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1881
Blood coagulation dynamics: mathematicalmodeling and stability results
Published 2011-03-01“…Coagulation is initiated in response to endothelial surface vascular injury or certain biochemical stimuli, by the exposure of plasma to Tissue Factor (TF), that activates platelets and the coagulation cascade, inducing clot formation, growth and lysis.In recent years considerable advances have contributed to understand this highly complex process and some mathematical and numerical models have been developed. …”
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1882
Desromantizando a História da Escravidão nos Estados Unidos: O modo trágico em Scenes of Subjection de Saidiya Hartman
Published 2025-01-01“…RESUMO O presente artigo parte de Scenes of Subjection, primeiro livro publicado pela historiadora afro-americana Saidiya Hartman, para refletir sobre as formas de narrar o passado da escravidão. Em um primeiro momento, faço um breve apanhado sobre a historiografia da escravidão nos Estados Unidos e situo o lugar ocupado pela pesquisadora nesse cenário. …”
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1883
Levetiracetam Ameliorates L-DOPA-Induced Dyskinesia in Hemiparkinsonian Rats Inducing Critical Molecular Changes in the Striatum
Published 2015-01-01“…These data support that levetiracetam acts at multiple sites in the pathogenetic cascade of LID, and that further understanding of these actions of antiepileptics may contribute to developing new LID therapies.…”
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1884
Enantioselective Heck/Tsuji−Trost reaction of flexible vinylic halides with 1,3-dienes
Published 2025-01-01“…Despite significant progress in relative rigid skeleton substrates, the implementation of asymmetric Heck/cross-coupling cascades of highly flexible haloalkene substrates remains a challenging and and long-standing goal. …”
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1885
Las formas del juvenicidio en México
Published 2022-01-01“…Se presentan los resultados de una investigación cualitativa y descriptiva sobre las formas en que se desarrolla el juvenicidio en México, considerando que puede presentarse como masacre o de manera sutil y rutinaria. El trabajo implicó el análisis de noticias de eluniversal. com.mx y lajornada.com.mx donde los jóvenes aparecen como actores centrales, publicadas del 1 de septiembre al 30 de noviembre de 2020. …”
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1886
The Rise of Pluripotent Stem Cell-Derived Glia Models of Neuroinflammation
Published 2025-01-01“…This review systematically discusses the role of human pluripotent stem cell (hPSC)-derived glia and supporting cells within the CNS, including astrocytes, microglia, oligodendrocyte precursor cells, pericytes, and endothelial cells, to describe the state of the field and hope for future discoveries. hPSC-derived cells offer an expanded potential to study the pathobiology of neuroinflammation and immunomodulatory cascades that impact disease progression. While much progress has been made in the development of models, there is much left to explore in the application of these models to understand the complex inflammatory response in the CNS.…”
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1887
Sequential harmonic spin–orbit angular momentum generation in nonlinear optical crystals
Published 2024-12-01“…Alternatively, a simple uniaxial crystal can be used to simultaneously generate four OAM states of light through the second harmonic generation and cascaded optical spin–orbit interaction (SOI) processes. …”
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1888
PAI-1: An Integrator of Cell Signaling and Migration
Published 2011-01-01“…These events appear distinct from the original function of uPA/PAI-1 as modulators of the plasmin-based proteolytic cascade. The multifaceted interactions of PAI-1 with specific matrix components (i.e., vitronectin), the low-density lipoprotein receptor-related protein-1 (LRP1), and the uPA/uPA receptor complex have dramatic consequences on the migratory phenotype and may underlie the pathophysiologic sequalae of PAI-1 deficiency and overexpression. …”
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1889
The MAPK MEK1/2-ERK1/2 Pathway and Its Implication in Hepatocyte Cell Cycle Control
Published 2012-01-01“…Many reports suggest that the mitogen-activated protein kinase (MAPK) ERK1/2 can support hepatocyte proliferation in vitro and in vivo and the MEK/ERK cascade acts as an essential element in hepatocyte responses induced by the EGF. …”
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1890
Nutrition in patients with traumatic brain injury: Nutrition in patients with TBI
Published 2024-01-01“…After the initial injury, a cascade of events at the cellular and molecular level, including cell swelling, changes in cell membrane permeability, influx of immune or inflammatory mediators, and release of excitatory neurotransmitters result in so-called "secondary" brain damage. …”
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1891
Origen y desarrollo del atípico poblado de San José de Suaita (1907-1980)
Published 2009-01-01“…Lo que se quiere narrar en este artículoes cómo nace, durante la primera mitad del siglo XX, un asentamiento humano decaracterísticas muy originales a la sombra de la hacienda-fábrica de San José de Suaita.…”
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1892
Emphasizing the Early Phases of the Software Development Process Before Deploying Smart Contracts
Published 2025-01-01“…The case is analyzed from three different perspectives: 1) Economic, finding that re-deploying smart contracts does not implicate considerable cost; 2) Computational perspective, finding that it generates various implications: smart contract purpose duplication, storage wastage, failure to recognize the original smart contract, cascade dependency repercussion, and migration problems; and 3) Interconnected effect, a simple change, required for upgrading smart contracts, generates broad collateral repercussions in both on-chain (within the blockchain) and off-chain.…”
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1893
Fuzzy Constrained Predictive Optimal Control of High Speed Train with Actuator Dynamics
Published 2016-01-01“…The dynamics feature of the high speed train is modeled as a cascade of cars connected by flexible couplers, and the formulation is mathematically transformed into a Takagi-Sugeno (T-S) fuzzy model. …”
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1894
Analysis and Prediction of the Interval Duration between the First and Second Accidents considering the Spatiotemporal Threshold
Published 2022-01-01“…First, the spatiotemporal definition method is applied to identify the cascaded first accident and the second accident. Then, on the basis of using Kaiser-Meyer-Olkin (KMO) measure and Bartlett’s sphere test statistics to ensure the applicability of the data to the factor analysis method, the explanatory variables that can significantly affect the interval duration are obtained through the factor analysis method. …”
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1895
Bifurcation Scenarios of Neural Firing Patterns across Two Separated Chaotic Regions as Indicated by Theoretical and Biological Experimental Models
Published 2013-01-01“…After period-2 bursting, the chaotic firings lay in a period-adding bifurcation scenario or in a period-doubling bifurcation cascade. The deterministic dynamics of the chaotic firing patterns were identified using a nonlinear prediction method. …”
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1896
Design of High-Voltage Switch-Mode Power Amplifier Based on Digital-Controlled Hybrid Multilevel Converter
Published 2016-01-01“…Under the control of input signal, cascaded power converters with separate DC sources operate in PSM switch mode to directly generate high-voltage and high-power output. …”
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1897
A Data-Driven Method for Supporting Self-Adapt Large-Scale Group Decision-Making: A Case Study on Resilient Design of Firm’s Product
Published 2024-01-01“…Third, a novel approach called analysis target cascading (ATC) has been suggested to address the limitations of traditional weighing methods used in previous LSGDM studies. …”
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1898
Bifurcation Analysis and Chaos Control in a Discrete Epidemic System
Published 2015-01-01“…Meanwhile, there appears the cascade of period-doubling 2, 4, 8 bifurcation and chaos sets from the fixed point. …”
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1899
A Sliding Mode LCO Regulation Strategy for Dual-Parallel Underactuated UAV Systems Using Synthetic Jet Actuators
Published 2015-01-01“…Since dual-parallel underactuated systems cannot be expressed in a strict feedback or cascade form, standard backstepping-based control techniques cannot be applied. …”
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1900