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32621
The Implementation of the Biopsychosocial Model: Individuals With Alcohol Use Disorder and Post‐Traumatic Stress Disorder
Published 2025-01-01“…Given that these disorders frequently coexist, we analyze mechanisms through which alcohol serves as a coping strategy for PTSD symptoms, particularly highlighting the drinking‐to‐cope self‐medication model, which suggests that alcohol use exacerbates PTSD symptoms and complicates recovery. …”
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32622
Prone versus Supine Position Ventilation in Adult Patients with Acute Respiratory Distress Syndrome: A Meta-Analysis of Randomized Controlled Trials
Published 2020-01-01“…There were no significant differences between prone and supine position ventilation on the duration of mechanical ventilation (WMD: −0.22; P = 0.883) or ICU stays (WMD: –0.39; P = 0.738). …”
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32623
Exosomal miR-543 Inhibits the Proliferation of Ovarian Cancer by Targeting IGF2
Published 2022-01-01“…We aimed to illustrate the potential function and molecular mechanism of exosomal microRNA-543 (miR-543) in the oncogenesis and development of OvCa. …”
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32624
Genetic Insights Into the Role of Cathepsins in Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis: Evidence From Mendelian Randomization Study
Published 2025-01-01“…However, our findings need to be further validated in a wider population, and future research should explore the potential mechanisms of cathepsins in these diseases in order to provide a basis for the development of new therapeutic strategies.…”
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32625
La centralité du foncier dans le régime d’accumulation du capital en Chine
Published 2017-12-01“…It is argued that the Chinese state — at both central and local level — has used the mechanism of property value enhancement as a major tool to ensure a smoother economic transition, by encouraging residential investment as a quasi exclusive saving vehicle. …”
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32626
Evaluation of the intracellular lipid-lowering effect of polyphenols extract from highland barley in HepG2 cells
Published 2024-01-01“…We also preliminary studied the lipid-lowering mechanism by Real-time fluorescent quantitative polymerase chain reaction (qPCR). …”
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32627
Hopping backward to move forward: Single-leg backward hopping can better detect decreased quadriceps strength induced by a fatigue protocol compared to forward and vertical hopping
Published 2025-12-01“…This study aimed to quantify the effect of decreased quadriceps strength induced by a fatigue protocol on hopping performance and lower limb mechanics in single-leg forward, vertical, and backward hopping. …”
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32628
ID3RSNet: cross-subject driver drowsiness detection from raw single-channel EEG with an interpretable residual shrinkage network
Published 2025-01-01“…First, a base feature extractor is employed to extract the essential features of EEG frequencies; to enhance the discriminative feature learning ability, the residual shrinkage building unit with attention mechanism is adopted to perform adaptive feature recalibration and soft threshold denoising inside the residual network is further applied to achieve automatic feature extraction. …”
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32629
The role of circadian rhythm regulator PERs in oxidative stress, immunity, and cancer development
Published 2025-01-01“…PER1 orchestrates the cooperation of the enzyme GPX1, modulating mitochondrial dynamics in sync with daily rhythms and oxidative stress, thus regulating the mechanisms managing energy substrates. PERs in innate immune cells modulate the temporal patterns of NF-κB and TNF-α activities, as well as the response to LPS-induced toxic shock, initiating inflammatory responses that escalate into chronic inflammatory conditions. …”
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32630
Nerve root magnetic stimulation regulates the synaptic plasticity of injured spinal cord by ascending sensory pathway
Published 2025-12-01“…However, our understanding of the neurophysiological mechanisms by which nerve root magnetic stimulation facilitates motor function recovery in the spinal cord is limited, and its role in neuroplasticity remains unclear. …”
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32631
Study on scour simulation and boundary condition conversion technology for a shallow foundation bridge
Published 2025-02-01“…To prevent and mitigate scouring risks, this paper investigates the riverbed scouring characteristics of shallow foundation bridges under different hydrological conditions.The study found that under high water levels and flow velocities, scour depth significantly increased.Under extreme hydrological conditions, a horseshoe vortex forms at the base of the front end of the bridge pier, causing scour pits on both sides of the upstream face of the foundation, which is the main cause of foundation voids that first appear at 2580 s with a maximum scour depth of -2.51 m and a void area of 0.5%, continuing to increase over time.Based on simulated scouring data, this study proposes a method for converting boundary conditions from a scouring model to a mechanical model. This method utilizes point cloud reverse engineering technology to generate a riverbed surface from the three-dimensional coordinate matrix of the boundary and import it into the structural analysis field. …”
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32632
In-situ composite formation of vanadium carbide in CrFeCoNiCu high-entropy alloy cladded on AISI304 stainless steel
Published 2025-03-01“…For this purpose, elemental powders of Cr, Co, Fe, Ni, and Cu together with V and C were mechanically mixed, and then by adding the proper amount of polyvinyl alcohol as a binder, a uniform paste was prepared. …”
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32633
Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism.
Published 2012-09-01“…Together, these studies suggest that MARV VP35 can both coat the backbone and cap the ends, and that for MARV, coating of the dsRNA backbone may be an essential mechanism by which dsRNA is masked from backbone-sensing immune surveillance molecules.…”
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32634
The CFTR Met 470 allele is associated with lower birth rates in fertile men from a population isolate.
Published 2010-06-01“…The fertility advantage conferred by Val470 relative to Met470 may provide a selective mechanism for these population genetic observations.…”
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32635
Exploring Hypertrophic Cardiomyopathy Biomarkers through Integrated Bioinformatics Analysis: Uncovering Novel Diagnostic Candidates
Published 2024-01-01“…In conclusion, RTN4, COL4A1, and IER3 are potential biomarkers of HCM, and protein degradation, mechanical stress, and hypoxia may be associated with the occurrence and development of HCM.…”
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32636
Experimental and Analytical Study on the Longitudinal Shear Bond Behaviour of Basalt Textile-Reinforced Concrete Composite Slab
Published 2023-11-01“…Based on the load-displacement response, failure mechanisms, maximum strain recorded in concrete/steel, load-slip characteristics, steel-concrete shear bond resistance, and the structural performances of basalt textile-reinforced concrete (BTRC) composite slabs were compared with the conventional concrete (CC) composite slabs. …”
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32637
Dynamic Responses of Outer Radiation Belt Electron Phase Space Densities to Geomagnetic Storms: A Statistical Analysis Based on Van Allen Probes Observations
Published 2024-11-01“…Improved knowledge of the storm‐time dynamics of outer radiation belt electron PSDs is valuable to in‐depth comprehension of various mechanisms responsible for the electron acceleration and loss. …”
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32638
Morphology of 137 Fast Radio Bursts Down to Microsecond Timescales from the First CHIME/FRB Baseband Catalog
Published 2025-01-01“…We measure subburst components within burst envelopes as narrow as ~23 μ s (FWHM), with 20% of the sample displaying substructures narrower than 100 μ s, offering constraints on emission mechanisms. Scattering timescales in the sample range from 30 μ s to 13 ms at 600 MHz. …”
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32639
Heightened expression of type I interferon signaling genes in CD4+ T cells from acutely HIV-1–infected women is associated with lower viral loads
Published 2025-01-01“…In HIV-1, several studies have reported that chronically infected women have significantly lower plasma viremia than men, although the exact mechanism by which this occurs has yet to be identified. …”
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32640
Effect of Al contents on the microstructure and cavitation erosion resistance of TiSiN/NiTiAlxCrCoN nanomultilayer films
Published 2025-01-01“…The microstructure and cross-sectional and surface images, mechanical and cavitation erosion properties of the prepared films were explored in detail. …”
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