Esketamine at a Clinical Dose Attenuates Cerebral Ischemia/Reperfusion Injury by Inhibiting AKT Signaling Pathway to Facilitate Microglia M2 Polarization and Autophagy by Gao Y, Li L, Zhao F, Cheng Y, Jin M, Xue FS

“…Ying Gao,1 Lu Li,1 Fang Zhao,1 Yi Cheng,1 Mu Jin,2 Fu-Shan Xue1,3 1Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, People’s Republic of China; 3Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Fuzhou, People’s Republic of ChinaCorrespondence: Mu Jin, Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, No. 2 An-Zhen Road, Chao-Yang District, Beijing, 100029, People’s Republic of China, Tel +86-13366600987, Email jinmu0119@hotmail.com Fu-Shan Xue, Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong-An Road, Xi-Cheng District, Beijing, 100050, People’s Republic of China, Tel +86-13911177655, Fax +86-591-88217841, Email xuefushan@aliyun.com; xuefushan@mail.ccmu.edu.cnPurpose: This study aimed to assess the protective effect of a clinical dose esketamine on cerebral ischemia/reperfusion (I/R) injury and to reveal the potential mechanisms associated with microglial polarization and autophagy.Methods: Experimental cerebral ischemia was induced by middle cerebral artery occlusion (MCAO) in adult rats and simulated by oxygen-glucose deprivation (OGD) in BV-2 microglial cells. …”
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Comparison of Clinical Characteristics and Mortality Outcome in Critical COVID-19 Patients Infected with Alpha and Omicron Variants by Cheng HI, Chang KW, Wu BC, Teo MY, Hung WS, Wu HM, Huang ACC, Lin CW, Lin TY, Lin HC, Chiu CH, Lin SM

“…Hsin-I Cheng,1 Ko-Wei Chang,1 Bing-Chen Wu,1 Mei-Yuan Teo,1 Wei-Syun Hung,1 Hao-Ming Wu,1 Allen Chung-Cheng Huang,1 Chang-Wei Lin,2 Ting-Yu Lin,1 Horng-Chyuan Lin,1 Cheng-Hsun Chiu,3,4 Shu-Min Lin1,5– 7 1Department of Thoracic Medicine, Chang Gung Memorial Hospital, Linkuo, Taiwan; 2Department of Thoracic Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan; 3Department of Pediatrics, Chang Gung Children’s Hospital, Chang Gung University College of Medicine, Taoyuan City, Taiwan; 4Molecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan; 5Department of Respiratory Therapy, Chang Gung Memorial Hospital, Linkuo, Taiwan; 6School of Medicine, National Tsing Hua University, Hsin-Chu, Taiwan; 7School of Medicine, Chang Gung University, Taoyuan, TaiwanCorrespondence: Shu-Min Lin, Department of Thoracic Medicine, Chang Gung Memorial Hospital, 199 Tun-Hwa N. …”
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Optimizing Obstructive Sleep Apnea Risk Assessment in Hypertension: Development of a Predictive Nomogram in China by Yang Y, Sun X, Liang J, Liao WF, Ye W, Zheng Z, Du L, Chen M, Zhang Y, Lin W, Huang J, Yao W, Chen R

“…Yitian Yang,1,* Xishi Sun,2,* Jinhua Liang,1,* Wei Feng Liao,1,* Weilong Ye,1 Zhenzhen Zheng,1 Lianfang Du,1 Mingdi Chen,1 Yuan Zhang,3 Wenjia Lin,2 Jinyu Huang,2 Weimin Yao,1 Riken Chen1,4 1The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524003, People’s Republic of China; 2Emergency Medicine Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524001, People’s Republic of China; 3The First Clinical School of Medicine, Guangdong Medical University, Zhanjiang, Guangdong, 524003, People’s Republic of China; 4State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510120, People’s Republic of China*These authors contributed equally to this workCorrespondence: Riken Chen; Weimin Yao, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524003, People’s Republic of China, Tel +13560244631 ; +13822521722, Email chenriken@126.com; 490296443@qq.comPurpose: Obstructive sleep apnea (OSA) is common in patients with hypertension. …”
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ORGANISING A «SERATA ITALIANA»: A PROJECT-BASED LEARNING EXPERIENCE WITH FLEMISH STUDENTS OF L2 ITALIAN by Elisa De Cristofaro, Irene Cenni, Emma Grootvelt

“…Con queste considerazioni, l’articolo contribuisce alla letteratura accademica sull’uso del PBL nell’acquisizione di lingue straniere. …”
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Oryantalist Tarih Yazımının Seyyid Ahmed Han ve Aligarh Hareketi Üzerindeki Etkileri -Bâbürlülerin Gerilemesi Özelinde- by Salih Kalkan

“…Bu etkinin bir tezahürü mahiyetinde hem Hindu ulusalcılar, hem de Hintli Müslümanlar farklı perspektiften konuya yaklaşmakta olsalar dahi genel itibarıyla süreci İngiliz oryantalistlerin yaklaşımlarına uygun olacak şekilde Bâbürlüler üzerinden tek taraflı olarak yürütmektedirler. …”
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Skaitmeninių metodų taikymas praeities kelionių tyrimuose by Rimvydas Laužikas

“…Atsižvelgiant į šaltinių specifiką (šaltiniuose ir jų vertimuose vartojamas kalbas) buvo sukurtas daugiakalbis lietuvių–lenkų–anglų–rusų–vokiečių kalbų žodynas. Žodyno struktūrą sudaro šeši su praeities kelionėmis susiję konceptai (kategorijos): (i) kelionė (bendras apibūdinimas), (ii) kelias ir jo infrastruktūra (tiltai, brastos ir kt.), (iii) transporto priemonės, (iv) sustojimo ir nakvynės vietos (miesteliai, kaimai, karčemos, pašto stotys ir kt.), (v) kelyje sutikti žmonės (smuklininkai, plėšikai, vedliai ir kt.), (vi) kelionių maistas. …”
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„Węgry to miejsce, w którym trzeba teraz być”. Węgierski postliberalizm i jego wpływ na amerykańskich konserwatystów by Nicholas Morieson

“…Zainteresowanie amerykańskich postliberałów Orbánem doprowadziło kilku z nich do złożenia mu wizyty, a także do podjęcia decyzji o zorganizowaniu konferencji Conservative Political Action Conference w 2022 r. w Budapeszcie. …”
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Pengaruh Aplikasi Bahan Pemutih Gigi Karbamid Peroksida 10% dan Hidrogen Peroksida 6% secara Home Bleaching terhadap Kekerasan Permukaan Email Gigi by Meiyestri Dwi Riani, Fadil Oenzil, Nila Kasuma

“…Selama aplikasi kedua sampel berada dalam inkubator 370C. Kekerasan permukaan email gigi diukur dengan alat Vickers Harndness Tester. …”
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Viral Mimetic Bacterial Outer Membrane Vesicles for Targeting Angiotensin-Converting Enzyme 2 by Ahn G, Yoon HW, Jeong JH, Kim YH, Shin WR, Song MS, Ahn JY

“…The confirmation of the RBD expressed on OMVs was performed using trypsin treatment.Results: Our viral mimetic Ag43β 700_RBD OMVs had an impact on the theranostic studies: (i) angiotensin-converting enzyme 2 blockade assay, (ii) enzyme-linked immunosorbent assay for the OMVs, and (iii) intracellular uptake and neutralization assay. …”
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A Multifunctional MIL-101-NH2(Fe) Nanoplatform for Synergistic Melanoma Therapy by Shang J, Chen Y, Wang F, Yang J, Li Y, Yang L, Liu X, Zhong Z, Yue C, Zhou M

“…Jinlu Shang,1,2,* Yongjun Chen,2,* Fangliang Wang,3,* Jing Yang,2 Yi Li,4 Liuxuan Yang,2 Xiuqiong Liu,1 Zhirong Zhong,5 Chaochi Yue,6 Meiling Zhou2 1Department of Pharmacy, West China Hospital Sichuan University Jintang Hospital, Chengdu, Sichuan, 610400, People’s Republic of China; 2Department of Pharmacy, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People’s Republic of China; 3Chongqing Key Laboratory for Pharmaceutical Metabolism Research, Chongqing Pharmacodynamic Evaluation Engineering Technology Research Center, College of Pharmacy Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 4Department of Nuclear Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People’s Republic of China; 5Department of Pharmaceutical Sciences, School of Pharmacy, Southwest Medical University, Luzhou, Sichuan, 646000, People’s Republic of China; 6Department of Traditional Chinese Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Meiling Zhou; Chaochi Yue, Email meilzhou@163.com; yuechaochi18@swmu.edu.cnBackground: Melanoma is an aggressive form of skin cancer, and single-modality treatments often fail to prevent tumor recurrence and metastasis. …”
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COMUNICARE ALL’UNIVERSITÀ: QUANDO L’INTERAZIONE ORALE SI FA PLURILINGUE by Cristiana Cervini, Emanuela Paone

“…Nel nostro contributo intendiamo esplorare le caratteristiche della comunicazione accademica in contesti di insegnamento/apprendimento dell’intercomprensione tra lingue romanze, partendo da un corpus di interazioni orali in italiano, portoghese e spagnolo, videoregistrate in occasione di percorsi di formazione rivolti a studenti di Ingegneria gestionale e di Scienze mediche veterinarie dell’Università di Bologna, dell’Universidad Nacional de Rosario e dell’Universidade de São Paulo. …”
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Development and Validation of a Prognostic Molecular Phenotype and Clinical Characterization in Grade III Diffuse Gliomas Treatment with Radio-Chemotherapy by Gu W, Tang J, Liu P, Gan J, Lai J, Xu J, Deng J, Liu C, Wang Y, Zhang G, Yu F, Shi C, Fang K, Qiu F

“…Weiguo Gu,1,2,* Jiaming Tang,2,* Penghui Liu,1 Jinyu Gan,1 Jianfei Lai,1 Jinbiao Xu,2 Jianxiong Deng,2 Chaoxing Liu,1 Yuhua Wang,2 Guohua Zhang,3 Feng Yu,1,2 Chao Shi,2,3 Ke Fang,2 Feng Qiu2,3 1Department of Oncology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, People’s Republic of China; 2Department of Oncology, Gaoxin Branch of the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, People’s Republic of China; 3Nanchang Key Laboratory of Tumor Gene Diagnosis and Innovative Treatment Research, Gaoxin Branch of the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Jiangxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Feng Qiu, Department of Oncology, Gaoxin Branch of the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People’s Republic of China, Email ndyfy01149@ncu.edu.cn Ke Fang, Department of Oncology, Gaoxin Branch of the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Jiangxi, People’s Republic of China, Email fangkeqq88@163.comBackground: The relationship between molecular phenotype and prognosis in high-grade gliomas (WHO III and IV, HGG) treated with radiotherapy and chemotherapy is not fully understood and needs further exploration.Methods: The HGG patients following surgery and treatment with radiotherapy and chemotherapy. …”
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DON ANTE ADŽIJA – ZABORAVLJENI STARIGRADSKOPAKLENIČKI VELIKAN by MIRJANA TROŠELJ

“…Kao suradnik Muzeja hrvatskih spomenika i član Starinarskog muzejskog društva u Kninu, sudjelovao je 1941. u spašavanju starohrvatske baštine s područja sjeverne Dalmacije. …”
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Din Görevlilerinin İtikâdî Mezheplerin Temel Görüşleri İle İlgili Bilgi Düzeylerinin Farklı Değişkenler Bakımından Değerlendirilmesi by Muhammed Emin Altın, Mehmet Kubat

“…Veriler pandemi şartlarında oluşan mücbir şartlardan dolayı Google form üzerinden katılımcılara anket linki gönderilmek suretiyle toplanmıştır. Anketin uygulanması için ilgili kuruldan etik raporu alınmıştır. …”
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Muzyka i wolnomularstwo warszawskie na początku XIX wieku. Kilka nowych informacji dotyczących wolnomularskiej działalności Józefa Elsnera (ze zbiorów archiwum masońskiego w AGAD) by Małgorzata Sieradz

“…Szereg dodatkowych informacji dotyczących związków kompozytora i innych członków muzycznego środowiska warszawskiego przełomu XVIII i XIX w. i pierwszych dekad XIX stulecia z masonerią, a także zaangażowania Elsnera w bieżące życie polityczne ten sam autor zawarł w kilku innych opracowaniach, które ukazały się na przestrzeni dwudziestolecia międzywojennego; o masońskich epizodach w życiu kompozytora znajdujemy w poświęconej mu monografii wydanej w latach pięćdziesiątych XX w. przez polską muzykolog Alinę Nowak-Romanowicz, a rozproszone informacje na temat miejsca muzyki w obrzędach wolnomularskich odnaleźć można w podstawowej dla badań nad dziejami polskich masonów przełomu XVIII i XIX w. pracy Stanisława Załęskiego O masonii w Polsce od roku 1738 do 1822 na źródłach wyłącznie masońskich. …”
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Kilka uwag o pijarskich muzykach z XVII i XVIII wieku: Stachowicz, Pasternacki, Szczawnicki, Caspar by Ryszard Mączyński

“…Zasadniczy zrąb wiedzy na ten temat od półwiecza opierał się na klasycznym już dziś artykule Kultura muzyczna u pijarów w XVII i XVIII wieku, autorstwa dwojga muzykologów Anny i Zygmunta Szweykowskich oraz pijara Jana Innocentego Buby. …”
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