Assessment of Antidepressant Activity of Ethanolic Extract of Hibiscus rosa sinensis Linn. Petals in Comparison with Fluoxetine and its Toxicity in Swiss Albino Mice: A Preclinical... by Sneha Ray, Swanand S Pathak

“…Since there are not many research studies on antidepressants derived from plants, this topic requires assessment. This approach offers a gradual and effective healing process, utilising harmless herbs and derived formulations that are also cost-effective and reliable. …”
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Multilocation Test of Prospective Composite Sticky Corn Varieties With High Production in Indonesia by null Edy, Andi Takdir Makkulawu, null Aminah, St Subaedah

“…Prospective varieties JPI-1, JPI-2 JPI-3, and JPI-4 offered the criteria for resistance to Downy mildew disease Peronosclerospora maydis, Peronosclerospora philippinensis type, Bipolaris maydis type blight, and leaf rust disease type Puccinia polysora. …”
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Understanding trends in osteoporosis drug prescribing: implications for reducing futile biomedical research by Jonathan R. Guillemot, Jonathan R. Guillemot, John W. Abraham, Anthea Tinker

“…Using the example of osteoporosis in France and England, the study aims to unravel the intricacies of medical decision-making in geriatric care, offering insights into the evolving landscape of healthcare policy and practice, which in turn can help reduce futile biomedical research.MethodsWe employed documentary analysis and semi-structured interviews. …”
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Development and assessment of a mortality risk prediction nomogram model for pneumocystis disease in ICU within 28 days by Yiru Weng, Tingting Zhou, Honghua Ye

“…Incorporating five critical factors, the nomogram offers a user-friendly, visual method for calculating personalized risk scores based on patient-specific information, including medical history, laboratory results, and clinical scores. …”
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Grid-Based Characterization and Sustainable Planning for Fractured Urban Textures: A Case Study of Nanhao Village in Baotou by Haoyu Tian, Weidong Wang, Ting Hao

“…This study introduces a new framework for analyzing urban texture, offering a detailed multi-faceted analysis of FUT-UV fragmentation and clarifying the interaction between FUT-UVs and surrounding urban forms. …”
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Spermine driven water deficit tolerance in early growth phases of sweet corn genotypes under hydroponic cultivation by Tahoora Batool Zargar, Mawia Sobh, Oqba Basal, Tibor Janda, Magda Pál, Szilvia Veres

“…These results highlight the potential of Spermine as an effective strategy to improve sweet corn resilience under water-limited conditions, offering a novel approach for sustainable crop management.…”
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Developing a youth-friendly internet-enabled HIV risk calculator: A collaborative approach with young key populations, living in Soweto, South Africa. by Mamakiri Mulaudzi, Gugulethu Tshabalala, Stefanie Hornschuh, Kofi Ebenezer Okyere-Dede, Minjue Wu, Oluwatobi Ifeloluwa Ariyo, Janan J Dietrich

“…They indicated a preference for an easy-to-use, interactive, real-time assessment offering discrete and private means to self-assess HIV risk. …”
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Health promotion campaigns using social media: association rules mining and co-occurrence network analysis of Twitter hashtags by Atousa Ghahramani, Maria Prokofieva, Maximilian Pangratius de Courten

“…The study contributes to knowledge and practice by offering a structured and data-driven approach and providing practical guidance for public health practitioners, professionals, and organisations to optimise content, targeting, and messaging to reach and engage a broader audience with health-related information.…”
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Unresectable Hepatic Metastasis of Uveal Melanoma: Hepatic Chemosaturation with High-Dose Melphalan—Long-Term Overall Survival Negatively Correlates with Tumor Burden by R. Brüning, M. Tiede, M. Schneider, P. Wohlmuth, H. Weilert, K. Oldhafer, A. Stang

“…PHP-M for nonresectable LMUV provides a safe and locally efficient liver-directed procedure that offers patients a chance for long-term OS, especially for patients with a low hepatic tumor burden.…”
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Safety, Tolerability and Pharmacokinetic-Pharmacodynamic Relationship of NX210c Peptide in Healthy Elderly Volunteers: Randomized, Placebo-Controlled, Double-Blind, Multiple Ascend... by Annette Janus, Daniël Dumas, Juliette Le Douce, Sébastien Marie, Giuseppe Pasculli, Pauline Bambury, Sighild Lemarchant, Philip Kremer, Yann Godfrin

“…The effects of NX210c on claudin-5 and biomarkers influencing BBB integrity—and the overarching brain protection it offers—provide a novel therapeutic strategy targeting an underlying driver of neurodegenerative conditions for which disease-modifying treatments are limited or not available.…”
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Slight thermal stress exerts genetic diversity selection at coral (Acropora digitifera) larval stages by Cristiana Manullang, Nozomi Hanahara, Ariyo Imanuel Tarigan, Yuko Abe, Mao Furukawa, Masaya Morita

“…This study uses individual larval sequencing to investigate genotype-specific responses to heat stress and the selective pressures shaping their genomes, offering finer resolution and deeper insights. Results This study investigates the larval response to heat stress before acquiring symbiotic algae, aiming to elucidate the relationship between coral genetic diversity and heat stress. …”
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Implementing sustainable practices to combat root knot nematode infestation in tomato farming from Meghalaya by H. Jeevan, Raghubir Kumar Patidar, Veronica Kadam, Pranab Dutta, Euphema Nongbri, M. N. Rudra Gouda, Santosh Naik, N. S Nysanth

“…These results indicate that combining NM, Tz, Pl and LG provide effective nematode control without phytotoxic effects, enhancing plant growth and offering a promising sustainable alternative to chemical nematicides.…”
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Evaluation of de novo donor specific antibodies after kidney transplantation in the era of donor-derived cell-free DNA by Yuan Tian, Lukas Frischknecht, Anna Mallone, Fabian Rössler, Thomas Schachtner, Jakob Nilsson

“…Integrated monitoring of dnDSA and dd-cfDNA offers a promising non-invasive approach for assessing graft injury and alloimmunity, potentially enhancing post-transplant care.…”
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Primary dysmenorrhea: pathophysiology, improvement of diagnostic and treatment possibilities by T.V. Fartushok, N.V. Fartushok

“…In view of safety and high therapeutic efficiency, the drug based on Vitex agnus castus can be offered for the treatment over the period lasting at least for3 months for girls and young women aged 13 to 45 years with primary dysmenorrhea.…”
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CircHIPK2 recruits SRSF1 to increase TXNIP mRNA stability and promotes autophagy-dependent ferroptosis and apoptosis in myocardial ischemia-reperfusion injury by Zhu Zhang, Jinqi Hao, Qinghong Qiao, Junting Song, Yanqin Yu

“…Conclusion Our results demonstrate that circHIPK2 contributes to MIRI through inducing oxidative stress and autophagy-dependent ferroptosis via SRSF1/TXNIP axis, offering new insights into MIRI treatment.…”
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Digital 3D reconstructions of synagogues for an innovative approach on Jewish architectural heritage in East Central Europe by Jan Lutteroth, Piotr Kuroczyński, Igor Piotr Bajena

“…The Ashmyany synagogue case study demonstrates how 3D reconstructions can help visualize lost architectural heritage, offering new insights into its historical context and emphasizing the need for continued research on open repositories and digital preservation efforts. …”
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ANAPUS GYVENIMO IR MIRTIES DUALIZMO: BUDISTINĖ EGZISTENCIJOS INTERPRETACIJA by Agnė Budriūnaitė

“…To accept death as intrinsic essence of life (death-in-life) and live with the existential anxiety; or to measure life and death by dimensions of eternity and to look forward to eternal life without fear of death (life-in-death). The buddhism offers another way of thinking by equalizing life and death and showing the illusiveness of ‘Self’. …”
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Prevalence of HIV infection and uptake of HIV/AIDs services among fishermen on the shores of Lake Victoria in Kagera region, Northwestern Tanzania. by Patrick Mwanahapa, Mtoro J Mtoro, Dina Gerald, Pius Horumpende, Salaam Mujeeb

“…Information was collected using an interviewer-administered questionnaire, and HIV testing was offered on-site according to national testing guidelines. …”
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A techno-economic perspective on efficient hybrid renewable energy solutions in Douala, Cameroon’s grid-connected systems by Reagan Jean Jacques Molu, Serge Raoul Dzonde Naoussi, Mohit Bajaj, Patrice Wira, Wulfran Fendzi Mbasso, Barun K. Das, Milkias Berhanu Tuka, Arvind R. Singh

“…By employing advanced simulation techniques, especially the Hybrid Optimization Model for Electric Renewable (HOMER) Pro program, the study carefully examines the intricacies of load demands across distinct consumer categories while accommodating varied pricing models. The paper offers a detailed analysis of the proposed grid-connected PV/Diesel/Generator system, aiming to gauge its performance, economic feasibility, and reliability in ensuring uninterrupted energy supply. …”
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A service ecosystems perspective to explore social prescribing value co-creation for vulnerable young people in NEET situation by Isabel Farina, Daniela Sangiorgi, Cristina Masella, Ilaria Simonelli, Regina Alves, Maria J. Marques, Sonia Dias, Carina Dantas, Sabrina Herzog, Sara Paternoster, Emanuele Torri, Marcello Bertotti

“…The service ecosystem perspective offers a valuable framework for examining the dynamic interactions between actors and understanding how their resource integration processes and institutional arrangements foster the emergence of opportunities to support an invisible and hard-to-reach target group, such as young people in NEET situations.…”
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