Meta-analysis of the association between overexpression of RAD51 family genes and prognosis and clinical features in breast cancer by Yong-Cheng Liu, Jun Shen

“…Abstract The RAD51 family of genes play a crucial role in the repair of DNA damage, and increasing evidence suggests a close link between the aberrant expression of RAD51 family genes and the development of breast cancer. …”
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Plant growth promoting rhizobacteria in promoting sustainable agriculture by V. Dhayalan, K. Sudalaimuthu

“…Thus, excessive chemical fertilizer has been used to quickly turn out more outstanding food production, leading to more significant damages to soil ecosystem and human health. Henceforth, bio-fertilizers find the best alternatives to chemical fertilizers. …”
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Shengxue Busui Decoction activates the PI3K/Akt and VEGF pathways, enhancing vascular function and inhibiting osteocyte apoptosis to combat steroid-induced femoral head necrosis by Manting Liu, Jiexiang Ye, Runtian Wu, Dongqiang Luo, Tao Huang, Dandan Dai, Kexin Wang, Yanping Du, Junwen Ou

“…In vivo, SBD intervention significantly reduced bone structural damage and apoptosis, decreasing the rate of empty bone lacunae. …”
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Prediction of Heavy Metals Values for South-East of Baghdad Study Area by Eman Abdul Rahman, Muthaina Abdullah Mustafa

“…This study aims to estimate the damage and seriousness of heavy metals pollution in the soil surrounding these factories. …”
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GENOME POLITICS: STRATEGY AND TACTICS by Jonas Rubikas

“…Evidence of that is the damage to mental functions in various disorders of genome. …”
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hUC-MSC preserves erectile function by restoring mitochondrial mass of penile smooth muscle cells in a rat model of cavernous nerve injury via SIRT1/PGC-1a/TFAM signaling by Mengbo Yang, Xinda Chen, Ming Zhang, Xiaolin Zhang, Dongdong Xiao, Huiming Xu, Mujun Lu

“…It remains unclear whether hUC-MSC can ameliorate mitochondrial damage in CCSMCs. In this study, we aimed to investigate the impacts of hUC-MSC on the mitochondrial mass and function of CCSMCs, as well as elucidate its underlying molecular mechanism. …”
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The management and clinical outcome of paracetamol poisoning in South African adults: A single-centre retrospective review by C Kotze, J Swanepoel, E C Kruger, E Decloedt

“…Demographics, clinical and laboratory data were obtained. Management practices and clinical outcomes were assessed. …”
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Cerpen Hamasa An-Nujum Karya Najib Mahfudz: Kajian Sosiologi Sastra by Khoiru Syafa'atin Noviana

“…This research uses qualitative descriptive analysis with data analysis techniques used in the form of (1) data reduction, (2) data presentation, and (3) data verification. …”
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Suberosin attenuates rheumatoid arthritis by repolarizing macrophages and inhibiting synovitis via the JAK/STAT signaling pathway by Huan Liu, Qianwei Li, Yuehong Chen, Min Dong, Hongjiang Liu, Jiaqian Zhang, Leiyi Yang, Geng Yin, Qibing Xie

“…Conclusion SBR significantly reduced clinical symptoms, joint pathological damage, and expression inflammatory cytokine expression in CIA mice. …”
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Real-World Health Care Outcomes and Costs Among Patients With Juvenile Idiopathic Arthritis in Spain by Jordi Antón, Estefania Moreno Ruzafa, Mireia Lopez Corbeto, Rosa Bou, Judith Sánchez Manubens, Sonia Carriquí Arenas, Joan Calzada Hernández, Violetta Bittermann, Carolina Estepa Guillén, Juan Mosquera Angarita, Lucía Rodríguez Díez, Estíbaliz Iglesias, Miguel Marti Masanet, Berta Lopez Montesinos, Maria I. González Fernández, Alfonso de Lossada, Carmen Peral, Mónica Valderrama, Noelia Llevat, María Montoro Álvarez, Immaculada Calvo Penadés

“…If inflammation is not adequately treated, joint damage, long-term disability, and active disease during adulthood can occur. …”
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Progressive subchondral bone cyst formation following autologous chondrocyte implantation with all-suture anchors: a Case Report with histological evaluation by Takuma Kaibara, Eiji Kondo, Masatake Matsuoka, Koji Iwasaki, Tomohiro Onodera, Daisuke Momma, Zen-Ichi Tanei, Shinya Tanaka, Norimasa Iwasaki

“…These observations may inform future strategies for the early detection of SBC formation and its progression, as well as timely intervention to prevent further joint damage in similar cases, though further research is needed to establish broader clinical implications.…”
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Current status and factors influencing kinesiophobia in patients with meniscus injury: a cross-sectional study by Faqiang Tang, Pan Xu, Cai Jiang, Xiaohua Ke, Dunbing Huang, Yaling Dai, Zhonghua Lin, Shizhong Wang

“…The knee range of motion test was used to determine limitations in knee joint mobility, whereas magnetic resonance imaging (MRI) was used to assess the severity of meniscus damage. Several validated scales were administered: the Tampa Scale of Kinesiophobia (TSK-17) to measure kinesiophobia, the visual analog scale (VAS) to assess pain intensity, the general self-efficacy scale (GSES) to evaluate self-efficacy, and the Lysholm knee score (LKS) to assess knee functional status. …”
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Pirfenidone regulates seizures through the HMGB1/TLR4 axis to improve cognitive functions and modulate oxidative stress and neurotransmitters in PTZ-induced kindling in mice by Mansi Dahalia, Sparsh Gupta, Haya Majid, Divya Vohora, Nidhi

“…Histopathological analysis revealed that pirfenidone ameliorated cellular disintegration and neuronal damage in the hippocampus and cortex.ConclusionPirfenidone shows potential as an anticonvulsant, anti-inflammatory, hepatoprotective, and neuroprotective agent, with additional benefits in improving cognition and oxidative stress profiles in epilepsy treatment. …”
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Quantifying the spatial patterns of retinal ganglion cell loss and progression in optic neuropathy by applying a deep learning variational autoencoder approach to optical coherence... by Jui-Kai Wang, Jui-Kai Wang, Brett A. Johnson, Zhi Chen, Zhi Chen, Honghai Zhang, Honghai Zhang, David Szanto, Brian Woods, Brian Woods, Michael Wall, Young H. Kwon, Young H. Kwon, Edward F. Linton, Edward F. Linton, Andrew Pouw, Mark J. Kupersmith, Mark J. Kupersmith, Mark J. Kupersmith, Mona K. Garvin, Mona K. Garvin, Mona K. Garvin, Mona K. Garvin, Randy H. Kardon, Randy H. Kardon

“…IntroductionGlaucoma, optic neuritis (ON), and non-arteritic anterior ischemic optic neuropathy (NAION) produce distinct patterns of retinal ganglion cell (RGC) damage. We propose a booster Variational Autoencoder (bVAE) to capture spatial variations in RGC loss and generate latent space (LS) montage maps that visualize different degrees and spatial patterns of optic nerve bundle injury. …”
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Probing the Relationships Between Mandaeans (the Followers of John the Baptist), Early Christians, and Manichaeans by Brikha H. S. Nasoraia

“…Mandaean culture and the Mandaic Aramaic language was of high report in the so-called Patristic period covered by this Special Issue, even in the Arabian Peninsula up until the rise of Islam (634 CE onward), and Mandaeans were honored as a third “People of the Book”—the Sabians (<i>Ṣābeʾun; or ṣobba</i> in modern Iraqi Arabic)—in the Qur’an (2:62; 5:69; 22:17); in the Muslim world, many Mandaic speakers switched language to colloquial Iraqi Arabic and (Arabicized) Persian. …”
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The injury effect of osteopontin in sepsis-associated lung injury by Qian Wang, Zhicai Yu, Zhixin Song, Xue Lu, Zhu Li, Dandan Pi, Jing Li, Feng Xu

“…Intravenous administration of OPN inhibitor into the tail vein decreased the mortality rate (HR = 0.2695, p = 0.0015), suppressed systemic inflammatory responses and mitigated lung tissue damage. The concentration of tumour necrosis factor (TNF)-α, IL-6 and IL-1β in serum of CLP mice treated with OPN inhibitor decreased compared with CLP mice. …”
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Study on the Effect of Isotropic Initial Stress on the Anchoring Performance of Self-Expanding Bolts by Jie Liu, Hongya Li, Yunzhou Li, Yunan Yang, Tao Sun, Rui Song, Rongqi Sun

“…It is pointed out that this effect can greatly improve the ductility of the anchoring system and the ultimate energy consumption value of damage. A prediction model for the ultimate pull-out force of self-expanding bolts is established. …”
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Exosomes secreted by ATF3/Nrf2-mediated ferroptotic renal tubular epithelial cells promote M1/M2 ratio imbalance inducing renal interstitial fibrosis following ischemia and reperfu... by Qiao Tang, Jiatao Xie, Yifei Wang, Chong Dong, Chong Dong, Qian Sun

“…The IR group had more significant mitochondrial damage and higher PTGS2 and TFRC mRNA levels than those in the sham group. …”
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Eficacia de inhibidores de nitrito de calcio (CNI) en concreto agrietado by Pedro Montes-Garcia, H. Z. López-Calv, T. W Bremner

“…The specimens were also visually inspected on regular basis and the surface damage was recorded. It was found that for most of the cases the use of CNI inhibitor was beneficial in both uncracked and cracked concrete.…”
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Altered expression profile of plasma exosomal microRNAs in exclusive electronic cigarette adult users by Dongmei Li, Zidian Xie, Sadiya Bi Shaikh, Irfan Rahman

“…Overexpression of hsa-miR-125b-5p promoted DNA damage in bronchial epithelial cells. These findings suggest an elevation of carcinogenic cellular signaling pathways in exclusive e-cigarette users.…”
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