Successful Treatment of Actinic Keratosis with Kanuka Honey by Saras Mane, Joseph Singer, Andrew Corin, Alex Semprini

“…Actinic keratoses form as rough, scaly plaques on sun-exposed areas; they can be an important step in premalignant progression to squamous cell cancer of the skin. Currently, pharmacological treatments consist of topical immunomodulatory agents with poor side effect profiles. …”
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Exploring the anticancer potential of Hewittia malabarica through phytochemical analysis and molecular docking study by Shiji Thozhukkad Moosaripparambil, Kannan Vadakkadath Meethal

“…Abstract Natural resources provide valuable medicinal components that are highly sought after as alternatives to synthetic drugs for treating serious diseases like cancer. Hewittia malabarica, a creeper native to India, is recognized for its exceptional medicinal properties. …”
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The homologous recombination factors BRCA2 and PALB2 interplay with mismatch repair pathways to maintain centromere stability and cell viability by Emily Graham, Lucia Rampazzo, Chin Wei Brian Leung, Jacob Wall, Emőke Zsanett Gerőcz, Mikhail Liskovykh, Nikolay Goncharov, Xanita Saayman, Ramazan Gundogdu, Masato T. Kanemaki, Hiroshi Masumoto, Vladimir Larionov, Natalay Kouprina, Fumiko Esashi

“…We find that BRCA2, but not PALB2, is essential for maintaining a human artificial chromosome. In native chromosomes, BRCA2 ensures CENP-A occupancy and prevents DNA fragility at centromeres. …”
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Moringa oleifera: A review on nutritive importance and its medicinal application by Lakshmipriya Gopalakrishnan, Kruthi Doriya, Devarai Santhosh Kumar

“…Moringa oleifera, native to India, grows in the tropical and subtropical regions of the world. …”
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Hemoglobin: A Nitric-Oxide Dioxygenase by Paul R. Gardner

“…Members of the hemoglobin superfamily efficiently catalyze nitric-oxide dioxygenation, and when paired with native electron donors, function as NO dioxygenases (NODs). …”
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Engineered Bacteria for Disease Diagnosis and Treatment Using Synthetic Biology by Kai Jin, Yi Huang, Hailong Che, Yihan Wu

“…The application of microbial therapies in cancer, intestinal diseases, and metabolic disorders underscores their significant potential. …”
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Corallocarpus glomeruliflorus: Pharmacological potential revealed by phytochemical and in silico investigations by Fatima Saleh Naji Bin-Asal, Adel A.M. Saeed, Abdul-Rahman Alawi Bin Yahia

“…Corallocarpus glomeruliflorus (CGP), a plant native to Yemen, has been traditionally used for the management of various health conditions, including cancer, inflammation, and diabetes. …”
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Number of Endoscopic Retrograde Cholangiopancreatography Procedures Required for Short Biliary Cannulation Time by Koichiro Mandai, Koji Uno, Yasutoshi Fujii, Takuji Kawamura, Kenjiro Yasuda

“…Our findings suggested that an ERCP experience of ≤300 procedures and malignant biliary stricture due to pancreatic cancer were associated with prolonged biliary cannulation time.…”
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Geosmithia Species in Florida: Common Fungal Symbionts of Wood-Boring Bark Beetles by Yin-Tse Huang, Jiri Hulcr

“…Most Geosmithia species do no harm to host trees, but the canker-causing Geosmithia morbida and its beetle vector, the walnut twig beetle, cause the disease complex known as thousand cankers disease on walnut trees. …”
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THE CONCEPT OF ‘ALA BỤ ALA’: A SIGNAL FOR IGBO EXTINCTION by CYPRIAN CHIDOZIE EZE, MABEL NKECHINYERE EZE

“…The aim of this paper is to expose the danger of this type of attitude demonstrated by some Igbo indigenes to the continuity of Igbo language and culture. …”
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Complexation by γ-cyclodextrin as a way of improving anticancer potential of sumanene by Artur Kasprzak, Agnieszka Żuchowska, Hidehiro Sakurai

“…Improved pharmacokinetic (ADME-Tox) properties for sumanene@γCD and sumanene@HP-γCD complexes in comparison to native sumanene were also supported by in sillico modeling studies. …”
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Induction of Tolerance via the Sublingual Route: Mechanisms and Applications by Philippe Moingeon, Laurent Mascarell

“…The oral immune system comprises various antigen-presenting cells, including Langerhans cells, as well as myeloid and plasmacytoid dendritic cells (DCs) with a distinct localisation in the mucosa, along the lamina propria and in subepithelial tissues, respectively. In the absence of danger signals, all these DC subsets are tolerogenic in that they support the differentiation of Th1- and IL10-producing regulatory CD4+ T cells. …”
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Systematic protein–protein interaction mapping for clinically relevant human GPCRs by Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

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Geosmithia Species in Florida: Common Fungal Symbionts of Wood-Boring Bark Beetles by Yin-Tse Huang, Jiri Hulcr

“…Most Geosmithia species do no harm to host trees, but the canker-causing Geosmithia morbida and its beetle vector, the walnut twig beetle, cause the disease complex known as thousand cankers disease on walnut trees. …”
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Evaluation of the Risk of Recurrence in Patients with Local Advanced Rectal Tumours by Different Radiomic Analysis Approaches by Alaa Khadidos, Adil Khadidos, Olfat M. Mirza, Tawfiq Hasanin, Wegayehu Enbeyle, Abdulsattar Abdullah Hamad

“…In deep learning, we built a 16-layer convolutional neural network model, driven by a 2D MRI image database comprising both the native images and the bounding box corresponding to each image.…”
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Analysis of different therapeutic schemes combining cyclophosphamide and doublestranded DNA preparation for eradication of Krebs-2 primary ascites in mice by E. A. Potter, E. V. Dolgova, A. M. Minkevich, V. P. Nikolin, N. A. Popova, Ya. R. Efremov, S. I. Baiborodin, V. A. Rogachev, A. S. Proskurina, A. V. Kozel, O. S. Taranov, V. V. Omigov, E. I. Vereschagin, D. B. Petrov, A. A. Ostanin, E. R. Chernykh, N. A. Kolchanov, S. S. Bogachev

“…Thus, we developed the concept for treating ascites form of Krebs-2 cancer, which allows elimination of the primary ascites.…”
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Reporting and representation of participant race and ethnicity in phase III clinical trials for solid tumors by Tianyi Wang, Dinorah J Villanueva, Ambily Banerjee, Dina Gifkins

“…Compared with SEER data, the percentages were lower for Asian/Pacific Islander across all cancers, Black/African American in breast and prostate cancers, American Indian or Alaska Native in colorectal, breast, and prostate cancers in US solely trials.Conclusions Reporting and enrollment of racial and ethnic minorities in trials remain inadequate but improving. …”
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Metabolites Profiling of Manilkara mabokeensis Aubrév Bark and Investigation of Biological Activities by Xavier Worowounga, Rami Rahmani, Armel-Frederic Namkona, Sylvie Cazaux, Jean-Laurent Syssa-Magalé, Hubert Matondo, Jalloul Bouajila

“…Manilkara mabokeensis Aubrév is a tree that belongs to the Sapotaceae family, native to the tropical forest in Latin America, Asia, Australia, and Africa. …”
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Potential of Louhan fish (Amphilophus labiatus) as a local fishery pest in Lake Toba North Sumatra as a source omega 3 and 6 fatty acids by Pandiangan Maruba, Sihombing Dewi Restuana, Daniela Connie, Sibuea Posman, Tampubolon Sanggam Dera Rosa, Sitohang Apul, Sitanggang Lasmianna

“…Identifying the oil of Louhan fish (Amphilophus labiatus), which are now considered a nuisance and a danger to the native fish of Lake Toba, as a source of omega 3 and omega 6 fatty acids is the aim of the study. …”
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Comparison of Antioxidant and Alpha-Glucosidase Inhibitory Properties of Moringa peregrina and Ferulago carduchorum Leaf Extracts and Microencapsulation of Superior Plant by Shiva Nouri, Maryam Moslehishad, Seyede Marzieh Hosseini, Mina Etemadi

“…Today, medicinal plants have a crucial role in treating diseases such as diabetes and cancer. These plants do not impose any side effects owing to their bioactive compounds in comparison with chemical drugs. …”
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