The Evaluation of Thermodynamics and Environmental Impact of Waste Heat Recovery System Using Alternative Refrigerants by Aisyah Nyayu, Mukhtar Ariyadi Hifni, Ayu Putri Pratiwi Ilham, Sugiyanto, Fuadi Robith

“…The Organic Rankine Cycle (ORC) offers a promising solution for recovering this waste heat and converting it into mechanical or electrical power. This study conducts thermodynamic simulations using MATLAB to analyze ORC systems for diesel engine exhaust heat recovery, focusing on thermal efficiency, power generation potential, and environmental impact of different refrigerants, specifically R-141b, R-245fa, and R-123. …”
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Targeting tRNA‐Derived Non‐Coding RNA Alleviates Diabetes‐Induced Visual Impairment through Protecting Retinal Neurovascular Unit by Jin Yao, Wen Yao, Jun‐Ya Zhu, Yan Liu, Jin‐Hong Liu, Yu‐Ke Ji, Xi‐Shen Ni, Wan Mu, Biao Yan

“…Despite the critical impact of diabetic retinopathy, the precise mechanism underlying neurovascular coupling and effective strategies to suppress neurovascular dysfunction remain unclear. …”
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Liquidity constraints, real estate regulation, and local government debt risks by Xiao-Li Gong, Jin-Yan Lu, Xiong Xiong, Wei Zhang

“…Our findings provide important insights for countries seeking an effective real estate regulation mechanism to curb local government default risk.…”
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Recent advances in oblique plane microscopy by Kim Jeongmin

“…OPM is not only an excellent high-speed volumetric imaging platform by sweeping oblique lightsheet illumination without mechanically moving either the sample or objective lens in sample space, but also provides a solution for direct oblique plane imaging along any orientation of interest on the sample in a single shot. …”
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Radicalization and extremism of youth: Comparative case study of Palestine and Israel by Dobrucka Weronika

“…This paper examines these processes on youth in Israel and Palestine and aims to identify the mechanisms leading to them on both sides. The analysis highlights how the creation of the State of Israel in 1948 and the subsequent territorial disputes fueled by Zionist ideologies have perpetuated cycles of violence and retribution. …”
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Development and assessment of machine learning models for predicting fatigue response in AA2024 by Jagadesh Kumar Jatavallabhula, Tshepo Gaonnwe, Sibusiso Nginda, Vasudeva Rao Veeredhi

“…Stress-controlled fatigue tests were conducted, followed by fractographic analysis using a scanning electron microscope to assess failure mechanisms. It was observed that fatigue life decreases with increasing loading frequency, with failure modes transitioning from ductile at higher stress levels to a combination of brittle and ductile at lower stress levels. …”
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Chloramphenicol and gentamicin reduce the evolution of resistance to phage ΦX174 by suppressing a subset of E. coli LPS mutants. by Lavisha Parab, Jordan Romeyer Dherbey, Norma Rivera, Michael Schwarz, Jenna Gallie, Frederic Bertels

“…In addition, LPS modifications can impact antibiotic susceptibility, allowing for phage-antibiotic synergism. The evolutionary mechanism(s) behind such synergistic interactions remain largely unclear. …”
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More on search for causes of sensitization to tuberculin PPD for mammals in cattle by M. O. Baratov, P. S. Huseynova

“…Despite the large number of papers dealing with the description of proposed methods for bovine tuberculosis diagnosis and mechanisms of non-specific reaction development in diseased and healthy animals, various aspects require further study. …”
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Deoxycholic Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Exacerbates DSS-Induced Colitis through Promoting Cathepsin B Release by Shengnan Zhao, Zizhen Gong, Xixi Du, Chunyan Tian, Lingyu Wang, Jiefei Zhou, Congfeng Xu, Yingwei Chen, Wei Cai, Jin Wu

“…Here, we sought to explore the detailed molecular mechanism involved and examine the effect of S1PR2 blockage in a colitis mouse model. …”
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A computational chemistry-based approach to optimizing PD-1/PD-L1 inhibitors by Meijuan Zhai, Shiliang Ji, Haoran Hu, Yongjie Wu, Yi Shi, Ruifang Zhu, Yiguo Jiang, Yang Yang

“…IntroductionTo design effective small molecule inhibitors targeting the immune checkpoint PD-1/PD-L1 and to explore their inhibitory activity.MethodsIn this paper, a total of 69 PD-1/PD-L1 inhibitors with the same backbone were searched through opendatabases, and their docking mechanism with PD-L1 protein was investigatedby molecular docking method, and the active conformation of the inhibitors was explored. …”
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Development and application of geothermally derived silica grout for carbon-neutral soil stabilization by Taichi Terui, Toshiyuki Motohashi, Shigeo Sasahara, Shinya Inazumi

“…The formulation incorporates colloidal silica with specialty water glass, which not only improves mechanical durability, but also significantly reduces CO2 emissions compared to traditional silica-based grouts. …”
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Dendrobium chrysotoxum Lindl. Alleviates Diabetic Retinopathy by Preventing Retinal Inflammation and Tight Junction Protein Decrease by Zengyang Yu, Chenyuan Gong, Bin Lu, Li Yang, Yuchen Sheng, Lili Ji, Zhengtao Wang

“…(DC), a traditional Chinese herbal medicine, on DR and its engaged mechanism. After DC (30 or 300 mg/kg) was orally administrated, the breakdown of blood retinal barrier (BRB) in streptozotocin- (STZ-) induced diabetic rats was attenuated by DC. …”
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Punicalagin prevents obesity-related cardiac dysfunction through promoting DNA demethylation in mice by Shengjie Pei, Run Liu, Qingqing Ma, Peng Jiang, Xin He, Zhongshi Qi, Jiacheng Fang, Xu Yang, Zirui Yao, Xiaoqian Liu, Xianfeng Jing, Lei Chen, Duo Li

“…The aim of this study was to investigate whether punicalagin (PU) could prevent obesity-related cardiac dysfunction by promoting DNA demethylation, and to explore its possible mechanism. C57BL/6J mice were fed with standard diet, high-fat diet (HFD), HFD supplemented with resveratrol, low-dose PU (LPU) and high-dose PU (HPU) for 8 weeks. …”
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Effect of temperature control on tribological and corrosion properties of copper in cathodic cage plasma nitriding by Muhammad Bilal Khalid, Syed Salman Hussain, Ameeq Farooq, Muhammad Shafiq, Yasin Khan, Muhammad Shoaib

“…Untreated samples have shown abrasive wear at low temperatures, whereas adhesive wear is the predominant mechanism at high temperatures. At high temperatures, a low friction coefficient has been achieved due to smoother surfaces. …”
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Decoding the physics of observed actions in the human brain by Moritz F Wurm, Doruk Yiğit Erigüç

“…The high level of abstraction revealed by cross-decoding suggests a general neural code supporting mechanical reasoning about how entities interact with, and have effects on, each other.…”
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Challenges in safe environmental applications of biochar: identifying risks and unintended consequence by Mingying Dong, Mengyuan Jiang, Lizhi He, Zirun Zhang, Williamson Gustave, Meththika Vithanage, Nabeel Khan Niazi, Bo Chen, Xiaokai Zhang, Hailong Wang, Feng He

“…Furthermore, it provides a thorough overview of the adverse effects on animals, plants, microorganisms, and human health, elucidating the mechanisms of pollutant release, aging, and nano-effects from environmental geochemical processes involving biochar. …”
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Influence of Microscopic Effects on the Static Tensile Strength of Gray Cast Iron HT200 Specimens by L. Fan, H. B. Hu, X. S. Tang, J. J. He, W. Chen

“…Three scale transitional functions are speculated in view of the physical failure mechanisms. Two other material parameters in the model are determined from the test data. …”
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Metabolomics of related C3 and C4 Flaveria species indicate differences in the operation of photorespiration under fluctuating light by Xinyu Fu, Urte Schlüter, Kaila Smith, Andreas P. M. Weber, Berkley J. Walker

“…Abstract C3 photosynthesis can be complemented with a C4 carbon concentrating mechanism (CCM) to minimize photorespiratory losses. …”
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The Protective Effect of Low-Dose Ethanol on Myocardial Fibrosis through Downregulating the JNK Signaling Pathway in Diabetic Rats by Ying Yu, Xian-Jie Jia, Wei-ping Zhang, Ting-ting Fang, Jie Hu, Shan-Feng Ma, Qin Gao

“…To investigate the effects of low dose ethanol feeding in diabetic rats and analyze its underlying mechanisms. Methods. Male Sprague-Dawley rats were divided into 4 groups: control (Con), diabetes at 4 weeks (DM4W), diabetes at 8 weeks (DM8W), and EtOH + DM8W. …”
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Complexity of near-surface deformation and subsurface structure of the Chihshang creeping fault-line scarp, eastern Taiwan: insights from integration of geological and geophysical... by W. J. Huang, M. T. Fitrianto, C. C. Chen, P. Y. Chang, I. C. Yen, M. Le Béon, S. T. Lu

“…We found that (1) the Chihshang main fault is a contact of alluvium deposits and the mudstone of Lichi mélange, and has a dip angle of approximately 77° within the resistivity gradation zone 55 m east of the toe of the geomorphic escarpment; (2) it has a 2-year cumulative horizontal displacement of 20.7 mm northwestward and continuously creeps without seasonal variation; and (3) the active deformation on the escarpment results from a combined effect of fault creeping and slow gravity sliding of the mass which is steadily supplied by the Chihshang reserve faulting. A mechanism of faulting-relay landsliding is proposed to understand the active deformation on the escarpment. …”
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