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12641
Effect of Melatonin as an Antioxidant Drug to Reverse Hepatic Steatosis: Experimental Model
Published 2020-01-01“…We analyze the parameters of oxidative stress: malondialdehyde (MDA), 4-hydroxyalkenals (4-HDA), and carbonyls, degree of fat infiltration (analyzed by direct vision by a pathologist and by means of a computer program of image treatment), and serological parameters of lipid metabolism and hepatic damage. These parameters were analyzed in animals to which hepatic steatosis was induced by means of dietary modifications. …”
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12642
Update on Pulmonary Toxicity Induced by New Breast Cancer Treatments
Published 2025-01-01“…Overall, the risk of pulmonary toxicity is quite low but in some cases lung damage can be fatal. We conducted an update including the available published data regarding the incidence, mechanisms of pathogenesis, clinical presentations, and treatment of lung toxicity induced by new anticancer drugs. …”
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12643
Epitranscriptome profiles reveal participation of the RNA methyltransferase gene OsMTA1 in rice seed germination and salt stress response
Published 2025-01-01“…Results The knockout of OsMTA1 resulted in a decreased level of m6A methylation and delayed seed germination, together with increased oxidative damage in the osmta1-1 mutant, especially under salt stress, indicating that OsMTA1 performs a crucial function in rice seed germination and salt stress response. …”
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12644
İlgi Sıralamalarının Artırımlı Olarak Geliştirilmesi: Pennant Erişimle Desteklenen Yeni Bir Yöntem Önerisi
Published 2022-06-01“…Bulgular: Bulgular konu modelleme algoritması ile elde edilen ilgi sıralamalarında makalelerin başlıklarında ve özetlerinde geçen bazı terimlerin bazen göz ardı edilebildiğini göstermektedir. Ama bu sıralamalar atıf verilerine dayanan pennant erişimle desteklendiğinde, kullanılan terimlerin bağlamları hakkında ek bilgiler elde edilmekte ve sonuçta ilgi düzeyleri daha yüksek ve çeşitli (interdisipliner) makaleler içeren daha zenginleştirilmiş ilgi sıralamaları oluşturulmaktadır. …”
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12645
Exploring the potential benefits of areca nut extract in animal production: a review
Published 2025-02-01“…Its remarkable anti-inflammatory and antioxidant potential, along with its outstanding performance in antibacterial, antifungal, and antiviral activities, plays a crucial role in inhibiting various pathogens and protecting cells from oxidative damage. This review aims to comprehensively explore the biological activities of areca nut extract and delve into its practical application potential in enhancing animal production efficiency and promoting sustainable livestock development.The pervasive presence of antibiotic residues—including tetracyclines, sulfonamides, and quinolones—in agricultural products such as meat, milk, and eggs has raised significant concerns due to their extensive use in animal husbandry. …”
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12646
Saussurea gossypiphora extracts reduce inflammation by reversing inflammatory cytokine levels in in-vitro and in-vivo
Published 2025-02-01“…Wistar rats upon carrageenan induced paw edema showed significant reduction in paw edema and volume upon oral administration of MESGD within 3 h, indicating its significant anti-inflammatory activity. …”
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12647
Assessment of the optimal frequency of insecticide sprays required to manage fall armyworm (Spodoptera frugiperda J.E Smith) in maize (Zea mays L.) in northern Ghana
Published 2022-01-01“…Infestations were higher in the untreated control (no spray) but decreased with increases in number of spray applications in insecticide treated plots. Again, crop damage was low in Emastar 112 EC treated maize. This variable also decreased with an increase in the number of spray applications. …”
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12648
Socially inclusive valorization of gold mill tailings from the small-scale gold mining sector
Published 2024-10-01“…Adequate maintenance of tailings storage facilities, community awareness of waste-related risks and hazards, legal frameworks and financial backing to encourage waste utilization, local community empowerment, and adherence to occupational health and safety guidelines in waste management are essential strategies to bridge existing disparities and foster a socially inclusive approach to mine waste valorization.CONCLUSION: The gold mill tailings contain hazardous substances and fine dust, potentially damaging the nearby ecosystem and community. It is essential to prioritize the maintenance of a well-managed tailings storage facility in order to avoid contamination. …”
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12649
Study of the Shock Absorption Effectiveness of Air Cushions
Published 2024-12-01“…During these experiments, various jump cushions from different manufacturers with air-filled frames fed via air tanks were used. The data gathered together with video recordings of those tests were then thoroughly analysed. …”
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12650
An Experimental Study on Mechanical Properties and Fracture Characteristics of Saturated Concrete under Coupling Effect of Low Temperature and Dynamic Load
Published 2022-01-01“…The water-saturated low-temperature state of the concrete void is filled with ice crystal particles; for low-temperature water-saturated concrete in the impact of the dynamic load, the microstructure is affected by the ice crystal structure which is not easy to change; the specimen along the axial force direction microdefect development produces a crack, the crack along the parallel to the pressure direction of cracking, through the two ends of the specimen, and finally produces axial splitting tensile damage. The research results have important theoretical significance for the safety design of low temperature saturated concrete structures.…”
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12651
Heavy metals contamination in geothermal medicinal plant extract; Chromolaena odorata Linn
Published 2023-10-01“…The presence of cadmium in the extract at a high concentration could cause its translocation to the human body, eventually leading to multiple organ damage. Therefore, the extract of Chromolaena odorata leaves collected from a geothermal area should be consumed with caution for possible cadmium intoxication.…”
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12652
Limited Diagnostic Value of miRNAs in Early Trauma-Induced Liver Injury: Only miRNA-122 Emerges as a Late-Phase Marker
Published 2025-01-01“…This study investigates whether specific liver-related microRNAs (miRNAs) are released into the circulation in trauma patients with liver injury and whether they can indicate liver damage in the early phase after major trauma. <b>Methods</b>: A retrospective analysis of prospectively collected data and blood samples from 26 trauma patients was conducted. …”
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12653
Disproportionate, differential and targeted treatment: people who use drugs’ experiences of policing during the COVID-19 pandemic
Published 2025-01-01“…Qualitative data were analysed thematically and integrated with quantitative results. …”
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12654
Urine proteomics defines an immune checkpoint-associated nephritis signature
Published 2025-01-01“…Delayed or incorrect diagnosis of ICI-AIN is particularly detrimental, as over 50% of patients are at risk of permanent renal damage. Thus, there is an urgent need for non-invasive biomarkers that can rapidly and accurately distinguish ICI-AIN from other causes of AKI.The urine and plasma proteome contain actively secreted proteins that provide real-time insights into dynamic physiological processes. …”
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12655
MT2A promotes angiogenesis in chronically ischemic brains through a copper–mitochondria regulatory mechanism
Published 2025-02-01“…HUVEC activity and mitochondrial structure and function were detected to explore the ability of MT2A to alleviate CPO-induced damage. Finally, a rat model of 2-vessel occlusion plus encephalo-myo-synangiosis (2VO + EMS) with CPO was established to test the proangiogenic effect of MT2A through the copper–mitochondria regulatory mechanism in chronically ischemic brains. …”
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12656
The use of Geographic Information Systems as innovative tools for sustainable development strategies and enhancing the efficiency of forest sector entities
Published 2024-10-01“…The economic efficiency of GIS for forestry entities is manifested through the positive effects of integrating spatial data into automated processes for data collection, accounting, economic analysis of forest resources, forecasting changes, and management support. …”
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12657
Trichinella spiralis excretory/secretory proteins mediated larval invasion via inducing gut epithelial apoptosis and barrier disruption.
Published 2025-01-01“…<h4>Conclusions</h4>T. spiralis IIL ESP induced gut epithelial apoptosis, reduced the TJs expression, damaged gut epithelial integrity and barrier function, and promoted larval invasion. …”
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12658
Human Umbilical Cord Mesenchymal Stem Cells Attenuate Ocular Hypertension-Induced Retinal Neuroinflammation via Toll-Like Receptor 4 Pathway
Published 2019-01-01“…Glaucoma is characterized by progressive, irreversible damage to the retinal ganglion cells (RGCs) and their axons. …”
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12659
Optimizing selenium-enriched yeast supplementation in laying hens: Enhancing egg quality, selenium concentration in eggs, antioxidant defense, and liver health
Published 2025-01-01“…However, higher supplementation levels (6.0 mg/kg) resulted in liver damage, underscoring the importance of careful dosage consideration.…”
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12660
Mitochondrial Gene Expression of Three Different Dragonflies Under the Stress of Chlorpyrifos
Published 2025-01-01“…CPF exhibits its toxicity primarily through the inhibition of the acetylcholinesterase (AChE) enzyme, while mitochondrial damage and dysfunction have also been observed. The present study quantified the transcript levels of mitochondria protein-coding genes (mtPCGs) using quantitative real-time polymerase chain reaction (<i>RT-qPCR</i>) in samples of larvae of three dragonfly species (<i>A. parthenope</i>, <i>E. elegans</i>, and <i>G. confluens</i>) under different levels of CPF stress. …”
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