Research Progress on Biomaterials for Spinal Cord Repair by Liao Z, Bao Q, Saijilahu, Chimedtseren C, Tumurbaatar K, Saijilafu

“…In this review, we summarize the latest progress in the treatment of SCI by biomaterials, and discussed its potential mechanism.Keywords: biomaterials, spinal cord injury, neural regeneration…”
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Water budget in flat vs. steep subduction: implication for volcanism and potential for H2 production by Gauthier Alexis, Larvet Tiphaine, Le Pourhiet Laetitia, Moretti Isabelle

“…In this study, we model the processes of (de)hydration and melting within subduction zones using a thermo-mechanical modeling approach. Multiple 2D simulations are conducted to investigate how the subduction angle influences the water budget in oceanic-continental subduction, focusing mainly on the variation of slab dip angle along the strike of the Andes. …”
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Porcine pericardial decellularized matrix bilayer patch containing adipose stem cell-derived exosomes for the treatment of diabetic wounds by Wei Liang, Huiting Wu, Lindan Tan, Xiaoyu Meng, Wanwen Dang, Meng Han, Yonghuan Zhen, Haifeng Chen, Hongsen Bi, Yang An

“…In terms of the underlying biological mechanism, we found that decellularized extracellular matrix bilayer patches loaded with ADSC-exos enhanced the proliferation and migration of human dermal fibroblasts (HDFs) and HaCaT cells in vitro, and promoted tube formation in human umbilical vein endothelial cells (HUVECs). …”
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Antioxidant, Anti-α-Glucosidase, Anti-Tyrosinase, and Anti-Acetylcholinesterase Components from Stem of <i>Rhamnus formosana</i> with Molecular Docking Study by Chia-Hsuan Tsai, Ya-Lun Liou, Sin-Min Li, Hsiang-Ruei Liao, Jih-Jung Chen

“…Further molecular docking studies revealed that there may be stronger binding mechanisms between bioactive components and target enzymes (including α-glucosidase, acetylcholinesterase, and tyrosinase) than the positive control. …”
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Study on the Forecasting of Internal Solitary Wave Propagation in the Andaman Sea Using Joint Ascending-Descending Orbit Sentinel-1A Data and Machine Learning by Zexiang Cao, Junmin Meng, Jing Wang, Lina Sun, Hao Zhang

“…A CNN-LSTM hybrid neural network model, based on multiple features and the self-attention mechanism, has been constructed by incorporating the characteristics of ISWs (ISW-Attention-CNN-LSTM Net, IACL Net), aiming to predict the propagation of ISWs in the Andaman Sea. …”
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Alcohol and cancer: the role of cytochrome P-4502E1 by Helmut K. Seitz, Bernardo Moreira, Manuela Neuman

“…Chronic alcohol consumption is a risk factor for tumours of the oral cavity, pharynx, larynx, oesophagus, liver, colorectum and the female breast. Various mechanisms contribute to alcohol-mediated carcinogenesis, including the action of cytochrome P-4502E1 (CYP2E1). …”
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The Use of Critical Levels for Determining Plant Response to Ozone in Europe and in North America by Robert C. Musselman, Allen S. Lefohn

“…Although flux-based critical levels are now being used for a limited number of agricultural crops and tree species where data are available, the use of flux-based critical levels is limited by the lack of adequate consideration and incorporation of plant internal detoxification mechanisms in flux modeling. Critical levels have not been used in North America; however, recent interest in the U.S. and Canada for using critical loads for nitrogen and sulfur has generated interest in using critical levels for O3. …”
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Real-world of Limosilactobacillus reuteri in mitigation of acute experimental colitis by Ningning Yue, Hailan Zhao, Peng Hu, Yuan Zhang, Chengmei Tian, Chen Kong, Zhiliang Mai, Longbin Huang, Qianjun Luo, Daoru Wei, Ruiyue Shi, Shaohui Tang, Yuqiang Nie, Yujie Liang, Jun Yao, Lisheng Wang, Defeng Li

“…However, the underlying mechanisms mediating microbiota-host crosstalk remain largely elusive. …”
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Trabecular meshwork ultrastructural changes in primary and secondary glaucoma by Aparna Rao, Tirupathi Rao, Nagapriya Banka, Sirisha Senthil, Saumya Jaketi

“…Amorphous deposits or vesicular bodies, seen only in steroid-induced glaucoma and XFG, suggest different mechanisms of TM damage in these glaucoma types.…”
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Epithelial to Mesenchymal Transition Relevant Subtypes with Distinct Prognosis and Responses to Chemo- or Immunotherapies in Osteosarcoma by Yang Zhou, Gai Li, Hu Li, Fuchong Lai, Pingguo Duan, Ming Cheng

“…GSEA was presented to uncover relevant molecular mechanisms. Results. Prognostic EMT genes across osteosarcoma patients were stratified into distinct subtypes, namely, subtypes A and B. …”
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Assessing the role of selenium in Minamata disease through reanalysis of historical samples by Mineshi Sakamoto, Masumi Marumoto, Koichi Haraguchi, Takashi Toyama, Yoshiro Saito, Steven J. Balogh, Chiharu Tohyama, Masaaki Nakamura

“…These findings provide important insight into the mechanism of MeHg intoxication and highlight the risks associated with MeHg-contaminated seafood, aiding efforts to protect consumers.…”
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Serum Levels of IL-1β, IL-6, TGF-β, and MMP-9 in Patients Undergoing Carotid Artery Stenting and Regulation of MMP-9 in a New In Vitro Model of THP-1 Cells Activated by Stenting by Rongrong Zhang, Fan Jiang, Cindy Si Chen, Tianzhu Wang, Jinzhou Feng, Tao Tao, Xinyue Qin

“…Second, we established a new in vitro model, where THP-1 monocytes were treated with the supernatants of human umbilical vein endothelial cells (HUVECs) that were scratched by pipette tips, which mimics monocytes activated by mechanical injury of stenting. The treatment enhanced THP-1 cell adhesion, migration and invasion ability, and the phosphorylation of ERK1/2 and Elk-1 and MMP-9 expression were significantly increased. …”
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miR-134-3p Regulates Cell Proliferation and Apoptosis by Targeting INHBA via Inhibiting the TGF-β/PI3K/AKT Pathway in Sheep Granulosa Cells by Xinai Huang, Yongjin Bao, Fan Yang, Xiaodan Li, Feng Wang, Chunxiang Zhang

“…In summary, these results add to our understanding of the molecular mechanisms involving important miRNAs in ewe fecundity by indicating that miR-134-3p influences cell proliferation, cell apoptosis, and the TGF-β/PI3K/AKT/mTOR axis, which, in turn, influences the follicular development of sheep GCs.…”
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The Predictive Significance of Platelet‐to‐Lymphocyte Ratio for Miscarriage: A Systematic Review and Meta‐Analysis by Xiaoyi Wang, Yanfang Zhao, Yangyang Fan, Yun Liu

“…ABSTRACT Background Miscarriage is a common complication of pregnancy, and its underlying pathophysiologic mechanisms remains unclear. The platelet‐to‐lymphocyte ratio (PLR), a prothrombotic and inflammatory marker, has been controversially discussed as a potential predictor of miscarriage. …”
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Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats by Hong Yang, Cheng Zhang, Woonghee Kim, Mengnan Shi, Metin Kiliclioglu, Cemil Bayram, Ismail Bolar, Özlem Özdemir Tozlu, Cem Baba, Nursena Yuksel, Serkan Yildirim, Shazia Iqbal, Jihad Sebhaoui, Ahmet Hacımuftuoglu, Matthias Uhlen, Jan Boren, Hasan Turkez, Adil Mardinoglu

“…However, the intricate mechanisms underlying these interventions remain incompletely understood given their multifaceted effects across multiple tissues. …”
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Platycodin D inhibits tumor proliferation by modulating macrophage polarization through promoting JAK2 ubiquitination by Wei Wu, Jie Zhang, Zijiao Wang, Chuan Cheng, Dongdong Yuan, Li Peng, Le Li

“…Based on this, we hypothesized that PD could have anti-melanoma potential and set out to investigate its molecular mechanisms in relation to TAMs. Treatment with PD led to a significant reduction in melanoma tumor weight, inhibition of the mTOR pathway, and suppression of M2-polarized macrophages. …”
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Maintenance of microclimate parameters in unheated parts of buildings by overflow air heating by S. V. Sarsyan, V. Yu. Kravchuk

“…The research methodology is based on the traditional laws and equations of heat and mass transfer, aerodynamics and continuum mechanics; application of I–d diagram and the rules of construction of heat and humidity air treatment; principles of operation and design of ventilation equipment; sanitary and hygienic bases of ventilation design. …”
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Review of design and manufacturing of superabsorbent polymers (SAPs) hydrogel for agriculture in arid areas by Maysa Muhammad, Medhat Tawfic, Mohamed Taha, Ahmed Elsabbagh

“…SAP materials to enhance sandy soil compactness, topology, and mechanical properties (swelling, water harvesting, and nutrient release). …”
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Cutting performance and surface integrity during rotary ultrasonic elliptical milling of cast Ni-based superalloy by Zhefei Sun, Yihang Liu, Daxi Geng, Deyuan Zhang, Enze Ying, Runze Liu, Xinggang Jiang

“…Nevertheless, their remarkable mechanical and thermal properties give rise to issues such as poor machinability and surface integrity, and severe tool wear. …”
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Seismic Response of a Bridge Pile Foundation during a Shaking Table Test by Yunxiu Dong, Zhongju Feng, Jingbin He, Huiyun Chen, Guan Jiang, Honghua Yin

“…An artificial mass model was used to determine the mechanism of the bridge pile-soil interaction, and the peak ground acceleration range of 0.15 g–0.60 g (g is gravity acceleration) was selected as the input seismic intensity. …”
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