The EGF Receptor and HER2 Participate in TNF-α-Dependent MAPK Activation and IL-8 Secretion in Intestinal Epithelial Cells by Humberto B. Jijon, Andre Buret, Christina L. Hirota, Morley D. Hollenberg, Paul L. Beck

“…TNF-α activates multiple mitogen-activated protein kinase (MAPK) cascades in intestinal epithelial cells (IECs) leading to the secretion of interleukin 8 (IL-8), a neutrophil chemoattractant and an angiogenic factor with tumor promoting properties. …”
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Nasal hyperreactivity and inflammation in allergic rhinitis by I. M. Garrelds, C. de Graaf-in't Veld, R. Gerth van Wijk, F. J. Zijlstra

“…The histopathological features of allergic inflammation involve an increase in blood flow and vascular permeability, leading to plasma exudation and the formation of oedema. In addition, a cascade of events occurs which involves a variety of inflammatory cells. …”
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A Rare Case of Post-Partum Hemorrhage with Refractory Thrombotic Microangiopathy, and Hepatic Infarction: A Diagnostic Dilemma with High Mortality by Naved Yousuf Hasan, Asiah Salem Rugaan, Noha Ahmed Mohamed Ali, Masood Iqbal

“…It is highly imperative to be aware of the complications of postpartum hemorrhage, as it should be treated promptly to minimize the possible cascade of multi-organ failure with high maternal and fetal mortality. …”
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Epigenetic regulation of the inflammatory response in stroke by Jingyi Liang, Fei Yang, Zixiao Li, Qian Li

“…Suppressing the inflammatory response has been shown to mitigate this cascade of events in experimental stroke models. However, in clinical trials of anti-inflammatory agents, long-term immunosuppression has not demonstrated significant clinical benefits for patients. …”
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An Emerging Role for IQGAP1 in Regulating Protein Traffic by Mahasin Osman

“…Recent evidence suggests that IQGAP1 plays its role in cell growth through regulating the conserved mTOR pathway. The mTOR signaling cascade has been implicated in membrane traffic and is activated in nearly all human cancers, but clinical response to the mTOR-specific inhibitor rapamycin has been disappointing. …”
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Non-Isolated Power Factor Corrected AC/DC Converter with High Step-Down Voltage Ratio for Low-Power Applications by Lalitha T. S. Annambhotla, P. Parthiban

“…In addition, the number of conducting devices during the current path is also the same as the conventional buck converter due to cascading and hence offers lower conduction losses. …”
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The Highly Sensitive Child as a challenge for education – introduction to the concept by Monika Baryła-Matejczuk, Małgorzata Artymiak, Rosario Ferrer-Cascales, Moises Betancort

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The community as an active part in the implementation of interventions for the prevention and care of tuberculosis: A scoping review. by Lesly Chavez-Rimache, César Ugarte-Gil, Maria J Brunette

“…Community participation not only strengthens the capacities of health systems for the prevention and care of tuberculosis, but also allows a better understanding of the disease from the perspective of the patient and the affected community by identifying barriers and difficulties through of the tuberculosis care cascade. Engaging key community stakeholders in co-creating solutions offers a critical pathway for local governments to eradicate TB.…”
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Flow optimization in vascular networks by Radu C. Cascaval, Ciro D'Apice, Maria Pia D'Arienzo, Rosanna Manzo

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A data-driven group retrosynthesis planning model inspired by neurosymbolic programming by Xuefeng Zhang, Haowei Lin, Muhan Zhang, Yuan Zhou, Jianzhu Ma

“…Inspired by human learning, our algorithm, akin to neurosymbolic programming, builds upon commonly used multi-step concepts such as cascade and complementary reactions and can evolve from practical experiences, enhancing the prediction model for fundamental and compositional reaction templates. …”
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Stepping Into an Equatorial Plasma Bubble With a Swarm Overfly by L. Spogli, L. Alfonsi, C. Cesaroni

“…By exploiting the use of ground‐based receivers of Global Navigation Satellite System (GNSS) signals in combination with the Swarm plasma density measurements, we study the irregularities in the EPB formed at ∼60°W and investigate the different scales of the irregularities and the cascading processes along the magnetic flux tubes. …”
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Early Stroke Prediction Methods for Prevention of Strokes by Mandeep Kaur, Sachin R. Sakhare, Kirti Wanjale, Farzana Akter

“…A noninvasive approach for the early diagnosis of the strokes is proposed. The cascaded prediction algorithms are time-consuming in producing the results and cannot work on the raw data and without making use of the properties of EEG. …”
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Accounting Data Encryption Processing Based on Data Encryption Standard Algorithm by Meixi Chen

“…The 3DES algorithm is a cascade of the DES algorithm, and its encryption process is based on the DES algorithm principle. …”
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Application of BIM Digital Information Technology in the Economic Optimization Operation of Integrated Energy Systems by Jingjing Bu

“…In terms of energy output, the system uses the principle of energy cascade utilization to recover and utilize the waste heat generated by the traditional generator set and then collects it through absorption. …”
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Automatic Voltage Regulator Betterment Based on a New Fuzzy FOPI+FOPD Tuned by TLBO by Mokhtar Shouran, Mohammed Alenezi

“…The proposed system combines fuzzy control theory with the Fractional Order Proportional Integral Derivative (FOPID) technique and employs cascading control theory to significantly improve reliability and robustness. …”
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A Protective Role of Canonical Wnt/β-Catenin Pathway in Pathogenic Bacteria-Induced Inflammatory Responses by Zhongjia Jiang, Weiping Zhou, Xing Tian, Peng Zou, Ning Li, Chunmeng Zhang, Yanting Li, Guangyan Liu

“…A baseline extent of inflammation is supposed to be tightly associated with a sequence of immune-modulated processes, resulting in the protection of the host organism against pathogen invasion; however, as a matter of fact is that an uncontrolled inflammatory cascade is the main factor responsible for the host damage, accordingly suggesting a significant and indispensable involvement of negative feedback mechanism in modulation of inflammation. …”
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Ethnomedicinal, Pharmacological, and Phytochemical Overview of Diplazium esculentum by Abhishek Singh

“…Mechanistic insights delve into molecular pathways elucidating the interactions of D. esculentum bioactives with cellular targets and signalling cascades. Furthermore pharmacokinetic considerations shed light on the absorption distribution metabolism and excretion ADME profiles of its constituents providing critical insights into their bioavailability and pharmacological efficacy. …”
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Comportamiento de parasitismo intestinal en el área de salud de Potrerillo by Juana Neycy Cazorla Pastor, Mariela Pérez Morales, Sandra Mas, Belquis Marín

“…<br /><strong>Resultados:</strong> de los 286 análisis realizados 52 resultaron positivos, para un frecuencia parasitaria de 18, 1 %; entre los protozoarios predominó la Entamoeba histolytica con 8, 04 % fundamentalmente en adultos (6, 99 %), la Giardia lamblia (5,59 %) con predominio en los niños (3, 49 %), la frecuencia de presentación de los helmintos fue de 4, 53 % y predominó el Áscaris lumbricoides con 4, 19 % entre los infantes (ocho niños) y cuatro adultos 1,39 % y Trichuris trichiura (0, 34 %) en un niño.…”
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Investigating Use of Crushed Glass as Partial Replacement of Sand to Improve Finish Mortar Strength. by Ashaba, Dennis

“…The high calcium oxide content and low magnesium oxide content probably mean that lime was provided from calcareous stones rather than dolomitic.…”
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Soil-Transmitted Helminth Reinfection and Associated Risk Factors among School-Age Children in Chencha District, Southern Ethiopia: A Cross-Sectional Study by Zerihun Zerdo, Tsegaye Yohanes, Befikadu Tariku

“…The estimated prevalence of reinfection (95%CI) for Ascaris lumbricoides, Trichuris trichiura, and hookworms was 23.8% (21.1–28.2), 16.2% (12.7–20.1), and 1.0% (0.3–2.5), respectively. …”
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