Physicochemical and functional optimization of probiotic yogurt with encapsulated Lacticaseibacillus paracasei E1 enriched with green tea using Box–Behnken design by Muhaimin Rifa'i, Mochammad Fitri Atho'illah, Siti Nur Arifah, Aditya Ragil Suharto, Aghnia Nuri Fadhilla, Nur Alfi Maghfirotus Sa'adah, Esha Ardiansyah, Rahmi Izati, Belinda Nabiila Al Faizah, Dawama Nur Fadlilah, Septhyanti Aprilia Kavitarna, Shinta Oktya Wardhani, Wisnu Barlianto, Hideo Tsuboi, Yoga Dwi Jatmiko

“…Green tea (GT) has many positive impacts on health and greater flexibility when mixed in various systems without losing its antioxidant properties. …”
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Rapid Verbal Persuasion to increase influenza vaccine uptake: protocol for a randomized hybrid type 2 effectiveness -implementation trial by Siyuan Liu, Lan Gao, Yingying Jin, Jiangyun Chen, Dadong Wu, Yiyuan Cai, Tao Wang, Sanhao Huang, Ciling Yan, Run Wang, Dong Roman Xu

“…Modified Poisson regression models and generalized linear mixed-effects models will be utilized to analyze the association between primary outcomes and interventions. …”
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Air pollution Dynamics: The role of meteorological factors in PM10 concentration patterns across urban areas by Carolina Girotti, Luiz Fernando Kowalski, Tiago Silva, Ezequiel Correia, Alessandra R. Prata Shimomura, Fernando Akira Kurokawa, António Lopes

“…The Factorial Analysis of Mixed Data method identified qualitative variables linked to the seasons, wind direction, and presence of trees. …”
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Baseline liver fibrosis-4 score correlates to the progression of anxiety and cognitive impairment in patients with Parkinson’s disease by Yongqing Cheng, Yongqing Cheng, Li Chen, Honghong Zhu, Yingchao Ge, Lei Li, Yan Guo, Xin Wang, Shuangfei You, Guojun He, Shouru Xue

“…Differences in the progression of clinical scales over five years were compared using generalized linear mixed models (GLMM).ResultsBaseline FIB-4 levels positively correlated to scores of baseline section III of the Unified-Parkinson Disease Rating Scale (UPDRS III) (r = 0.145, p = 0.017), Epworth Sleepiness Scale (EPSS) (r = 0.140, P = 0.022), Hopkins Verbal Learning Test (HVLT)-delayed recall (r = 0.128, P = 0.036) and HVLT-retention (r = 0.128, p = 0.036). …”
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Twelve-Month Retention in and Impact of Enhance®Fitness on Older Adults in Hawai‘i by Michiyo Tomioka, Kathryn L. Braun, Yan Yan Wu, Kay Holt, Paula Keele, Lori Tsuhako, Johnny Yago

“…This study examined 12-month participation in and impact of Enhance®Fitness on physical performance among older adults in Hawai‘i. Method. Linear mixed-effects models were applied to analyze the physical performance measures (chair-stands, arm curls, and the up-and-go test) collected at baseline (month 0) and at 4, 8, and 12 months. …”
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“It's hard to talk to a computer, I get it”: An exploratory analysis of clinician connection-building communication practices in rural telepalliative care encounters by Elise C. Tarbi, Natalie Ambrose, Eric C. Anderson, Rebecca N. Hutchinson, Paul K.J. Han, Maija Reblin, Robert Gramling

“…Methods: We analyzed data from the Northern New England Palliative Care TeleConsult Research Study – a formative mixed-methods pilot study at two academic medical centers in rural US states with patients with serious illness (2019–2020). …”
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The Effect of Intravascular Imaging-Guided Percutaneous Coronary Intervention on Coronary Artery Perforation by Yuichi Sawayama, MD, Kenta Sasaki, MD, Narumi Taninobu, MD, Akihiro Ikuta, MD, Kohei Osakada, MD, Shunsuke Kubo, MD, Takeshi Tada, MD, Yasushi Fuku, MD, Hiroyuki Tanaka, MD, Yoshihisa Nakagawa, MD, Kazushige Kadota, MD

“…We evaluated the trend of IVI-guided PCI and the incidence of CAP. A mixed effects logistic model was employed to assess their relationship. …”
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EGR1 mRNA expression levels and polymorphisms are associated with slaughter performance in chickens by Mao Ye, Xiaohuan Chao, Chutian Ye, Lijin Guo, Zhexia Fan, Xuerong Ma, Aijun Liu, Weiming Liang, Shuya Chen, Cheng Fang, Xiquan Zhang, Qingbin Luo

“…In addition, we explored the relationship between the EGR1 gene polymorphisms and slaughter traits using mixed linear models for the first time. In a population of Jiangfeng M3 lineage partridge chickens, we identified 4 EGR1 single-nucleotide polymorphisms, 2 of which were significantly associated with slaughter traits, including live weight, slaughter weight, semi-eviscerated weight, eviscerated weight, leg weight, wing weight, and breast muscle rate. …”
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Application of trichloroisocyanuric acid in controlling kiwifruit bacterial canker disease demonstrates its promising potential as an eco-friendly bactericide by Jianyou Gao, Jiewei Li, Cuixia Liu, Hongjuan Gong, Beibei Qi, Rongxiang Zhu, Liming Xia, Li Li, Shibiao Liu, Qiaosheng Jiang, Kaiyu Ye, Faming Wang

“…Our results demonstrate that TCCA effectively inhibits Psa growth in vitro, even at low concentrations, with minimum inhibitory concentrations (MICs) of 20 mg/L (TCCA added directly to the Psa suspension) and 100 mg/L (Psa cells mixed with liquid LB medium before adding TCC). In vivo, TCCA treatment at a concentration of 500 mg/L substantially reduced Psa colonization on both kiwifruit leaves and canes, outperforming conventional bactericides such as copper hydroxide, chlorothalonil, and ethylicin, as well as alternative treatments like pyraclostrobin-dysonline and Xinjunan acetate. …”
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Growth dynamics of Indian infants using latent trajectory models in pooled survey datasets by Aswathi Saji, Jeswin Baby, Jeswin Baby, Prem Antony, Srishti Sinha, Sulagna Bandyopadhyay, Joby K. Jose, Anura V. Kurpad, Tinku Thomas

“…We aimed to identify and characterize distinct growth trajectories of Indian children from birth to 12 months of age residing in urban and rural areas.MethodsPooled data from four interventional and non-interventional longitudinal studies across India were used for the analysis. Latent class mixed modeling (LCMM) was employed to identify groups of children with similar trajectories over age. …”
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Evidence linking phthalate exposure to alterations of hematologic parameters in Chinese children: A cross-sectional study by Mei-Ting Wei, Ying Wen, Zhu-Xia Zhang, Xiu-Ju Liu, Feng-Xiang Wei, Wei-Qiang Liu, Li Zhou, Ding-Yan Chen, Yao Yao

“…It is worth noting that among the mixed effects, MEOHP and MEHP had the greatest impact on the four hematologic parameters and showed a consistent negative correlation. …”
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Emergency Airway Management: A Systematic Review on the Effectiveness of Cognitive Aids in Improving Outcomes and Provider Performance by Raisa Chowdhury, Ostap Orishchak, Marco A. Mascarella, Bshair Aldriweesh, Mohammed K. Alnoury, Guillaume Bousquet-Dion, Jeffrey Yeung, Lily Ha-Nam P. Nguyen

“…<b>Results:</b> Five studies met inclusion criteria, encompassing randomized controlled trials, controlled studies, and mixed-methods research. Cognitive aids improved decision-making times (reduced by 44.6 s), increased procedural success rates, and enhanced non-technical skills such as teamwork and crisis management. …”
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Traces of Paleolithic expansion in the Nivkh gene pool based on data on autosomal SNP and Y chromosome polymorphism by V. N. Kharkov, N. A. Kolesnikov, L. V. Valikhova, A. A. Zarubin, A. L. Sukhomyasova, I. Yu. Khitrinskaya, V. A. Stepanov

“…The Nivkh gene pool confirms the relative smallness of their ancestral groups without mixing with other populations.…”
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Identification of climate-sensitive disease incidences in vietnam: A longitudinal retrospective analysis of infectious disease rates between 2014 and 2022 by Cuong Quoc Hoang, Quang Phuong Huynh Nguyen, Thao Phuong Huynh Nguyen, Hieu Trung Nguyen, Linh Thuy Hoang, Giang Huong Vu, Woong-Ki Kim, Hai Duc Nguyen

“…Objective: There is a growing correlation between the rise in infectious diseases and climate change; however, little is known about the interactions and mixed effects of climate factors on infectious diseases. …”
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Preparation, Purification, Identification and Anti-lipid Oxidation of Kidney Bean Skin Polyphenols by Lilan SUN, Kun WANG, Youliang ZHANG, Ruokun WANG, Feng ZUO

“…Using a model, it was calculated that peanut oil mixed with polyphenols-vitamin C had a maximum shelf life of 193.4 d at 20 ℃, control group was 150.3 d, with a maximum relative error of 8.7% compared to measured values, accurately predicting the shelf life of the edible oil. …”
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Lidar estimates of birch pollen number, mass, and CCN-related concentrations by M. Filioglou, P. Tiitta, P. Tiitta, X. Shang, A. Leskinen, P. Ahola, S. Pätsi, A. Saarto, V. Vakkari, V. Vakkari, U. Isopahkala, M. Komppula

“…The results show that under well-mixed conditions, surface measurements from in situ instrumentation can be correlated with lidar observations at higher altitudes to estimate the conversion factors. …”
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Size-resolved Compositional Analysis and Source Apportionment of Submicron Aerosol during Lockdown Period Using HR-ToF-AMS by Prodip Acharja, Akash Vispute, Prasanna Lonkar, Suresh W. Gosavi, Sreyashi Debnath, Narendra G. Dhangar, Kaushar Ali, Gaurav Govardhan, Sachin D. Ghude

“…The size-resolved analysis showed the unimodal size distribution of organic and inorganic constituents with peaks at 550 nm, implying the dominant presence of mixed and aged aerosol species. The stoichiometric neutralization analysis showed the almost neutralized nature of submicron aerosol with an average aerosol neutralization ratio (ANR) of 0.8. …”
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Concentration-dependent effects of immunomodulatory cocktails on the generation of leukemia-derived dendritic cells, DCleu mediated T-cell activation and on-target/off-tumor toxici... by Hazal Aslan Rejeski, Hazal Aslan Rejeski, Anne Hartz, Anne Hartz, Elias Rackl, Elias Rackl, Lin Li, Lin Li, Christoph Schwepcke, Christoph Schwepcke, Kai Rejeski, Kai Rejeski, Christoph Schmid, Christoph Schmid, Andreas Rank, Andreas Rank, Jörg Schmohl, Doris Kraemer, Peter Bojko, Helga Maria Schmetzer, Helga Maria Schmetzer

“…For Kit-M, we noted optimal generation of DC-subsets at intermediary concentration ranges of PGE1 (0.25-4.0 µg/mL), which facilitated upregulation of activated and memory T-cells upon mixed lymphocyte culture, and efficient anti-leukemic activity in cytotoxicity assays. …”
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Direct high-precision radon quantification for interpreting high-frequency greenhouse gas measurements by D. Kikaj, E. Chung, A. D. Griffiths, S. D. Chambers, G. Forster, G. Forster, A. Wenger, P. Pickers, P. Pickers, C. Rennick, S. O'Doherty, J. Pitt, K. Stanley, D. Young, L. S. Fleming, L. S. Fleming, K. Adcock, E. Safi, T. Arnold, T. Arnold

“…Radon, emitted naturally from the land surface, can be used as a tracer of atmospheric transport and mixing to independently evaluate the performance of such models. …”
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Transforming the Health Research Workforce in Mozambique: Achievements of the Mozambique Institute for Health Education and Research (MIHER) over a 13-Year Journey by Emília Virgínia Noormahomed, Sérgio Noormahomed, Matchecane Cossa, Nicole Joyce, Regina Daniel Miambo, Irina Mendes Sousa, Noémia Nhacupe, Tufária Mussá, Jahit Sacarlal, Lídia Gouveia, Luís Jorge Ferrão, Carla Carrilho, Mamudo Ismail, Davey Smith, Natasha K. Martin, Ravi Goyal, Kim E. Barrett, Sónia Santana Afonso, Amélia Mandane, Alarquia Saíde, Pompílio Vintuar, Brígida Singo, Boaventura Aleixo, Luck Injage, Elizabeth A. Winzeler, Paulo Correia-de-Sá, Maria do Rosário Oliveira Martins, Paulo Ferrinho, Sam Patel, Ana Olga Mocumbi, Stephen W. Bickler, Constance A. Benson, Roberto Badaró, Robert T. Schooley

“…Objective: The manuscript provides an overview and discusses lessons learned about the pioneering role of the Mozambique Institute for Health Education and Research (MIHER) as the first research support center (RSC) in supporting the management of research grants in Mozambique, emphasizing its impact on research capacity development. Methods: Using mixed methods, data were comprehensively collected to identify MIHER’s primary achievements from 2010 to 2023. …”
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