Study protocol: an observational study of distress, immune function and persistent pain in HIV by John A Joska, Mark R Hutchinson, Maia Lesosky, Victoria J Madden, Ncumisa Msolo, Luyanduthando Mqadi, Gillian J Bedwell, Jonathan Grant Peter, Romy Parker, Andrew Schrepf, Robert R Edwards

“…To test the hypothesis that IR is positively associated with SH, data from the subsample will be analysed with generalised mixed effects models to estimate the association between IR and group membership, with SH as the dependent variable.Ethics and dissemination Information obtained from this study will be published in peer-reviewed journals and presented at scientific meetings. …”
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Enhanced AC/DC optimal power flow via nested distributed optimization for AC/VSC-MTDC hybrid power systems by Haixiao Li, Pedro P. Vergara, Robert Dimitrovski, Hongjin Du, Aleksandra Lekić

“…To address this issue, an enhanced AC/DC optimal power flow (OPF) is specifically proposed. Firstly, a mixed-integer convex AC/DC OPF model is explicitly formulated to describe the optimal operation of such hybrid power systems. …”
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Epidemiological and Clinical Characteristics of Pediatric Acute Drug Intoxications: A Retrospective Analysis by Cristina Elena Singer, Renata-Maria Văruț, Maria Singer, Simona Cosoveanu, Jaqueline Abdul Razzak, Madalina Elena Popescu, Simina Gaman, Ileana Octavia Petrescu, Cristina Popescu

“…The inclusion criteria encompassed children aged 0–17 years with confirmed pharmaceutical intoxications. Cases involving mixed poisonings or non-pharmaceutical substances were excluded. …”
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The synchronous improvement of thermal stability, mechanical properties, thermal conductivity of oxide dispersion strengthened Cu–Cr alloy by microalloying Si by Yaju Zhou, Shengming Yin, Qian Lei, Jianglei Fan, Shizhong Wei, Youwei Yan

“…All three alloys exhibit heterogeneous mixed grain structures, including coarse and fine grains, with oxide nanoparticles uniformly distributed throughout the copper matrix. …”
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Enhancing resilience: the impact of a near-peer mentoring program on medical students by Lea Pölczman, Lea Pölczman, Dorottya Árva, Dorottya Árva, Zsuzsa Győrffy, Márk Jámbor, András Végh, András Végh, Gergő Kristóf, György Purebl, Edmond Girasek

“…Statistical analysis involved descriptive statistics and mixed linear models for repeated-measures ANOVA.ResultsResults showed a significant increase in resilience for the case group compared to the control group (F (1, 129) = 5.578, p = 0.020), with no significant main effect of time. …”
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Pain management in trauma: the need for trauma-informed opioid prescribing guidelines by Ben L Zarzaur, Suresh Agarwal, Colleen Trevino, Amelia Baltes, David M Horton, Julia Malicki, Randall T Brown

“…Changes in opioid prescribing guidelines during the past several years have yielded mixed results for pain management after trauma, with a limiting factor being the heterogeneity of clinical populations and treatment needs in individuals receiving opioids. …”
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Predictors of missed hospital appointments in patients with posterior compartment pelvic floor disorders in a tertiary referral centre by Tanzeela Gala, Mehak Saini, Abigail Fernandes, Carlotta Sarzo, Noman Shahzad, Carlene Igbedioh, Alexis Schizas, Linda Ferrari, Alison Hainsworth

“…Missed appointments recorded were: TTAC — 45 (2.2%), BFC — 309 (15.8%), EAUS — 476(24%), PFUS — 484(37.2%) and DP — 432(26.2%).Predictors determined were: Male gender, age <50 years, complaints of rectal pain and bleeding for missing telephone and face-to-face appointments, low socioeconomic status for missing face-to-face appointments, and mixed and other ethnic groups with missing telephone appointments. …”
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Structures and determinants of soil microbiomes along a steep elevation gradient in Southwest China by Ting Li, Ting Li, Ting Li, Ziyan Gao, Ping Zhou, Ping Zhou, Mingmin Huang, Gangzheng Wang, Jianping Xu, Wangqiu Deng, Mu Wang, Mu Wang

“…The Simpson indices of both soil bacteria and fungi demonstrated a hollow trend along the elevational gradient, with an abrupt decrease in bacterial and fungal diversity at 2,600 m a.s.l. in coniferous and broad-leaved mixed forests (CBM). Soil bacterial chemoheterotrophy was the dominant lifestyle and was predicted to decrease with increasing elevation. …”
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Digital tool as speech and language therapy for patients with post-stroke aphasia by Gerardo Ruiz Ares, Marta Martin Alonso, Ricardo Rigual, Carlos Hervás Testal, Gabriel Torres Iglesias, Laura Casado Fernandez, Elena de Celis Ruiz, Jorge Rodríguez Pardo, Jenny Carvajal Muñoz, Laura González Martín, María Alonso de Leciñana, Blanca Fuentes

“…Aphasia description: Broca's 12 (15.0%), Wernicke's 13 (32.5%), mixed/global 15 (37.5%) cases. Patients began using VerbalizAPP ® 4.8 days (range 2–7) after stroke onset. …”
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Cohort profile: maternal and child health and parenting practices during the COVID-19 pandemic in Ceará, Brazil: birth cohort study (Iracema-COVID) by Marcia C Castro, Márcia Maria Tavares Machado, Simone Farías-Antúnez, David Augusto Batista Sá Araújo, Ana Luiza Penna, Francisco Ariclene Oliveira, Camila Machado de Aquino, Antônio Silva Lima Neto, Geziel dos Santos de Sousa

“…Data were collected through standardised questionnaires that, in addition to sociodemographic and economic data, collected information on breast feeding, mental health status and COVID-19.Findings to date Results from the first wave show that the majority of participants have 9–11 years of schooling (54.4%; 95% CI 61.0 to 70.9) and are of mixed race (71.5%; 95% CI 66.5 to 76.0). At the time of the survey, 27.9% of the participants were out of the labor force (95% CI 23.5 to 32.9) and 78.6% reported a decrease in family income after restrictions imposed due to the pandemic (95% CI 74.0 to 82.6). …”
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Decision-making regarding place of end-of-life care for children with life-limiting and life-threatening conditions: a systematic integrative review by Ashleen Crowe, Fiona Hurley, Gemma Kiernan, Helen Kerr, Yvonne Corcoran, Jayne Price, Joanne Reid, Eileen Courtney, Tracey McConnell, Patricia McNeilly, Veronica Lambert

“…Quality appraisal was conducted using the Mixed Methods Appraisal Tool. Results Eleven eligible studies were included. …”
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Quantifying the Impact of Climate Change and Forest Management on Swedish Forest Ecosystems Using the Dynamic Vegetation Model LPJ‐GUESS by John Bergkvist, Fredrik Lagergren, Md. Rafikul Islam, David Wårlind, Paul A. Miller, Maj‐Lena Finnander Linderson, Mats Lindeskog, Anna Maria Jönsson

“…We compared three alternative forest policy scenarios: Business As Usual, with no change in the proportion of forest types within landscapes; Adaptation and Resistance, with an increased area of mixed stands; and EU‐Policy, with a focus on conservation and reduced management intensity. …”
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Risk perceptions and changes in tobacco use in relation to Coronavirus Disease 2019 pandemic: A qualitative study on adolescent tobacco users in Hong Kong by Tianqi Chen, Lijun Wang, Yee Tak Derek Cheung, Man Ping Wang, Tai Hing Lam, Sai Yin Ho

“…Family/peer influence had mixed impacts. Conclusions Adolescent tobacco users perceived lower COVID risks associated with HTPs and ECs than cigarettes, and various changes in tobacco use were found amid the pandemic in Hong Kong. …”
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Conservation networks do not match the ecological requirements of amphibians by Matutini, Florence, Baudry, Jacques, Fortin, Marie-Josee, Pain, Guillaume, Pithon, Josephine

“…Synthesis and applications - We advocate the need to better integrate agricultural landscape mosaics into species conservation planning as well as to protect and promote agroecological practices suitable for biodiversity, including mixed and extensive livestock farming. We also emphasize the importance of interacting landscape elements of green infrastructure for amphibian conservation and the need for these to be effectively considered in land-use planning policies. …”
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Self-reported sexually transmitted infections and associated factors among sexually active men in East Africa: a multilevel analysis of recent demographic and health surveys by Beminate Lemma Seifu, Yohannes Mekuria Negussie, Bezawit Melak Fente, Zufan Alamrie Asmare, Angwach Abrham Asnake, Meklit Melaku Bezie, Hiwot Atlaye Asebe

“…This silent impact can lead to substantial morbidity and mortality, which is particularly pronounced in East Africa.Objective To investigate the prevalence and factors associated with self-reported STIs among sexually active men in East Africa.Design Cross-sectional study design.Setting 10 East African countries.Participants 66 833 sexually active men.Primary outcome measure Self-reported STI in the 12 months preceding the survey. A multilevel mixed-effects logistic regression model was fitted to identify factors associated with self-reported STIs. …”
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Prevalence of Dental Anomalies in Pediatric Patients at King Saud University Dental Hospital, Riyadh, Saudi Arabia—A Radiographic Analysis by Mannaa K. Aldowsari, Ayman M. Sulimany, Abdulmajeed Alkhathlan, Nawaf Alfhaed, Mohammed Aldosari, Saud Alayed, Saad Bin Saleh, Abeer A. Alshami

“…Most study participants had mixed dentition and were healthy. The prevalence of dental anomalies reported in this study was as follows: 4.6% hypodontia, 2.7% ectopic eruption, 1.63% taurodontism, 1.2% infra-occluded molars, 1.1% impacted teeth, 0.75% root dilaceration, and 0.65% supernumerary teeth. …”
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Green synthesis of Au-Pt bimetallic nanoparticels using Croton caudatus Geisel leaf extract and their biological studies by P.Vijaya Kumar, K.S. Pushpavalli, Baskaran Ganesh Kumar, S.Mary Jelastin Kala, K.S. Prakash

“…Bimetallic nanoparticle synthesis generally involves mixing two different aqueous metal solutions with a natural reducing agent, like a plant extract. …”
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Age-stratified trends and outcomes of inpatient cholecystectomy for acute cholecystitis in the United States by Ayesha P. Ng, Joseph E. Hadaya, Sara Sakowitz, Zihan Gao, James Wu, Peyman Benharash

“…Major adverse events included in-hospital mortality and complications. Multivariable mixed regression was used to evaluate the association of age group with outcomes. …”
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Human-centered design of a health recommender system for orthopaedic shoulder treatment by Akanksha Singh, Benjamin Schooley, John Mobley, Patrick Mobley, Sydney Lindros, John M. Brooks, Sarah B. Floyd

“…Ten orthopaedic surgeons participated in a mixed methods evaluation of the I-C-IT prototype that was produced. …”
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Single Nucleotide Polymorphisms, Associated with Increased Risk of Irritable Bowel Syndrome with Predominant Constipation: A Meta Analysis by E. A. Trush, A. E. Karchevskaya, R. V. Maslennikov, E. A. Poluektova, O. S. Shifrin, V. T. Ivashkin

“…Our meta-analysis revealed that ADRA2A 1291C&gt;G polymorphism was significantly associated with both IBS and IBS-C in the mixed population. Neither homozygous nor heterozygous variants of the SLC6A4 (5-HTTLPR) polymorphism and GNB3 C825T polymorphism were associated with either IBS-C or IBS as a whole.…”
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