Retrospective study of the frequency of diagnosing diffuse changes in the liver parenchyma according to the results of radiological studies by N.Yu. Ziuz, V.M. Bogomaz

“…During the statistical analysis of quantitative features, the distribution of indicators for normality was checked according to the Shapiro-Wilk test. …”
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Impact of Cyclosporine A on Cognitive Functions and Neuronal Oxidative Stress, Apoptosis and Inflammatory Markers in Rats by Awyed Batah Almutairi, Abdulaziz Arif A. Alshammari, Arshad Husain Rahmani, Ali Yousif Babiker, Long Chiau Ming, Maha A. Aldubayan, Ahmad H. Alhowail, Vasudevan Mani

“…Four groups of six rats each were treated with normal saline (control) or varying doses of CYP-A (20, 50, and 100 mg/kg). …”
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MiR-216a-3p inhibits the cytotoxicity of primary natural killer cells by Rowan Abdelbary, Rowan Abdelbary, Manon Ragheb, Manon Ragheb, Shereen A. El Sobky, Nagwa El-Badri, Nourhan Aboud, Ahmed Tawheed, Asmaa Gomaa, Mona Zidan, Ramy K. Aziz, Abd Elrahman Abouzid, Radwa Ayman Salah, Mohamed El-Kassas, Imam Waked, Ahmed Moustafa, Ahmed Moustafa, Injie Omar Fawzy, Nada El-Ekiaby, Ahmed Ihab Abdelaziz

“…After that, we performed an in silico analysis to understand the mechanistic regulation imposed by miR-216a-3p on NK cells to study its impact on one of its potential downstream targets.ResultsOur results have indicated that miR-216a-3p has higher expression in NK cells of patients with HCC, and simulating this elevated expression pattern via forcing miR-216a-3p expression in normal NK cells has negatively impacted the release of TNF- α, IFN- γ, GrB, and PRF. …”
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Interaction between Nuclear Receptor and Alpha-Adrenergic Agonist Subtypes in Metabolism and Systemic Hemodynamics of Spontaneously Hypertensive Rats by Sheryar Afzal, Munavvar Abdul Sattar, Ibrahim Albokhadaim, Ali Attiq, Mahmoud Kandeel, Aimi Syamima Abdul Manap, Sameer M. Alhojaily

“…However, they were gradually normalized by single drug treatments in all groups, and to a greater extent in the SHR + Irb + Adp group (P<0.05). …”
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Biliary atresia susceptibility gene EFEMP1 regulates extrahepatic bile duct elastic fiber formation and mechanics by Kapish Gupta, Jessica Llewellyn, Emilia Roberts, Chengyang Liu, Ali Naji, Richard K. Assoian, Rebecca G. Wells

“…Pressure myography showed that Efemp1+/- ducts have altered mechanics compared to control ducts, with Efemp1+/- ducts displaying significant stretch compared to controls (p = 0.0376); these changes in stretch are similar to those observed in elastase-treated vs. normal ducts (p <0.0001) and in neonatal ducts vs. adult ducts (p <0.0001). …”
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Investigating the Effect of Testosterone Supplement on Heart and Muscle Damage in Rats Applied with Swimming Exercise by Ömer Kulaksız, Sefa Lök

“…Since the data were convenient with the normal distribution, ANOVA test was applied for betweengroups comparison and Duncan test was used to identify from which group the difference was resulted. …”
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Diagnostic efficacy of dual-energy CT virtual non-calcium technique in the diagnosis of bone marrow edema of sacroiliac joints in ankylosing spondylitis by Hongyue Lu, Zhi Li, Ziheng Liang, Yuqi Liu

“…The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of visual qualitative assessment for BME by Physicians A and B were as follows: iliac facet [(92.5%, 88.6%, 88.1%, 92.9%, 90.5%), (90.0%, 90.9%, 90.0%, 90.9%, 90.5%)], sacral facet [(88.4%, 87.8%, 88.4%, 87.8%, 88.1%), (90.7%, 85.3%, 86.7%, 89.7%, 88.1%)].In terms of objective quantitative analysis, the CT values of the edematous areas on the iliac and sacral surfaces were (-41.4 ± 15.9) Hu and (-38.8 ± 19.7) Hu, respectively, while the CT values of normal bone marrow areas were (-79.6 ± 18.2) Hu and (-72.8 ± 14.8) Hu, respectively. …”
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Relationship Between a Heavy Rainfall and Gravity Wave in Sichuan Basin by Xu Yizhou, Li Guoping, Zhang Xiaoyu, Xie Xin, Dong Yuanchang

“…Therefore, favorable water vapor conditions in the Basin combined with the specific circulation characteristics make the main precipitation of this process not occur in the slope and mountain area in the south of the Basin as the normal mountain rainstorm, but under the combined influence of gravity wave transmission to the north and multiple systems in the middle and low levels, the belt rainstorm occurs in the plain and hilly areas of the central Sichuan Basin.…”
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Klotho enhances stability of chronic kidney disease atherosclerotic plaques by inhibiting GRK2/PLC-β-mediated endoplasmic reticulum stress in macrophages via modulation of the ROS/... by Zhe Li, Jing Li, Lin Li, Qian Wang, Qian Zhang, Ling Tian, Chenchen Li

“…This study investigates the mechanism by which Klotho enhances the stability of atherosclerotic plaques in chronic kidney disease. apoE-/- knockout mice and C57BL/6 mice underwent 5/6 nephrectomy and then klotho-NC and klotho-mimic groups were set up to be fed a high-fat chow diet and a dummy group was created to be fed a normal chow diet. qPCR detected relative mRNA expression of klotho. …”
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The Relationship Between the Upper-Body Strength Characteristics with Velocity and Power Parameters During the Bench Throw Movement: Is Sport Branch An Inportant Factor ? by Serdar Bayrakdaroğlu, İbrahim Can

“…To determine the velocity and power parameters, a bench throw (BT) movement was performed using an external load of 30 % of the participants' body weight and mean propulsive velocity (MPV), peak velocity (PV), mean propulsive power (MPP) and peak power (PP) by the help of an isoinertial velocity transducer (T-Force dynamic measurement system). Shapiro-Wilk normality test, descriptive statistics and Spearman correlation analysis methods were used to evaluate the data. …”
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Identification of biomarkers for knee osteoarthritis through clinical data and machine learning models by Wei Chen, Haotian Zheng, Binglin Ye, Tiefeng Guo, Yude Xu, Zhibin Fu, Xing Ji, Xiping Chai, Shenghua Li, Qiang Deng

“…Among these, age, plasma prothrombin time, gender, body mass index (BMI), and prothrombin time and international normalized ratio (PTINR) emerged as the top five features, with SHAP values of 0.1990, 0.0981, 0.0471, 0.0433, and 0.0422, respectively. …”
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Reliability of an Observational Biomechanical Analysis Tool in Adolescent Baseball Pitchers by Steven F DeFroda, Dai Sugimoto, Steven J Staffa, Donald S Bae, Ellen Shanley, Charles A Thigpen, Peter K Kriz

“…Total ACES scores ranged from 1 to 13, normally distributed. ACES total score demonstrated excellent intra-rater reliability within each rater (ICC for rater 1 = 0.99 (95% CI; 0.98, 0.99); ICC for rater 2 = 0.94; 95% CI: 0.84, 0.97); ICC for rater 3 = 0.98 (95% CI: 0.96, 0.99)). …”
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An Experimental Study on Mechanical Properties and Fracture Characteristics of Saturated Concrete under Coupling Effect of Low Temperature and Dynamic Load by Mengxiang Wang, Qi Zong, Haibo Wang

“…In order to study the mechanical properties and fracture characteristics of saturated concrete under the coupling effect of low temperature and dynamic load, the impact compression tests of concrete under normal temperature 20°C, -5°C, -10°C, and -15°C were carried out with a diameter of 74 mm split Hopkinson pressure bar (SHPB). …”
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Effects of the Highly COX-2-Selective Analgesic NSAID Etoricoxib on Human Periodontal Ligament Fibroblasts during Compressive Orthodontic Mechanical Strain by Christian Kirschneck, Erika Calvano Küchler, Michael Wolf, Gerrit Spanier, Peter Proff, Agnes Schröder

“…In this in vitro study, we investigated possible side effects of two clinically relevant etoricoxib concentrations on the expression pattern of mechanically strained hPDL fibroblasts and associated osteoclastogenesis in a model of simulated orthodontic compressive strain occurring during orthodontic tooth movement. hPDL fibroblasts were incubated for 72 h under physiological conditions with etoricoxib at 0 μM, 3.29 μM, and 5.49 μM, corresponding to clinically normal and subtoxic dosages, with and without mechanical strain by compression (2 g/cm2) for the final 48 h, simulating conditions during orthodontic tooth movement in compressive areas of the periodontal ligament. …”
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Examining the association of elevated initial serum lactate with mortality and morbidity in trauma patients: a retrospective study by Pablo Rodríguez-Ortiz, Kyara Berríos-Toledo, Ediel O. Ramos-Meléndez, Lourdes Guerrios-Rivera

“…Patients were classified as normal (4.5–19.8 mg/dL) or elevated (≥ 19.9 mg/dL) iSL levels. …”
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A Comparison of Resting Scapular Posture and the Davies Closed Kinetic Chain Upper Extremity Stability Test by John D Heick, Jenna Haggerty, Robert C Manske

“…The average number of CKUEST touches, a normalized score, and a power score were calculated for each participant. …”
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Extracellular Vesicles Released from Neprilysin Gene-Modified Human Umbilical Cord-Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an Alzheimer’s Disease Animal Model... by HyeJu Jeong, Ok Joon Kim, Seung-Hun Oh, Sanghoon Lee, Han A. Reum Lee, Kee Ook Lee, Boo-Yong Lee, Nam Keun Kim

“…We compared the differences in behavioral tests and immunohistochemical assays between four groups: normal, Aβ1-42 injection, naïve hUC-MSCs, and NEP-enhanced hUC-MSCs. …”
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Hypergammaglobulinemia in Hidradenitis Suppurativa Patients: A New Emerging Association by Martora F, Battista T, Giordano A, Potestio L, Megna M

“…Unlike older patients, where immunosenescence can lead to more normal gamma globulin levels, younger patients demonstrated a strong link between chronic inflammation and disease. …”
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Evaluation of mineral and near-infrared forecasting of wheat yield varieties using spectrophotometric techniques by H.A. Pardhe, N. Krishnaveni, B.K. Chekraverthy, S. Patel, S. Naveen, V. Rashmi, P.C. Govinden

“…The biofortified varieties (HI-8663 and HI-1605) were found to have high iron content when compared to normal wheat. The acquired results bridge the intricate relationship between plant-based diets, micronutrient deficiencies, providing valuable insights into combating iron deficiencies in public health with the potential achievement of improved nutritional understanding, optimized wheat selection, advanced analytical techniques, education, awareness, and iron deficiency mitigation.…”
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Brain iron deposition and cognitive decline in patients with cerebral small vessel disease : a quantitative susceptibility mapping study by Yian Gao, Changhu Liang, Qihao Zhang, Hangwei Zhuang, Chaofan Sui, Nan Zhang, Mengmeng Feng, Haotian Xin, Lingfei Guo, Yi Wang

“…Abstract Background Quantitative susceptibility mapping (QSM) can study the susceptibility values of brain tissue which allows for noninvasive examination of local brain iron levels in both normal and pathological conditions. Purpose Our study compares brain iron deposition in gray matter (GM) nuclei between cerebral small vessel disease (CSVD) patients and healthy controls (HCs), exploring factors that affect iron deposition and cognitive function. …”
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