Prevalence, Spectrum, and Outcomes of Single Coronary Artery Detected on Coronary Computed Tomography Angiography (CCTA) by Rashid Al Umairi, Maryam Al-khouri

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Protocol for a multicentre, prospective, open-label, randomised controlled trial to compare PROs and safety outcomes between preoperative and postmastectomy radiotherapy in locally... by Li Zhang, Jiong Wu, Guangyu Liu, Shuang Hao, Jianjing Hou, Changming Zhou, Yifeng Hou, Keda Yu, Zhen Hu, Genhong Di, Zhi Min Shao, Xiaoli Yu

“…Approval for this study was provided by the independent ethics committee and institutional review board of Fudan University Shanghai Cancer Centre. …”
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Impact of the Mediterranean Diet on Patients With Psoriasis: Protocol for a Randomized Controlled Trial by Javier Perez-Bootello, Emilio Berna-Rico, Carlota Abbad-Jaime de Aragon, Ruth Cova-Martin, Leticia Goni, Asuncion Ballester-Martinez, Pedro Jaen-Olasolo, Nehal Mehta, Joel M Gelfand, Miguel Angel Martinez-Gonzalez, Alvaro Gonzalez-Cantero

“…This study protocol was approved by the Institutional Review Board of the Hospital Ramón y Cajal (Madrid) in July 2023. …”
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Helping people with psychosis with a low-cost intervention DIALOG+: protocol for the economic evaluation in a randomised control trial in India and Pakistan by Victoria Jane Bird, Sara Evans-Lacko, Lakshmi Venkatraman, Padmavati Ramachandran, Ashar Muhammad Malik, Renata Peppl, Sana Zehra Zehra Sajun, Onaiza Qureshi, Krishna Priya, Hufsa Sarwar

“…The economic evaluation will support efforts to scale up low-cost healthcare interventions such as DIALOG+ to rural and unserved areas, which is otherwise challenging in the resource-constrained health systems in many LMICs.Conclusion The evidence on the cost-effectiveness of DIALOG+ will contribute to efforts to improve community-based care and the quality of life for millions of people suffering from mental health problems in India and Pakistan who experience psychosis.Ethics and dissemination This study is approved by the Queen Mary Ethics of Research Committee (UK), Institutional Ethics Committee of SCARF (India), IRD’s Independent Institutional Review Board (IRD_IRB_2021_01_005) (Pakistan), Karawan-e-Hayat Management Committee (Institutional Approval) (Pakistan), Jinnah Postgraduate Medical Centre Research Committee (NO.F.2-81/2021-GENL/60224/JPMC) (Pakistan), Aga Khan’s Ethics Research Committee (2021-5933-17533) (Pakistan) and National Bio-Ethics Committee, Pakistan (Ref: No.4–87/NBC-774/22/2037 Date: 17 May 2022).The findings of this research will be widely disseminated through research publications and engagement with the communities and the healthcare providers in the public and not-for-profit sectors.Trial registration number ISRCTN13022816.…”
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Personalised Lung Cancer Screening (PLuS) study to assess the importance of coexisting chronic conditions to clinical practice and policy: protocol for a multicentre observational... by Yi Guo, Dongyu Zhang, Rafael Meza, Jihyoun Jeon, Dejana Braithwaite, Gerard A Silvestri, Michael K Gould, Jiang Bian, Bruno Hochhegger, Shama D Karanth, Christopher G Slatore, Martin Tammemagi, Mattthew Schabath, Meghann Wheeler, Frederic J Kaye

“…To our knowledge, this is the first study to combine observational data and simulation models to estimate the long-term impact of LCS with LDCT.Ethics and dissemination The study was approved by the Kaiser Permanente Southern California Institutional Review Board and VA Portland Health Care System. The results will be disseminated through publications and presentations at national and international conferences. …”
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Retrospective observational cohort study of premature neonates screened for ROP with 7 years of follow-up assessing the visual outcomes and adequacy of preschool visual screening by Emma McAllister, Ruth Hamilton, Eoghan Millar, Alasdair Innes Simpson, Jacqueline Wright

“…A total of 111 (50%) of these children had been referred to HES nationally. 103 were referred within the health board where ROP screening took place; of these, 47% (48/103) were referred from the See4School programme, 31% (31/103) from paediatric clinics, 13% (13/103) from primary care and 11% (11/103) from community optometrists. 42 of these 103 referrals (41%) to HES had occurred before the age (3½ years) when children became eligible for See4School screening. …”
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Special issue: Proceedings of the 15th ISIC - The Information Behaviour Conference, Aalborg, Denmark, August 26-29, 2024

“…Garwood The reading practices of people with neuropsychiatric disabilities: a review of library and information science literature Katarina Hagberg, Karin Lundin, Anna Lundh, Åse Hedemark Representational exchange and edgework: towards theorising the coping with fragmentary information Isto Huvila Digital health applications and health literacy: an explorative analysis Aylin Imeri, Sabrina Schorr, Sebastian Merkel To share or not to share? …”
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Effectiveness of using implementation frameworks to facilitate the implementation of a stroke management guideline in the traditional Chinese medicine hospitals in China: protocol... by Zhuo Chen, Yefeng Cai, Wenjun He, Yiyuan Cai, Lingrui Liu, Qing Zhao, Sensen lv, Dong (Roman) Xu, Chun Hao, Lanping Zhang, Pengfei Guo, Yuning Shi

“…Additionally, a cost-effectiveness analysis will be conducted to assess the economic feasibility of the implementation strategies.Ethics and dissemination This trial has been approved by the Institutional Review Board of Southern Medical University (approval number: #202261) and follows all relevant ethical guidelines for research involving human participants. …”
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Prospective multicentre randomised trial comparing the efficacy and safety of single-anastomosis duodeno–ileal bypass with sleeve gastrectomy (SADI-S) versus Roux-en-Y gastric bypa... by Delphine Maucort-Boulch, Maud Robert, Tigran Poghosyan, Dominique Delaunay, Elise Pelascini, Sylvain Iceta, Adrien Sterkers, Charles Barsamian, Litavan Khamphommala, Sylvie Bin Dorel, Sebastien Czernichow, Emmanuel Disse

“…With a drop-out rate of 10%, it will be necessary to include 183 patients per group.Ethics and dissemination The study was approved by Institutional Review Board of Centre Hospitalier Universitaire Morvan (CPP1089-HPS1). …”
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Randomised cross-over trial of vildagliptin and pioglitazone as add-on therapy in patients with type 2 diabetes: predicting Which One is Right Here (WORTH) study protocol by Yannan Jiang, Tony R Merriman, Rui Qian Yeu, Rebecca Brandon, Dale Griffiths, Kate Smallman, Allan Moffitt, Glenn Doherty, Ryan Paul, Jennie Harré Hindmarsh, Kerry Macaskill-Smith, Brandon Orr-Walker, Rinki Murphy

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Diffuse Reflectance Spectrophotometers Based on C12880MA and C11708MA Mini-Spectrometers Hamamatsu by V. A. Firago, N. V. Levkovich, K. I. Shuliko

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Does semaglutide reduce alcohol intake in Danish patients with alcohol use disorder and comorbid obesity? Trial protocol of a randomised, double-blinded, placebo-controlled clinica... by Jens Juul Holst, Tina Vilsbøll, Claus Thorn Ekstrøm, Helene Benveniste, Nora D Volkow, Anders Fink-Jensen, Gitte M Knudsen, Mette Kruse Klausen, Tugba Kuzey, Julie Niemann Pedersen, Signe Keller Justesen, Line Rasmussen, Ulla B Knorr, Graeme Mason, George Koob

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Study protocol for key interventions to improve the follow-up adherence postcervical precancerous lesion treatment in Ethiopia: a pragmatic randomised controlled trial by Adamu Addissie, Eva Johanna Kantelhardt, Eric Sven Kroeber, Sefonias Getachew, Muluken Gizaw, Abel Shita, Alemnew Destaw, Eyerusalem Getachew, Miresa Midaksa, Sophie Rossner

“…Descriptive statistics, χ2 test (Fisher’s exact test), binary logistic regression analysis and intention-to-treat will be used to describe and interpret the results.Ethics and dissemination The trial protocol has been approved by the institutional review board of Addis Ababa University with protocol number (008/24/SPH). …”
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Determining the incidence, risk factors and biological drivers of irritable bowel syndrome (IBS) as part of the constellation of postacute sequelae of SARS-CoV-2 infection (PASC) o... by Erika Austhof, Kelly M Heslin, Xiaoxiao Sun, Kristen Pogreba Brown, Caitlyn M McFadden, Caroline Scranton, Ivan Vujkovic-Cviji, Dominic Rodriguez, Laura Falk, Gayatri Arani, Victoria Obergh, Kate Bessey, Kerry Cooper

“…All laboratory data will be linked with in-depth epidemiologic data on demographics, symptoms and chronic conditions.Ethics and dissemination This study involves human participants and was approved by the University of Arizona Institutional Review Board (IRB (#00002332) and has been deemed minimal risk. …”
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Open-label dose-extending placebos for opioid use disorder: a protocol for a randomised controlled clinical trial with methadone treatment by Annabelle M Belcher, Thomas O Cole, Aaron D Greenblatt, Stephen W Hoag, David H Epstein, Michael Wagner, Amy S Billing, Ebonie Massey, Kristen R Hamilton, Zofia K Kozak, Christopher J Welsh, Eric Weintraub, Emerson M Wickwire, Eric D Wish, Ted J Kaptchuk, Luana Colloca

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Tadalafil treatment for fetuses with early-onset growth restriction: a protocol for a multicentre, randomised, placebo-controlled, double-blind phase II trial (TADAFER IIb) by Hiroaki Tanaka, Yasuhiro Tanaka, Yoichi Aoki, Masayuki Endo, Tomoaki Ikeda, Shintaro Maki, Masafumi Nii, Kayo Tanaka, Satoshi Tamaru, Toru Ogura, Yuki Nishimura, Tomomi Kotani, Akihiko Sekizawa, Masahiko Nakata, Koji Nakamura, Kenji Nagao, Ichiro Yasuhi, Hiroshi Kawamura, Sho Takakura, Mayumi Kotera, Takafumi Ushida, Norihiko Kikuchi, Tadatsugu Kinjo, Mayumi Takano, Sachie Suga, Michi Kasai, Osamu Yasui, Yuka Maegawa, Shigeru Aoki, Yoshio Yoshida

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Emergency Medicine Palliative Care Access (EMPallA): protocol for a multicentre randomised controlled trial comparing the effectiveness of specialty outpatient versus nurse-led tel... by Jeanne Cho, Michael Hill, Corita R Grudzen, Deborah J Shim, Abigail M Schmucker, Keith S Goldfeld, Lauren Southerland, Jeffrey M Caterino, Marie-Carmelle Elie, Robert Swor, Susan E Cohen, Arum Kim, Joseph Lowy, Jennifer S Scherer, Nancy E Bael, Ellin Gafford, Joshua Lakin, Paige Barker, Angela Chmielewski, Jennifer Kapo, Audrey Tan, Rebecca Yamarik, Susan Salz, Stephen Ryan, Anne Kim, Isabel Castro, Amelia Hargrove, Laura Stuecher, Nora Daut, Juanita Booker-Vaughns, Garrett K Chan, J Nicholas Dionne-odom, Patrick Dunn, Robert Galvin, Ernest A Hopkins III, Margaret M Maguire, Neha Reddy Pidatala, Dawn Rosini, Sally Welsh, Karen Jubanyik, Ada L Rubin, Kei Ouchi, Rebecca Murray, Nicole Tang, Marie Bakitas, Abraham Brody, Caroline Blaum, Mara Flannery, Richard Tamirian, Pamela Marsack, Jennifer Bonito, Romilla Batra, Donna C Sadasivan, Eric David Isaacs, Constance L Kizzie-Gillett, William K Vaughan, Pluscedia G Williams, Angela Young-Brinn

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Effectiveness of case-area targeted interventions including vaccination on the control of epidemic cholera: protocol for a prospective observational study by Lauren D'Mello-Guyett, Ruwan Ratnayake, Andrew S Azman, Yap Boum, Francesco Checchi, W John Edmunds, Placide Okitayemba Welo, Nicolas Peyraud, Iza Ciglenecki, Etienne Gignoux, Maria Lightowler, Primitive Gakima, Jean Patrick Ouamba, Joseph Amadomon Sagara, Rollin Ndombe, Nana Mimbu, Alexandra Ascorra, Elisabeth Mukamba Musenga, Berthe Miwanda, Francisco Luquero, Klaudia Porten, Flavio Finger, Miriam Alia, Bachir Assao, Catherine Bachy, Rob D'hondt, Karl Njuwa Fai, Caroline Henry-Ostian, Abdoul-Moumouni Issa-Soumana, Danish Malik, Herbert Mutubuki, Rodrigue Ntone, Isabella Panunzi, Issaka Soumana, Oumar Touré, Mamady Traore

“…The DRC and Niger-specific versions have been approved by the respective national ethics review boards. Approvals are in process for Cameroon and Zimbabwe. …”
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Editorial by Joanna Krasodomska, Nadia Albu, Anna Szychta

“…On behalf of the entire ZTR Editorial Team, we wish all authors, reviewers, members of the Editorial Board, and readers of ZTR a lot of health, happiness, and peace, as well as numerous professional successes in 2025. …”
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ACCOUNTING REGULATIONS AND STANDARDS: THE DEVELOPMENT AND BENEFITS OF IFRS IN NIGERIA by Majeed Ajibola IBRAHIM, Adedeji Daniel GBADEBO

“… International Financial Reporting Standards (IFRS) - a set of high-quality standards introduced by the International Accounting Standards Board in 2001 and have since been adopted by many developed countries for their accounting information system. …”
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