Effect of Electroacupuncture Prestimulation with Mental Tri-Needles on the Inflammatory Response of Hippocampus in Aged Rats with Perioperative Neurocognitive Disorders by WANG Xiangfeng, HUANG Jinyan, LIU Wei, LUO Huiqin, WANG Guanhui, LIN Qin, CHEN Bin

“…Open field experiment and water maze test were used to evaluate the cognitive function; ELISA method was used to detect interleukin (IL)-1β, IL-6 and tumor necrosis factor (TNF)-α in the plasma; HE staining was used to observe the cell morphology of hippocampal tissue; TUNEL staining was used to observe the apoptosis of hippocampal tissue; Western blot and real-time fluorescence quantitative PCR were used to detect the protein content and mRNA expression of IL-1β, IL-6 and TNF-α in hippocampal tissue.Results(1) Cognitive function: compared with the control group and the anesthesia group, the time of staying in the central quadrant, the number of crossings of the quadrant, the number of standing ups, the total distance of swimming, the swimming speed and the number of platform crossings in the operation group significantly decreased, and the latency and the time of staying in the target quadrant were significantly prolonged (<italic>P</italic>&lt;0.05); compared with the operation group, the time of staying in the central square, the number of crossings of the quadrant, the number of standing ups, the total distance of swimming, the swimming speed and the number of platform crossings in the acupuncture group significantly increased, and the latency and the time of staying in the target quadrant were significantly shortened (<italic>P</italic>&lt;0.05). (2) Levels of IL-1β, IL-6 and TNF-α in plasma: compared with the control group, the levels of IL-1β, IL-6 and TNF-α significantly increased in the anesthesia group, operation group and acupuncture group (<italic>P</italic>&lt;0.05); compared with the anesthesia group, the levels of IL-1β, IL-6 and TNF-α in the operation group significantly increased (<italic>P</italic>&lt;0.05); compared with the operation group, the levels of IL-1β, IL-6 and TNF-α in the acupuncture group significantly decreased (<italic>P</italic>&lt;0.05). (3) Morphology and apoptosis of hippocampal neurons: the most sever injury of hippocampal neurons occured in the operation group, showing as interstitial edema and a small amount of glial cell proliferation, while the injury of hippocampal neurons was slight and the morphology was relatively normal in the acupuncture group. Compared with the control group and the anesthesia group, the percentages of apoptotic cells in the hippocampus of the operation group and the acupuncture group significantly increased (<italic>P</italic>&lt;0.05); and compared with the operation group, the percentage of apoptotic cells in the hippocampus of the acupuncture group significantly decreased (<italic>P</italic>&lt;0.05). (4) Protein contents and mRNA levels of IL-1β, IL-6 and TNF-α in hippocampus: compared with the control group and the anesthesia group, the protein contents and mRNA levels of IL-1β, IL-6 and TNF-α in the operation group significantly increased (<italic>P</italic>&lt;0.05); compared with the operation group, the protein expression of IL-1β, IL-6 and TNF-α and their mRNA levels in the acupuncture group significantly decreased (<italic>P</italic>&lt;0.05).ConclusionEA prestimulation with mental trineedles can reduce the injury and apoptosis of hippocampal cells in aged rats with PND, and improve cognitive function, which may be related to the inhibition of the overexpression of IL-1β, IL-6 and TNF-α in the hippocampus of aged rats and reducing the inflammatory reaction in brain tissue.…”
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Uncovering the Mechanisms of BaBaoWuDanYaoMo Against Influenza A Virus and Virus-Induced Inflammation Based on Network Pharmacology and Pharmacological Evaluation by Lei B, Su Y, Chen R, Chen Z, Liu B, Chen Y, Zhou M, Wang X, Ma Q

“…BALB/c mice were intranasally infected with A/PR/8/34 (H1N1) (PR8) and orally administrated BB (500 mg/kg, 250 mg/kg and 125 mg/kg) or oseltamivir daily. The normal group was orally administrated PBS for 5 days. …”
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Effect of Sunflower (Helianthus annus L.) Hulls with Different Particle Sizes on Growth Performance and Physiological Responses of Broiler Chickens Fed Different Levels of Protein by Najibeh Beigzadeh, Smayyeh Salari, Faegheh Zaefarian, Shima Hosseinifar

“…The treatments included 3 types of dietary sunflower hull types (without hulls, 4% with 1 mm particle size, and 4% with 5 mm particle size) and 2 crude protein (CP) levels (normal and a 10% reduction). Feed intake (FI) and body weight gain (BWG) were recorded, and the feed conversion ratio (FCR) was calculated. …”
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Kuiyangling Enema Alleviates Ulcerative Colitis Mice by Reducing Levels of Intestinal NETs and Promoting HuR/VDR Signaling by Zhang D, Zhu Z, He Z, Duan S, Yi Q, Qiu M, Dai X, Su G, Li K, Xu L, Liu D, Wu Y, Gao Y, Li R, Guo S

“…The aim of this study is to explore the mechanism of Kuiyangling in the treatment of ulcerative colitis.Methods: A mouse model of ulcerative colitis using 3% DSS water was considered, and model, normal, Kuiyangling medium- (5 g·kg− 1) and high-dose (10 g·kg− 1), and mesalazine (50 mg·kg− 1) groups were created. …”
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Early prediction of long COVID-19 syndrome persistence at 12 months after hospitalisation: a prospective observational study from Ukraine by Dmytro Chumachenko, Tetyana Chumachenko, Oleksii Honchar, Tetiana Ashcheulova

“…Logistic regression and machine learning-based binary classification models have been developed to predict the persistence of LCS symptoms at 12 months after discharge.Conclusions Compared with post-COVID-19 patients who have completely recovered by 12 months after hospital discharge, those who have subsequently developed ‘very long’ COVID were characterised by a variety of more pronounced residual predischarge abnormalities that had mostly subsided by 1 month, except for steady differences in the physical symptoms levels. A simple artificial neural networks-based binary classification model using peak ESR, creatinine, ALT and weight loss during the acute phase, predischarge 6-minute walk distance and complex survey-based symptoms assessment as inputs has shown a 92% accuracy with an area under receiver-operator characteristic curve 0.931 in prediction of LCS symptoms persistence at 12 months.…”
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Plateau hypoxia improves tumor immune microenvironment and inhibits subcutaneous tumor growth of colorectal cancer by ZHAO Sijie, WANG Meng, GAO Yuan

“…The mice in the plateau hypoxic group were housed in a low-pressure oxygen （10%） chamber to simulate an altitude of approximately 5 600 m， while the mice of the other group was maintained in SPF-grade normal atmospheric conditions （21% oxygen， at an altitude of about 300 m）. …”
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Behaviour of a speargun with a novel muzzle by V. Nigrelli, M. Mucera, T. Ingrassia

“…For this reason, during the results analysis phase, the strain values measured on the roller speargun have been ‘normalized’ by increasing them of a value equal to the ratio of the maximum forces due to the rubber bands. …”
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Measurement and Evaluation of Social Resilience Indicators in the Historical Neighborhoods of Tabriz City (Case Study: Sorkhab Neighborhood of Tabriz) by Leila Rahimi, Mahta Choobineh

“…This study focused on evaluating the indicators of social resilience in the historical neighborhood of Sorkhab in Tabriz as these historical areas were among the most vulnerable parts of the city and played a crucial role in restoring normal social conditions. The research adopted a descriptive-analytical approach in terms of its nature and methodology. …”
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Developing and presenting a mathematical model for the purpose of organizational culture architecture based on creating alignment between the strategic reference points of organiza... by Elyas hasanzadeh Shweili, Mir Mehrdad peidaie, Ali reza Rezghi Rostami

“…Semi-structured interview was used in this research. Delphi and fuzzy neural system were used to collect and analyze data. …”
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Hemşirelik Öğrencilerinin Ahlaki Kimlik ve Empati Düzeyleri Arasındaki İlişki by Hilal Seki Öz, Özkan Sarıkaya, Didem Ayhan

“…Verilerin normallik analizi için Kolmogorov-Smirnov Testi yapılmış olup, veriler normal dağılma uymadığından parametrik olmayan testler kullanılmıştır. …”
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The Effect of Postoperative Tranexamic Acid and Dexamethasone on Quality of Recovery After Arthroscopic Rotator Cuff Repair: a Double-Blinded, Randomized Controlled Trial by Jiang X, Xu C, Yuan C, Gao W, Liu W, Wang Y, Wang H, Yu W, He Y

“…Patients were randomized to intravenously receive 200mL of normal saline (control group), 200mL of 1g TXA in saline (TXA group), or 200 mL of 1g TXA and 5mg DEX in saline (TXA+DEX group) within 2 hours postoperatively. …”
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Physical and Mechanical Properties of Green Cementless Mortar Incorporating Waste Paper Sludge Ash by Aida Nabila Jamaluddin, Siti Asmahani Saad, Siti Aliyyah Masjuki, Wan Nur Firdaus Wan Hassan, Siti Noratikah Che Deraman, Nadiah Md Husain

“… As an alternative to conventional construction material such as normal concrete, waste paper sludge ash (WPSA) based geopolymer is seen as a promising and viable option in construction material selection due to its high amount of aluminum (Al) and silicon (Si) content. …”
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γ-亚麻酸对α-亚麻酸转化为DHA的影响 Effect of γ-linolenic acid on the conversion of α-linolenic acid to DHA by 谢婉菲1，姜珊1，王成成1，王玉明1,2，薛长湖1,2，张恬恬1 " XIE Wanfei1, JIANG Shan1, WANG Chengcheng1, WANG Yuming1,2, XUE Changhu1,2, ZHANG Tiantian1"

“…The mice in the three groups were given a single gavage of normal saline, 300 mg/kg ALA, 300 mg/kg ALA+30 mg/kg GLA, respectively. …”
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Evaluation of Ecological Resilience of Agricultural Ecosystems in Razavi Khorasan Province: Comparison of Integrated and Non-Integrated Ecosystems by Pegah Naghipour, Alireza Koocheki, Mahdi Nasiri mahalati, Soroor Khorramdel

“…The scores of 5 components were aggregated after weighting, by using factor analysis, and normalization to develop a composite resilience index in 1-5 scale.Results and DiscussionThe results showed a significant relationship between the resilience of rural households and the 5 mentioned components where intensification had negative correlation with resilience while the impact of assets, adaptation capacity, biodiversity and use of ecosystem services on household resilience was positive with the highest correlation for biodiversity. …”
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Anti-Inflammatory Effects of Cerium Dioxide Nanoparticles on Peritonitis in Rats Induced by Staphylococcus epidermidis Infection by Yan Li, Hongmei Sun, Zhiqi Yin, Xuexi Guo, Jun Yan

“…Staphylococcus epidermidis solution was injected intraperitoneally with 107 CFU/ml of bacterial solution in the model group, while the control group was injected intraperitoneally with the same amount of normal saline, and the CeO2 and CeO2 + model groups were injected with 0.5 mg/kg CeO2 nanoparticles through the tail vein for 2 h and then injected with saline or bacterial solution for 2 h, respectively. …”
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„O pecunia totius mali regina, fraudis et doli amica...“ Peníze v kultuře středověku by Tomáš Krejčík

“…Christianity had a positive relationship towards money, and the first Christians accepted it as a normal part of life. Money at that time served as a kind of medium, the images on which disseminated a substantial ideology in society, which succumbed to the power of these images. …”
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Mechanism of Inflammation Regulation of α7nAChR in Spleen and Spinal Dorsal Horn of Mice with Paclitaxel-induced Neuropathic Pain by Electroacupuncture on Zusanli Acupoint by PANG Lina, LAN Yanyan, WANG Zhifu, CHEN Xiaomei, YU Xiangmei

“…The model group, electroacupuncture group, intraperitoneal antagonist group and intrathecal antagonist group were injected with paclitaxel (2 mg/kg) every other day for a total of 4 times to establish the PINP model, while the control group was given the same amount of normal saline. After the model was established, the electroacupuncture group, intraperitoneal antagonist group and intrathecal antagonist group received electroacupuncture intervention once every other day from the first day, for 7 times in total. …”
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Diagnosis, treatment, surgical practices and review of the literature in rare coagulation factor deficiencies by Hüseyin Avni Solgun

“…Results The average age of total 19 patients was 11.2 years (range 2,5–17 years). 14 patients were boys (74%) and 5 patients were girls (26%). 10 of the patients (52%) had FVII deficiency (mean FVII: 8,3%, range 2,5–17%), 4 of patients (21%) had FX deficiency (mean FX:16,2%, range 15–17%) and 4 of patients (21%) had FV deficiency (mean FV:14%, range 10–17%) and 1 had FXIII deficiency (1%) respectively. The normal range laboratory reference values for rare blood factor levels in our institute (factor V, VII and X deficencies) is 70–120%. …”
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Black Boarding Academies as a Prudential Reparation by Roy Brooks

“…Using a modified version of their pedagogy—one self-consciously infused with a racial sensibility—BBAs will be able to extend the pipeline to leadership, normally available to upper-income and even middle-income African American students, to low-income African American students. …”
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Consonant Error Patterns in Children with Functional Dysarthria and Dysarthria with Language Retardation by Zhenping LIN, Zhuoming CHEN, Yuchang LI, Na LI, Zhimei LIU, Xian XIE, Dan LI

“…No matter functional dysarthria children or dysarthria with language retardation children were similar to the normal children in the acquisition of pronunciation, the types of errors were related to the pronunciation location and the pronunciation method. …”
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