information between the two modalities and fuses it into a unified feature representation. …”
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Efficacy and safety of Xiongzhitongluo granules in the treatment of acute ischemic stroke: study protocol for a randomized controlled trial by Yunmeng Chen, Jingjing Wei, Xiao Liang, Yue Liu, Lina Miao, Di Zhao, Yunfan Zhang, Hongxi Liu, Yunling Zhang

“…Intravenous thrombolysis and mechanical thrombectomy are essential treatments for AIS, offering substantial benefits for neurological recovery and brain protection. …”
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Gestation complications in women with metabolic syndrome: pathogenesis, diagnosis and prevention (literature review) by L.P. Shelestova, L.F. Ushullu

“…The aims of study is to analyze modern domestic and foreign studies on the study of pathogenetic mechanisms of influence of metabolic components syndrome for the development of gestational complications, methods of their diagnosis and prevention in women with metabolic syndrome. …”
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Comparative analysis of unicortical vs. subchondral locking screws in osteoporotic proximal humerus fractures by Mohammad Khak, Jeffrey J. Olson, Patrick Williamson, Mohammad Javad Shariyate, Ahmad Hedayatzadeh Razavi, Kaveh Momenzadeh, Mohammadreza Abbasian, Nadim Kheir, Edward K. Rodriguez, Ara Nazarian

“…Findings: The study found no statistically significant difference in interfragmentary displacement between the unicortical and bicortical groups (p = 0.78). The mechanical properties of both groups were found to be comparable in terms of yield (p = 0.59), ultimate (p = 0.86), and fracture strengths (p = 0.70). …”
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The prevalence of multiple organ dysfunction syndrome and its relationship with clinical variables in intensive care unit patients in Iran, 2022 by Arman Karami, Alireza Abdi, Ali Akbar Vaisi Raygani, Nader Salari, Mohammad Mehdi Mohammadi

“…Key clinical factors associated with MODS include the duration of hospitalization, ICU stay, mechanical ventilation, number of involved organs, GCS, PaO2, shock index, APACHE II, SOFA, mNUTRIC, and free water deficit. …”
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A group scheduling algorithm for massive heterogeneous data in the “dual carbon” digital intelligence monitoring center considering time-varying characteristics and priorities by Wenni Kang, Dongge Zhu, Shuang Zhang, Jia Liu, Rui Ma

“…The functional data analysis (FDA) method is used to convert the massive multi-source heterogeneous data of the “double carbon” digital intelligence monitoring center into continuous functions to solve the problem of frequency inconsistency and unify the data format; through the CNN–LSTM based on the Attention mechanism. The model extracts time-varying features from the data that eliminates heterogeneous characteristics, and implements data grouping in the “dual carbon” digital intelligence monitoring center; by setting differentiated priorities for different groups of data, it combines the data scheduling demand estimation model and delayed response time (RTT) factor and congestion factor, calculate the data priority-oriented data scheduling link similarity (DPLS), allocate the data to be scheduled to the scheduling link with the highest DPLS value for transmission, and realize the “double carbon” digital intelligence monitoring center data group scheduling. …”
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