Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival by Anna Darlene van der Heiden, Raphaela Pensch, Sophie Agger, Heather L. Gardner, William Hendricks, Victoria Zismann, Shukmei Wong, Natalia Briones, Bryce Turner, Karin Forsberg-Nilsson, Cheryl London, Kerstin Lindblad-Toh, Maja Louise Arendt

“…Our study aimed to characterize the mutational landscape of cDLBCL using whole-genome sequencing of matched tumor-normal samples obtained from a cohort of 43 dogs previously enrolled in a clinical trial for which longitudinal follow-up was available. …”
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Embryonic heat conditioning induces paternal heredity of immunological cross- tolerance: coordinative role of CpG DNA methylation and miR-200a regulation by Padma Malini Ravi, Tatiana Kisliouk, Shelly Druyan, Amit Haron, Mark A. Cline, Elizabeth R. Gilbert, Noam Meiri

“…Additionally, analysis of sperm methylation patterns in EHC mature chicks led to identification of genes associated with neuronal development and immune response, indicating potential neural network reorganization. Finally, miR-200a emerges as a regulator potentially involved in mediating the cross-tolerance effect.…”
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Novel machine learning-driven comparative analysis of CSP, STFT, and CSP-STFT fusion for EEG data classification across multiple meditation and non-meditation sessions in BCI pipel... by Nalinda D. Liyanagedera, Corinne A. Bareham, Heather Kempton, Hans W. Guesgen

“…While testing different feature extraction algorithms, a common neural network structure was used as the classification algorithm to compare the performance of the feature extraction algorithms. …”
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Col1A1 as a new decoder of clinical features and immune microenvironment in ovarian cancer by Xiao Xiao, Fangyi Long, Shaolan Yu, Wengjuan Wu, Dayan Nie, Xiaoyan Ren, Wen Li, Xujuan Wang, Ling Yu, Pinghan Wang, Gang Wang

“…The LinkedOmics and INPUT2 databases were used to analyze differential gene expression in OC, This was followed by enrichment analysis using the Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) annotations to identify and predict potential signaling pathways associated with COL1A1.ResultsOur study demonstrated that COL1A1 expression was significantly elevated in OC tissues compared to normal ovarian tissues. This elevated expression was closely associated with tumor metastasis, poor prognosis, and advanced pathological stages in OC patients. …”
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The mechanism of tea tree oil regulating the damage of hydrogen sulfide to spleen and intestine of chicken by Yachao Wang, Yilei Liang, Yan Huang, Wei wang, Xiaoyan Long, Li Jiang, Tingting Cheng, Jinfeng Du, Xuegang Luo

“…Compared with CON, TTO treatment alleviated serum biochemical disorders and intestinal damage caused by H2S exposure and restored them to normal (P > 0.05). In conclusion, TTO can improve spleen and intestinal function and reduce the effects of H2S on growth performance and health of chickens.…”
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Correlation and clinical significance of placental tissue selectin (E), angiotensin II and its receptors, and oxidized lipid levels in patients with preeclampsia by Yan Gao, Guohong Wu, Haiting Huang, Xiaoyan Lu, Peifen Wu, Zou Suiyi, Zhenyan Liu

“…Methods: Select 30 PE pregnant women who were admitted to our hospital from March 2023 to January 2024 as the case group, and select another 30 normal pregnant women who were registered in our hospital during the same period as the health group .The general information of the two groups and placental tissue selectin (E), plasma AngII, ATRs, placental tissue MDA, 8-iso-PGF2a and blood pressure levels (systolic blood pressure (SBP), diastolic blood pressure (DBP)) were compared. …”
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Spatiotemporal Parameters of Gait Among Adolescent Athletes with Concussion When Performing a Visuospatial Cognitive Task by Leah Lowe, Fernando Castillo, Melissa Allen, Michael Israel, Charlotte Yates

“…They walked at a self-selected speed along the 5.186-meter GAITRite® Walkway System with and without a concurrent visuospatial cognitive task presented on a hand-held tablet. Outcomes included normalized velocity (m/s), step length (m), and double limb (DLS) and single limb support (SLS) (defined as the percent of a gait cycle \[%GC\]). …”
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Newborn morbidities and care procedures at the special newborn care units of Gandaki Province, Nepal: a retrospective study by Khim Bahadur Khadka, Nabina Koirala, Olena Ivanova, Ramchandra Bastola, Dela Singh, Kamala Rana Magar, Bidhya Banstola, Ramesh Prasad Adhikari, Vincentas Giedraitis, Deepak Paudel, Guenter Froeschl

“…Underweight newborns had 8.8 times (CI: 4.5–17.2) higher risk of death than newborns with a normal birth weight, even after adjusting for other factors like sex, delivery site, mode of delivery, mother’s age, respiratory distress syndrome, neonatal hyperbilirubinemia, neonatal sepsis, and age at admission to SNCU. …”
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Application of iced tea lotion in oral care of middle-aged and elderly patients with diabetes mellitus (冰茶洗剂在中老年糖尿病患者口腔护理中的应用效果分析) by FENG Lifen (冯李芬), ZHANG Xiaolin (张晓琳)

“…They were randomly divided to control group (n=45) and observation group (n=45), and treated by oral care of normal saline and ice tea lotion, respectively. Oral malodor, swelling and congestion of oral mucosa and culture results of oral throat swab between groups were compared. …”
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Optical properties of polyvinyl alcohol-glass waste powder composites by Hani M. Hussien

“…The change of dielectric constant and refractive index with wavelength depends on the amount of the filler, where the pure and the sample filled with 10% glass powder show normal dispersion, while the other samples show anomalous dispersion. …”
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Impact of Immunotherapies on SARS-CoV-2-Infections and Other Respiratory Tract Infections during the COVID-19 Winter Season in IBD Patients by Constanze Heike Waggershauser, Cornelia Tillack-Schreiber, Paul Weyh, Eckard Alt, Thorsten Siegmund, Christine Berchthold-Benchieb, Daniel Szokodi, Fabian Schnitzler, Thomas Ochsenkühn

“…In our study, IBD patients are as susceptible to respiratory tract infections or SARS-CoV-2 as the normal population. There is no evidence of an association between IBD therapies and increased risk of COVID-19. …”
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Efficacy of uterine flushing with human chorionic gonadotropin (hCG) on pregnancy rates in primary unexplained infertility: a randomized controlled trial by Parvin Hakimi, Mahshid Alborzi, Ehsan Nikkhou, Hosein Azizi

“…The intervention group received 500 units of hCG diluted in 0.5 cc of normal saline and was injected into the uterine cavity along with the two intramuscular ampoules. …”
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Both CYP2C19 and PON1 Q192R Genotypes Influence Platelet Response to Clopidogrel by Thrombelastography in Patients with Acute Coronary Syndrome by Wenxing Peng, Xiujin Shi, Xiaoyu Xu, Yang Lin

“…The patients with <30% platelet inhibition were defined as HPR group, while the others were defined as normal platelet responsiveness (NPR) group. The genotypes distribution between the groups was assessed, and the clinical impact of genetic variants was investigated by comparing the relationship between the risk of HPR and genotypes including CYP2C19⁎2, CYP2C19⁎3, CYP2C19⁎17, ABCB1, and PON1. …”
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Gestational diabetes mellitus in previous pregnancy associated with the risk of large for gestational age and macrosomia in the second pregnancy by Ying Wang, Ying Wang, Ying Wang, Juan Yang, Juan Yang, Juan Yang, Yuzhen Liu, Yuzhen Liu, Yuzhen Liu, Ao Yang, Ao Yang, Ao Yang, Yuqing Deng, Yuqing Deng, Yuqing Deng, Chang Xu, Shilin Zhong, Shilin Zhong, Shilin Zhong

“…Among women without previous GDM, if the pre-pregnancy BMI is normal, the risk of LGA and macrosomia is significant lower in AGWG compared with EGWG (P&lt; 0.001), while this difference was no significant among women with prior GDM (P&gt;0.05).ConclusionPrevious GDM is strongly linked to LGA and macrosomia in subsequent pregnancies. …”
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Knowledge, Attitude, and Practice towards COVID-19 among Mothers in Dessie Town, Northeast Ethiopia, 2020 by Debrnesh Goshiye, Zinet Abegaz, Sisay Gedamu

“…Coronavirus disease 2019 (COVID-19) is a highly infectious disease causing a catastrophic effect, and many of us are worried to find a new normal. Many burdens are occurring in households, predominantly to women and mothers. …”
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Prospective Study of Posterior Cervical Foraminotomy for Cervical Radiculopathy in Absenceof Myelopathy by Umesh D. Jain, Amol Gowaikar, Pradip Patil, Uday Ghate, Rishabh Nair

“…Results: When we analyzed the NDI scores at different intervals there has been a positive trend showing the improvement in overall well being of an individual patient and this has resulted in major porting of the patients that has been taken as a sample has returned to there normal day to day living which they used to have earlier, before suffering from cervical radiculopathy. …”
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The Role of Autophagy in Copper-Induced Apoptosis and Developmental Neurotoxicity in SH-SY5Y Cells by Lu Lu, Ying Zhang, Wei Shi, Qian Zhou, Zhuoqi Lai, Yuepu Pu, Lihong Yin

“…The results showed that copper resulted in the reduction and shortening of neural synapses in differentiated cultured SH-SY5Y cells, a downregulated Wnt signaling pathway, and nuclear translocation of β-catenin. …”
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Clinical characteristics of Kawasaki disease with pulmonary radiographic abnormalities and its impact on the incidence of coronary artery lesions: a randomized retrospective cohort... by Chenchen Liu, Xing Rong, Huixian Qiu, Jinhui Zhou, Yufei Chen, Xuhong Huang, Maoping Chu, Zhenquan Wang

“…ObjectiveThe aim of this study was to investigate the characteristics of Kawasaki disease (KD) in patients demonstrating pneumonia-like changes and pulmonary complications, as well as the subsequent impact on coronary artery lesions, by comparing them with those of KD patients with normal pulmonary imaging.MethodFrom January 1, 2013 to October 1, 2022, this study included paediatric patients diagnosed with KD who were registered in the KD database at Yuying Children's Hospital affiliated with Wenzhou Medical University. …”
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Application of WeChat-based cognitive behavioural stress management for early-stage cervical cancer patients: a randomised controlled study by Qing Hao, Lan Feng, Dandan Chen, Xia Fan, Lei Wei, Zhaojun Cui, Jing Zhang, Lin Wang, Dan Zhang, Xinxin Zhan, Wenping Yang

“…Background This randomised controlled study was aimed at investigating the effects of WeChat-based cognitive behavioural stress management (WB-CBSM) on the mental health of patients with early-stage cervical cancer treated with surgical resection.Methods A total of 184 patients with early-stage cervical cancer were randomised to receive either WB-CBSM (n = 92) or normal care (NC) (n = 92) for 8 weeks.Results Compared with the NC group, the WB-CBSM group exhibited reduced Hospital Anxiety and Depression Scale (HADS)–anxiety scores at months (M)1 (t = 2.022, P = 0.045), M3 (t = 2.575, P = 0.011), and M6 (t = 2.709, P = 0.007); anxiety rates at M3 (χ2 = 4.834, P = 0.028) and M6 (χ2 = 5.182, P = 0.023); HADS–depression scores at M3 (t = 2.069, P = 0.040) and M6 (t = 2.449, P = 0.015); and depression rates at M6 (χ2 = 4.268, P = 0.039). …”
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Liver fibrosis stage classification in stacked microvascular images based on deep learning by Daisuke Miura, Hiromi Suenaga, Rino Hiwatashi, Shingo Mabu

“…Methods This single-center, cross-sectional study included 517 patients with CLD who underwent ultrasonography and liver stiffness testing between August 2019 and October 2022. A convolutional neural network model was constructed to evaluate the degree of liver fibrosis from stacked microvascular images generated by accumulating high-sensitivity Doppler (i.e., high-definition color) images from these patients. …”
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