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Use of Nucleic Acid Analogs for the Study of Nucleic Acid Interactions
Published 2011-01-01“…Remarkably, they can adopt two different conformations responding to their interaction energies, and one of them is the stacking conformation of the nonpolar aromatic group causing the site-selective flipping of the opposite base in a DNA double helix. The base pair-mimic nucleosides can be used to study the mechanism responsible for the base stacking and the flipping of bases out of a nucleic acid duplex.…”
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Application of ectoine in diseases of the skin and mucous membranes
Published 2024-06-01“…It has been shown to have a positive effect on the stability of DNA helix, increases the temperature resistance of DNA polymerase, and lowers the melting temperature of the double-stranded DNA. …”
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