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1921
Peran Guru Bimbingan dan Konseling Terhadap Kreativitas Anak Berbakat
Published 2019-07-01“…Bimbingan dan konseling adalah layanan yang di berikan kepada individu agar proses pendidikan siswa di sekolah tetap berjalan dengan baik dan lancar. Guru bimbingan dan konseling di sekolah memiliki kedudukan yang penting dalam proses belajar dan mengajar di karenakan guru bimbingan dan konseling tidak hanya mengentaskan siswa yang bermasalah akan tetapi yang tidak bermasalah juga. …”
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1922
HPV-Based Screening, Triage, Treatment, and Followup Strategies in the Management of Cervical Intraepithelial Neoplasia
Published 2013-01-01“…It is known that during the development of cervical cancer associated with HPV infection, a cascade of abnormal events is induced, including disruption of cellular cycle control, alteration of gene expression, and deregulation of microRNA expression. …”
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1923
Periostin as a Biomarker of the Amniotic Membrane
Published 2012-01-01“…We postulated that bone morphogenetic protein (BMP) target genes are putative amniotic membrane markers mainly because deficiency in one of several components of the BMP signaling cascade in mice has been documented to result in defective development of the early amnion. …”
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1924
Improvement of Chronic Rhinosinusitis and Reduction of the Myeloperoxidase-Antineutrophil Cytoplasmic Antibody Titer in a Patient with Eosinophilic Granulomatosis with Polyangiitis...
Published 2021-01-01“…The clinical course of mepolizumab treatment in this patient suggests that the IL5-dependent inflammatory cascade is one of the factors contributing to the increase in MPO-ANCA in EGPA.…”
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1925
Research on Multiobjective Optimization of Bulb Tubular Turbine Based on Orthogonal Test
Published 2021-01-01“…The results show that the optimal design scheme can be obtained when the number of guide vane is 16, the distance between the guide vane and the blade is 1995 mm, the hub ratio is 0.31, the relative twist angle of the blade is 27°, and the cascade density is 0.72. After optimization, the bulb tubular turbine’s efficiency and output are increased by 5.72% and 2.86% at a low flow rate, respectively. …”
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1926
The role of Box A of HMGB1 in producing γH2AX associated DNA breaks in lung cancer
Published 2025-01-01“…We transfected Box A plasmid into lung cancer cell lines to overexpress Box A and evaluated the expression levels of γH2AX foci and other DNA damage response (DDR) signaling cascade markers, including ATM, ATR, and p53. Then, we demonstrated the downstream effects of DSBs on lung cancer, lowering cell proliferation, decreasing cell migration, and promoting apoptosis. …”
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1927
SDF-1/CXCR4 Signaling Maintains Stemness Signature in Mouse Neural Stem/Progenitor Cells
Published 2017-01-01“…Moreover, Notch and RE1 silencing transcription factor (REST) both play an essential role in NSCs/NPCs maintenance and neuronal differentiation and were dramatically downregulated following SDF-1/CXCR4 cascade inhibition. Finally, we demonstrated that the expression of achaete-scute homolog 1 (Ascl1), a proneural gene, and p27, an antiproliferative gene, were significantly increased after genetic elimination of SDF-1 alleles. …”
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1928
The Expanding Role for Retinoid Signaling in Heart Development
Published 2008-01-01“…Germline and conditional knockout mice have revealed which molecular players in the vitamin A signaling cascade are potentially responsible for regulating specific developmental events, and many of these molecules have been temporally and spatially characterized. …”
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1929
Population-level shape variation and otolith asymmetry in Diplodus annularis
Published 2025-01-01“…Abstract Sound detection in fishes relies on the inner ear and peripheral structures, such as calcareous otoliths, which play a crucial role in perceiving movement, orientation, and balance. …”
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1930
O COLONIALISMO NO CORAÇÃO DA TEORIA CRÍTICA: a justificativa colonial em Karl Marx
Published 2014-03-01“…Nesse contexto, pode-se observar com clareza o processo dialético que caracteriza a teorização social, no qual as ideias tanto refletem quanto informam as relações sociais de seu tempo. Nosso artigo visa lançar luz sobre as relações ambíguas entre a teoria de Karl Marx e o ideário colonialista que embasou uma vasta gama de opressões. …”
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1931
Targeting Fibrosis: From Molecular Mechanisms to Advanced Therapies
Published 2025-01-01“…Persistent abnormal activation of “quiescent” fibroblasts that interact with or do not interact with the immune system via complicated signaling cascades, in which parenchymal cells are also triggered, is identified as the main mechanism involved in the initiation and progression of fibrosis. …”
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1932
Multi-omics architecture of childhood obesity and metabolic dysfunction uncovers biological pathways and prenatal determinants
Published 2025-01-01“…This high-risk cluster exhibits a complex interplay across many biological pathways, predominantly underscored by inflammation-related cascades. Further, by incorporating comprehensive information from the environmental risk-scape of the critical pregnancy period, we identify pre-pregnancy body mass index and environmental pollutants like perfluorooctanoate and mercury as important determinants of the high-risk cluster. …”
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1933
A New Image Restoration Method for MUSER
Published 2019-01-01“…Some image restoration methods were applied and obtained good results on Nancay radioheliograph images and Nobeyama radioheliograph images, and some new methods were introduced into processing these complicated solar radio images in recent years. …”
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1934
Innovations in hypoxic training
Published 2025-01-01“…A first symposium on sport at moderate altitude was held in 1965 in Magglingen before a Swiss delegation headed by Dr. Kaspar Wolf sojourned in Mexico in November 1966 to explore the strong discrepancies in the athletes’ individual responses to altitude during their prolonged stay at 2300 m. 60 years later in Magglingen, the knowledge around physiological mechanisms underpinning responses to exercise and training in various low (or high) oxygen environments has increased tremendously with a wide range of recommendations available for altitude training camps or the use of hyperoxia to stimulate specific adaptations. …”
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1935
The Correlation between Chronic Periodontitis and Oral Cancer
Published 2013-01-01“…We conclude that the activation of different inflammatory cascades by chronic periodontitis negatively affects mucosa and bone. …”
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1936
Niqivut (our food)—dimensions of Inuit country food harvesting and significance in Arctic Canada: bountiful, seasonal, “soul food”
Published 2025-01-01“…Climatic and nonclimatic drivers affect Inuit access to these items and have cascading effects on social determinants of Inuit health. …”
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1937
Theoretical Investigation of Terahertz Spoof Surface-Plasmon-Polariton Devices Based on Ring Resonators
Published 2025-01-01“…The band-stop filters based on the cascaded ring resonator exhibit a 0.005 THz broader frequency bandwidth compared to the single-ring resonator filter and achieve a minimum stopband attenuation of 28 dB. …”
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1938
Immunology and Oxidative Stress in Multiple Sclerosis: Clinical and Basic Approach
Published 2013-01-01“…Pro-inflammatory cytokines amplify the inflammatory cascade by compromising the BBB, recruiting immune cells from the periphery, and activating resident microglia. inflammation-associated oxidative burst in activated microglia and macrophages plays an important role in the demyelination and free radical-mediated tissue injury in the pathogenesis of MS. …”
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1939
An Overview of Pathogen Recognition Receptors for Innate Immunity in Dental Pulp
Published 2015-01-01“…PRRs differ in the signaling cascades and host responses activated by their engagement and in their tissue distribution. …”
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1940
Evidence for the Involvement of Lipid Rafts and Plasma Membrane Sphingolipid Hydrolases in Pseudomonas aeruginosa Infection of Cystic Fibrosis Bronchial Epithelial Cells
Published 2017-01-01“…This reorganization of cell membrane may be responsible for activation of a signaling cascade, culminating in aberrant inflammatory response in CF bronchial epithelial cells upon bacterial infection. …”
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