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35401
Comparative transcriptomics reveal stage-dependent parasitic adaptations in the myxozoan Sphaerospora molnari
Published 2025-02-01“…Sphaerospora molnari offers an appealing model for stage-specific transcriptomic profiling and for identifying differentially expressed key functional gene groups related to parasite development. …”
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35402
Estimating the Cost-Effectiveness of Tumor Treating Fields (TTFields) Therapy with an Immune Checkpoint Inhibitor or Docetaxel in Metastatic Non-Small Cell Lung Cancer
Published 2025-02-01“…TTFields therapy extended mean lifetime survival, offering a clinically meaningful and economically justifiable option for patients progressing after platinum-based chemotherapy.Plain language summary: Recent clinical data from the LUNAR study has shown that Tumor Treating Fields (TTFields) therapy concomitant with immune checkpoint inhibitors (ICIs) or docetaxel improves survival in patients with metastatic non-small cell lung cancer (NSCLC) on or after platinum-based therapy. …”
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35403
Rearing mealworm larvae with wheat, barley or maize grains as main source of nutrients in unbalanced or balanced substrates
Published 2025-01-01“…The effects of the cereal offered as main nutrient source on growth performance and composition of T. molitor larvae were evaluated. …”
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35404
Silk Protein Gene Engineering and Its Applications: Recent Advances in Biomedicine Driven by Molecular Biotechnology
Published 2025-01-01“…The extensive applications of these modified silk proteins in the biomedical field have not only expanded the functionality of silk proteins but also offered new approaches to address medical challenges. …”
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35405
End-to-End Stroke Imaging Analysis Using Effective Connectivity and Interpretable Artificial Intelligence
Published 2025-01-01“…Ultimately, this representation is used within a directed graph convolutional architecture and investigated with explainable artificial intelligence (AI) tools, offering a more detailed understanding of how stroke alters communication within the brain. …”
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35406
Synthesis of polyfarnesene based on aqueous free-radical polymerization and molecular dynamics simulation of its properties
Published 2024-12-01“…"Farnesene monomer, obtained through the bio-fermentation, offered a unique long side chain structure that served as an excellent platform for the synthesis of “bottlebrush-like” polymers with exceptional thermal properties. …”
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35407
Identification of biomarkers for knee osteoarthritis through clinical data and machine learning models
Published 2025-01-01“…Moreover, the RPA model offered valuable insights to assist clinicians in refining prognostic assessments and optimizing clinical decision-making processes.…”
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35408
Risk barriers and sustainability in payment for ecosystem service implementation in smallholder forestry
Published 2024-07-01“…Agroforestry offers sustainable solutions for small-scale farmers and the environment, crucial for climate change adaptation and resilience. …”
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35409
Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease
Published 2025-02-01“…It provides a novel molecular mechanistic perspective and offers potential targets for future therapeutic strategies.Keywords: Alzheimer’s disease, single-cell RNA sequencing, microglia, ferroptosis, SLC11A1…”
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35410
Utilization of Phosphogypsum and Sediment in Subgrade Material for Pavement Construction
Published 2025-01-01“…This study provides valuable insights into the physico-chemical and physico-mechanical properties of pavement mixes incorporating PG and sediment, supporting the feasibility of using these alternative materials in sustainable subgrade material for pavement construction and offering a viable solution to mitigate waste generation while enhancing pavement performance.…”
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35411
Use of Indocyanine Green (ICG) to Assess Myocardial Perfusion and Territorial Distribution of Vein Grafts Implanted on Coronary Arteries in an Ex-vivo Porcine Model. A Potential Ad...
Published 2025-01-01“…It enables visualization of collaterals and the territory of distribution subtended by a graft offering real-time assessment and guidance on the grafting strategy.…”
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35412
Co-Delivery of Dacarbazine and miRNA 34a Combinations to Synergistically Improve Malignant Melanoma Treatments
Published 2025-01-01“…In addition, in vivo results indicated that Co-PHRD micelles can significantly inhibit tumor growth without causing significant damage to major organs.Conclusion: Co-delivery of DTIC and miRNA 34a via polypeptide micelles showed synergistic effects against MM, offering a new strategy for gene and chemotherapy.Keywords: nano micelle, DTIC, miRNA 34a, co-delivery, malignant melanoma…”
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35413
Characteristics of visual functions and their correlation with OCT-angiography of the macula in patients with small choroidal melanoma
Published 2022-11-01“…A timely diagnosis of small choroidal melanoma offers the opportunities of adequate treatment and, ultimately, improves the vital prognosis for patients with malignant tumor. …”
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35414
Synergetic effects of network interconnections in the conditions of virtual reality
Published 2021-01-01“…ORIGINALITY AND VALUE: The content of a virtual slice of network interaction of cluster formations in the conditions of virtual reality offered by the authors is revealed; the authors’ vision of its structural elements is given, as from a digital network augmented and virtual socio-economic reality; the taxonomy and categorization of terminology with the help of which it is possible to reveal the formation of network cooperation in the conditions of virtual reality and its further development are investigated; on the basis of the conducted deep theoretical and methodological analysis and the presentation of a retrospective of innovation and digital changes, a step-by-step transformation of cluster formations is shown. …”
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35415
Retrospective Analysis of the Prevalence and Risk Factors of Retinopathy of Prematurity in a Single-Center Cohort in Romania and Comparison with National and European Data
Published 2025-01-01“…The included European studies provided data on screening criteria, prevalence, and associated risk factors, offering a comprehensive perspective on screening effectiveness. …”
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35416
PRACTICAL TRAINING OF OFFICERS OF THE STATE FIRE SERVICE THROUGH GAME-BASED LEARNING
Published 2019-05-01“…The advantages of the offered methodology are the following: the possibility to design various schemes of practical training through the modular principle of their design; the development in cadets of the skills of team interaction, acquisition of professional experience by them in the process of role performance of duties of chiefs of rescue and fire fighting offices and department guards; the readiness formation to quickly adapt to new circumstances and to cope with non-standard problems in the conditions of limited time; to develop the abilities of critical thinking in young officers, to reflect own activity and to define the directions of professional growth.Practical significance. …”
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35417
Self-Management Strategies for Low Back Pain Among Horticulture Workers: Protocol for a Type II Hybrid Effectiveness-Implementation Study
Published 2025-01-01“…Given the challenges of implementing interventions for those working in small businesses, self-management offers an attractive and feasible option to address work-related risk factors and manage LBP. …”
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35418
Machine and deep learning algorithms for sentiment analysis during COVID-19: A vision to create fake news resistant society.
Published 2024-01-01“…Informal education via social media plays a crucial role in modern learning, offering self-directed and community-driven opportunities to gain knowledge, skills, and attitudes beyond traditional educational settings. …”
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35419
Exosome miR-199a-5p modulated vascular remodeling and inflammatory infiltration of Takayasu’s arteritis
Published 2025-01-01“…The decreased secretion of MMP2 may potentially prompt the intimal infiltration of inflammatory cells within the vascular wall, offering a novel therapeutic opportunity by tackling both inflammatory responses and the neointimal overgrowth associated with TAK arterial damage. …”
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35420
Country economic status is strongly associated with burn survival - validation of the (modified) ABSI
Published 2025-01-01“…This study compares burn mortality across countries with varying economic levels, as indicated by the Human Development Index (HDI), to assess if a modified ABSI (mABSI) offers enhanced predictive accuracy. Methods A retrospective study was performed, including over 90,000 patients from seven sources in five continents, including two burn registries and five referral burn centers. …”
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