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  1. 1721

    The association between oral microbiome and gastric precancerous lesions by Yifei Chen, Lei Lei, Mengying Xia, Ran Cheng, He Cai, Tao Hu

    Published 2025-01-01
    “…ABSTRACT Gastric precancerous lesions are thought to be precursors in the occurrence and development of gastric cancer through Correa's cascade. Recent studies have investigated the association between the oral microbiome and gastric precancerous lesions. …”
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    Article
  2. 1722

    Cross-Talk between PPARγ and Insulin Signaling and Modulation of Insulin Sensitivity by Anna Leonardini, Luigi Laviola, Sebastio Perrini, Annalisa Natalicchio, Francesco Giorgino

    Published 2009-01-01
    “…PPARγ activation in mature adipocytes induces the expression of a number of genes involved in the insulin signaling cascade, thereby improving insulin sensitivity. PPARγ is the master regulator of adipogenesis, thereby stimulating the production of small insulin-sensitive adipocytes. …”
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  3. 1723

    Mitochondrial DNA leakage: underlying mechanisms and therapeutic implications in neurological disorders by Guangming Zhang, Huayuan Wei, Anliu Zhao, Xu Yan, Xiaolu Zhang, Jiali Gan, Maojuan Guo, Jie Wang, Fayan Zhang, Yifang Jiang, Xinxing Liu, Zhen Yang, Xijuan Jiang

    Published 2025-02-01
    “…The escaped mtDNA activates cytosolic DNA sensors, especially cyclic gmp-amp synthase (cGAS) signalling and inflammasome, initiating neuroinflammatory cascades via pathways, exacerbating a spectrum of neurological pathologies. …”
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    Article
  4. 1724

    Complement Inhibition as a Proposed Neuroprotective Strategy following Cardiac Arrest by Brad E. Zacharia, Zachary L. Hickman, Bartosz T. Grobelny, Peter A. DeRosa, Andrew F. Ducruet, E. Sander Connolly

    Published 2009-01-01
    “…Emerging preclinical as well as recent human clinical evidence suggests that activation of the complement cascade plays a critical role in the pathogenesis of GCI/R injury following OHCA. …”
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    Article
  5. 1725

    Role of RING-Type E3 Ubiquitin Ligases in Inflammatory Signalling and Inflammatory Bowel Disease by Liguo Zhu, Ying Li, Longyuan Zhou, Guang Yang, Ying Wang, Jing Han, Li Li, Shenghong Zhang

    Published 2020-01-01
    “…Ubiquitination is a three-step enzymatic cascade for posttranslational protein modification. …”
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    Article
  6. 1726

    Topological bound states in the continuum in a non-Hermitian photonic system by Luo Yihao, Sun Xiankai

    Published 2025-01-01
    “…Here, we investigated non-Hermitian photonics based on a parallel cascaded-resonator system, where both direct and indirect coupling between adjacent resonators can be independently manipulated. …”
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  7. 1727

    Metallothioneins in Inflammatory Bowel Diseases: Importance in Pathogenesis and Potential Therapy Target by Anna Socha-Banasiak, Patrycja Sputa-Grzegrzółka, Jędrzej Grzegrzółka, Krzysztof Pacześ, Piotr Dzięgiel, Beata Sordyl, Hanna Romanowicz, Elżbieta Czkwianianc

    Published 2021-01-01
    “…In the treatment of patients with Crohn’s disease (CD) and ulcerative colitis (UC), it is increasingly common to use biological drugs that selectively affect individual components of the inflammatory cascade. However, administering the medicines currently available does not always result in obtaining and maintaining remission, and it may also lead to the development of resistance to a given agent over time. …”
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    Article
  8. 1728

    A structural model of the VEGF signalling pathway: Emergence of robustness and redundancy properties by Floriane Lignet, Vincent Calvez, Emmanuel Grenier, Benjamin Ribba

    Published 2012-11-01
    “…If further calibrated and validated, this model could serve as tool to analyse and formulate new hypothesis on th e VEGF signalling cascade and its role in cancer development and treatment.…”
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    Article
  9. 1729

    Risk Factors for Asthma in a Helminth Endemic Area in Bahia, Brazil by Luciana S. Cardoso, Daniela M. Costa, Maria Cecília F. Almeida, Robson P. Souza, Edgar M. Carvalho, Maria Ilma Araujo, Ricardo R. Oliveira

    Published 2012-01-01
    “…Prevalence of Schistosoma mansoni infection was 57.4% and Ascaris lumbricoides, 30.8%. Asthma was found in 13.1% of the population, and 35.1% of them had a positive SPT. …”
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    Article
  10. 1730

    Políticas de reconhecimento e sofrimento psíquico em tempos neoliberais by Jainara Gomes de Oliveira

    Published 2024-12-01
    “…No contexto desse discurso, emergem determinadas prescrições relativas às maneiras específicas como os sujeitos devem narrar e reconhecer certas modalidades de sofrimento. …”
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    Article
  11. 1731

    Angiogenesis in Spontaneous Tumors and Implications for Comparative Tumor Biology by C. Benazzi, A. Al-Dissi, C. H. Chau, W. D. Figg, G. Sarli, J. T. de Oliveira, F. Gärtner

    Published 2014-01-01
    “…The complex relationships between the angiogenic signaling cascade and antiangiogenic substances have indicated the angiogenic pathway as a valid target for anticancer drug development and VEGF has become the primary antiangiogenic drug target. …”
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  12. 1732

    Automated Particle Shape Identification and Quantification for DEM Simulation of Rockfill Materials in Subgrade Construction by Hao Bai, Xiangyu Hu, Ruidong Li, Fei Chen, Zhiyong Liao

    Published 2022-01-01
    “…This study first identifies the subgrade rockfill particle contour by machine learning algorithms, including AdaBoost, Cascade, and sliding windows. Then, the shape evaluation indexes of length flatness, edge angle, and roughness are quantified, and the statistical analysis of each index is presented. …”
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  13. 1733

    Travessias da digitalização: da internet à inteligência artificial by Lucia Santaella

    Published 2023-10-01
    “…Diante disso, o objetivo deste artigo é seguir o histórico de desenvolvimento da era da internet de modo a marcar os passos decisivos que foram gradativamente mergulhando as sociedades em contradições e ambivalências. …”
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  14. 1734

    Comprehensive guide for epigenetics and transcriptomics data quality control by Arianna Comendul, Frederique Ruf-Zamojski, Colby T. Ford, Pankaj Agarwal, Elena Zaslavsky, German Nudelman, Manoj Hariharan, Aliza Rubenstein, Hanna Pincas, Venugopalan D. Nair, Adam M. Michaleas, Philip D. Fremont-Smith, Darrell O. Ricke, Stuart C. Sealfon, Christopher W. Woods, Kajal T. Claypool, Rafael Jaimes, III

    Published 2025-03-01
    “…The interrogation of the epigenome and transcriptome cascade requires analyzing disparate datasets from multiple assay types, often at single-cell resolution, derived from the same biospecimen. …”
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  15. 1735

    Tilted-Mode All-Optical Diffractive Deep Neural Networks by Mingzhu Song, Xuhui Zhuang, Lu Rong, Junsheng Wang

    Published 2024-12-01
    “…Diffractive deep neural networks (D<sup>2</sup>NNs) typically adopt a densely cascaded arrangement of diffractive masks, leading to multiple reflections of diffracted light between adjacent masks, thereby affecting the network’s inference capability. …”
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  16. 1736

    A Staged Finite-Time Control Strategy for Formation of Underactuated Unmanned Surface Vehicles by Hui Ye, Xiaofei Yang, Chunxiao Ge, Zhaoping Du

    Published 2021-01-01
    “…To deal with the nonholonomic behavior of the system, the dynamics of the USV is transformed into cascade systems. Then, the finite-time controller is designed for each vehicle based on homogeneity theory. …”
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  17. 1737

    Histórias por um fio: narração mediada em tempo real by Daniela Côrtes Maduro

    Published 2016-01-01
    “…El presente articulo pretende ser un a reflexió n sobre la influ e ncia d el medio en la transmissió n de una história, tornando evidente el enlace entre diversas formas de narrar, desde la trad ic ión oral hasta el uso de sensores.…”
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  18. 1738

    A Simple Cable Radiated Emission Evaluation Method for Table-Top Setups According to CISPR 11 and CISPR 32 by Xinglong Wu, Alessandro Grande, Xiaokang Liu, Flavia Grassi, Giordano Spadacini, Sergio A. Pignari, Fabio Vallarino, Luca Ghezzi

    Published 2025-01-01
    “…By noting the fact that table-top test setup usually involves long interconnecting cable bundle that radiates significantly, the work proposes a fast and simple pre-compliance radiated emission evaluation method based on cascaded Hertzian dipoles and its radiation theory. …”
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  19. 1739

    Inflammatory Mechanisms of Organ Crosstalk during Ischemic Acute Kidney Injury by Laura E. White, Heitham T. Hassoun

    Published 2012-01-01
    “…Kidney ischemia-reperfusion injury (IRI) incites a proinflammatory cascade and releases cellular and soluble mediators with systemic implications for remote organ injury. …”
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    Article
  20. 1740

    Common Errors in Digital Panoramic Radiographs of Patients with Mixed Dentition and Patients with Permanent Dentition by Benjamin Peretz, Maya Gotler, Israel Kaffe

    Published 2012-01-01
    “…Properly positioning the patient is the most important factor in preventing a cascade of errors.…”
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