Identification of candidate genes involved in Zika virus-induced reversible paralysis of mice by John D. Morrey, Venkatraman Siddharthan, Hong Wang, Alexandre L. R. Oliveira, Keiichiro Susuki, Rakesh Kaundal, Sara M. Freeman, Aaron J. Thomas, Naveen Duhan, Nathan G. Corry

“…To address this, we performed bioinformatics analysis on spinal cord RNA to identify 2058 differentially expressed genes (DEGs) that were altered during paralysis and then normalized after paralysis. Of these “biphasic” DEGs, 951 were up-regulated and 1107 were down-regulated during paralysis, followed by recovery. …”
Get full text

Effect of forging sequence and heat treatment on microstructure of high-duty power-plant shaft made of Cr-Mo ultra-high strength steel by Skubisz P., Lisiecki Ł.

“…The material was studied in the as-forged, normalized and heat-treated states to observe the behavior of the hot-formed material and the effects of cooling conditions on the microstructure during the final heat treatment. …”
Get full text

A rare case of double pituitary prolactinomas: the diagnostic application of intraoperative ultrasonography and DNA methylation markers by Jared C. Reese, Thomas M. Zervos, Jack Rock, Abeer Tabbarah, Houtan Noushmehr, Grayson Herrgott, Ana Valeria Castro

“…During the 12-month follow-up, methylation profiling and prolactin blood assessments showed that methylation markers clustered with NT specimens, which coincided with prolactinemia normalization, indicating successful tumor control after surgery. …”
Get full text

Risk Factors Associated with Leishmaniasis in the Most Affected Provinces by Leishmania infantum in Morocco by Maryam Hakkour, Asmae Hmamouch, Mohamed Mahmoud El Alem, Abdelhakim Bouyahya, Abdelaali Balahbib, Abdelhak EL Khazraji, Hajiba Fellah, Abderrahim Sadak, Faiza Sebti

“…Regarding the environmental factors, the humidity and the altitude were significant for both CL and VL (P<0.05), while the temperature and the normalized difference vegetation index (NDVI) showed a significance only for VL. …”
Get full text

Do all matches require the same effort? Influence of contextual factors on physical demands during official female handball competitions by Carlos García-Sánchez, Rafael Manuel Navarro, Daniel Mon-López, Raúl Nieto-Acevedo, Enrique Cañadas-García, Alfonso de la Rubia

“…Total distance covered (TDC), high-speed running distance (HSR), high-intensity breaking distance (HIBD), accelerations (ACC), decelerations (DEC) and PlayerLoad (PL) were collected in absolute and relative values (normalized by playing time) using a local positioning system (WIMU PRO, Realtrack Systems S.L., Almería, Spain). …”
Get full text

A Lightweight YOLO Model for Rice Panicle Detection in Fields Based on UAV Aerial Images by Zixuan Song, Songtao Ban, Dong Hu, Mengyuan Xu, Tao Yuan, Xiuguo Zheng, Huifeng Sun, Sheng Zhou, Minglu Tian, Linyi Li

“…Additionally, we integrate a Normalization-based Attention Module (NAM) and introduce a Minimum Point Distance-based IoU (MPDIoU) loss function to further improve the detection capability. …”
Get full text

The Result of Timely Therapy for Whipple's Disease: a Clinical Case by S. N. Mekhtiev, O. A. Mekhtieva, E. Yu. Kalinina, V. E. Karev, A. V. Vanyan, O. M. Berko

“…Treatment with intravenous injections of ceftriaxone 2 g per day for 14 days and trimethoprim/sulfamethoxazole 1920 mg per day for 8 months led to improved health, normalization of laboratory parameters, endoscopic and morphological findings. …”
Get full text

Academic Philosophy as a Way of Life by Eli Kramer, Marta Faustino, Hélder Telo

“…Philosophy is a conversion, a transformation of one’s way of being and living, and a quest for wisdom.” This normative and pedagogic component is a crucial aspect of Hadot’s account of PWL. …”
Get full text

Exploring nonlinear and interaction effects of urban campus built environments on exercise walking using crowdsourced data by Bo Lu, Bo Lu, Qingyun Liu, Hao Liu, Tianxiang Long, Tianxiang Long

“…By applying the XGBoost algorithm and SHAP (SHapley Additive exPlanations), an explainable machine learning framework was established to evaluate the importance of various factors, explore the nonlinear relationships between variables and walking activity, and analyze the interaction effects among these variables.ResultsThe findings underscore the significant impact of several key factors, including the proportion of sports land, proximity to water bodies, and Normalized Difference Vegetation Index NDVI, alongside the notable influence of six distinct campus area types. …”
Get full text

Investigation of calonysterone and 20-hydroxyecdysone effects in high-fat, high-sugar diet-induced obesity rat model by Alaa AM. Osman, Dávid Laczkó, Máté Vágvölgyi, Adrienn Seres-Bokor, Anita Sztojkov-Ivanov, Kata Kira Kemény, Attila Hunyadi, Eszter Ducza

“…Total antioxidant capacity was assessed using a colorimetric assay kit, and global DNA methylation was also measured.CAL entirely prevented HFHSD-induced obesity and decreased the inflammatory cytokine (IL6) level and antioxidant activity in our model. Both 20E and CAL normalized the changed plasma concentration of adiponectin and leptin after the HFHS diet. …”
Get full text

Soil-Rock Slope Stability Analysis under Top Loading considering the Nonuniformity of Rocks by Huang Xian-Wen, Zhi-Shu Yao, Wang Bing-Hui, Zhou Ai-Zhao, Peng-Ming Jiang

“…Based on the developed rock contour establishing algorithm, ten groups (twelve models per group) were established and calculated by finite element method (FEM). After this, normalized ultimate loading increasing multiple N, which was the ultimate loading ratio of rock-containing slope to uniform soil slope, was introduced to evaluate the influence of rock distributions on slope stability. …”
Get full text

Changes in body composition (muscle mass and adipose tissue) among adolescents aged 11–15 from Kraków during the COVID-19 pandemic by Paulina Artymiak, Magdalena Żegleń, Łukasz Kryst

“…The collected data were used to calculate the Corrected Arm Muscle Area (CAMA). The normality of the distribution of each feature was assessed using the Shapiro-Wilk test. …”
Get full text

Desenvolvimento de um aplicativo para dispositivos móveis aplicado a segurança de processos seguindo o modelo de análise preliminar de perigos (APP) by Gabriel de Paiva Bina, Gustavo Henrique Ribeiro de Almeida, Matheus de Souza, Rafael Nicolino de Pietro, Maristhela Passoni de Araújo Marin, Ivan Carlos Franco

“… A produção de amônia tem grande relevância entre os processos químicos, sendo utilizada como base para fertilizantes e por possuir as principais características desejáveis para um fluido refrigerante, como por exemplo: estabilidade química, não ser combustível, não se decompor com facilidade e não ser explosivo nas condições normais de temperatura e pressão. Apesar de não ter riscos altos em sua utilização, a forma de obtenção da amônia traz grandes riscos devido à alta pressão e temperatura exigida pelo processo. …”
Get full text

Anaerobic Soccer Training Model: Enhancing Soccer Players’ Performance through a Combination of Repeated Sprints and 4 vs 4 Games by I Dewa Made Aryananda Wijaya Kusuma, Nining Widyah Kusnanik, Bayu Agung Pramono, Adi Pranoto, Yanyong Phanpheng, Indra Himawan Susanto, Dewa Ayu Praba Amustikarani, Waristra Tyo Nirwansyah, Muhammad Bagus Firzam Bharlaman

“…The Aiken’s V test was used to analyze the assessment data from three expert judgments, followed by percentage analysis for content validity. The normality test was conducted using the Shapiro-Wilk test, while the mean difference was analyzed using the paired sample t-test. …”
Get full text

SViG: A Similarity-Thresholded Approach for Vision Graph Neural Networks by Ismael Elsharkawi, Hossam Sharara, Ahmed Rafea

“…Rather than the number of neighbors, we allow for the specification of the normalized similarity threshold as an input parameter for each layer, which is more intuitive. …”
Get full text

Anticoagulant Utilization and Cost Analysis among Cardiology Inpatients in a Tertiary Care Teaching Hospital of Western Nepal by Sabina Sankhi, Nirmal Raj Marasine, Parbati Thapa, Nim Bahadur Dangi

“…The performance of monitoring parameters such as international normalized ratio (INR), prothrombin time (PT), activated partial thromboplastin time (aPTT), and renal function test were consistent with the American College of Chest Physician (ACCP) guidelines. …”
Get full text

Identification and Quality Evaluation of Raw and Processed Asarum Species Using Microscopy, DNA Barcoding, and Gas Chromatography-Mass Spectrometry by Guangzhe Yao, Wenjuan Ma, Xuhua Huang, Qi Jia, Jiayuan Shen, Yanxu Chang, Huizi Ouyang, Jun He

“…Therefore, Asarum is normally processed to reduce such toxicity and adverse effects. …”
Get full text

Revealing speckle obscured living human retinal cells with artificial intelligence assisted adaptive optics optical coherence tomography by Vineeta Das, Furu Zhang, Andrew J. Bower, Joanne Li, Tao Liu, Nancy Aguilera, Bruno Alvisio, Zhuolin Liu, Daniel X. Hammer, Johnny Tam

“…RPE cell spacing measured across a large set of AI recovered images from 3 participants were in agreement with expected normative ranges. Conclusions The results demonstrate the potential of AI assisted imaging in overcoming a key limitation of RPE imaging and making it more accessible in a routine clinical setting.…”
Get full text

Individualized resting-state functional connectivity abnormalities unveil two major depressive disorder subtypes with contrasting abnormal patterns of abnormality by Keke Fang, Lianjie Niu, Baohong Wen, Liang Liu, Ya Tian, Huiting Yang, Ying Hou, Shaoqiang Han, Xianfu Sun, Wenzhou Zhang

“…Subject-level extreme functional connections, determined by comparing against normative ranges derived from healthy controls using tolerance intervals, were used to identify biological subtypes of MDD. …”
Get full text

Effects of dietary supplementation with fish-derived Bacillus amyloliquefaciens AV5 on growth status, immune response, microbiota, and intestinal health of Nile tilapia (Oreochromi... by Vicent Michael Shija, Huapu Chen, Yi Li, Lishuko Ng’onga, Kwaku Amoah, Zhong Yong, Junxi Chen, Yu Dapeng, Robert Mkuye, Jia Cai

“…In G2, the fish livers changed from abnormally shaped to normally shaped nuclei and the gaps within the liver tissues decreased. …”
Get full text