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32641
Pretreatment with G-CSF Could Enhance the Antifibrotic Effect of BM-MSCs on Pulmonary Fibrosis
Published 2019-01-01“…Granulocyte colony-stimulating factor (G-CSF) can promote the repair of a variety of damaged tissues, but the underlying mechanisms have not yet been fully elucidated. Bone marrow mesenchymal stem cells (BM-MSCs) play an important role in the repair of damaged tissue. …”
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32642
Association of Choline Intake with Blood Pressure and Effects of Its Microbiota-Dependent Metabolite Trimethylamine-N-Oxide on Hypertension
Published 2022-01-01“…An inverse relationship of choline intake with systolic BP was observed. The mechanism for the beneficial effect of TC might be associated with the diuretic effect of its metabolite TMAO.…”
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32643
Metabolic Activity in Human Intermuscular Adipose Tissue Directs the Response of Resident PPARγ<sup>+</sup> Macrophages to Fatty Acids
Published 2024-12-01“…Thus, future in-depth studies on IMAT-resident PPARγ<sup>+</sup> macrophage action mechanisms will elucidate the role of skeletal muscle in the pathogenesis of human metabolic dysfunction.…”
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32644
Biochemical Properties of the Acid Ectophosphatase Activity of <i>Phytomonas serpens</i> Involved in Cell Proliferation
Published 2024-12-01“…The elucidation of the molecular mechanisms involved in this process emerges as a relevant perspective, providing new strategies for controlling <i>Phytomonas</i> infection.…”
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32645
Mobility, ICT, and health: a built environment investigation of older Chinese migrants’ social isolation and loneliness
Published 2025-02-01“…Methods Using a survey of older Chinese migrants in the Greater Toronto Area (GTA) during the extended COVID-19 lockdown, we investigate how community mobility and ICT use, two mechanisms of socializing, relate to the built environment and influence loneliness (De Jong Gierveld 6-item scale), as well as mental and physical health (SF-12). …”
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32646
Application of Homogenized Load-Bearing Ring Hypothesis in Roadway Supporting
Published 2022-01-01“…In this study, an HLBR hypothesis was proposed with comprehensive consideration of mechanical properties of surrounding rock mass based on the reinforced arch theory and axial variation theory. …”
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32647
<italic>Hedyotis Diffusa</italic> Willd Increase Drugs Accumulation by Regulating Hedgehog Pathway in Drug Resistant Colorectal Cancer Cells
Published 2016-06-01“…Objective:To explore the effect and underlying mechanism of <italic>Hedyotis diffusa</italic> Willd (HDW) on drug efflux and regulation of Hedgehog (HH) signaling pathway in human colorectal cancer HCT-8/5-FU cells.Methods:HCT-8/5-FU Cells were treated with different concentrations of ethanol extract of HDW (EEHDW). …”
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32648
Cryopreserved Umbilical Cord Mesenchymal Stem Cells Show Comparable Effects to Un-Cryopreserved Cells in Treating Osteoarthritis
Published 2025-01-01“…And the conditioned medium of UC-MSCs (UC-CM) and cell freezing medium of C-MSCs (C-CFM) were collected for the mechanism study. No significant differences were found between UC-MSCs and C-MSCs in cell viability, immunophenotype, and trilineage differentiation capacity. …”
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32649
CausMatch: Causal Matching Learning With Counterfactual Preference Framework for Cross-Modal Retrieval
Published 2025-01-01“…Numerous sophisticated techniques have gained widespread adoption for harnessing attention mechanisms to facilitate cross-modal correspondence in matching tasks. …”
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32650
Social network sites (SNS) an archetype of techno-social stress: A systematic review
Published 2025-01-01“…Studies were categorized and coded using the Stressor-Strain-Outcome (SSO) model to examine demographic variations in stressor impacts and coping mechanisms. Results: The findings reveal a complex interplay of technological, behavioral-technological, and social stressors. …”
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32651
Comprehensive Insight of Neurodegenerative Diseases and The Role of Neurotoxin Agents — Glutamate
Published 2020-04-01“…Whereas non-receptor mediated oxidative toxicity involved the breakdown of the cystine/glutamate antiporter (xc - ) mechanism, which leads to the depletion of glutathione (GSH) and causes oxidative stress and cell death. …”
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32652
Bioprinted hydrogels in bone regeneration: a bibliometric analysis
Published 2025-02-01“…Our bibliometric-based visualization analysis revealed that the mechanical properties and osteogenic differentiation capacity of biomaterials have been a focal research topic over the past decade, while emerging research has also concentrated on the in vitro fabrication of stem cells for bone regeneration and osteogenic differentiation, particularly the precise application of in situ stem cell-loaded bioprinted organoids.ConclusionThis study provides an in-depth analysis of the research trajectory in the application of bioprinted hydrogels for bone regeneration. …”
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32653
Genome- and Transcriptome-Wide Characterization and Expression Analyses of bHLH Transcription Factor Family Reveal Their Relevance to Salt Stress Response in Tomato
Published 2025-01-01“…These results provide valuable information to further understand the significance and intricacy of the bHLH transcription factor family, and lay a foundation for further exploring functions and possible regulatory mechanisms of SlbHLH members in abiotic stress tolerance, which will be significant for the study of tomato stress resistance and agricultural productivity.…”
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32654
Study on Energy Dissipation Characteristics and Damage Law of Backfill under Cyclic Impact
Published 2022-01-01“…Moreover, it was found that the mechanical properties of the filling body affect the whole combined specimen, and the dynamic strength of the combined specimen with the cement-sand ratio of 1 : 4 was higher than that of the cement-sand ratio of 1 : 6. …”
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32655
Spatio-Temporal Segmented Traffic Flow Prediction with ANPRS Data Based on Improved XGBoost
Published 2021-01-01“…The early_stopping_rounds adjustment mechanism (EAM) is introduced to improve the effect of the XGBoost model. …”
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32656
Betulinic acid protects against ovarian impairment by decreasing F-2 toxin-induced oxidative stress and inflammation associated with the downregulation of p38 expression in mice
Published 2024-05-01“…In this study, the antioxidative and anti-inflammatory effects of BA and its underlying mechanism are explored in F-2 toxin-triggered mouse ovarian damage. …”
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32657
Altering the redox status of Chlamydia trachomatis directly impacts its developmental cycle progression
Published 2025-01-01“…For the first time, our study provides a mechanism of chlamydial secondary differentiation dependent on redox status.…”
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32658
Sustainable mortar with waste glass fine aggregates and pond ash as an alkali-silica reaction suppressor
Published 2025-07-01“…Hence, microstructural and chemical analyses are conducted to investigate the underlying reaction mechanisms. The strength results show that glass can replace natural sand with minimal impact on compressive strength up to 60 %, beyond which strength decreases by 11 % at 100 % glass. …”
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32659
The influence of hepatocyte growth factor on the proliferation and differentiation of stem cells
Published 2025-01-01“…Further research is needed to better understand its mechanisms and optimize targeted therapies. Combining pharmacological agents that modulate HGF/c-Met signaling with personalized treatment approaches could enhance therapeutic outcomes for cancer patients. …”
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32660
Oxytocin: co-evolution of human and domesticated animals
Published 2016-05-01“…At the behavioral level, OT facilitates intraspecific social contacts in mammals via various mechanisms ranging from the suppression of neuroendocrine stress responses to the direct OT action on neurons of socially relevant brain regions. …”
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