Novel predictive biomarkers for atonic postpartum hemorrhage as explored by proteomics and metabolomics by Jiangxue Qu, Hai Jiang, Huifeng Shi, Nana Huang, Jiawen Su, Yan Zhang, Lian Chen, Yangyu Zhao

“…Methods Collection of cervicovaginal fluid (CVF) samples from 27 women with atonic PPH and 32 women with normal delivery was performed for metabolomic (LC-MS/MS) and proteomic (LC-MS/MS) detection and subsequent confirmation experiments in this nested case-control study. …”
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Analisis Impedansi Bioelektrik (BIA) pada Atlet Para-Panahan Pria dan Wanita: Sebuah Studi Komparatif by Idya Putra Harjianto, Nur Subekti, Pungki Indarto

“…Atlet laki-laki memiliki berat badan yang lebih berat dengan komposisi massa otot rangka yang lebih besar, sedangkan perempuan lebih gemuk dengan BMI dan Persen lemak tubuh di atas normal. Setiap hari untuk menghilangkan lemak atau menambah massa otot, atlet laki-laki membutuhkan lebih banyak kalori daripada perempuan.…”
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Effect of Kinesiophobia Mediated Disease Perception on Rehabilitation Exercise Adherence in Patients Undergoing Percutaneous Coronary Intervention by LI Juanli, CHEN Fangyuan, ZHENG Xiaopu, CHEN Chen, LI Rui

“…The mediation analysis for categorical dependent variable showed that disease perception could predict the kinesiophobia of the patients (<italic>t</italic>=5.336, <italic>P</italic>&lt;0.01), both kinesiophobia and disease perception could negatively predict the rehabilitation exercise adherence of the patients (<italic>OR</italic>=0.347, <italic>P</italic>&lt;0.01; <italic>OR</italic>=0.456, <italic>P</italic>&lt;0.05), and disease perception could negatively predict the rehabilitation exercise adherence of the patients (<italic>OR</italic>=0.431, <italic>P</italic>&lt;0.05). After normalization of the regression coefficient it showed that kinesiophobia played a partial mediating role between the disease perception and rehabilitation exercise adherence and the intermediary effect accounted for 41.00% of the total effect.ConclusionThe disease perception of patients after PCI can directly predict their rehabilitation exercise adherence, and it can also affect their adherence through the mediating effect of kinesiophobia. …”
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Iodine activates NLRP3 inflammasomes in PBMCs of patients with autoimmune thyroiditis and regulates Th1 and Th17 cell differentiation by Ying Wu, Qingling Guo, Yongping Liu, Xun Gong, Wei Sun, Yushu Li, Chenling Fan, Weiping Teng, Zhongyan Shan

“…Methods: We collected PBMCs and serum samples from 50 patients with AIT with normal thyroid function and 50 controls matched for age and sex. …”
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EZH2/miR-142-3p/HMGB1 axis mediates chondrocyte pyroptosis by regulating endoplasmic reticulum stress in knee osteoarthritis by Yang Chen, Shanshan Dong, Xin Zeng, Qing Xu, Mingwei Liang, Guangneng Liao, Lan Li, Bin Shen, Yanrong Lu, Haibo Si, Peifang Wei

“…The expression of the histone methyltransferase enhancer of zeste homolog 2 (EZH2), microRNA-142-3p (miR-142-3p), and high mobility group box 1 (HMGB1) and the levels of ER stress, pyroptosis, and metabolic markers in normal and OA chondrocytes were investigated by western blotting, quantitative polymerase chain reaction, immunohistochemistry, fluorescence in situ hybridization, fluorescein amidite-tyrosine-valine-alanine-aspartic acid-fluoromethyl ketone (FAM-YVAD-FMK)/Hoechst 33342/propidium iodide (PI) staining, lactate dehydrogenase (LDH) release assays, and cell viability assessments. …”
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Mechanisms of the Effect of Starvation Duration on the Regulation of Feeding Rhythm and Metabolic Physiology of Cultured Large Yellow Croaker (<i>Larimichthys crocea</i>) by Xiaomeng Wang, Huang Liu, Chenglin Zhang, Chen Zhu, Huiyi Liu

“…Meanwhile, the expression of inflammatory factor genes such as IL-1β, IL-10 and TNF-α in the liver increased with the prolongation of starvation time, in which both S8 and S16 groups in the liver were significantly different from the S0 group, and after resumption of feeding, the IL-1β and TNF-α genes of the S8 and S16 groups were significantly different from those of the normal feeding group (<i>p</i> < 0.05), while there was no differentiation for the IL-10 gene. …”
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Chaihu Shugan San and Zuogui Yin synergistically improve premature ovarian failure in a rat model via the PI3K/Akt/mTOR pathway by Fei Zhang, RuiFang Liu, ZhenLing Xu, WenJie Chen, XiYa Lu, Yang Wang

“…Compared to the model group, Chaihu Shugan San, Zuogui Yin, and their combination increased granulosa cell proliferation (P < 0.01), reduced follicular atresia (P < 0.05), and normalized hormone levels (FSH: reduced by 36.5 %; E2: increased by 42.8 %, P < 0.05). …”
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Impact of Prior Chronic Kidney Disease and Newly Detected eGFR Impairment at Admission on Outcomes and Prognosis of Hospitalized COVID-19 Patients &ndash; A Single-Center Cohort St... by Kania M, Terlecki M, Batko K, Rajzer M, Malecki MT, Krzanowski M

“…Group B had the highest risk (OR 3.003, CI 2.298– 3.926) compared to group A (OR 2.020, CI 1.636– 2.494) and group C (reference).Conclusion: COVID-19 patients with prior CKD and newly detected RI have higher odds of in-hospital death compared to those with normal kidney function. Special attention is needed for newly detected RI cases in COVID-19 patients.Keywords: kidney disease, mortality, risk factors, COVID-19, chronic kidney disease, acute kidney injury, SARS-Cov-2…”
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Walnut oil prevents hyperlipidemia induced by high-fat diet and regulates intestinal flora and liver metabolism by Rui Yang, Dan Chen, Yanling Chen, Yage Ma, Chaoyin Chen, Shenglan Zhao

“…The rats were randomly assigned to one of the five groups: the normal group (ND), the model group (HFD), and three walnut oil intervention groups differing in dosage [low-dose (OL, 2.5 g/kg. …”
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Effects of cardiac contractility modulation on autophagy and apoptosis of cardiac myocytes in rabbits with chronic heart failure. by Qingqing Hao, Shilin Lv, Jing Zhang, Huiliang Liu

“…The expression of Bcl-2, ALDH2 protein and mRNA increased after CCM intervention, and the expression of Bax, Caspase-3 protein and mRNA decreased (P<0.05). 3) The apoptosis situation in the Sham group was similar to that of normal myocardium, compared with the Sham group, the number of apoptotic bodies increased, and the apoptosis percentage of cardiomyocytes increased significantly (P<0.05). …”
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Factors influencing waist circumference among urban bank employees in Northeast Ethiopia: a cross-sectional study by Woynshet Yimer, Lakew Asmare, Fikre Bayu Gebeyehu, Tihtna Alemu, Anisa Mehamed, Fanos Yeshanew Ayele

“…Univariate and multivariate linear regression analyzes were performed to identify factors related to waist circumference. Normality, homoscedasticity, significant outliers, and multicollinearity were assessed, and a p-value of less than 0.05, along with a 95% confidence interval, was considered statistically significant.ResultsA total of 345 participants were included in the final analysis, with a 95% response rate. …”
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Soil moisture partitioning strategies in blowouts in the Hulunbeier grassland and response to rainfall by Zhixin Bao, Limin Yuan, Limin Yuan, Limin Yuan, Zhongju Meng, Ezhen Zhang, Lei Zhu, Jinwang Liu

“…IntroductionSoil moisture and soil water retention capacity are key influencing factors for the normal growth and development of vegetation. Understanding the dynamic change characteristics of soil moisture in blowouts and soil water retention capacity is of great significance for the management of blowouts.MethodsThis study employs drying and in situ monitoring methods to select typical blowouts in different regions (sand pits, fringe zones, sand accumulation zones, and sand-grass transition zones) on the Hulunbuir Grassland. …”
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Medical treatment for dry eye in patients with keratoconus after corneal cross-linking by I.A. Bubnova, G.B. Egorova, V.V. Averich, T.S. Mitichkina

“…Total and basic tear production was below normal ranges in 45% and 50%, respectively. In a week after CXL, complete corneal epithelization without any signs of staining with fluorescein was observed in a total of 16 patients. …”
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PSYCHOSOCIAL ILLNESS IN CHILDREN WITH THALASSEMIA: A CASE-CONTROL STUDY by Erum Afzal, Muhammad Aslam Sheikh, Sajjad Hussain Bhaba, Tanveer Ahmed, Imran Iqbal, Muhammad Khalid Iqbal

“…STUDY DESIGN: Case-control  MATERIAL AND METHOD:   In this study 50 children with Thalassemia and 50 normal children were enrolled as case & control according to inclusion and exclusion criteria. …”
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CD32B1, a versatile non-signaling antibody-binding scaffold for enhanced T cell adhesion to tumor stromal cognate antigens by Sara W. Feigelson, Tali Dadosh, Nehora Levi, Anita Sapoznikov, Hadas Weinstein-Marom, Hadas Weinstein-Marom, Dayana Blokon-Kogan, Dayana Blokon-Kogan, Yahel Avraham, Tamar Unger, Gideon Gross, Gideon Gross, Rony Dahan, Ronen Alon

“…We thus generated a non-signaling CD32B1 mutant lacking the ITIM motif (termed ITIM-less CD32B1, or ILCD32B1) and successfully expressed it in human T cells which normally do not express this FcR. The ILCD32B1 expressing lymphocytes bound multiple IgG1 mAbs whose Fc domain was engineered with a 5-residue substitution to reach a nM range of Fc-FcγCR dissociation constants. …”
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Wealth-based inequality in underweight among Scheduled Tribe women in India: a regional analysis by Anshika Singh, Aditya Singh, Mahashweta Chakrabarty, Shivani Singh, Pooja Tripathi

“…Wealth-based inequality in underweight was assessed using the Erreygers normalized concentration index (ECI), while predicted probabilities of underweight, adjusted for relevant variables, were calculated using binary logistic regression. …”
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Identification of Intracranial Germ Cell Tumors Based on Facial Photos: Exploratory Study on the Use of Deep Learning for Software Development by Yanong Li, Yixuan He, Yawei Liu, Bingchen Wang, Bo Li, Xiaoguang Qiu

“…MethodsA multicenter, phased approach was adopted for the development and validation of a deep learning model, GVisageNet, dedicated to the screening of midline brain tumors from normal controls (NCs) and iGCTs from other midline brain tumors. …”
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Influence of spine biomechanics and sagittal balance on the outcome of lumbar discectomy by José Poblete Carrizo, José Poblete Carrizo, Jesús Martínez, Julio González, Alejandra Mosteiro, Ramon Torné, Ramon Torné, Alberto Di Somma, Alberto Di Somma, José Ríos, Joaquim Enseñat, Joaquim Enseñat, Salvador Fuster, Salvador Fuster

“…Noteworthy, the radicular and lumbar pain and disability outcomes 12 and 24 months after surgery were significantly better in the group with normal sagittal balance (ODI 14.52 vs. 40.06 p &lt; 0.001; radicular VAS 2.74 vs. 5.58 p &lt; 0.001; lumbar VAS 3.61 vs. 4.06 p &lt; 0.001).ConclusionLumbar degenerative disc disease represents a major burden for healthcare systems; thus, its management is determinant. …”
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The value of blood lactate and lactate clearance rate in evaluating the prognosis of athletes with heat illness of varying degrees after high-intensity exercise by Li Yu, Xuehui Dong, Huanhuan Li, Lili Mi

“…Core body temperature normalized in both groups, but the good prognosis group showed a more rapid decline, with temperatures of 37.4 ± 0.6 °C at 2 h and 36.8 ± 0.4 °C at 6 h in the good prognosis group, and 38.8 ± 0.8 °C at 2 h and 38.2 ± 0.9 °C at 6 h in the poor prognosis group. …”
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La supervivencia más allá de cien años y más by Roberto Ham Chande

“…La distribuciónde dx se ajusta a una curva normal en el lado derecho, cuya media se va incrementando en el tiempo mientras la desviación estándar disminuye, lo que corresponde a la forma esperada de acuerdo con experiencias y planteamientos teóricos. …”
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