Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOk... by Narayanaswamy Venketasubramanian, Deidre Anne De Silva, Christopher P L H Chen, Cyrus G Escabillas, John Harold Hiyadan, Johnny K Lokin, Romulo U Esagunde, Joel M Advincula, Christian Oliver C Co, Maria Epifania V Collantes, Annabelle Y Lao, Yeow-Hoay Koh, Carol Huilian Tham

“…An independent Data Monitoring Committee oversees patient safety.Outcomes The primary outcome is mean change from baseline in FMA total score at 24 weeks. …”
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Microwave Ablation of T1a and T1b Renal Masses: A Retrospective Study by Assim Saad Eddin, Karan Rao, Bradford Oliva, Ajmain Chowdhury, Shetty Zubin, Chad Tracy, Brian J. Smith, Sandeep T. Laroia

“…There was no clinically significant change in renal function from pre- to postablation on day 1 or at 3 months. …”
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A SH3b domain-containing peptidoglycan recognition protein from Magallana gigas with broad recognition spectrum by Yinan Li, Hongbo Lu, Chuanyan Yang, Zhuyun Liu, Weilin Wang, Chang Liu, Lingling Wang

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Real-world study of phakic refractive lens for correction of high myopia by An-Peng Pan, Xu Shao, Yi-Ke Li, Zi-Yue Li, Qiong Yan, Wei-Yang Sun, A-Yong Yu

“…Mean endothelial cell loss was 11.3%, 9.6%, respectively, at 3 and 12 months, with no significant difference between the two follow-ups (P = 0.395). Fifty-nine eyes received the OVD-free method, and 49 eyes received the conventional method. …”
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Breeding and genetic aspects of creating productive forms of fast-developing spring bread wheat by B. V. Rigin, E. V. Zuev, V. A. Tyunin, E. R. Shreyder, Z. S. Pyzhenkova, I. I. Matvienko

“…These accessions had weak photoperiodic sensitivity and were insensitive to vernalization. The lines did not change their characteristics in different ecological conditions. …”
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A randomized, placebo-controlled, cross-over trial of ketamine in Rett syndrome by Kathleen Campbell, Jeffrey L. Neul, David N. Lieberman, Elizabeth Berry-Kravis, Tim A. Benke, Cary Fu, Alan Percy, Bernhard Suter, David Morris, Randall L. Carpenter, Eric D. Marsh, Jana von Hehn

“…Methods Participants were randomized to either five days treatment with oral ketamine or matched placebo, followed by a nine-day wash-out period and then crossed-over to the opposite treatment. …”
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Presenting the model of social entrepreneurship in the development of rural tourism in the target villages of Gilan province by Fatemeh Doozandeh Ziabari, hamed fallah tafti, Mir Mohammad Asadi, Mahdi Basouli

“…This emphasis on technology in tourism entrepreneurship is important because new innovations are constantly changing industry dynamics (Yu & Spencer, 2021; Buhalis et al, 2019). …”
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Designing a model for the development of questioning skills based on the school context in primary school students by motahare Khosravi Rad, Ahmad Akbari, Mohammad karimi, Moslem Cherabin

“…In the qualitative section, after conducting interviews and coding processes; as many as 217 open codes, including 11 codes for actors, 37 codes for causal conditions, 12 codes for phenomena, 33 codes for context, 45 codes for intervening conditions, 49 codes for strategy, and 30 codes for Consequences were identified in the initial coding, which decreased after being converted into sub-categories and main categories. Nine main categories were identified as effective strategies, including empowering students; empowering parents; empowering teachers; change in the way of teaching and training; appropriate national planning in order to strengthen students' skills (especially questioning); the development of the intellectual and cultural base of schools; empowering and increasing the power of schools in education; foundation for questioning in schools and the growth of the culture of questioning in society. …”
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Empowering personalized oncology: evolution of digital support and visualization tools for molecular tumor boards by Cosima Strantz, Dominik Böhm, Thomas Ganslandt, Melanie Börries, Patrick Metzger, Thomas Pauli, Andreas Blaumeiser, Alexander Scheiter, Ian-Christopher Jung, Jan Christoph, Iryna Manuilova, Konstantin Strauch, Arsenij Ustjanzew, Niklas Reimer, Hauke Busch, Philipp Unberath

“…These aimed to understand diverse requirements for preparation, implementation, and documentation. Nine semi-structured expert interviews complemented quantitative findings through open discussion. …”
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Characteristics and Outcomes of 79 Patients with an Insulinoma: A Nationwide Retrospective Study in Finland by Elina Peltola, Päivi Hannula, Heini Huhtala, Saara Metso, Ulla Kiviniemi, Martine Vornanen, Juhani Sand, Johanna Laukkarinen, Mirja Tiikkainen, Camilla Schalin-Jäntti, Johanna Arola, Jukka Sirén, Antti Piiroinen, Minna Soinio, Pirjo Nuutila, Mirva Söderström, Hanna Hämäläinen, Leena Moilanen, David Laaksonen, Elina Pirinen, Fia Sundelin, Tapani Ebeling, Pasi Salmela, Markus J. Mäkinen, Pia Jaatinen

“…Retrospective analysis on all adult patients diagnosed with insulinoma in Finland during 1980–2010. Results. Seventy-nine patients were diagnosed with insulinoma over the research period. …”
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People’s knowledge, attitudes, and conflicts with carnivores in central hills, Sri Lanka by Ashan Thudugala, Hem Bahadur Katuwal, Nalindra Laxman, Vishwa Dushmantha, Ravindi Menikrama, Harsha Dissanayake, Chameera Dilshan, Ru-Chuan He, Rui-Chang Quan

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Developing an effective teaching model in order to improve the educational level of schools by Mehdi Mohammadi, fardin Abdollahy, Rafigh Hasani

“…Chew & Cerbin (2021) showed that effective teaching requires solving nine challenges, including changing the mental mindset of students, metacognition and self-regulation, student fear and distrust, prior knowledge, misconceptions, ineffective learning strategies, learning transfer, selective attention limitations and mind effort limitations, and active memory. …”
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Polymorphisms in immunosuppression-related genes are associated with AML by Mingying Li, Mingying Li, Jingjing Ye, Jingjing Ye, Mengyuan Chang, Mengyuan Chang, Lei Feng, Lei Feng, Tingting Liu, Tingting Liu, Di Zhang, Di Zhang, Yuyan Wu, Yuyan Wu, Yuechan Ma, Yuechan Ma, Guangqiang Meng, Guangqiang Meng, Chunyan Ji, Chunyan Ji, Tao Sun, Tao Sun

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Association between non-insulin-based insulin resistance indicators and frailty progression: a national cohort study and mendelian randomization analysis by Hui Tian, Yong-meng Li, Cheng-qiang Wang, Guo-qiang Chen, Ying Lian

“…Baseline TyG index, METS-IR, eGDR, along with the frailty index (FI) over nine years, were calculated. FI trajectories were assessed using group-based trajectory model (GBTM). …”
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體驗教育對建構大學生心理資本之研究 Effect of Experiential Education on College Students’ Psychological Capital Development by 陳淑媛 Shu-Yuan Chen, 許于仁 Yu-Ren Hsu

“…Reflective activities were conducted after each session to promote team development and optimize performance. Nine experiential activities were scheduled over 18 weeks. …”
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Emergency Medicine Palliative Care Access (EMPallA): protocol for a multicentre randomised controlled trial comparing the effectiveness of specialty outpatient versus nurse-led tel... by Jeanne Cho, Michael Hill, Corita R Grudzen, Deborah J Shim, Abigail M Schmucker, Keith S Goldfeld, Lauren Southerland, Jeffrey M Caterino, Marie-Carmelle Elie, Robert Swor, Susan E Cohen, Arum Kim, Joseph Lowy, Jennifer S Scherer, Nancy E Bael, Ellin Gafford, Joshua Lakin, Paige Barker, Angela Chmielewski, Jennifer Kapo, Audrey Tan, Rebecca Yamarik, Susan Salz, Stephen Ryan, Anne Kim, Isabel Castro, Amelia Hargrove, Laura Stuecher, Nora Daut, Juanita Booker-Vaughns, Garrett K Chan, J Nicholas Dionne-odom, Patrick Dunn, Robert Galvin, Ernest A Hopkins III, Margaret M Maguire, Neha Reddy Pidatala, Dawn Rosini, Sally Welsh, Karen Jubanyik, Ada L Rubin, Kei Ouchi, Rebecca Murray, Nicole Tang, Marie Bakitas, Abraham Brody, Caroline Blaum, Mara Flannery, Richard Tamirian, Pamela Marsack, Jennifer Bonito, Romilla Batra, Donna C Sadasivan, Eric David Isaacs, Constance L Kizzie-Gillett, William K Vaughan, Pluscedia G Williams, Angela Young-Brinn

“…The primary outcome will measure change in patient quality of life.Ethics and dissemination Institutional Review Board approval was obtained at all study sites. …”
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Effects of external ankle support on balance control outcomes following muscle fatigue in individuals with ankle instability: A systematic review and meta-analysis by Hanieh KHALILIYAN, Mahmood BAHRAMIZADEH, Amirhossein ZARE, Kavita BATRA, Gabriella NUCERA, Aldo SITIBONDO, Aanuoluwapo AFOLABI, Majid ANSARI, Olayinka ILESANMI, Lukasz SZARPAK, Alireza KHAGHANI, Shahla MOHAJERI, Farhad GHAFFARI, Arash SHARAFATVAZIRI

“…A meta-analysis was performed using Review Manager 5.3 software, calculating standardized mean differences with 95% confidence intervals (CI) for each outcome. Results: Nine crossover studies involving 230 subjects were included. …”
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Within Satisfaction and Distress: Characterizing the First Cultural Transition of Young Talented Cameroonian Footballers by Boris Tachom Waffo, Denis Hauw

“…The study applied the four rigorous criteria to ensure qualitative study trustworthiness: credibility, dependability, confirmability, and transferability (Lincoln & Guba, 1985). Results Nine themes (with their sub-themes) and their relationship were identified: Mental Health Issues (MHI), Context of athletic migration and seven challenges related to: Club and Contract, Team, Pitch, Way of life, Geography, Home country, and High Level Athlete status. …”
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Should the Food and Drug Administration Limit Placebo-Controlled Trials? by Max Goodman, Connor Pedersen

“…It is our belief that the FDA should change its approach and prohibit the use of placebo controls in clinical trials where effective treatments already exist. …”
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