Barriers and facilitators of loaded self-managed exercises and physical activity in people with patellofemoral pain: understanding the feasibility of delivering a multicentred rand... by Michael Skovdal Rathleff, Phillipa Logan, Marcus Bateman, Benjamin E Smith, Fiona Moffatt, Paul Hendrick, James Selfe, Toby O Smith

“…The trial investigated a loaded self-managed exercise intervention, which included education and advice on physical activity versus usual physiotherapy as the control.Design Qualitative study, embedded within a mixed-methods design, using semi-structured interviews.Setting A UK National Health Service physiotherapy clinic in a large teaching hospital.Participants Purposively sampled 20 participants within a feasibility RCT study; 10 patients with a diagnosis of patellofemoral pain, aged between 18 and 40 years, and 10 physiotherapists delivering the interventions.Results In respect to barriers and facilitators, the five overlapping themes that emerged from the data were: (1) locus of control; (2) belief and attitude to pain; (3) treatment expectations and preference; (4) participants’ engagement with the loaded self-managed exercises and (5) physiotherapists’ clinical development. …”
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Effects of Calliandra and Sesbania on Daily Milk Production in Dairy Cows on Commercial Smallholder Farms in Kenya by D. N. Makau, J. A. VanLeeuwen, G. K. Gitau, S. L. McKenna, C. Walton, J. Muraya, J. J. Wichtel

“…Descriptive and univariable statistical analyses were conducted, and multivariable mixed-model regression was used for identification of factors associated (P<0.05) with daily milk production. …”
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Patients’ preferences for health insurance coverage of new technologies for treating chronic diseases in China: a discrete choice experiment by Jinsong Geng, Xiaowei Chen, Haini Bao, Danmin Qian, Yuting Shao, Hao Yu

“…After conducting the DCE, we analysed the data by mixed logit regression to examine patient-reported preferences for each attribute.Setting The DCE was conducted with patients in six tertiary hospitals from four cities in Jiangsu province.Participants Patients aged 18 years or older with a history of diabetes or hypertension and taking medications regularly for more than 1 year were recruited (n=408).Results The technology attributes regarding expected gains in health outcomes from the treatment, high likelihood of effective treatment and low incidence of serious adverse events were significant, positive predictors of choice by the study patients (p&lt;0.01). …”
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Can muscle synergies shed light on the mechanisms underlying motor gains in response to robot-assisted gait training in children with cerebral palsy? by Gloria P. Vergara-Diaz, Stefano Sapienza, Jean-François Daneault, Eric Fabara, Catherine Adans-Dester, Giacomo Severini, Vincent C. K. Cheung, Carmen Echevarría Ruiz de Vargas, Donna Nimec, Paolo Bonato

“…Results Three and, less often, two muscle synergies were detected in study participants pre-RGT. Linear mixed effect models showed that composition of the muscle synergies and their temporal activation coefficients present deviations from normative data proportional to the severity of functional limitations (i.e., GMFCS levels, p < 0.01). …”
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BIMSSA: enhancing cancer prediction with salp swarm optimization and ensemble machine learning approaches by Pinakshi Panda, Sukant Kishoro Bisoy, Amrutanshu Panigrahi, Abhilash Pati, Bibhuprasad Sahu, Zheshan Guo, Haipeng Liu, Prince Jain

“…The ensemble ML-based model BIMSSA was evaluated using microarray data from four different cancer types: Adult acute lymphoblastic leukemia and Acute myelogenous leukemia (ALL-AML), Lymphoma, Mixed-lineage leukemia (MLL), and Small round blue cell tumors (SRBCT).ResultsIn terms of accuracy, the proposed BIMSSA (Boruta + IMRMR + SSA) achieved 96.7% for ALL-AML, 96.2% for Lymphoma, 95.1% for MLL, and 97.1% for the SRBCT cancer datasets, according to the empirical evaluations.ConclusionThe results show that the proposed approach can accurately predict different forms of cancer, which is useful for both physicians and researchers.…”
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Structured lactation support for mothers of very low birthweight preterm infants and establishment of human donor milk banks in German NICUs (Neo-MILK): protocol for a hybrid type... by Angela Kribs, Nicole Ernstmann, Nadine Scholten, Martin Hellmich, Antje Hammer, Eva Mildenberger, Andreas Müller, Dirk Horenkamp-Sonntag, Juliane Köberlein-Neu, Tim Ohnhäuser, Katja Matthias, Jens Ulrich Rüffer, Nicola Gabriela Dymek, Julia Jaschke, Anna Katharina Stirner, Isabella Schwab, Daniel Wiesen, Till Dresbach, Friederike Eyssel, Katharina Lugani, Anne Sunder-Plaßmann, Melanie Klein, Christoph Rupprecht

“…Statistical analysis will be performed using generalised linear mixed models.Ethics and dissemination Data collection, storage and analysis comply with current data protection regulations. …”
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Efficacy and safety of home-based transcranial direct current stimulation as adjunct treatment for cognitive improvement in major depressive disorder: A double-blind, randomized, m... by CW Lee, K Park, JE Ahn, Y Jang, YS Park, H Yu, D Lee, HK Ihm, J Lee, J Kim, YI Lee, S-E Lim, SS Kwon, HY Park, TH Ha, I-Y Yoon, Woojae Myung, Ji Hyun Baek

“…Mean changes in the total accuracy scores from baseline to week 6 were compared across the three groups using an F-test. Linear mixed-effects models examined the interaction of group and time. …”
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Balancing legume-cereal proportions in cover crop mixtures to minimize N2O emissions by Guillermo Guardia, Diego Abalos, Emanuele Ribatti, Federico Ardenti, Federico Capra, Giacomo Mortella, Vincenzo Tabaglio, Miguel Ángel Ibáñez, Ji Chen, Andrea Fiorini

“…During the first phase, the proportion of fine/very fine roots and root length density were negatively correlated with mineral N content and N2O emissions. Mixing rye with vetch increased total dry biomass and N yield for all mixtures compared to rye alone. …”
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Provocative tests of anal sphincter function correlate with symptoms and subtypes of faecal incontinence by John McLaughlin, Dipesh H Vasant, Asbjørn Mohr Drewes, Abhiram Sharma, Matthew Davenport, Edward Kiff, Karen Telford, Alexander O'Connor, Donghua Liao, Niels Klarskov

“…FI severity was assessed with the Vaizey score and quality-of-life with the Manchester Health Questionnaire.Results 40 patients (39 women, median age: 62 (range: 38–85)) were recruited with 27 (67.5%) reporting urge FI, 8 (20%) mixed and 5 (12.5%) passive incontinence. FLIP squeeze measurements correlated with the Vaizey score, including incremental squeeze pressure at 40 mL (rs=−0.412; p=0.008) and 50 mL (rs=−0.414; p=0.009) and the pressure-diameter volume loop at 50 mL (rs=−0.402; p=0.011). …”
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A woman’s place is in theatre: women’s perceptions and experiences of working in surgery from the Association of Surgeons of Great Britain and Ireland women in surgery working grou... by Maria Irene Bellini, Yitka Graham, Catherine Hayes, Roxanna Zakeri, Rowan Parks, Vassilios Papalois

“…No patients were involved in the study.Primary and secondary outcome measures Data were analysed through a mixed-methods approach. The quantitative data were analysed through descriptive statistics and qualitative analysis was undertaken using a constant comparative analysis of the participants’ comments, to identify salient patterns (themes).Results A total of 81 female participants replied (42% response rate based on the Facebook group members), with 88% (n=71) perceiving surgery as a male-dominated field. …”
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The Role of Microfabric and Laminae on Pore Structure and Gas Transport Pathways of Marine Shales from Sichuan Basin, China by Yi Shu, Shang Xu, Feng Yang, Zhiguo Shu, Pan Peng, Senxin Huang, He Zhen

“…Argillaceous/siliceous mixed shales are well laminated, whereas argillaceous shales contain many oriented clay flakes along the lamination. …”
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Study protocol for a stepped-wedge implementation study investigating the intersectoral collaboration of implementing the TREAT INTERACT intervention for primary school teachers an... by Ane-Marthe Solheim Skar, Ingunn Marie S. Engebretsen, Nora Braathu, Harriet Aber, Harald Bækkelund, Melf-Jakob Kühl, Marjorie Mukisa, Joyce Sserunjogi Nalugya, Norbert Skokauskas, Vilde Skylstad, Tore Wentzel-Larsen, TREAT research consortium, Juliet Ndimwibo Babirye

“…Methods This is a pragmatic mixed-methods hybrid Type II implementation-effectiveness study utilizing a co-design approach. …”
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Otologic Manifestations in Patients with Achondroplasia: A Multicenter Study by Dohee Kim, Joonsik Yoon, Myung-Whan Suh, Jun Ho Lee, Moo Kyun Park

“…Results: Among 53 patients who underwent audiometry, 26 showed conductive hearing loss, 2 had mixed-type hearing loss, and 4 had sensorineural hearing loss. …”
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Associations between exposure to volatile organic compounds with obesity in adults by Runmiao Wu, Lei Jia, Xu Zhu, Gongchang Guan, Junkui Wang, Rutai Hui, Meijuan Ma, Zhao Zhao, Hui Pang, Ling Zhu

“…Quantile g-computation (Qgcomp) regression, a method designed to evaluate the combined effects of multiple correlated chemical exposures, was used to assess the mixed influence of VOC metabolites on obesity-related outcomes. …”
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Impact of secondary ice production on thunderstorm electrification under different aerosol conditions by S. Huang, J. Yang, J. Yang, J. Li, Q. Chen, Q. Zhang, F. Guo

“…It is found that as the aerosol concentration increases, more but smaller cloud droplets can be lofted to mixed-phase regions. The warm-rain process is suppressed, and the declined raindrop concentration leads to fewer graupel particles. …”
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Effectiveness of the mobile Stress Autism Mate Junior application in reducing stress and improving quality of life in adolescents with autism: a pilot study by Alvin van Asselt, Kirsten Hoeberichts, Kirsten Hoeberichts, Sevda Demirel, Sevda Demirel, Anke Scheeren, Anke Scheeren, Yvette Roke

“…Data were collected at four time points separated by four weeks: Control, pre-test, post-test and follow-up. Linear mixed-effects models were used to analyze the data.ResultsAt post-test, use of the SAM Junior app had no significant effects on participants’ perceived stress (B = 0.31; 95% CI [-1.59, 2.22], p = .73), adaptive coping (B = -1.38; 95% CI [-5.69, 2.94], p = .51), maladaptive coping (B = -0.63; 95% CI [-4.56, 3.30], p = .74) and quality of life (B = -4.13; 95% CI [-12.19, 3.94], p = .29). …”
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Research note: Establishment of a multiplex PCR detection system for different infectious bronchitis virus strain genotypes in laying hens by Changjing Zhao, Cheng Yuan, Qingsen Zhao, Aihong Xia, Yaqing Dong, Shuying Xu, Shihan Chen, Yue Yuan, Yongjuan Wang

“…It was subsequently applied to the identification of purposefully randomly mixed infections of two, three, four or five IBV strains mentioned above in samples of chicken embryos. …”
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Composite Flours Based on Black Lentil Seeds and Sprouts with Nutritional, Phytochemical and Rheological Impact on Bakery/Pastry Products by Christine (Neagu) Dragomir, Sylvestre Dossa, Călin Jianu, Ileana Cocan, Isidora Radulov, Adina Berbecea, Florina Radu, Ersilia Alexa

“…This paper aimed to study the nutritional, phytochemical and rheological properties of some composite flours based on wheat flour (WF) mixed with non-germinated (LF) and sprouted lentil flour (SLF), in order to fortify the wheat flour and to obtain functional bakery/pastry products. …”
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Efficacy of the Foodbot Factory digital curriculum-based nutrition education intervention in improving children’s nutrition knowledge, attitudes and behaviours in elementary school... by Wendy Lou, Michael Farkouh, JoAnne Arcand, Jacqueline Marie Brown, Saman Tahir, Beatriz Franco-Arellano, Ann LeSage, Janette Hughes, Bill Kapralos, Ellen Vogel, Claire Tugault-Lafleur

“…Outcomes will be assessed at baseline, immediately postintervention, and 4 weeks and 3 months postintervention using the Nutrition Attitudes and Knowledge questionnaire, the Block Kids Food Screener, a modified Family Nutrition and Physical Activity screener and an acceptability questionnaire. Generalised linear mixed models will assess changes in outcomes between groups.Ethics and dissemination The study protocol is approved by research ethics boards at Ontario Tech University and participating school boards. …”
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Estimating residential building material demand for Ahmedabad 2050 and its impact on CO2 emissions by Chaitali Trivedi, Minal Pathak, Bhargav Adhvaryu

“…The objective of the study was to estimate future housing stock for Ahmedabad and its impact on material demand and CO2 emissions this study adopted a mixed-method approach. The estimated material demand (EMD) for 2050 was derived from the calculated total constructed floor area (CFA) and quantity of material consumption per square meter. …”
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