Assessing the feasibility of measuring residents’ quality of life in English care homes and the construct validity and internal consistency of measures completed by staff proxy: a... by Claire Goodman, Julienne Meyer, Karen Spilsbury, Barbara Hanratty, Rachael Carroll, Adam L Gordon, Gizdem Akdur, Anne Killett, Jennifer Burton, Ann-Marie Towers, Stacey Rand, Nick Smith, Sinead Palmer, Stephen Allan, Lucy Anne Webster

“…Objectives To assess the feasibility of capturing older care home residents’ quality of life (QoL) in digital social care records and the construct validity (hypothesis testing) and internal consistency (Cronbach’s alpha) of four QoL measures.Design Cross-sectional data collected in wave 1 of the DACHA (Developing resources And minimum dataset for Care Homes’ Adoption) study, a mixed-methods pilot of a prototype minimum dataset (MDS).Setting Care homes (with or without nursing) registered to provide care for older adults (>65 years) and/or those living with dementia. …”
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Treating drug-resistant tuberculosis in an era of shorter regimens: Insights from rural South Africa by J-D K Lotz, J Porter, H Conradie, T Boyles, B Gaunt, S Dimanda, D Cort

“…Amidst these, a shorter regimen was introduced in 2017 with weak evidence, and has shown mixed results. Outcomes still fall short of national targets, and the coronavirus disease 2019 pandemic has undermined progress to date. …”
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Preparation of future teachers for innovative activities in pedagogical and technological educational environment by N. I. Naumkin, N. N. Shekshaeva, V. F. Kupryashkin, E. V. Zabrodina

“…Such methodological system provides the implementation of mixed, project, “inverted” and other methods of teaching innovation in the basis of integrated, convergent, environmental and other approaches to learning.Results and scientific novelty. …”
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Feasibility and usefulness of Gini coefficients of primary care visits as a measure of service inequality: preliminary findings from a cross-sectional study using region-wide elect... by Xin Yang, Jing Chai, Jing Cheng, DeBin Wang, XingRong Shen, Rong Liu, ManMan Lu, Jia Xu, Ningjing Yang, Guocheng Li

“…Then it developed logarithmic models of GPVs using different months of records and performed descriptive and generalised linear mixed-effects regression analyses of the GPVs for all-cause diseases. …”
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Reactive agility training to prevent frailty in older adults – a randomized controlled trial. by Eric Lichtenstein, Martin Keller, Ralf Roth, Sebastian Ludyga, Oliver Faude

“…Data analysis was performed using linear mixed-effects models, examining group×time interactions standardized to baseline standard deviation. …”
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Process evaluation of Project Daire: a food environment intervention that impacted food knowledge, wellbeing and dietary habits of primary school children by Naomi Anderson, Sarah F. Brennan, Fiona Lavelle, Sarah E. Moore, Dilara Olgacher, Amy Junkin, Moira Dean, Michelle C. McKinley, Patrick McCole, Ruth F. Hunter, Laura Dunne, Niamh E. O’Connell, Chris T. Elliott, Danielle McCarthy, Jayne V. Woodside

“…Nourish schools delivered a higher mean dose of intervention elements (61.4%) than Engage (50%) schools but, overall, mixed implementation of both interventions occurred. …”
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Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Ra... by Yolanda López-del-Hoyo, Selene Fernández-Martínez, Adrian Perez-Aranda, Alicia Monreal-Bartolomé, Alberto Barceló-Soler, Loreto Camarero-Grados, Carilene Armas-Landaeta, José Guzmán-Parra, Vera Carbonell, Daniel Campos, Xinyuan Chen, Javier García-Campayo

“…Intracluster analysis revealed that pre- versus postintervention moderate effects were present in 2 clusters (Cohen d=0.46 and 0.62), and these were maintained in subsequent assessments. The linear mixed-effects models also showed that depression, anxiety, and somatization, as well as resilience, self-compassion, and some mindfulness facets, experienced significant improvements (P<.05) when comparing the intervention and control phases. …”
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Waste marble sludge and calcined clay brick powders in conventional cement farina production for cleaner built environment by Mehmet Serkan Kırgız, Jamal Khatib, Andre Gustavo de Sousa Galdino, Said Kenai, Ahmed Ashteyat, Raul D.S.G. Campilho, Roberto Alonso Gonzalez Lezcano, Gideon Olukunle Bamigboye, N. Nagaprasad, Krishnaraj Ramaswamy

“…Besides, to evaluate pozzolanic activity, the construction lime was mixed with the marble and brick wastes. The microstructure of the marble and brick waste was analyzed using X-ray fluorescence, scanning electron microscopy and energy dispersive spectroscopy. …”
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Theoretical and applied research on hydraulic slit-fracture joint roof control and pressure relief of hard roof in goaf roadway by Yongjiang ZHANG, Fei JI, Tongbin ZHAO, Ke YANG, Wenbin WU, Wangang JIANG

“…Through the abrasive jet ultra-high-pressure hydraulic slitting technology, the slots are preset in the hard top plate, which can play a guiding role for the hydraulic fracturing cracks to drag and expand, and increase the influence range of hydraulic fracturing cracks by opening up the original cracks in the rock body, forming a continuous weak surface in a hard roof to weaken the stress transmission of the roof, and the depth of the slits is positively correlated with the slit pressure and the sand mixing ratio. The roof strata will interact with each other during the collapse process, and the changes in fracture angle and height will lead to changes in the sliding speed of the fractured rock mass and significant differences in the support force of the high-level rock strata. …”
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Analysis of early effects of human APOE isoforms on Alzheimer’s disease and type III hyperlipoproteinemia pathways using knock-in rat models with humanized APP and APOE by Metin Yesiltepe, Tao Yin, Marc Tambini, Hanmei Bao, Meixia Pan, Cristina d’Abramo, Luca Giliberto, Xianlin Han, Luciano D’Adamio

“…APOE2 is linked to Hyperlipoproteinemia type III (HLP), characterized by mixed hypercholesterolemia and hypertriglyceridemia due to impaired binding to Low-Density Lipoproteins receptors. …”
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High-Throughput Phenotyping for Agronomic Traits in Cassava Using Aerial Imaging by José Henrique Bernardino Nascimento, Diego Fernando Marmolejo Cortes, Luciano Rogerio Braatz de Andrade, Rodrigo Bezerra de Araújo Gallis, Ricardo Luis Barbosa, Eder Jorge de Oliveira

“…Various VIs were obtained and analyzed using mixed models to derive the best linear unbiased predictors, heritability parameters, and correlations with various agronomic traits. …”
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To what extent does the CO₂ diurnal cycle impact flux estimates derived from global and regional inversions? by S. Munassar, S. Munassar, S. Munassar, C. Rödenbeck, M. Gałkowski, M. Gałkowski, F.-T. Koch, F.-T. Koch, K. U. Totsche, K. U. Totsche, S. Botía, C. Gerbig

“…Differences between CO<span class="inline-formula">₂</span> mixing ratios simulated with daily averaged and hourly NEE from FLUXCOM-X range between around <span class="inline-formula">−</span>2.5 and 7 ppm averaged annually throughout a site network across the world. …”
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Characteristics and prognostic factors of chronic kidney disease patients with Pneumocystis jirovecii pneumonia by Liu Xiao-hua, Wu Jing-jing, Zeng Ming, Ge Yi-fei, Zhang Bo, Wu Bu-yun, Mao Hui-juan

“…All patients had a history of glucocorticoids or immunosuppressants use 3 months prior to PJP. CT findings included mixed ground-glass opacities type and nodular type （81.8%）. …”
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Acceptability, feasibility, and effectiveness of internet-based cognitive behavior therapy for obsessive–compulsive disorder (OCD-NET): a naturalistic pilot trial during the COVID-... by Elisabeth Kohls, Sabrina Baldofski, Julia Scholl, Oskar Flygare, Lina Lundström, Ursula Beyrich-Kolbus, Marc Steinbrecher, Christian Rück, Christine Rummel-Kluge

“…Satisfaction with the program was high, with a majority of participants indicating that they would recommend it to others (n = 56, 98.2%) and that it provided the support they needed (n = 49, 86.0%).Mixed-effect models showed a significant reduction in OCD symptoms (OCI-R), with large within-group effect sizes in both intention-to-treat (ITT) and completer analyses. …”
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Work performance, physiological and hemato-biochemical responses in working buffalo with different load weights by Visoky Paján-Jiménez, Fernando D. Pazmiño-Rodríguez, Patricia Roldán-Santiago, Cristian Larrondo-Cornejo, Anna Dutro-Aceves, Luis A. de la Cruz-Cruz

“…All variables were compared with a mixed model for repeated measures, considering the factors time and load weight and Time x Load weight interactions as fixed effects, with the animal in each group as a random effect. …”
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Clozapine for Treatment-Resistant Disruptive Behaviors in Youths With Autism Spectrum Disorder Aged 10-17 Years: Protocol for an Open-Label Trial by André Luiz Schuh Teixeira da Rosa, Marina Ribeiro Barreto da Costa, Gabriela Bezerra Sorato, Felipe de Moura Manjabosco, Érica Bonganhi de Bem, Lucas Dellazari, Arthur Bezerra Falcão, Lucas de Oliveira Cia, Olivia Sorato Bezerra, Rogério Boff Borges, Luis Augusto Rohde, Ana Soledade Graeff-Martins

“…Statistical analysis will include chi-square tests with Monte Carlo simulation for categorical variables, paired t tests or Wilcoxon tests for continuous variables, and multivariate linear mixed models to evaluate the primary outcome, adjusting for confounders. …”
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O debate entre cosmopolitismo, patriotismo e nacionalismo: uma introdução geral ao tema by Mariane Gehlen Perin

“…Cosmopolitanism, with its origin in Ancient Greece with Diogenes of Sinope, was preserved within the stoic doctrine and got mixed in the course of history with other familiar currents, namely universalism and internationalism. …”
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NaHS alleviates neuropathic pain in mice by inhibiting IL-17-mediated dopamine (DA) neuron necroptosis in the VTA by Jun Wang, Nan Zhang, Hong-Zheng Liu, Jin-Liang Wang, Yong-Bo Zhang, Dong-Dong Su, Li-Min Zhang, Bao-Dong Li, Hui-Tao Miao, Jun Miao

“…It has been revealed that inflammatory activation triggers necroptosis by stimulating mixed lineage kinase domain-like protein (MLKL), leading to progressive neuronal demise. …”
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Lactational performance effects of 3-nitrooxypropanol supplementation to dairy cows: A meta-regression by L.F. Martins, M. Maigaard, M. Johansen, P. Lund, X. Ma, M. Niu, A.N. Hristov

“…Dose (± SD; 77.0 ± 33.17 mg 3-NOP/kg DMI), forage-to-concentrate ratio (FC; 58.9 ± 8.83%, expressed as average ± SD% of forage in the diet), dietary concentrations of CP, ether extract, NDF, and starch (16.3 ± 1.84%, 4.3 ± 1.03%, 33.7 ± 4.40%, and 20.9 ± 3.97%, as average ± SD% of DM, respectively), supplementation length (days), and DIM and BW of the cows at the beginning of the study were used as continuous explanatory variables. Mixed-effects models were fitted using the robust variance estimation method. …”
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Investigating the Efficacy of the Web-Based Common Elements Toolbox (COMET) Single-Session Interventions in Improving UK University Student Well-Being: Randomized Controlled Trial by Jeffrey Lambert, Maria Loades, Noah Marshall, Nina Higson-Sweeney, Stella Chan, Arif Mahmud, Victoria Pile, Ananya Maity, Helena Adam, Beatrice Sung, Melanie Luximon, Keren MacLennan, Clio Berry, Paul Chadwick

“…The data were analyzed using linear mixed models and reported in accordance with the CONSORT-EHEALTH (Consolidated Standards of Reporting Trials of Electronic and Mobile Health Applications and Online Telehealth) checklist. …”
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