Triglyceride glucose index–body mass index as a predictor of coronary artery disease severity in patients with H-type hypertension across different glucose metabolic states by Lian Wang, Zijin Li, Rui Qiu, Li Luo, Xisheng Yan

“…Receiver operating characteristic (ROC) curves were used to evaluate the predictive value of TyG-BMI in detecting the severity of CAD in different glucose metabolism states, including normal glucose regulation (NGR), pre-diabetes mellitus (Pre-DM), and diabetes mellitus (DM). …”
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GPR137-RAB8A activation promotes ovarian cancer development via the Hedgehog pathway by Chao Tang, Lin Li, Chongying Zhu, Qiang Xu, Zihao An, Shouying Xu, Chao Lin

“…Results GPR137 expression was significantly higher in collected clinical OC tissues, compared with the adjacent normal tissues. Consistently, suppression of GPR137 inhibited human SK-OV-3 and A2780 OC cell proliferation, migration, invasion, and colony formation, whereas overexpression of GPR137 in human OC HO8910 cell exerted the opposite effects on cell biological behaviors. …”
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Whole transcriptome analysis and construction of gene regulatory networks of granulosa cells from patients with polycystic ovary syndrome (PCOS) by Yuan Yuan, Daiterigele, Qian Zhang, Chen Du

“…Methods Three patients with PCOS (according to the 2003 Rotterdam diagnostic criteria) and three normal controls were selected. We used the standard long protocol to collect granulosa cells from two groups, who underwent assisted reproduction at the Reproductive Medicine Center of the Affiliated Hospital of Inner Mongolia Medical University, China. …”
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Lipid analysis of tear fluid as a diagnostic tool for meibomian gland dysfunction by L.R. Takhauova, A.A. Guseva, A.A. Krylova, O.I. Krivosheina

“…In meibomian gland dysfunction (MGD), the meibum thickens and acquires a higher melting point than normal. This leads to a decrease in the amount of nonpolar and amphiphilic lipids in the meibomian gland secretion and tear film. …”
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The method of targeted delivery of drugs to the posterior segment of the eye by A.E. Egorov, D.V. Katz, Baeva N.G, A.B. Movsisyan

“…<br> <b>Patients and methods:</b> the study included 67 patients (97 eyes) with moderate and advanced stages of open-angle glaucoma and normalized intraocular pressure. The examination for all patients included: anamnesis of disease, life, also a comprehensive ophthalmological examination was carried out, including visual acuity, tonometry, biomicroscopy, automated perimetry using kinetic visual field and central threshold test.…”
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Optimization and characterization studies of poultry waste valorization for peptone production using a newly Egyptian Bacillus subtilis strain by Hajar Saeed, Anthony Ragaey, Ziad Samy, Viola Ashraf, Aly ElMostafa, Norhan Ahmad, Enjy Bebawy, Nour ElHoda M. Sorour, Salwa M. El-Sayed, Ashraf Bakry, Naglaa Ebeed, Hesham Elhariry, Thanaa El-Noby, Samah H. Abu-Hussien

“…The produced peptone exhibited minimal cytotoxicity at lower concentrations (≤ 1 mg/mL), with cell viability exceeding 94% against normal human skin fibroblast (HSF) cells. However, higher concentrations (≥ 3 mg/mL) displayed increased cytotoxic effects. …”
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Analysis of Acoustic Surface Wave Focused Unidirectional Interdigital Transducers Using Coupling-of-Mode Theory by Guopeng Hui, Tinglun Ao, Haotian Liu, Minglei Li, Chen Chen

“…The SAW maximum amplitude of the EWC-FEFUDT (Design 3) is increased by about <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mn>1.5</mn><mo>×</mo><mn>1</mn><msup><mrow><mn>0</mn></mrow><mrow><mo>−</mo><mn>4</mn></mrow></msup><mo> </mo><mi>µ</mi><mi mathvariant="normal">m</mi></mrow></semantics></math></inline-formula> compared to that of the focused interdigital transducers (FIDTs). …”
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Gut-brain axis mediated by intestinal content microbiota was associated with Zhishi Daozhi decoction on constipation by Leyao Fang, Leyao Fang, Leyao Fang, Xin Yi, Xin Yi, Junxi Shen, Junxi Shen, Na Deng, Na Deng, Xinxin Peng, Xinxin Peng

“…The stool of mice in the low-dose ZDD group (CLD), medium-dose ZDD group (CMD), and high-dose ZDD group (CHD) exhibited a smoother texture, closely resembling that of the normal group (CNM). 5-HT levels in the CMM group were significantly lower than in the CNM, CLD, and CHD. …”
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Polymorphic Single‐Nucleotide Variants in miRNA Genes and the Susceptibility to Colorectal Cancer: Combined Evaluation by Pairwise and Network Meta‐Analysis, Thakkinstian's Algorit... by Qing Liu, Ivan Archilla, Sandra Lopez‐Prades, Ferran Torres, Jordi Camps, Miriam Cuatrecasas

“…Results Totally, 39 case–control trials involving 18,028 CRC cases, and 21,816 normal participants were included in the study. Eleven SNPs within nine genes were examined for their predisposition to CRC. miR‐27a (rs895819) was found to significantly increase CRC risk among overall population (OR 1.58, 95% CI: 1.32–1.89) and Asians (OR 1.62, 95% CI: 1.31–2.01), with the recessive models identified as the optimal models. …”
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Age-related differences of subjective visual vertical perception in adults—a functional near-infrared spectroscopy study by Jun Lu, Jun Lu, Xiang Gong, Meng-Huan Wang, Ruo-Xin Zhao, Yu-Chen Wang, Ying-Ying Shen, Rong Cao, Guang-Xu Xu, Guang-Xu Xu

“…BackgroundThe perception of Subjective Visual Vertical (SVV) is crucial for postural orientation and significantly reflects an individual’s postural control ability, relying on vestibular, visual, and somatic sensory inputs to assess the Earth’s gravity line. The neural mechanisms and aging effects on SVV perception, however, remain unclear.ObjectiveThis study seeks to examine aging-related changes in SVV perception and uncover its neurological underpinnings through functional near-infrared spectroscopy (fNIRS).MethodsIn a comparative study of 19 young and 19 older adults, the standardized SVV task executed in Eprime 3.0 software evaluated participants’ SVV orientation and uncertainty. …”
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Comparative Analysis of Tillage Indices and Machine Learning Algorithms for Maize Residue Cover Prediction by Jian Li, Kewen Shao, Jia Du, Kaishan Song, Weilin Yu, Zhengwei Liang, Weijian Zhang, Jie Qin, Kaizeng Zhuo, Cangming Zhang, Yu Han, Yiwei Zhang, Bingrun Sui

“…MRC estimation models were built using six machine learning algorithms, including back propagation neural network (BPNN), random forest (RF), support vector regression (SVR), extreme gradient boosting (XGBoost), Stacking1, and Stacking2. …”
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Co-isolation of human donor eye cells and development of oncogene-mutated melanocytes to study uveal melanoma by Yunxi Chen, Eva Jin, Mohamed Abdouh, Éric Bonneil, Daniel Alexander Jimenez Cruz, Thupten Tsering, Qianqian Zhou, Aurélie Fuentes-Rodriguez, Alexandra Bartolomucci, Alicia Goyeneche, Solange Landreville, Miguel N. Burnier, Julia V. Burnier

“…Abstract Background Uveal melanoma (UM) is the most common intraocular tumor in adults, arises either de novo from normal choroidal melanocytes (NCMs) or from pre-existing nevi that stem from NCMs and are thought to harbor UM-initiating mutations, most commonly in GNAQ or GNA11. …”
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Steatohepatitis-induced vascular niche alterations promote melanoma metastasis by Johannes Hoffmann, Julia Schüler, Bianca Dietsch, Sina Wietje Kürschner-Zacharias, Carsten Sticht, Felix A. Trogisch, Maren Schreitmüller, Tinja Baljkas, Kai Schledzewski, Manuel Reinhart, Sebastian A. Wohlfeil, Manuel Winkler, Christian David Schmid, Joerg Heineke, Cyrill Géraud, Sergij Goerdt, Philipp-Sebastian Reiners-Koch, Victor Olsavszky

“…The dynamic adaptations to the metabolic challenges of developing MASLD/MASH caused an early shift from the normal hepatic vascular niche to a pre-metastatic vascular niche that promoted hepatic melanoma metastasis in the context of cell-autonomous and acquired melanoma cell features. …”
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Preterm preeclampsia screening and prevention: a comprehensive approach to implementation in a real-world setting by Stefania Ronzoni, Shamim Rashid, Aimee Santoro, Elad Mei-Dan, Jon Barrett, Nanette Okun, Tianhua Huang

“…Methods A prospective cohort study involved pregnant individuals undergoing nuchal translucency scans between 11 and 14 weeks. …”
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Association between gestational weight gain and adverse pregnancy outcomes: cohort analysis from South Asia and Sub-Saharan Africa by Anisur Rahman, Fyezah Jehan, Gary M Shaw, Sunil Sazawal, Salahuddin Ahmed, Abdullah H Baqui, David K Stevenson, Monjur Rahman, Jesmin Pervin, Shaki Aktar, Rasheda Khanam, Sayedur Rahman, Nitya Wadhwa, Ge Zhang, Huan Xu, Usma Mehmood, Shinjini Bhatnagar, Jeffrey S A Stringer, Bellington Vwalika, Waqasuddin Khan, Nabidul Haque Chowdhury, Imran Nisar, Javairia Khalid, Nima Aghaeepour, U Tin Nu, Yuri V Sebastião, Ramachandran Thiruvengadam, Ayushi, Bapu Koundinya Desiraju, Fatma Kabole, Muhammad Farrukh Qazi, Margaret Kasaro, Bihila Abdalla Bakari

“…The risk of preterm birth (13%) increased with lower GWG Z-scores among underweight (adjusted risk ratio (ARR), 1.4; 95% CI, 1.1 to 1.9 for lowest Z-score group) and normal BMI participants (ARR, 1.1; 95% CI, 1.0 to 1.2). …”
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Establishing Normative Dynamic Postural Control Values in Elite Female Handball Players by Brice Picot, Jeanne Dury, Guillaume Néron, Patrick O McKeon, Nicolas Forestier

“…Means, standard deviations and 95% confidence intervals (95%CI) of normalized reached distances were calculated for each direction and the composite score (COMP). …”
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Persistently high concentrations of β-hydroxybutyrate affect hepatic SOD2 expression and blood SOD activity in high-yielding dairy cows by Dominika Grzybowska, Katarzyna Żarczyńska, Przemysław Sobiech, Paweł Brym, Dawid Tobolski

“…By week 7, hepatic SOD2 expression began to normalize, indicating a transient response or adaptation. …”
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Identification of CD8+ T Cell-Related Genes: Correlations with Immune Phenotypes and Outcomes of Liver Cancer by Qi Pan, Ying Cheng, Donghua Cheng

“…Using immunohistochemistry and single-cell sequencing analysis, we found that CD3D antibody staining was weaker in tumor tissues than normal tissues and was related to CD8+ T cells. Conclusion. …”
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Identification and Clinical Validation of High HSP60 Expression Predicts Poor Prognosis in Patients with Ovarian Cancer by Zheng M, Li S, Deng J, Huang C, Zhang H

“…Kaplan-Meier survival curves and Cox regression models were utilized to evaluate overall survival and disease-free survival.Results: HSP60 expression was significantly higher in ovarian cancer tissues compared to normal ovarian tissues. High HSP60 expression was associated with larger tumor size, advanced FIGO stage, and increased lymph node metastasis. …”
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Lightweight Detection and Counting of Maize Tassels in UAV RGB Images by Hang Yang, Jiaji Wu, Yi Lu, Yuning Huang, Pinwei Yang, Yurong Qian

“…In addition, we built a maize tassel detection and counting dataset (MTDC-VS) with various sunlight conditions (low, normal, and high sunlight), containing 22,997 real maize tassel targets. …”
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