Study of Long-term Spectral Evolution and X-Ray and γ-Ray Correlation of Blazars Seen by HAWC by R. Alfaro, C. Alvarez, A. Andrés, J.C. Arteaga-Velázquez, D. Avila Rojas, H.A. Ayala Solares, R. Babu, E. Belmont-Moreno, A. Bernal, K.S. Caballero-Mora, T. Capistrán, A. Carramiñana, F. Carreón, S. Casanova, U. Cotti, J. Cotzomi, S. Coutiño de León, E. De la Fuente, D. Depaoli, N. Di Lalla, R. Diaz Hernandez, B.L. Dingus, M.A. DuVernois, M. Durocher, J.C. Díaz-Vélez, K. Engel, C. Espinoza, K.L. Fan, N. Fraija, S. Fraija, J.A. García-González, F. Garfias, A. Gonzalez Muñoz, M.M. González, J.A. Goodman, S. Groetsch, J.P. Harding, S. Hernández-Cadena, I. Herzog, D. Huang, F. Hueyotl-Zahuantitla, A. Iriarte, V. Joshi, S. Kaufmann, D. Kieda, A. Lara, W.H. Lee, J. Lee, H. León Vargas, J.T. Linnemann, A.L. Longinotti, G. Luis-Raya, K. Malone, O. Martinez, I. Martinez-Castellanos, J. Martínez-Castro, J.A. Matthews, P. Miranda-Romagnoli, J.A. Montes, E. Moreno, M. Mostafá, A. Nayerhoda, L. Nellen, M.U. Nisa, R. Noriega-Papaqui, N. Omodei, M. Osorio, Y. Pérez Araujo, E.G. Pérez-Pérez, C.D. Rho, D. Rosa-González, E. Ruiz-Velasco, H. Salazar, D. Salazar-Gallegos, A. Sandoval, M. Schneider, J. Serna-Franco, A.J. Smith, Y. Son, R.W. Springer, O. Tibolla, K. Tollefson, I. Torres, R. Torres-Escobedo, R. Turner, F. Ureña-Mena, E. Varela, L. Villaseñor, X. Wang, I.J. Watson, K. Whitaker, E. Willox, S. Yun-Cárcamo, H. Zhou, C. de León, HAWC collaboration, Abraham D. Falcone, Fredric Hancock

“…These findings contribute to the understanding of blazar emissions and their underlying mechanisms.…”
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Heteronemin Suppresses Lymphangiogenesis Through ARF-1 and MMP-9/VE-Cadherin/Vimentin by Hsien-Lin Chen, Yu-Chieh Su, Huang-Chi Chen, Jui-Hsin Su, Chang-Yi Wu, Shih-Wei Wang, In-Pin Lin, Chung-Yi Chen, Chien-Hsing Lee

“…Molecular docking, western blotting, flow-cytometry, MTT and ELISA were performed to investigate the mechanism of action. For in vivo approaches, the transgenic (fli1:EGFP; gata1:DsRed) zebrafish and mouse ear sponges were used. …”
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DNA methylation of ACADS promotes immunogenic cell death in hepatocellular carcinoma by Ze Qian, Yifan Jiang, Yacong Wang, Yu Li, Lin Zhang, Xiaofeng Xu, Diyu Chen

“…DNA methylation is an important mechanism for silencing ACADS in various malignancies. …”
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Bioinformation study of immune microenvironment characteristics of disulfidptosis-related subtypes in ovarian cancer and prognostic model construction by Ying Zhou, Yuhong Zhang, Yang Zhou, Yanzheng Gu, Youguo Chen, Juan Wang

“…Despite advancements in understanding DNA repair mechanisms and identifying novel therapeutic targets, additional strategies are still needed. …”
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Analysis of the spatiotemporal dynamics of grassland carbon sinks in Xinjiang via the improved CASA model by Xuewei Liu, Renping Zhang, Jing Guo, Haoen Xu, Yuhao Miao, Feifei Niu, Zhengjie Gao, Xiaming Yang, Fengqin Xiong, Jianli Zhang

“…Currently, methods for precisely calculating NPP (net primary productivity) and NEP (net ecosystem productivity) in arid grasslands are limited, and the changes in NEP and their driving mechanisms remain unclear. This study optimized LUEmax (maximum light use efficiency) and Wε (water stress coefficient) in the CASA (Carnegie–Ames–Stanford Approach) model and developed eight improved CASA model configurations. …”
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Impact of High Thermal Setting and Fluid Activities on Sandstone Compaction: A Case Study of the Baiyun Sag in the Pearl River Mouth Basin (Northern South China Sea) by Chi Li, Jinglan Luo, Caiwei Fan, Shanshan Li, Shijiu Wu, Chuan Lei, Kunpeng Song

“…The Baiyun Sag in the Pearl River Mouth Basin in the northern part of the South China Sea with high heat flows and a variable geothermal gradient is an ideal setting for studying the characteristics and mechanisms of the thermal compaction process. The characteristics of compaction and the effect of thermal fluid activities on reservoir physical properties are carried out, based on the observation and identification of sandstone thin sections under a microscope, the measurement and simulation of the temperatures and trapping pressures of fluid inclusions, and the calculation of the compaction porosity loss as well. …”
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Toward a M2M-Based Internet of Vehicles Framework for Wireless Monitoring Applications by Fei Ding, Ruoyu Su, En Tong, Dengyin Zhang, Hongbo Zhu, Mohamed Wahab Mohamed Ismail

“…Moreover, due to the lack of field experimental data, data transmission mechanisms from mobile vehicle terminals to the M2M-based platform rarely consider the proper transmission timing according to network performance and traffic conditions. …”
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Phenotypic insights into genetic risk factors for immune-related adverse events in cancer immunotherapy by Haochuan Ma, Dili Song, Haibo Zhang, Taidong Li, Xing Jin

“…We categorized these correlations and further explored potential mechanisms by which associated traits might influence irAEs through multivariate MR. …”
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Calculation of the molecular properties of five cephalosporins: cephradine, cephalexin, cefadroxil, cefprozil and ceftobiprole by Elso Manuel Cruz Cruz, Eslhey María Sánchez Domínguez

“…<strong><br />Methods:</strong> A theoretical study using quantum mechanics methods to model the structure and electronic properties of the cephalosporins listed above was conducted. …”
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Challenges and Novelties in the Treatment of Obesity in Adults. A review by Karolina Kuczapska, Marek Kurowski, Anna Gliwa, Monika Ryglewicz, Dariusz Fabian, Elżbieta Leszczyńska-Knaga, Natalia Jakubczyk, Weronika Rutkowska-Kawalec, Paweł Moczydłowski, Karolina Michalczuk

“…Additionally, bariatric surgery continues to offer great solution for severe obesity, combining restrictive and malabsorptive mechanisms for significant weight loss and metabolic benefits. …”
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Multi-trace elements-enriched functional drink accelerates gastric ulcer repair via the HGF/c-Met/STAT3 pathway by Yongnan Piao, Nuoya Wang, Mingji Jin, Jianyu Piao, Mingfeng Han, Zifei Wang, Chunhua Quan, Jishan Yin, Zhonggao Gao, Wenxiang Cui, Shuangqing Wang, Xiuquan Quan

“…In this study, we explored the reparative effects of a functional drink (FD) enriched with trace elements (TEs) on ethanol-induced gastric ulcers in rats and elucidated its underlying mechanism. Rats were administered anhydrous ethanol (5 mL/kg) orally to induce gastric ulcers and were then randomly assigned to a model, an omeprazole (OME, 20 mg/kg), FD with low-dose (FD-L), medium-dose (FD-M), high-dose (FD-H), FD without added TEs (FD without TEs), and an omeprazole+low-dose group (OME + L). …”
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Super‐Enhancer‐Driven IRF2BP2 is Activated by Master Transcription Factors and Sustains T‐ALL Cell Growth and Survival by Juanjuan Yu, Zimu Zhang, Yanling Chen, Jianwei Wang, Gen Li, Yanfang Tao, Yongping Zhang, Yang Yang, Chenyue Zhang, Tiandan Li, Jia Cheng, Tongtign Ji, Zhongling Wei, Wenjuan Wang, Fang Fang, Wei Jiang, Peipei Chu, Hongli Yin, Di Wu, Xiaolu Li, Xiaodong Wang, Jun‐Jie Fan, Shaoyan Hu, Zhen‐Hong Zhu, Shuiyan Wu, Jun Lu, Jian Pan

“…Identifying SE‐driven oncogenes in tumors and understanding their functional mechanisms is of significant importance. In this study, a previously unreported SE region is identified in T‐cell acute lymphoblastic leukemia (T‐ALL) patient samples and cell lines. …”
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The antioxidant potential of bacoside and its derivatives in Alzheimer's disease: The molecular mechanistic paths and therapeutic prospects by Dipanjan Karati, Swarupananda Mukherjee, Souvik Roy

“…In this review, the neuroprotective properties, pharmacological effectiveness, and molecular mechanism of bacoside scaffolds against AD have been discussed.…”
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NLP neural network copyright protection based on black box watermark by Long DAI, Jing ZHANG, Xuefeng FAN, Xiaoyi ZHOU

“…With the rapid development of natural language processing techniques, the use of language models in text classification and sentiment analysis has been increasing.However, language models are susceptible to piracy and redistribution by adversaries, posing a serious threat to the intellectual property of model owners.Therefore, researchers have been working on designing protection mechanisms to identify the copyright information of language models.However, existing watermarking of language models for text classification tasks cannot be associated with the owner’s identity, and they are not robust enough and cannot regenerate trigger sets.To solve these problems, a new model, namely black-box watermarking scheme for text classification tasks, was proposed.It was a scheme that can remotely and quickly verify model ownership.The copyright message and the key of the model owner were obtained through the Hash-based Message Authentication Code (HMAC), and the message digest obtained by HMAC can prevent forgery and had high security.A certain amount of text data was randomly selected from each category of the original training set and the digest was combined with the text data to construct the trigger set, then the watermark was embedded on the language model during the training process.To evaluate the performance of the proposed scheme, watermarks were embedded on three common language models on the IMDB’s movie reviews and CNews text classification datasets.The experimental results show that the accuracy of the proposed watermarking verification scheme can reach 100% without affecting the original model.Even under common attacks such as model fine-tuning and pruning, the proposed watermarking scheme shows strong robustness and resistance to forgery attacks.Meanwhile, the embedding of the watermark does not affect the convergence time of the model and has high embedding efficiency.…”
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Test-Retest Reliability of Two Computationally-Characterised Affective Bias Tasks by Alexandra C. Pike, Katrina H. T. Tan, Hoda Tromblee, Michelle Wing, Oliver J. Robinson

“…Affective biases have been shown to change with effective intervention: randomized controlled trials into these biases and the mechanisms that underpin them may allow greater understanding of how interventions can be improved and their success be maximized. …”
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Iodide Adsorption onto Three Organic–Inorganic Composite Adsorbents by Huifang Zhang, Tan Guo, Quan Li, Haining Liu, Xiushen Ye, Zhijian Wu

“…Chemical adsorption is the main mechanism for all the three adsorbents. Ca(ALG) 2 –AgCl was found to be the best adsorbent owing to its highest adsorption capacity, suitable adsorption rate and insensitivity to solution pH, temperature and co-existing NaCl.…”
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Deciphering the Transcriptional Metabolic Profile of Adipose-Derived Stem Cells During Osteogenic Differentiation and Epigenetic Drug Treatment by Giulia Gerini, Alice Traversa, Fabrizio Cece, Matteo Cassandri, Paola Pontecorvi, Simona Camero, Giulia Nannini, Enrico Romano, Francesco Marampon, Mary Anna Venneri, Simona Ceccarelli, Antonio Angeloni, Amedeo Amedei, Cinzia Marchese, Francesca Megiorni

“…However, a deeper understanding of the molecular mechanisms underlying ASC biology is crucial to identifying key regulatory pathways that influence differentiation and enhance regenerative potential. …”
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Genome-Wide Association Study for High Milk Yield in Saudi Arabian Dromedary using Whole Genome Sequencing by Faisal M. Alsubaie, Mohanad A. Ibrahim, Suheel Yousuf Wani, Ashraf Awad, Abdulwahed Fahad Alrefaei, Mikhlid H. Almutairi

“…The results of our GWAS unravel the complex genetic landscape of milk production in dromedary camels and provide a list of significant SNPs and candidate genes, providing valuable information for further investigations to understand the molecular mechanisms behind this important economic trait.…”
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An autopsy case with tubular obstruction by impacted swollen blebs due to ischemic acute kidney injury by Yukako Akiyama, Mitsuhiro Sato, Yoshio Taguma

“…Conclusion Our distinct finding of bleb formation with tubular obstruction strongly indicates that blebbing could be related to the mechanism of oliguric AKI in human, which supports the tubular obstruction theory as a contributing factor to the pathogenesis of ischemic AKI.…”
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Effects of Biostabilization on Engineering Properties of Geomaterials by Shengting Li, Chenyi Luo, Yi Yang, Lvzhen Yang, Lijian Wu, Tuo Huang, Zhuangji Wang

“…Biostabilization is a newly proposed method to improve the strength and durability of geomaterials, and it can serve as an alternative to chemical and mechanical stabilization. The objectives of this study are to perform biostabilization treatments for selected roadway construction geomaterials and to evaluate the biostabilization effects on engineering properties of the geomaterials. …”
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