CASP5 associated with PANoptosis promotes tumorigenesis and progression of clear cell renal cell carcinoma by Kangkang Yang, Yushuang Wang, Yuli Jian, Bo Wang, Hao Du, Yuqing Xia, Jianlei Bi, Meihua Guo, Zhi Li, Ning Wang

“…Together, the innovative risk model using PANoptosis-associated genes effectively forecasts the tumor microenvironment and survival rates for ccRCC, offering a novel approach to the early, precise diagnosis of ccRCC and the advancement of personalized treatment strategies.…”
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An LJDRNN-based efficient energy intensity prediction in carbon fiber composite material manufacturing process by Rangaswamy Nikhil, Karthikeyan A G, Prabhu Loganathan, Tabrej Khan, Tamer A Sebaey

“…This study is of high significance to CF producers, offering a robust tool to predict and manage energy consumption effectively. …”
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Large-Scale Cross-Cultural Tourism Analytics: Integrating Transformer-Based Text Mining and Network Analysis by Dian Puteri Ramadhani, Andry Alamsyah, Mochamad Yudha Febrianta, Muhammad Nadhif Fajriananda, Mahira Shafiya Nada, Fathiyyah Hasanah

“…The findings provide insights for destination management, marketing strategies, and policy development, highlighting the importance of tailoring tourism offerings to meet the diverse preferences of visitors from different global regions.…”
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Neuroeconomically dissociable forms of mental accounting are altered in a mouse model of diabetes by Chinonso A. Nwakama, Romain Durand-de Cuttoli, Zainab M. Oketokoun, Samantha O. Brown, Jillian E. Haller, Adriana Méndez, Mohammad Jodeiri Farshbaf, Y. Zoe Cho, Sanjana Ahmed, Sophia Leng, Jessica L. Ables, Brian M. Sweis

“…Mice made self-paced choices on a daily limited time-budget, accepting or rejecting reward offers based on cost (delays cued by tone pitch) and subjective value (flavors), in a closed-economy system tested across months. …”
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Moderate stability of risk and ambiguity attitudes across quantitative and qualitative decisions by Ohad Dan, Chelsea Y. Xu, Ruonan Jia, Emily K. Wertheimer, Megha Chawla, Galit Fuhrmann Alpert, Terri Fried, Ifat Levy

“…We designed an online decision-making task where participants made binary choices between alternatives offering either guaranteed low outcomes or potentially better outcomes that were associated with some uncertainty. …”
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Development and Characterization of Mikania, Kapok, Wool, Sugarcane, and Pineapple Fiber Reinforced Polyester Composite by Rafid Anan, Hasan Al Mahmud, Tabriz Ahnaf Khan, Md Sakib Ul Alam Sakib, Md Shahadhat Hossain

“…The kapok provided an impact toughness of 1.2 N m, which was somewhat elevated. This research offers a precious understanding of using natural fibers as strengthening additives in polyester composites, demonstrating their flexible perspective for many uses. …”
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Performance Evaluation and Microstructure Study of Pervious Concrete Prepared from Various Solid Waste Admixtures by Yi Li, Jiong Zhang, Jie Ding, Feng-zhen Chen, Ming-zhu Liu, Jia Liu, Zhao Hou

“…Pervious concrete (PC) is a green infrastructure material that offers advantages such as reducing surface runoff and purifying water quality, making it an important component of sponge cities. …”
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Metagenomic exploration and computational prediction of novel enzymes for polyethylene terephthalate degradation by Donya Afshar Jahanshahi, Mohammad Reza Rezaei Barzani, Mohammad Bahram, Shohreh Ariaeenejad, Kaveh Kavousi

“…Polyethylene terephthalate (PET), one of the most commonly used plastics, has contributed significantly to this growing crisis. This study offers a solution for plastic pollution by identifying novel PET-degrading enzymes. …”
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Laccase/caffeic acid-catalyzed crosslinking coupled with galactomannan alters the conformational structure of ovalbumin and alleviates Th2-mediated allergic asthma by Ishfaq Ahmed, Suidong Ouyang, Shengquan Wu, Haochang Song, Miaoyuan Zhang, Renxing Luo, Peishan Lu, Jiaqi Deng, Tingting Zheng, Yanyan Wang, Xinguang Liu, Gonghua Huang

“…The knowledge obtained in the present study offers an effective way to acquire a hypoallergenic OVA product that can have a therapeutic effect in alleviating OVA-induced allergic asthma.…”
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pH‐Dependent Assembly and Stability of Toll‐Like Receptor 3/dsRNA Signaling Complex: Insights from Constant pH Molecular Dynamics and Metadynamics Simulations by Penghui Li, Mingsong Shi, Yibo Wang, Qiong Liu, Xiubo Du, Xiaohui Wang

“…Notably, the aromatic residue Phe84, located within the dsRNA binding site [His39⁺–His60⁺–Phe84–His108⁺], alters the pKa of His60 through cation‐π interactions with its protonated state. This study offers new insights into the molecular mechanisms underlying pH‐dependent immune signaling via higher‐order assemblies and suggests potential applications for histidine in self‐assembling biomaterials.…”
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Lightweight AES Design for IoT Applications: Optimizations in FPGA and ASIC With DFA Countermeasure Strategies by Salman Ahmed, Nabihah Ahmad, Nasir Ali Shah, Ghulam E. Mustafa Abro, Ardhi Wijayanto, Abdinasir Hirsi, Abdul Rehman Altaf

“…The Advanced Encryption Standard (AES) remains the benchmark for securing IoT systems while balancing low power consumption, minimal area usage, and moderate throughput with high security. This paper offers a comprehensive review of the latest lightweight AES architectural designs, including optimizations to the Substitution Box (S-Box), Sub-Bytes, Shift Rows, Mix Columns, and Add Round Key steps, assessing their impact on gate count, area, maximum frequency, power consumption, and throughput in field programable gate arrays (FPGA) and Application-specific integrated circuit (ASIC) implementations. …”
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A rapid method for the preparation of an in vitro osteoporosis model of calf vertebrae: histological and biomechanical study by Anli Shi, Anli Shi, Yijie Liu, Qiang Ma, Jiaxin Li, Jiawang Fan, Zhaohui Ge, Zhaohui Ge

“…The modulus of elasticity, yield stress, and ultimate stress of the vertebral bodies were all reduced in correlation with the decrease in bone mineral density, demonstrating a strong correlation between these parameters.InterpretationThe data from this study indicate that the decalcification method is effective and capable of rapidly establishing an osteoporotic model suitable for biomechanical testing of clinical devices. This method offers the benefits of ease of operation, reliability, and a controllable degree of osteoporosis.…”
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Spinal Cord Stimulation for Refractory Angina Pectoris: Current Status and Future Perspectives, a Narrative Review by Roberto Gazzeri, Jacopo Mosca, Felice Occhigrossi, Marco Mercieri, Marcelo Galarza, Matteo Luigi Giuseppe Leoni

“…Spinal cord stimulation (SCS) has emerged as a promising therapeutic option for managing RAP, offering significant symptom relief and improved quality of life. …”
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Photon-counting-detector CT outperforms state-of-the-art cone-beam and energy-integrated-detector CT in delineation of dental root canals by Stephan Rau, Martin Peter Pichotka, Alexander Rau, Marco Reisert, Markus Jörg Altenburger, Rainer Schmelzeisen, Fabian Cieplik, Fabian Bamberg, Maximilian Frederik Russe, Wiebke Semper-Hogg

“…PCD-CT provided superior resolution, accurate size measurement, and enhanced detection of small dental root canals, thereby offering improvements in diagnostic capabilities compared to CBCT and EID-CT systems.…”
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Deep-Sea-Derived Isobisvertinol Targets TLR4 to Exhibit Neuroprotective Activity via Anti-Inflammatory and Ferroptosis-Inhibitory Effects by Zi-Han Xu, Ming-Min Xie, Chun-Lan Xie, Xian-Wen Yang, Jun-Song Wang

“…Compounds derived from deep-sea fungi exhibit low toxicity and potent neuroprotective effects, offering a promising source for drug development. In this study, we isolated 44 natural products from deep-sea-derived fungi and identified isobisvertinol (<b>17</b>) as a compound with anti-inflammatory and ferroptosis-inhibiting effects. …”
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Talleres integradores interdisciplinarios en el tratamiento de los contenidos básicos biomédicos y clínicos. by Carlos Manuel Mora Hernández, Luis Alberto Mass Sosa, Ana Margarita López Rodríguez del Rey, Ada Sánchez Lozano, Anais Leiva Madrigal

“…El presente artículo tiene como objetivo ofrecer valoraciones acerca del papel de los talleres integradores interdisciplinarios en el tratamiento de los contenidos básicos biomédicos y clínicos. …”
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Las rutas del vino como motores de dinamización socio-territorial: el caso de Castilla y León by Julio Fernández Portela, María Jesús Vidal Domínguez

“…Para ello se apoya en el entramado que se genera en torno al vino, que, además, va a aprovechar el resto de potencialidades presentes en el espacio para ofrecer un producto turístico diversificado y para todo tipo de públicos. …”
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Social media activism and women's health: Endometriosis awareness and support by Hyunjin Seo, K. Macy Burkett, Moses Okocha, Huong Ha, Rim Chaif, Nazra Izhar, Michaella Barros Coelho, Blessing Jona, Azhar Iqbal

“…Conclusion People with endometriosis use Instagram to create an online public sphere for raising awareness of the disease, offering networking and support to other endometriosis patients, and creating a movement for enhancing women's health and wellness. …”
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Osteopontin as a Biomarker for Coronary Artery Disease by Georgia R. Layton, Ibrahim Antoun, Alice Copperwheat, Zaidhan Latif Khan, Sanjay S. Bhandari, Riyaz Somani, André Ng, Mustafa Zakkar

“…It is hypothesised that plasma levels of OPN may correlate with the presence of coronary artery disease, “CAD”. This offers potential as a point-of-care testing biomarker for early diagnosis, disease monitoring, and prognosis. …”
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First evidence of the effectiveness of a field application of RNAi technology in reducing infestation of the mite Varroa destructor in the western honey bee (Apis mellifera) by Francesca Bortolin, Emanuele Rigato, Sergio Perandin, Anna Granato, Laura Zulian, Caterina Millino, Beniamina Pacchioni, Franco Mutinelli, Giuseppe Fusco

“…This study supports the potential of RNAi as a promising alternative to chemical pesticides, offering a targeted, efficient and sustainable solution for managing V. destructor in honey bee populations. …”
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