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32981
Identification of a Seven-lncRNA-mRNA Signature for Recurrence and Prognostic Prediction in Relapsed Acute Lymphoblastic Leukemia Based on WGCNA and LASSO Analyses
Published 2021-01-01“…These genes represent new targets to explain the mechanisms for ALL.…”
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32982
FTO effects the proliferation, invasion, and glycolytic metabolism of colon cancer by regulating PKM2
Published 2025-01-01“…The Fat mass and obesity-associated protein (FTO), a genetic variant associated with obesity, significantly impact the energetic metabolism of mechanical tumors. However, research on the function of FTO in CRC is scarce. …”
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32983
Global trends and emerging insights in BRAF and MEK inhibitor resistance in melanoma: a bibliometric analysis
Published 2025-01-01“…Keyword and co-citation analyses revealed a transition from early focus on BRAF mutations and MAPK pathway activation to recent emphasis on immunotherapy, combination therapies, and non-apoptotic cell death mechanisms like ferroptosis and pyroptosis. These trends reflect the evolving priorities and innovative approaches shaping the field of resistance to BRAF and MEK inhibitors in melanoma.ConclusionResearch on BRAF and MEK inhibitor resistance has evolved significantly. …”
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32984
The Impact of Innovative City Pilot Policy on Urban Land Green Use Efficiency: A Quasi-Natural Experiment from China
Published 2025-01-01“…This study uses panel data from 266 cities across China and applies a difference-in-differences (DID) model to evaluate the effect of the NICPP on urban land green use efficiency (ULGUE), exploring the underlying mechanisms through the lenses of industrial structure and technological innovation. …”
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32985
Young people’s proposals for tackling everyday challenges in order to improve mental health: a qualitative comparison study based on different socioeconomic neighborhoods
Published 2025-01-01“…Socioeconomic status (SES) is associated with different stressors and different stress-coping mechanisms. Many interventions target youth mental health, but few consider socioeconomic differences in the planning, implementation, or evaluation. …”
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32986
Innovative approaches for skin disease identification in machine learning: A comprehensive study
Published 2024-06-01“…Investigate the effectiveness and performance of several algorithms, such as the flexible k-nearest neighbor, the sturdy support vector machine (SVM), and the complex convolutional neural networks (CNNs), advanced techniques for automated skin disease detection encompass deep learning methods such as recurrent neural networks (RNNs) for sequential data processing, generative adversarial networks (GANs) for generating synthetic data, and attention mechanisms for focusing on relevant image regions by means of a thorough examination of the most recent studies. …”
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32987
Frontières de l’humain et technologies de genre monstrueux
Published 2019-12-01“…This article uses queer theory (Butler, Preciado, Halberstam) to analyse Dennis Cooper's The Marble Swarm, and shows how that the novel reveals the mechanisms of edification of sexual norms. In fact, Cooper's novel questions the link between gender and monster: the monster, just as gender, is exhibited as a cultural and discursive production, through the exploration of the sexual and cultural devices that produce it. …”
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32988
Therapeutic alliance in a stepped digital psychosocial intervention for breast cancer patients: findings from a multicentre randomised controlled trial
Published 2025-01-01“… Background Action mechanisms of therapeutic alliance in stepped and digital interventions remain unclear. …”
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32989
Protective Effects of Necrostatin-1 against Concanavalin A-Induced Acute Hepatic Injury in Mice
Published 2013-01-01“…This study was designed to examine the protective effects and mechanisms of Nec-1 in concanavalin A- (ConA-) induced hepatitis in mice. …”
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32990
Ambient Air Pollution and Congenital Heart Disease: Updated Evidence and Future Challenges
Published 2025-01-01“…In this literature review, we provide an overview regarding the updated evidence related to the association between maternal exposure to outdoor air pollutants and CHD occurrence, also exploring the underlying biological mechanisms from human and experimental studies. With the exception of PM, for which there is currently moderate evidence of its positive association with overall CHD risk following exposure during the periconception and throughout pregnancy, and for ozone which shows a signal of association with increased risk of pooled CHD and certain CHD subtypes in the periconceptional period, for the other pollutants, the data are inconsistent, and no conclusion can be drawn about their role in CHD onset. …”
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32991
Hypoxia lowers cell carbon and nitrogen content and accelerates sinking of a marine diatom Thalassiosira pseudonana
Published 2025-02-01“…To uncover the underlying mechanisms, the marine model diatom Thalassiosira pseudonana was cultured under three dissolved O2 levels (8.0 mg L-1, ambient O2; 4.0 mg L-1, low O2; and 1.3 mg L-1, hypoxia) to compare its growth, cell composition, and physiology between the light and dark periods. …”
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32992
The Effect of Length and Content of Fiber on Glass Fiber and Basalt Fiber-Reinforced Granite Residual Soil
Published 2022-01-01“…The reinforced samples were subjected to static impact load tests and SEM analysis to study its mechanical properties, microcharacteristics, and structure before and after reinforcement. …”
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32993
Different Dietary Proportions of Fish Oil Regulate Inflammatory Factors but Do Not Change Intestinal Tight Junction ZO-1 Expression in Ethanol-Fed Rats
Published 2017-01-01“…Only group CF57 displayed a significantly higher ZO-1 immunoreactive area compared to group C (p=0.0415). 25% or 57% fish oil substituted for dietary olive oil could prevent ethanol-induced liver damage in rats, but the mechanism might not be related to intestinal tight junction ZO-1 expression.…”
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32994
The epididymal microenvironment in Akodon cursor (Muridae, Sigmodontinae, Akodontini): The lifetime of spermatozoa from production to maturation
Published 2025-01-01“…These findings provide valuable insights into the molecular mechanisms underlying sperm maturation in this species. …”
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32995
Prevalence of Osteoporosis in Patients with Distal Radius Fracture from Low-energy Trauma: An Observational Study
Published 2025-01-01“…Methods: This observational cross-section study evaluated the prevalence of osteoporosis in patients with distal radius fracture from low-energy trauma among patients presenting to tertiary level hospital of Nepal from October 2022 to September 2023.The participants’ demographic data, mechanism of injury, BMD values and T-score values were recorded and diagnosis of osteoporosis and osteopenia was made according to WHO diagnostic criteria. …”
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32996
Isolation and Characterization of Colistin-Resistant <i>Enterobacteriaceae</i> from Foods in Two Italian Regions in the South of Italy
Published 2025-01-01“…Furthermore, 56 antimicrobial resistance genes were identified, suggesting the genetic mechanisms underlying resistance to several antibiotic classes. …”
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32997
Tumor-associated macrophage-derived exosome miR-194 confers cisplatin resistance in GC cells
Published 2025-02-01“…It aims to determine whether macrophage-derived exosomes are involved in the mechanism of cisplatin resistance, in order to identify potential methods for reversing resistance and improving patient outcomes. …”
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32998
Natural Gas Accumulation Characteristics in the Linxing Area, Ordos Basin, NW China: Revealed from the Integrated Study of Fluid Inclusions and Basin Modeling
Published 2020-01-01“…In this paper, fluid inclusion analysis and basin modeling are the main means to clarify the gas accumulation mechanism of the Upper Paleozoic in the Linxing area. …”
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32999
Music-based interventions using digital technology for individuals with acquired brain injuries: a scoping review
Published 2025-02-01“…Results demonstrated a clear evolution in intervention methodologies, with earlier research focusing on rhythmic and MIDI-based tools, while more recent studies integrated virtual reality, augmented reality, and adaptive feedback mechanisms. The findings showed significant improvements in motor functions, such as upper limb movement and gait, in most of the reviewed studies, as well as some cognitive benefits, particularly when personalized music interventions were applied. …”
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33000
Exploring proteins within the coccolith matrix
Published 2024-12-01“…Abstract Coccolithophores comprise a major component of the oceanic carbon cycle. These unicellular algae produce ornate structures made of calcium carbonate, termed coccoliths, representing ~ 50% of calcite production in the open ocean. …”
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