A microfluidics platform for simultaneous evaluation of sensitivity and side effects of anti-cancer drugs using a three-dimensional culture method by Yuki Kobayashi, Honoka Hashizume, Sotaro Takiguchi, Jiajue Ji, Ryuji Kawano, Keiichiro Koiwai, Haru Yamamoto, Mohamed Elbadawy, Tsutomu Omatsu, Amira Abugomaa, Masahiro Kaneda, Tatsuya Usui, Kazuaki Sasaki

“…Organ-on-a-chip devices are tiny chips with interconnected wells and channels designed using a perfusion system and microfluidics to precisely mimic the in vivo physiology and mechanical forces experienced by cells in the body. …”
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COVID-19 CONSPIRACISM IN THE AGE OF POST-TRUTH by Ömer Ersin Kahraman

“…Thus, this article aims to investigate within a philosophical perspective the sociopsychological mechanisms of the propensity towards conspiracy theories in the post-truth era in relation with the lost faith in the Enlightenment project’s quest for universal truths due to the commodification and exploitation of information.…”
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Advancements related to probiotics for preventing and treating recurrent respiratory tract infections in children by Yali Zhang, Yali Zhang, Yingying Xu, Yingying Xu, Ling Hu, Ling Hu, Xiaomei Wang

“…This article provides an initial overview of the concept, classification, and mechanisms underlying probiotics. It emphasizes their beneficial effects on respiratory health by modulating intestinal microbial equilibrium, augmenting immune system functionality, and attenuating inflammatory responses. …”
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Delegitimizing, corruptive crises by Ángel R. Oquendo

“…Accordingly, one should not respond to the challenge exclusively in a technical manner, such as with the enactment of tougher laws or with the implementation of more drastic enforcement mechanisms. Nor should one take a merely motivational approach, in the sense of U.S. psychologist David McClelland, rather than that of Habermas. …”
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Quantifying Urban Sprawl and Its Driving Forces in China by Jintao Wang, Shiyou Qu, Ke Peng, Yanchao Feng

“…According to the regression analyses, the driving mechanism of urban sprawl in the eastern region relying on land finance and financial development has lost momentum for the limitation of urban construction land supply. …”
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Intraindividual variation in histone acetylation and its impact on autoimmune thyroid diseases by Emi Haga, Naoya Inoue, Yoshinori Iwatani, Yuya Arakawa, Emi Morita, Hidemi Hashimoto, Yusuke Noguchi, Yoh Hidaka, Mikio Watanabe

“…Histone acetylation, especially that of histone H3, is an epigenetic mechanism that regulates gene expression and is associated with the development of autoimmune diseases. …”
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Complexed hyaluronic acid-based nanoparticles in cancer therapy and diagnosis: Research trends by natural language processing by Abd Kakhar Umar, Patanachai K. Limpikirati, Bachtiar Rivai, Ilham Ardiansah, Sriwidodo Sriwidodo, Jittima Amie Luckanagul

“…A shift in research focuses from optimizing chemical toxicity to particular targeting tactics and precise release mechanisms is evident. These findings reflect the dynamic landscape of HA-based nanoparticle research in cancer therapy, emphasizing advancements in targeted drug delivery, therapeutic efficacy, and multimodal diagnostic approaches to improve overall patient outcomes.…”
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Paraquat poisoning from accidental ingestion leading to fatal outcome: A case report by Chao Liu, Mengya Yao, Jiangrong Ma, Shinan Nie

“…Subsequently, aggressive interventions such as hemoperfusion and continuous renal replacement therapy were initiated, yet there was a further decline in respiratory function, necessitating mechanical ventilation. The prognosis was poor, and ultimately, the family chose to withdraw care. …”
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Advanced heart failure: guideline‐directed medical therapy, diuretics, inotropes, and palliative care by Daniela Tomasoni, Julie K.K. Vishram‐Nielsen, Matteo Pagnesi, Marianna Adamo, Carlo Mario Lombardi, Finn Gustafsson, Marco Metra

“…Only a limited proportion of these patients can undergo heart transplantation or mechanical circulatory support. The purpose of this review is to summarize medical management of patients with advanced HF. …”
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HDN-DDI: a novel framework for predicting drug-drug interactions using hierarchical molecular graphs and enhanced dual-view representation learning by Jinchen Sun, Haoran Zheng

“…Furthermore, the enhanced dual-view learning method inspired by the underlying mechanisms of DDIs enables HDN-DDI to comprehensively capture both hierarchical structure and interaction information. …”
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The Influence of Repeated Drop Jump Training on Countermovement Jump Performance by Lin He, Yu-Ge Li, Chou Wu, Shun Yao, Yu Su, Guo-Dong Ma, I-Lin Wang

“…DJH50 height and DJs200 training times can improve SSC mechanism and improve athlete CMJ performance.…”
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Materiality Level in the Audit of Financial Statements and Its Impact on the Auditor's Professional Judgment by Yuliia Ostapenko

“…Considerable attention in the study was paid to the features of the regulatory regulation of the mechanism for calculating materiality at the level of financial reporting as a whole and for performing audit procedures. …”
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Experimental Study on Two-Step Concrete Corbels with Several Interface Conditions by Mohamed A. Hassan, M. Nasser Darwish, Said M. Allam, Muhammad A. Diab

“…Implanting corbels’ reinforcement is not recommended unless specific precautions and measures are assured and the embedment depth should be calculated and implemented to accommodate all expected failure mechanisms.…”
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Exogenous dopamine application ameliorates chilling injury and preserves quality of kiwifruit during cold storage by Morteza Soleimani Aghdam, Zeinab Asle-Mohammadi, Amin Ebrahimi, Farhang Razavi

“…Abstract This study investigated the mechanisms employed by exogenous dopamine application in alleviating chilling injury in kiwifruits during storage at 1 °C for 120 days. …”
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Water Model Study on Alloy Melting and Mixing in RH Refining Process by XU Zhibo, CHEN Chao, WANG Jia, LI Yihong, CAO Ruiyun, ZHAO Yansong, XUE Liqiang, FAN Jinping

“…In the actual RH refining process, after adding heavy alloy that is difficult to melt, it is essential to pay attention to the mixing mechanisms of the substances at the bottom area of the ladle.…”
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Analytical method for determining the stress-strain state of modular buildings by V. S. Shirokov, T. A. Belash, T. E. Gordeeva

“…The determination of forces in the elements of modular buildings from vertical loads can be carried out with high accuracy using well-known formulas of building mechanics. The main difficulty is the determination of dynamic effects (wind pulsation and seismic load). …”
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Do goats recognise humans cross-modally? by Marianne A. Mason, Stuart Semple, Harry H. Marshall, Alan G. McElligott

“…As domesticated animals regularly interact with humans, as well as members of their own species, we might expect mechanisms used to discriminate between conspecifics to also apply to humans. …”
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The prevention opportunities of retinopathy in diabetic patients – position paper endorsed by the Polish Lipid Association by Maciej Banach, Stanisław Surma, Grzegorz Dzida, Jacek Jóźwiak, Bogusław Okopień, Jacek Rysz, Konrad Szosland, Andrzej Grzybowski

“…In this Position Paper by the Polish Lipid Association (PoLA) we have reviewed the current stage of knowledge on possible mechanisms by which fenofibrate may contribute to retinopathy prevention, available data on safety and efficacy, to finally recommend administering fenofibrate in prevention of this dangerous diabetic complication, which significantly affects quality of life and disability-adjusted life-years (DALY). …”
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Research Progress of Methods of Initial Water Rights Allocation in River Basins by WU Dan, LIU Mengyao

“…The development of a robust and highly feasible method of initial water rights allocation in a river basin can provide important support for promoting high-quality economic development of the river basin and optimizing the layout of its industrial structure.This paper systematically reviews the methods of initial water rights allocation in river basins from four aspects:multi-objective coupling allocation methods,multi-stage coupling allocation methods with stakeholder participation,allocation methods oriented towards industrial structure optimization,and adaptive allocation methods.The results show that multi-objective coupling allocation methods focus on the coordinated reflection of multi-dimensional objectives,such as social equity,economic benefits,ecological protection,and risk control.The multi-stage coupling allocation methods with stakeholder participation concentrate on strengthening the interest interaction among water resource stakeholders and fully reflecting their interest demands.The allocation methods oriented towards industrial structure optimization center on promoting the optimization and upgrading of the industrial structures in river basins.The adaptive allocation methods highlight the improvement of the adaptability of the water resources in river basins to economic and social development.Initial water rights allocation in river basins has gradually developed from "multi-objective coupling allocation methods based on allocation principles" to "adaptive allocation methods based on allocation principles and the negotiation game mechanism".Solving the problem of adapting initial water rights to industrial structure optimization and promoting the optimization and upgrading of industrial structures and high-quality economic development will become the main lines of research on initial water rights allocation in river basins in the future.…”
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Modeling and analysis of ensemble average solvation energy and solute–solvent interfacial fluctuations by Shao Yuanzhen, Chen Zhan, Zhao Shan

“…Drawing upon principles of statistical mechanics and geometric measure theory, we rigorously demonstrate that the proposed models effectively capture EASE during the solvation process. …”
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