Plasma S100β is a predictor for pathology and cognitive decline in Alzheimer’s disease by Geetika Nehra, Bryan J. Maloney, Rebecca R. Smith, Wijitra Chumboatong, Erin L. Abner, Peter T. Nelson, Björn Bauer, Anika M. S. Hartz

“…All outcomes were assessed for linear associations with global cognitive function (MMSE, CDR) and cerebral atrophy scores by Pearson, polyserial, or polychoric correlation, as appropriate, along with generalized linear modeling or generalized linear mixed-level modeling. Results As expected, we detected elevated Aβ and tau pathology in brain tissue sections from AD patients compared to CNI. …”
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External beam radiation therapy versus radical prostatectomy for high-risk prostate cancer: protocol of the RECOVER study by Caroline M. van der Starre, Chris H. Bangma, Maarten J. Bijlsma, Alfons C.M. van den Bergh, Lambertus A.L.M. Kiemeney, Wietske Kievit, Kees Vos, Diederik M. Somford, Sally M. Wildeman, Katja K.H. Aben, Igle J. de Jong, Floris J. Pos, Berdine L. Heesterman

“…Descriptive statistics and mixed-effects models are used to assess differences in HRQoL and functional outcomes over time between the patients treated with radical prostatectomy versus EBRT (+ ADT). …”
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Levodopa Challenge Test Predicts STN-DBS Outcomes in Various Parkinson’s Disease Motor Subtypes: A More Accurate Judgment by Zijian Zheng, Zixiao Yin, Bohan Zhang, Houyou Fan, Dan Liu, Yuancheng Zhou, Jian Duan, Dongwei Zhou, Xi Wu, Guohui Lu

“…Patients were classified into tremor-dominant (TD), akinetic-rigid-dominant (AR), and mixed (MX) groups. Clinically important difference (CID) was employed to dichotomize DBS effects. …”
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Comprehensive overview of genotype distribution and prevalence of human papillomavirus in cervical lesions by Yang Liu, Chengquan Zhao, Tiannan Wang, Yuhong Ye, Terrel Jones, Xianxu Zeng

“…The distribution of HR-HPV in severe squamous lesions is complex, involving many HR-HPV genotypes in addition to HPV16, while the distribution of HR-HPV genotypes in endocervical glandular lesions is mainly limited in HPV18 and HPV16.Large datasets from China have identified the three most common HR-HPV genotypes in this population as stratified by diagnostic category: HPV52, HPV16, HPV58 in histologically negative cases and cervical intraepithelial neoplasia 1 (CIN1); HPV16, HPV52, HPV58 in CIN2/3; HPV16, HPV58, HPV52 or HPV18 in squamous cell carcinoma (SCC); HPV16, HPV18 and HPV52 in endocervical adenocarcinoma in situ (AIS), invasive adenocarcinoma, as well as mixed squamous and glandular lesions. HPV33 is the fourth most common HPV type in CIN2/3 and SCC, while HPV45 occurs more commonly in AIS and adenocarcinoma, compared with squamous lesions. …”
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ASPEK RUANG SEBAGAI LANDASAN PEMILIHAN RUANG DI TEPI LAUT SENGGOL by Muhammad Uliah Shafar, Wijayanti

“…This research method is mixed-method. While, this research design is cross-sectional using cross tabulation and biplot image analysis. …”
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Betulinic Acid Inhibits the Metastasis of Colon Cancer Cells through Regulating TGF-β/Smad Signaling Pathway by Xiaoying LIN, Aling SHEN, Meizhu WU, Ying CHENG, Xiaoping CHEN, Huixin LIU, Liya LIU, Zhiqing SHEN, Xiangyan WU, Nanhui XU, Jianfeng CHU, Youqin CHEN, Jun PENG

“…Objective:To explore the effect of betulinic acid (BA) on the growth and metastasis of colon cancer cell line HCT116 and the underlying possible mechanism.Methods:HCT116 cells were cultured with McCoy's 5A medium containing 10%fetal bovine serum and 1%penicillin/streptomycin mixed solution in a 37℃,5%CO₂incubator. …”
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The Effects of Exercise on Inhibitory Function Interventions for Patients With Major Depressive Disorder (MDD): A Systematic Review and Meta‐Analysis by Zhihui Xu, Cong Liu, Peng Wang, Xing Wang, Yuzhang Li

“…Regarding exercise elements, other types of exercise (resistance exercise RE, mixed exercise ME), duration greater than 45 min, intervention period of ≤12 weeks, frequency of two times per week, and low intensity were found to be more effective, all with statistical significance (SMD = 0.863, p < 0.001; SMD = 0.936, p < 0.001; SMD = 0.525, p = 0.002; SMD = 0.682, p = 0.004; SMD = 0.94, p = 0.00). …”
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Dietary fiber source and stage of gestation impact water balance, fecal physicochemical properties, serum electrolytes, and markers of gut motility in sows by Thomas A. Crome, Kyle D. Vahlenkamp, Rachel M. Self, Mark A. Giesemann, Amy L. Petry

“…Data were analyzed using a linear mixed model, with parity as a random effect and fiber, enzyme, period, and their interactions as fixed effects. …”
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Immune response and growth performance of crayfish Cherax quadricarinatus fed with supplementary diet of synbiotic by Amrullah Amrullah, Wahidah Wahidah

“…The experimental diets were formulated in three levels of synbiotic: the probiotic bacteria Micrococcus spp+100 mg/L alginate (Syn100), Micrococcus spp+200 mg/L alginate (Syn200), Micrococcus spp+300 mg/L alginate (Syn300), each level was mixed with tested feed. The basal diet (without synbiotics) served as the control diet. …”
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Utilization of Phosphogypsum and Sediment in Subgrade Material for Pavement Construction by Dragana Tomašević Pilipović, Nataša Slijepčević, Dunja Rađenović Veselić, Miloš Šešlija, Vesna Bulatović, Nataša Duduković

“…This study provides valuable insights into the physico-chemical and physico-mechanical properties of pavement mixes incorporating PG and sediment, supporting the feasibility of using these alternative materials in sustainable subgrade material for pavement construction and offering a viable solution to mitigate waste generation while enhancing pavement performance.…”
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Quality of life among residents of informal urban settlements during the COVID-19 pandemic in Salvador, Brazil by Albert I Ko, Federico Costa, Hammed Mogaji, Nivison Nery, Hernan D Argibay, Jaqueline S Cruz, Ianei O Carneiro, Ricardo Lustosa, Mike Begon, Hussein Khalil

“…We describe the HRQOL of residents, explored participants’ perception about the pandemic, and the relationship between sociodemographic, economic and employment data on physical and mental health scores using both χ2 statistics and separate mixed-effects regression models.Results Most participants were female (58.9%), aged 18–45 years (45%), with nearly half (49.7%) employed before pandemic, of whom 38.8% lost jobs during the pandemic. …”
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Use of Augmented Reality for Training Assistance in Laparoscopic Surgery: Scoping Literature Review by Francisco Javier Celdrán, Javier Jiménez-Ruescas, Carlos Lobato, Lucía Salazar, Juan Alberto Sánchez-Margallo, Francisco M Sánchez-Margallo, Pascual González

“…Surgical training has evolved from traditional approaches to the use of immersive digital technologies such as virtual, augmented, and mixed reality. These technologies are now integral to laparoscopic surgery training. …”
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Effectiveness of Video Teletherapy in Treating Obsessive-Compulsive Disorder in Children and Adolescents With Exposure and Response Prevention: Retrospective Longitudinal Observati... by Jamie D Feusner, Nicholas R Farrell, Mia Nunez, Nicholas Lume, Catherine W MacDonald, Patrick B McGrath, Larry Trusky, Stephen Smith, Andreas Rhode

“…We analyzed longitudinal outcomes of OCD symptoms, depression, anxiety, and stress using linear mixed models. ResultsTreatment resulted in a median 38.46% (IQR 12.50%-64.00%) decrease in OCD symptoms at 13-17 weeks, and 53.4% of youth met full response criteria at this point. …”
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A first study on sperm sexing in water buffalo through magnetic nanoparticles by Syed Murtaza Hassan Andrabi, Muhammad Hammad Fayyaz, Muhammad Shafiq Haider, Ghulam Muhammad Ali

“…Each tube containing sperm-MNPs suspension was slowly shaken for 5 minutes for uniform mixing. The MNPs were negatively charged and (provided by Clemente Associates Inc, Prescott, Arizona, USA) had a diameter of 50 nanometers. …”
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Rehabilitation success and related costs following stroke in a regional hospital: a retrospective analysis based on the Australian National Subacute and Non-Acute Patient (AN-SNAP)... by Fan He, George Mnatzaganian, Michael Njovu, David Rutherford, Tara Alexander, Irene Blackberry

“…Rehabilitation success was defined as relative functional gain (RFG) ≥ 0.5 and Functional Independence Measure (FIM) efficiency ≥ 1. Multivariate mixed effects logistical regressions modelled the sociodemographic and medical (i.e., comorbidities and stroke type) predictors of rehabilitation success, while logarithms of average daily and total rehabilitation payments were modelled using robust regressions. …”
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The Forgotten Hemodynamic (PCO2 Gap) in Severe Sepsis by Zouheir Ibrahim Bitar, Ossama Sajeh Maadarani, AlAsmar Mohammed El-Shably, Ragab Desouky Elshabasy, Tamer Mohamed Zaalouk

“…We performed a prospective observational study and recruited 28 patients with severe sepsis and septic shock in a mixed ICU. We determined central venous PO2, PCO2, PCO2 gap, lactate, and CI at 0 and 6 hours after critical care unit (CCU) admission. …”
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Provide a Framework for the Application of Open Policy Making in Parliament of Iran by Mohsen Eynali, Seyed Abbas Ebrahimi, Mohsen Farhadinejad, Hasan Danaeefard

“…Within this framework, the current research is specifically focused on developing a comprehensive open policy framework tailored for the Parliament of Iran, aiming to modernize and improve its policy-making processesMethodsThis research is grounded in the interpretative paradigm of the philosophical foundations of research and is applied in nature. It utilizes a mixed-methods approach for data collection. The target population encompasses all scientific experts in public policy (including faculty members of universities and research institutions with expertise in decision-making and public policy) and executive experts (including current and former members of the Parliament). …”
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Self-Management Strategies for Low Back Pain Among Horticulture Workers: Protocol for a Type II Hybrid Effectiveness-Implementation Study by Kim Dunleavy, Heidi Liss Radunovich, Jason M Beneciuk, Boyi Hu, Yang Yang, Janeen McCormick Blythe, Kelly K Gurka

“…We will also identify contextual factors impacting effectiveness and implementation. MethodsA pragmatic, mixed methods, hybrid effectiveness and implementation design will be used to compare back pain with work tasks, disability, medication and substance use, and psychological factors between a baseline control and intervention periods. …”
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Ketamine Infusion as an Adjunct to Opioid Analgesia in Pediatric Patients with High-Risk Neuroblastoma Undergoing Treatment with Dinutuximab: Adverse Effects and Safety in a Non-IC... by Streby KA, Tobias JD, McPhaden E, Downie S, Stanek J, Roth C, Patel PO

“…Demographics, pain scores, medication records, and total daily IV morphine milligram equivalents (IVMME) with and without a ketamine adjunct were collected. Linear mixed effect regression was used to model IVMME use for pain management across dinutuximab cycles and explore the effect of ketamine.Results: The study cohort included 187 dinutuximab hospitalizations from 40 patients. …”
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A randomized controlled, trial on effects of mobile phone text messaging in combination with motivational interviewing versus standard infant feeding counselling on breastfeeding a... by Moleen Zunza, Lehana Thabane, Louise Kuhn, Christine Els, Carl Lombard, Mark F. Cotton, Taryn Young

“…HIV services should reliably offer cART, consistently monitor viral load, and support mothers cART adherence, in settings where mixed feeding is common. Trial registration The trial was registered on ClinicalTrials.gov (NCT05063240) and Pan African Clinical Trial Registries (PACTR202110870407786) before recruitment of the first subject.…”
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