Changes in DNA methylation profile in liver tissue during progression of HCV-induced fibrosis to hepatocellular carcinoma by I. A. Goncharova, A. A. Zarubin, N. P. Babushkina, I. A. Koroleva, M. S. Nazarenko

“…In this study we compared methylation levels of 27,578 CpG sites between paired samples of the tumor and surrounding liver tissues with various degrees of damage (fibrosis, cirrhosis) in HCV-induced hepatocellular carcinoma (HCC) patients, as well as between tumor and normal tissue in non-viral HCC patients, using GSE73003 and GSE37988 data from GEODataSets (https://www.ncbi.nlm.nih.gov/). …”
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Oxidative Stress, Antioxidant Capacity, and Inflammatory Markers in Patients with Idiopathic Complete Heart Block by Shobhit Shah, Monika Bhandari, Pravesh Vishwakarma, Wahid Ali, Mohammad Kaleem Ahmad, Abhishek Singh, Ayush Shukla, Akhil Kumar Sharma, Gaurav Chaudhary, Akshyaya Pradhan, Sharad Chandra, Rishi Sethi, S. K. Dwivedi

“…High significant increases in MDA (P ≤ 0.001) were indicative of increased reactive oxygen species-mediated tissue damage. Serum IL-5 (pg/ml) has a mean value of 67.347 ± 20.445 (P < 0.001) in controls and 481.442 ± 28.8995 in patients. …”
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The Malayan Landscape Paintings by Sarena Abdullah, Yuen Beng Lee

“…Ini boleh dilihat sebagai bagaimana pameran seni dan institusi, menggalakkan pembuatan seni tertentu secara predominan yang lanskap indah dan damai, dan penggambaran yang mencipta rasa ketenangan dan kedamaian di tengah-tengah cuaca darurat yang bergejolak bertujuan untuk mengurangkan kegelisahan dan memberikan ketenangan kepada orang awam. …”
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miR-26a-5p Attenuates Oxidative Stress and Inflammation in Diabetic Retinopathy through the USP14/NF-κB Signaling Pathway by Jie Bian, Weizhong Ge, Zhengmei Jiang

“…HG stimulation contributed to Müller cell dysfunction by inducing inflammation, oxidative injury, and mitochondrial damage to Müller cells. miR-26a-5p was downregulated in Müller cells under HG condition, and overexpression of miR-26a-5p relieved HG-induced Müller cell dysfunction. …”
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The Malayan Landscape Paintings by Sarena Abdullah, Yuen Beng Lee

“…Ini boleh dilihat sebagai bagaimana pameran seni dan institusi, menggalakkan pembuatan seni tertentu secara predominan yang lanskap indah dan damai, dan penggambaran yang mencipta rasa ketenangan dan kedamaian di tengah-tengah cuaca darurat yang bergejolak bertujuan untuk mengurangkan kegelisahan dan memberikan ketenangan kepada orang awam. …”
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A novel arterial coupler with non-return snap-fit connection approach optimized arterial end-to-end anastomotic technique: An experimental study by Hong-Bo Guo, Mo-Fei Wang, Ren-Qi Yin, Kang-Kang Zhi

“…A dedicated device is needed for creating arterial anastomosis in an easy, timesaving, less damaging but reliable procedure. Therefore, we plan to develop a novel arterial coupler device and test pre-clinical safety and effectiveness. …”
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Metodología de análisis y diseño de lechos de frenado Methodology for assessement and design of arrestor beds by Tomás Echaveguren, Sergio Vargas, Juan Ñancufíl

“…To mitigate the potential damage, exist several systems that permits heavy vehicles leave the lane and stop. …”
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A Case Study Identified a New Mutation in the TTN Gene for Inherited Hypertrophic Cardiomyopathy by Dong J, Liu M, Chen Q, Zha L

“…In addition, this mutation was predicted to damage protein function. WES combined with Sanger sequencing results showed that the other two HCM patients in this family carried this TTN mutation, while none of the healthy family members carried the mutation except for a 3 years old girl.Conclusion: In this study, a new pathogenic mutation of TTN was found in a Chinese family with HCM, and disease-causing gene carriers in the family members were identified through pedigree screening. …”
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Pengaruh Pemberian Gel Lidah Buaya (Aloe vera) Terhadap Jarak Pinggir Luka pada Tikus Wistar by Farhan Nazir, Asril Zahari, Eliza Anas

“…<br />Kata kunci:  gel lidah buaya, penyembuhan luka, jarak pinggir luka<br /><br />Abstract <br />A wound is a laceration or break in the living tissue which causes continuity damage within the tissue. Aloe vera has been used for traditional medication in many cultures all over the world. …”
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Interplay between oxidative stress, neuroinflammatory cytokines and melatonin in Alzheimer's disease: Insights from cerebrospinal fluid analysis by Francisco Artime-Naveda, David Hevia, Rebeca Alonso-Arias, Carmen Martínez, Isabel Quirós-González, Rafael Cernuda-Cernuda, Alejando Alvarez-Artime, Iván Menéndez-Valle, Rosa M. Sainz, Juan C. Mayo

“…Results: Correlational and group analysis showed a positive association between oxidative stress and neuronal damage. TNF-α negatively correlated with CSF Aβ levels (amyloid plaques) while only RANTES/CCL5 correlated positively with T-tau and P-tau. …”
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Electroacupuncture Relieves Suppression of Autophagy in Interstitial Cells of Cajal of Diabetic Gastroparesis Rats by Xing Wei, Yaping Lin, Dongfeng Zhao, Xiaojuan Xiao, Qiao Chen, Siyi Chen, Yan Peng

“…Autophagy could degrade damaged proteins and organelles to keep intracellular homeostasis, and it could directly influence structure and number of cells. …”
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CO2 field-flooding devices offer potential value for cardiopulmonary bypass procedures for CHD performed via a right-side small incision approach by Zhangke Guo, Zhimin Li, Song Bai, Feng Tong, Jia Zheng, Nan Ding, Xiaofeng Li

“…Demographic, perioperative, arterial blood gas (ABG), and laboratory test data were then compared between these groups of patients. …”
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First Aid Education Guidelines for Peer Learning: The Approach in Practice

“…El aprendizaje entre iguales puede ser muy eficaz para garantizar que los conocimientos y las habilidades que se exploran en la educación de primeros auxilios se adaptan, se contextualizan y se aplican localmente. Además, la humildad es un rasgo importante para el facilitador, ya que debe sentirse cómodo en lo desconocido. …”
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COVID-19 – if the cure is worse than the disease. The Italian chaos by Giuseppe FERRARI

“…The most alarming data out of Italy is the number of deaths which, at time of writing, is more than 20,000. …”

Explanation and validation of the coordination model of the marketing and sales department in the insurance industry in Iran by Alireza Jahed, Ehsan Abedi, Hamidreza Saeednia

“…In this descriptive survey study, 165 managers and supervisors of the central headquarters, branches and representative offices of Dana Insurance in Mashhad were selected by a simple random method. …”
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Designing an entrepreneurial model in the banking network with a digital technology approach by Afshin Nobakht, majid nasiri, parviz Saeedi

“…A questionnaire was used to collect data. AMOS software and Interpretive Structural Modeling (ISM) were used for data analysis. …”
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Inflammatory Indices and MAFLD Prevalence in Hypertensive Patients: A Large-Scale Cross-Sectional Analysis from China by Shen D, Cai X, Hu J, Song S, Zhu Q, Ma H, Zhang Y, Ma R, Zhou P, Yang W, Hong J, Zhang D, Li N

“…Di Shen,1,&ast; Xintian Cai,2,&ast; Junli Hu,2 Shuaiwei Song,1 Qing Zhu,2 Huimin Ma,2 Yingying Zhang,2 Rui Ma,2 Pan Zhou,2 Wenbo Yang,2 Jing Hong,2 Delian Zhang,2 Nanfang Li2 1Graduate School, Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 2Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute, NHC Key Laboratory of Hypertension Clinical Research, Key Laboratory of Xinjiang Uygur Autonomous Region, Hypertension Research Laboratory, Xinjiang Clinical Medical Research Center for Hypertension (Cardio-Cerebrovascular) Diseases, Urumqi, Xinjiang, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Nanfang Li, Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute, NHC Key Laboratory of Hypertension Clinical Research, Key Laboratory of Xinjiang Uygur Autonomous Region “Hypertension Research Laboratory”, Xinjiang Clinical Medical Research Center for Hypertension (Cardio-Cerebrovascular) Diseases, No. 91 Tianchi Road, Urumuqi, Xinjiang, 830001, People’s Republic of China, Tel +86 8564818, Email lnanfang2016@sina.comObjective: Hypertension development and progression are largely influenced by inflammation, which plays a critical role by activating the immune system and causing damage to the vascular endothelium. Metabolic dysfunction-associated fatty liver disease (MAFLD) is also associated with chronic low-grade inflammation, which drives disease progression via metabolic imbalances and adipose tissue dysfunction. …”
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Risk Factors and Outcome of Sepsis in Traumatic Patients and Pathogen Detection Using Metagenomic Next-Generation Sequencing by Yiqing Tong, Jianming Zhang, Yimu Fu, Xingxing He, Qiming Feng

“…Patients’ demographic and clinical data were recorded. The outcome measures included mortality during the emergency intensive care unit (EICU), EICU length of stay (LOS), all-cause 28-day mortality, and total ventilator days in 28 days after admission. …”
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Establishing an Electrophysiological Recording Platform for Epidural Spinal Cord Stimulation in Neuropathic Pain Rats by Yang CT, Shyu BC, Lin WT, Lu KH, Lin CR, Wen YR, Chen CC

“…All device implantations or pUHF-SCS per se did not cause evident spinal cord damage. This safe and stable platform provides an in vivo rat model for SCS investigation of mechanisms of action and device innovation.Keywords: spinal cord stimulation, pulsed-ultrahigh-frequency, evoked local field potential, primary somatosensory cortex, anterior cingulate cortex…”
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Network Design and Route Analysis Using Outside Plant by Isaac Adjaye Aboagye, Nii Longdon Sowah, Wiafe Owusu-Banahene, Aryee Shaelijah, Margaret Ansah Richardson, Emmanuel Baah-Boadi

“…The design will help to reduce the cost of repairing damaged cables drastically. Also, the design methodology helped us to develop a backbone network to get closer to the various homes and premises. …”
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