Chemogenomic Screening in a Patient‐Derived 3D Fatty Liver Disease Model Reveals the CHRM1‐TRPM8 Axis as a Novel Module for Targeted Intervention by Sonia Youhanna, Aurino M. Kemas, Shane C. Wright, Yi Zhong, Britta Klumpp, Kathrin Klein, Aikaterini Motso, Maurice Michel, Nicole Ziegler, Mingmei Shang, Pierre Sabatier, Aimo Kannt, Hongda Sheng, Nuria Oliva‐Vilarnau, Florian A. Büttner, Brinton Seashore‐Ludlow, Jonas Schreiner, Maike Windbergs, Martin Cornillet, Niklas K. Björkström, Andreas J. Hülsmeier, Thorsten Hornemann, Jesper V. Olsen, Yi Wang, Roberto Gramignoli, Michael Sundström, Volker M. Lauschke

“…Abstract Metabolic dysfunction‐associated steatohepatitis (MASH) is a leading cause of chronic liver disease with few therapeutic options. To narrow the translational gap in the development of pharmacological MASH treatments, a 3D liver model from primary human hepatocytes and non‐parenchymal cells derived from patients with histologically confirmed MASH was established. …”
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Estimation of population structure in emmer wheat germplasm conserved in the National Genebank of India by Jatin Tanwar, Sandhya Tyagi, Shivani Sharma, Preeti Jakhar, Gaurav Kumar, Sherry R. Jacob, Amit Kumar Singh, Shailendra K. Jha, Jyoti Kumari

“…Based on the present study, it is evident that cultivated emmer wheat showed low genetic diversity and a narrow genetic base. This might be due to limited cultivation in small pockets and emphasizes a need to broaden the genetic base of emmer wheat genetic resources for enhanced utilization.…”
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DEVELOPMENT OPPORTUNITIES OF POLISH FARMS by Monika Juchniewicz, Łukasz Podstawka

“…On the otherhand, in holdings with mixed crop and animal production, with permanent crops and specialised in grassland animal husbandry, there was a narrower reproduction of fixed assets.The analysis of agricultural holdings run by natural persons showed that the accumulation rate and the reproduction rate increased along with the economic size of agricultural holdings.Farms with an economic size of up to EUR 25 thousand SO in the studied period recorded a negative accumulation rate and reproduction rate. …”
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Evolutionary Genomics Provides Insights Into Endangerment and Conservation of a Wild Apple Tree Species, Malus sieversii by Jian Zhang, Fang‐Yuan Zhao, Hong‐Xiang Zhang

“…Malus sieversii, a relict broad‐leaf forest tree found in arid Central Asian mountains, has a narrow and fragmented distribution and is classified as an endangered species in China. …”
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Silicon and Phosphorus Co-doping of Aluminium Nitride Nanotube (SiP-AlNNT) as Sensors for Polycyclic Aromatic Hydrocarbon Fuel Pollutants: A Computational Approach by Musa Runde, Uzairu Muhammad Sada, Friday Odey Izachi, Odey S. Eburu, Anthony M.S. Pembere

“…This is first suggested by the most narrowed energy gap (Egap ¼ 2.704 eV), strongest adsorption (Eads ¼ ¡1.54 eV), and highest polarity (dipole moment ¼ 11.29 D). …”
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Integrative transcriptome profiling for identifying ALS potential treatment using the drug repurposing approach by Navid Kashani, Amir Sabbaghian, Fatemeh EmamiPari, Mohammad Khalili Gorjimahalleh, Mahdi Aalikhani

“…This approach also would help narrow down the options to more suitable targets and economically viable treatments.…”
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Droga do Raciborza: grabież bibliotek i archiwów Europy przez Sztab Operacyjny Rosenberga (Einsatzstab Reichsleiter Rosenberg). Część II (przeł. Tomasz Olszewski) by Patricia Kennedy Grimsted

“…Warto odnotować interesujące współzawodnictwo w zdobywaniu materiału bibliotecznego i archiwalnego między jednostkami i agencjami nazistowskimi reprezentującymi różne interesy (wywiad, propaganda, instytucje naukowe). Wiele ze zrabowanych książek nie trafiło po wojnie do ich właścicieli.…”
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Constraints on the Variation of the Fine-structure Constant at 3 < z < 10 with JWST Emission-line Galaxies by Linhua Jiang, Shuqi Fu, Feige Wang, Sarah E. I. Bosman, Zheng Cai, Hyunsung D. Jun, Zhiwei Pan, Fengwu Sun, Jinyi Yang, Huanian Zhang

“…The galaxy sample consists of 621 high-quality spectra with strong and narrow [O  iii ] λλ 4959,5007 doublet emission lines from 578 galaxies, including 232 spectra at z  > 5. …”
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Real-time monitoring by interferometric light microscopy of phage suspensions for personalised phage therapy by Benjamine Lapras, Camille Merienne, Emma Eynaud, Léa Usseglio, Chloé Marchand, Mathieu Médina, Camille Kolenda, Thomas Briot, Frédéric Laurent, Fabrice Pirot, PHAGEinLYON

“…Particle concentration was linearly correlated with phage infectious titre (R2 > 0.97, slope: 3 particles/plaque forming units (PFU)) at various degrees of purification, allowing to approximate the infectious titre for suspensions ≥ 3 × 108 PFU/mL, thereby encompassing most therapeutic doses. Purification narrowed and homogenised particle distribution while maintaining therapeutic concentrations. …”
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Narracja parametryczna by David Bordwell

“… Bordwell stwierdza, że narracja parametryczna nie jest związana z żadną szkołą narodową, okresem historii czy gatunkiem filmu. Wydaje się, że jego normom brakuje konkretności historycznej, która cechuje np. narrację klasyczną czy narrację kina artystycznego. …”
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Evaluation of Anterior Segment’s Structures in Tilted Disc Syndrome by Ercan Ozsoy, Abuzer Gunduz, Ersin Ersan Demirel, Tongabay Cumurcu

“…We determined that CCT was thinner, CV was less, and ACA was narrower in patients with TDS. There are some changes in the anterior segment of the eyes with tilted disc.…”
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Kinetic origin of hysteresis and the strongly enhanced reversible barocaloric effect by regulating the atomic coordination environment by Zi-Bing Yu, Hou-Bo Zhou, Feng-Xia Hu, Jian-Tao Wang, Fei-Ran Shen, Lun-Hua He, Zheng-Ying Tian, Yi-Hong Gao, Bing-Jie Wang, Yuan Lin, Yue Kan, Jing Wang, Yun-Zhong Chen, Ji-Rong Sun, Tong-Yun Zhao, Bao-Gen Shen

“…First-principles calculations demonstrate that substituting In atoms at Ge sites rather than Co sites results in a lower energy barrier, indicating a narrower hysteresis for the former. Combining neutron powder diffraction (NPD) with magnetic and calorimetric measurements completely verified the theoretical prediction. …”
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Secular religions and the religious/secular divide by Tamás Nyirkos

“…Nazywanie ich świeckimi będzie tylko pomagało im aby odróżniać się jako bardziej „obiektywne”, „realistyczne” czy „naukowe” niż tradycyjne systemy religijne, co najprawdopodobniej nie jest prawdą. …”
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Saúde mental de mulheres sobreviventes a tentativas de feminicídio // Mental health of women survivors of feminicide attempts by Isabella Parreiras Andrade, Tatiana Machiavelli Carmo Souza

“…Em etapa seguinte, uma participante narrou, por meio de entrevista, sua trajetória enquanto sobrevivente. …”
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Updated Nematocyst Types in Tentacle of Venomous Box Jellyfish, <i>Chironex indrasaksajiae</i> _{(Sucharitakul, 2017)} and <i>Chiropsoides buitendijki</i> <sub>(Horst, 1907... by Thippawan Yasanga, Klintean Wunnapuk, Rochana Phuackchantuck, Lakkana Thaikruea, Thunyaporn Achalawitkun, Purinat Rungraung, Sineenart Santidherakul

“…Conversely, <i>C. buitendijki</i> showed a narrower size range, 72.17 µm to 98.37 µm in length and 10.73 µm to 16.48 µm in width, based on multiple individuals. …”
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Selective light olefin synthesis with high ethylene abundance via CO2 hydrogenation over (Ga-In)2O3/SSZ-13 catalysts by Yasemen Kuddusi, Laura Piveteau, Mounir Mensi, Daniel C. Cano-Blanco, Andreas Züttel

“…Inspired by the promising catalytic activity of Ga2O3-based catalysts in alkane dehydrogenation, this study reveals that optimizing Ga content in the GaxIn2-xO3/SSZ-13 catalytic system can narrow the product distribution toward light olefins. …”
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A Reading Range- and Frequency-Reconfigurable Antenna for Near-Field and Far-Field UHF RFID Applications by Chenyang Song, Zhipeng Wu

“…Moreover, each operation mode has a narrow frequency band, which means it can operate without violating different countries’ radio frequency policy and reduce the design difficulty of designing multiple versions of a reader. …”
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ALP-ine quests at the LHC: hunting axion-like particles via peaks and dips in t t ¯ $$ t\overline{t} $$ production by Afiq Anuar, Anke Biekötter, Thomas Biekötter, Alexander Grohsjean, Sven Heinemeyer, Laurids Jeppe, Christian Schwanenberger, Georg Weiglein

“…Finally, we compare the limits obtained from the t t ¯ $$ t\overline{t} $$ searches to existing experimental bounds from LHC searches for narrow di-photon resonances, from measurements of the production of four top quarks, and from global analyses of ALP–SMEFT interference effects.…”
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Discerning Natural and Anthropogenic Factors Driving the Variation of Estuarine CH4 and N2O by Zhengping Chen, Liuqian Yu, Qichun Yang, Qixing Ji

“…., N2O varied within a narrower range than CH4). By presenting and analyzing the 2-year time series of estuarine CH4 and N2O with a high temporal resolution under complex natural and anthropogenic forcing, this study underscores the importance of human influence on greenhouse gas inventories and emissions.…”
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Dam-breach process simulation and risk assessment of outburst flood induced by the Tangjiashan landslide-dammed lake by Junxue Ma, Chong Xu, Jian Chen

“…The proposed numerical simulations highlight significant variations in OF dynamics across different terrain types, with narrow sections experiencing faster flood progression and higher water depths. …”
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