Systematic Administration of B Vitamins Alleviates Diabetic Pain and Inhibits Associated Expression of P2X3 and TRPV1 in Dorsal Root Ganglion Neurons and Proinflammatory Cytokines... by Duan-Duan He, Yu Gao, Shan Wang, Zhong Xie, Xue-Jun Song

“…Treatment of diabetic neuropathic pain (DNP) continues to be a major challenge, and underlying mechanisms of DNP remain elusive. …”
Get full text

Transcriptomic, histological and biochemical analyses of Macrobrachium nipponense response to acute heat stress by Xiao Wu, Yaoran Fan, Jianbin Feng, Keyi Ma, Jiale Li

“…Furthermore, the DEGs in the hepatopancreas were significantly enriched in KEGG pathways including neuroactive ligand-receptor interaction, thyroid hormone synthesis, and ECM-receptor interaction. …”
Get full text

Return to play following craniotomy for non-traumatic brain lesions by Jovanna A. Tracz, Matthew L. Farmer, Mark Hughes, Debraj Mukherjee, Paul M. Brennan

“…Twenty-nine percent of neurosurgeons requested neuroimaging before determining RTP recommendations in this scenario, more commonly in America than Europe (46.7% and 5.0% respectively, p = .006). …”
Get full text

Voluntary Forelimbs Exercise Reduces Immobilization-Induced Mechanical Hyperalgesia in the Rat Hind Paw by Kumiko Ishikawa, Satoshi Oga, Kyo Goto, Junya Sakamoto, Ryo Sasaki, Yuichiro Honda, Hideki Kataoka, Minoru Okita

“…Voluntary exercise is sufficient to protect against neuropathic pain. However, it is unclear whether voluntary exercise reduces immobilization-induced hyperalgesia. …”
Get full text

Daily activity, mood, and quality of life in colorectal cancer patients with chemotherapy‐induced peripheral neuropathy: A mediation effect analysis by Ling‐Chun Lu, Shiow‐Luan Tsay, Sou‐Yi Chang, Chung‐Ming Chen, Chieh‐Yu Liu

“…This was a cross‐sectional relative study in which four instruments were used: the Neuropathic Pain Symptom Inventory was used to measure the severity of CIPN; the Screening of Activity Limitation and Safety Awareness scale was used to evaluate RDA; the Profile of Mood States Short Form was used to assess negative mood; and the Functional Assessment Cancer Center Therapy‐Colorectal scale version 4 was used to evaluate QoL. …”
Get full text

Understanding Cognition, Oxytocin, and Pain in Elders (UCOPE): protocol for a double-blinded cross-over trial in chronic knee osteoarthritis pain by Yenisel Cruz-Almeida, Soamy Montesino-Goicolea, Pedro Valdes-Hernandez, Zhiguang Huo, Roland Staud, Natalie C. Ebner

“…Primary study outcomes include preliminary changes in pain intensity and interference as well as multi-modal assessment batteries including circulating biomarkers and neuroimaging measures. Self-reported and quantitative outcomes will be assessed at baseline, post-intervention periods, and up to a 6-month follow-up period. …”
Get full text

Silent magnetic resonance angiography diagnostic value of intracranial unruptured aneurysms by Bin Lv, Tingyang Zhang, Ning Wang, Lu Liu, Mingyu Li, Meng Li, Mingguang Sun, Xiao Zang, Xinfeng Liu, Rongju Zhang, Xiangyu Cao, Zhihua Du, Jun Wang, Jinhao Lyu, Xueyang Wang, Qi Duan, Fangfang Guo, Xin Lou, Chenglin Tian

“…We included patients diagnosed with unruptured intracranial aneurysms using digital subtraction angiography (DSA) who subsequently underwent S-MRA and 3D-TOF MRA. Two independent neuroimaging and neurointerventional doctors evaluated the DSA images and measured aneurysm dimensions. …”
Get full text

Electroacupuncture Zusanli (ST36) Relieves Somatic Pain in Colitis Rats by Inhibiting Dorsal Root Ganglion Sympathetic-Sensory Coupling and Neurogenic Inflammation by Yi-li Wang, Hai-yan Zhu, Xi-qian Lv, Xing-ying Ren, Ying-chun Peng, Jin-yu Qu, Xue-fang Shen, Ran Sun, Meng-lu Xiao, Hong Zhang, Zhao-hui Chen, Peng Cong

“…It was reported that sprouting of sympathetic nerve fibers into the dorsal root ganglion (DGR) and neurogenic inflammation were related to neuropathic pain, the excitability of neurons, and afferents. …”
Get full text

Towards PErsonalised PRognosis for children with traumatic brain injury: the PEPR study protocol by Jaap Oosterlaan, Marsh Königs, Job B M van Woensel, Marc Engelen, Marjan E Steenweg, Petra J W Pouwels, Cece C Kooper, Hilgo Bruining, Arne Popma, Dennis R Buis, Maayke Hunfeld

“…In addition, the potential added value of advanced neuroimaging data and the use of machine learning algorithms in the development of prognostic models will be assessed.Methods and analysis 210 children aged 4–18 years diagnosed with mild-to-severe TBI will be prospectively recruited from a research network of Dutch hospitals. …”
Get full text

The diagnostic conundrum of late-onset developmental regression in child psychiatry: case series by Shalu Elizabeth Abraham, Sakhardande Kasturi Atmaram, Poornima Khadanga, Nirmalya Mukherjee, Rajendra Kiragasur Madegowda, Harshini Manohar

“…A comprehensive clinical evaluation, laboratory investigations and neuroimaging ruled out any identifiable neurological cause. …”
Get full text

Research status and trends of functional magnetic resonance imaging technology in the field of acupuncture: a bibliometric analysis over the past two decades by Zhongke Wang, Lu Chen, Tianyu Jiang, Qi Zhang, Jinying Zhao, Fuchun Wang

“…Evidence-based Complementary and Alternative Medicine is the journal with the most publications, while Neuroimage is the co-cited journal with the highest citation frequency. …”
Get full text

Posterior reversible encephalopathy syndrome in a young male with IgA nephropathy and chronic kidney disease: a case report from the Maldives by Rajib Kumar Dey, Gunjan Khadka, Shifa Ishaq, Aishath Zeena Abdul Jaleel, Aminath Shafeenaz Moosa, Saifullah Muslim, Ali Nazeem

“…Uremia in CKD patients is also one of the factors for developing PRES. Neuroimaging findings involve posterior white matter edema commonly affecting the parietal and occipital lobes. …”
Get full text

Artificial Intelligence in Pediatric Epilepsy Detection: Balancing Effectiveness With Ethical Considerations for Welfare by Marina Ramzy Mourid, Hamza Irfan, Malik Olatunde Oduoye

“…Specific methods, like EEG‐based AI for detecting interictal discharges, showed high specificity (93.33%–96.67%) and sensitivity (76.67%–93.33%), while neuroimaging approaches using rs‐fMRI and DTI reached up to 97.5% accuracy in identifying microstructural abnormalities. …”
Get full text

The White Matter Functional Abnormalities in Patients with Transient Ischemic Attack: A Reinforcement Learning Approach by Huibin Ma, Zhou Xie, Lina Huang, Yanyan Gao, Linlin Zhan, Su Hu, Jiaxi Zhang, Qingguo Ding

“…These results support the role of WM functional neural activity as a potential neuromarker in classifying patients with TIA and offer novel insights into the underlying mechanisms in patients with TIA from the perspective of WM function.…”
Get full text

Transcriptomic Profile Analysis of Brain Tissue in the Absence of Functional TRPM8 Calcium Channel by Erick B. Saldes, Alexandra Erdmier, Jai Velpula, Timothy E. Koeltzow, Michael X. Zhu, Swapna Asuthkar

“…Notably, TRPM8 has been implicated in neuropathic pain, migraines, and neurodegenerative diseases such as Parkinson’s disease. …”
Get full text

Active versus sham transcranial direct current stimulation (tDCS) as an adjunct to varenicline treatment for smoking cessation: Study protocol for a double-blind single dummy rando... by Laurie Zawertailo, Helena Zhang, Noreen Rahmani, Tarek K Rajji, Peter Selby

“…Furthermore, the addition of longitudinal neuroimaging can shed light on neural circuitry changes that might occur as a result of brain stimulation, furthering our understanding of tDCS in addiction treatment.…”
Get full text

Multimodal smoking cessation treatment combining repetitive transcranial magnetic stimulation, cognitive behavioral therapy, and nicotine replacement in veterans with posttraumatic... by Jonathan R Young, Carri S Polick, Andrew M Michael, Moritz Dannhauer, Jeffrey T Galla, Mariah K Evans, Addison Troutman, Angela C Kirby, Michelle F Dennis, Claire W Papanikolas, Zhi-De Deng, Scott D Moore, Eric A Dedert, Merideth A Addicott, Lawrence G Appelbaum, Jean C Beckham

“…The success of iTBS will be evaluated through self-reported nicotine use, cravings, withdrawal symptoms, and abstinence following quit date (confirmed by bioverification) along with evaluation for target engagement through neuroimaging changes, specifically connectivity differences between the insula and other regions of interest.…”
Get full text

Clinical trials since 2020 of rapid anti-suicidal ideation effects of ketamine and its enantiomers: a systematic review by Sumra Sajid, J. John Mann, Michael F. Grunebaum

“…After screening, 14 RCTs met the inclusion criteria which required clinically significant SIB among participants, ketamine or one of its enantiomers as an anti-SIB treatment, and SIB as an outcome. We excluded neuroimaging studies, meta-analyses, reviews, and case reports. …”
Get full text

Association of cortical macrostructural and microstructural changes with cognitive performance and gene expression in subcortical ischemic vascular disease patients with cognitive... by Jing Huang, Runtian Cheng, Xiaoshuang Liu, Li Chen, Tianyou Luo

“…Moreover, the associations between the significant neuroimaging values and the cognitive scores and gene expression values from Allen Human Brain Atlas database were evaluated using partial least squares regression and partial correlation analysis. …”
Get full text

Crotonylation-Related Prognostic Model of Esophageal Squamous Cell Carcinoma Based on Transcriptome Analysis and Single-Cell Sequencing Analysis by Lin RY, Chen RP, Lin FQ

“…FABP3 and FAM189A2 were enriched in neuroactive ligand-receptor interaction and ribosome terms. …”
Get full text