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33021
Correlation between follicle diameter and pre-ovulatory metabolic profile in Bos grunniens
Published 2025-01-01“…IntroductionIn this study, we investigated the metabolic profiles of yak (Bos grunniens) follicles during the development period from the perspective of metabolomics, aiming to screen out the differential metabolites of yak follicles in different sizes and potential pathways during yak follicle development and to provide a basis for the study of follicle development and developmental mechanisms in the further stage of development.MethodsA total of 20 four-year-old female yaks were selected, and follicles of different sizes were collected after slaughter and divided into d < 3 mm, 3–6 mm and d > 6 mm. …”
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33022
Dry eye disease in keratoconus: etiology and medical treatment
Published 2022-05-01“…The author describes major endogenous and exogenous (inflammatory, immune/allergic, mechanical, neuropathic) factors triggering the development and association of these conditions. …”
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33023
Relationship between Mild Genu Varum and Genu Valgum with Degenerative Hip and Knee Disease: A Cadaveric Study
Published 2024-12-01“…Photographs of the femur and tibia in the standard anatomic position were measured for mechanical lateral distal femoral angle (mLDFA) and medial proximal tibial angle (MPTA), and analysis was based on deviation from the mean for each parameter. …”
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33024
Gas Expansion Energy Model and Numerical Simulation of Outburst Coal Seam under Multifield Coupling
Published 2021-01-01“…Due to the insufficient understanding of the outburst mechanism, the coal and gas outburst disasters in China are more serious. …”
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33025
Technologies for the reuse of demolition waste in the production of geopolymer-based building materials: prospects and opportunities
Published 2025-01-01“…The innovative results obtained as part of an international research project show how the use of demolition waste for the composition of geopolymer mixtures allows the reuse of large percentages of construction waste, while guaranteeing the mechanical performance of materials produced with traditional techniques, which have a high level of emissions; the production of geopolymers allows an 80% reduction in emissions compared to the production of Portland cement. …”
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33026
Effects of asiaticoside on the model of gestational diabetes mellitus in HTR-8/svneo cells via PI3K/AKT pathway
Published 2024-12-01“…This study aims to explore the effect of AS on the cell model of GDM and the action mechanism of the PI3K/AKT pathway.Methods The GDM model was established in HTR-8/Svneo cells with a high glucose (HG) medium. …”
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33027
Integrative pan-cancer analysis and experiment validation identified GLS as a biomarker in tumor progression, prognosis, immune microenvironment, and immunotherapy
Published 2025-01-01“…However, its biological roles and mechanisms in human cancers remain obscure. Consequently, the integrated pan-cancer analyses and biological experiments were conducted to elucidate its oncological functions. …”
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33028
Beyond Current Frontiers of Electrocatalysis
Published 2025-01-01“…Of critical importance for the control of the water electrolysis mechanism is understanding the origins of the electrocatalytic activity. …”
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33029
Unraveling Incongruence: The EU Proposal in the Belgrade-Pristina Dialogue
Published 2024-11-01“…While the proposal lacks formal legal bindingness, the EU wields considerable influence, applying pressure on Serbia through mechanisms such as economic sanctions. However, such measures risk exacerbating anti-EU sentiment within Serbia. …”
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33030
An Experimental Study and Mathematical Modeling of Vibration Transfer in Pistachio Trees Using an Inertia-Type Trunk Shaker and Field-Adapted Wireless Sensors
Published 2022-01-01“…Trunk shakers are the most widely used mechanical harvesting machines for harvesting nut trees, including pistachio in California. …”
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33031
Triiodothyronine activates THRβ to promote PGC1α expression alleviating PQ-induced pulmonary fibrosis
Published 2025-01-01“…The aim of this study was to examine whether there was a deficiency of TH in mouse lung tissue after PQ administration, and to explore the effect of T3, and potential mechanisms of action, in alleviation of PQ-induced pulmonary fibrosis. …”
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33032
<i>Vibrio vulnificus</i>—A Review with a Special Focus on Sepsis
Published 2025-01-01“…The bacterium thrives in warm, brackish waters with high salinity levels, and its prevalence is rising due to the effects of climate change, including warming ocean temperatures and expanding coastal habitats. …”
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33033
The auxin signaling pathway to its PIN transporters: insights based on a meta-analysis of auxin-induced transcriptomes
Published 2021-03-01“…In Arabidopsis thaliana, the PIN, ARF, and Aux/IAA families contain a larger number of members; their various combinations are possible in realization of the signaling pathway, and this is a challenge for understanding the mechanisms of this process. The use of high-throughput sequencing data on auxin-induced transcriptomes makes it possible to identify candidate genes involved in the regulation of PIN expression. …”
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33034
Leucine Modulates Mitochondrial Biogenesis and SIRT1-AMPK Signaling in C2C12 Myotubes
Published 2014-01-01“…Previous studies from this laboratory demonstrate that dietary leucine protects against high fat diet-induced mitochondrial impairments and stimulates mitochondrial biogenesis and energy partitioning from adipocytes to muscle cells through SIRT1-mediated mechanisms. Moreover, β-hydroxy-β-methyl butyrate (HMB), a metabolite of leucine, has been reported to activate AMPK synergistically with resveratrol in C2C12 myotubes. …”
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33035
Altered functional network topology properties to detect anxiety and depression caused by Crohn’s disease and disease severity
Published 2025-02-01“…Objective: Here we investigated changes in topological properties of functional brain networks among individuals with Crohn’s disease (CD) and to determine whether these changes are related to CD severity, as well as CD-associated anxiety and depression, which are regulated by the brain–gut axis mechanism. Methods: In total, 31 individuals with CD, 21 with irritable bowel syndrome (IBS), and 20 healthy controls underwent functional magnetic resonance imaging. …”
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33036
Integrated microfluidics-based construction of anti-BTN2A2 gel droplet cell preparations for non-invasive tumor-infiltrating lymphocyte therapy
Published 2025-04-01“…Specifically, the cell preparation exerted its anti-tumor effects through multiple mechanisms: Firstly, the surface BTN2A2 antibodies effectively inhibited the proliferation of Tregs and MDSCs within the tumor microenvironment; Secondly, leveraging the T cell antigen receptors (TCRs) present in the blood T cells, which were similar to those of tumor-infiltrating lymphocytes, significantly enhanced their targeting and cytotoxic capabilities; Furthermore, the CMP component within the droplets effectively promoted the infiltration of T cells into tumor tissues. …”
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33037
Anomaly detection solutions: The dynamic loss approach in VAE for manufacturing and IoT environment
Published 2025-03-01“…The innovative dynamic loss function integrates a tempering index mechanism with tuneable parameters (α and γ), which assigns higher weights to underrepresented classes and down-weights easily classified samples. …”
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33038
Enhancing surface integrity of medical Ti–6Al–4V alloy via magnetic field-assisted mass polishing
Published 2025-01-01“…Post-polishing, the mechanical properties and surface Post-polishing after MAMP, the TC4 samples do not exhibit any significant changes in elemental weight% or phase transformation when compared to the initial samples. …”
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33039
Early and Ultraearly Administration of Tranexamic Acid in Traumatic Brain Injury: Our 8-Year-Long Clinical Experience
Published 2020-01-01“…The most important result of head trauma, which can develop with a blunt or penetrating mechanism, is traumatic brain injury. Tranexamic acid (TXA) can be used safely in multiple trauma. …”
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33040
THE CURRENT STATE AND POSSIBLE SOLUTIONS OF WATER AND POWER PROBLEMS IS CENTRAL - THE ASIAN REGION
Published 2013-12-01“…It is spoken about contradictions between the states in the hydro-electric sphere, noted that the states of Central Asia, most likely, can't develop new approach to joint development of an energy potential of the region, and the mechanism of management of hydro-electric resources which would answer the political, economic and ecological goals of each state. …”
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