FlowMFD: Characterisation and classification of tor traffic using MFD chromatographic features and spatial–temporal modelling by Liukun He, Liangmin Wang, Keyang Cheng, Yifan Xu

“…In addition, FlowMFD utilises a cascaded model with a two‐dimensional convolutional neural network (2D‐CNN) and a bidirectional gated recurrent unit to capture spatial‐temporal dependencies between MFDCF. …”
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Nitrogen enrichment and vascular plant richness loss reduce bryophyte richness by Maeve Lin, Ariel Bergamini, Noémie A. Pichon, Eric Allan, Steffen Boch

“…Our results highlight novel mechanisms by which land-use intensification can affect bryophytes and suggest that a loss of vascular plant richness might have cascading effects on other taxonomic groups.…”
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Battery Energy Storage Systems in Microgrids: A Review of SoC Balancing and Perspectives by Thales Augusto Fagundes, Guilherme Henrique Favaro Fuzato, Lucas Jonys Ribeiro Silva, Augusto Matheus dos Santos Alonso, Juan C. Vasquez, Josep M. Guerrero, Ricardo Quadros Machado

“…Moreover, in this article, we discuss alternatives to improve EMS and strategies regarding the topology of power converters, including redundancy-based topology, modular multilevel converter, cascaded-based converter, and hybrid-type systems. …”
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Long-Term Dynamic Monitoring of Post-Tensioning External Tendons: Temperature Effect Evaluation by Luis Chillitupa-Palomino, Carlos M. C. Renedo, Jaime H. García-Palacios, Iván M. Díaz

“…On this subject, this paper presents the experimental long-term monitoring of several post-tensioning external tendons in a high-speed railway bridge in which a sectorized weighted peak-picking frequency identification procedure is proposed for frequency estimation, alongside a cascade clustering process, which allows meaningful frequency estimates to be selected. …”
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Plasma proteome fingerprint in kidney diseases by Kirill S. Nikolsky, Arthur T. Kopylov, Valeriya I. Nakhod, Natalia V. Potoldykova, Dmitry V. Enikeev, Tatiana V. Butkova, Liudmila I. Kulikova, Kristina A. Malsagova, Vladimir R. Rudnev, Denis V. Petrovskiy, Alexander A. Izotov, Anna L. Kaysheva

“…These proteins are important participants of complement and coagulation cascade activation and lipid metabolism.ResultsThe revealed phosphorylated proteoforms (CFB, C4A/C4B, F2, APOB, TTR, and NRAP) were identified. …”
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USP20 mediates malignant phenotypic changes in bladder cancer through direct interactions with YAP1 by Wensun Chen, Siqi Wu, Yifan Chen, Weijian Li, Yiqing Cao, Yingchun Liang, Xiyu Dai, Xinan Chen, Yilin Chen, Tian Chen, Shenghua Liu, Chen Yang, Haowen Jiang

“…Hippo pathway activity is controlled by the phosphorylation cascade in the MST1/2-LATS1/2-YAP1 axis, in addition to other modifications such as ubiquitination of the Hippo pathway proteins through the co-regulation of E3 ligases and deubiquitinases. …”
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Assessment of Artificial Neural Networks for Hourly Solar Radiation Prediction by Tamer Khatib, Azah Mohamed, K. Sopian, M. Mahmoud

“…The Four ANNs topologies were used including a generalized (GRNN), a feed-forward backpropagation (FFNN), a cascade-forward backpropagation (CFNN), and an Elman backpropagation (ELMNN). …”
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Deep Vein Thrombosis and Pulmonary Embolism Secondary to Thrombophilic Disorder: A Case Report by Satbir Kaur Malik, Vineetha Naga Lakshmi Giduturi, Sindhuri Goud Nimmala, Vijayashree Gokhale

“…The most common inherited thrombophilias—such as Factor V Leiden mutation, prothrombin G20210A mutation and deficiencies in protein C, protein S and antithrombin III—are a group of genetic conditions that predispose individuals to thrombotic events by influencing various factors involved in the coagulation cascade. Deep Vein Thrombosis (DVT) is a common condition that is part of venous thromboembolism disorders and represents the third most common cause of death from cardiovascular disease, following heart attacks and strokes. …”
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Genetic Evidence of Killer Whale Predation on White Sharks in Australia by Isabella M. M. Reeves, Andrew R. Weeks, Alison V. Towner, Rachael Impey, Jessica J. Fish, Zach S. R. Clark, Paul A. Butcher, Lauren Meyer, David M. Donnelly, Charlie Huveneers, Nicky Hudson, Adam D. Miller

“…ABSTRACT Killer whales (Orcinus orca) have been documented to prey on white sharks (Carcharodon carcharias), in some cases causing localised shark displacement and triggering ecological cascades. Notably, a series of such predation events have been reported from South Africa over the last decade, with killer whales specifically targeting sharks' liver. …”
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Codeine 3-O-demethylase catalyzed biotransformation of morphinan alkaloids in Escherichia coli: site directed mutagenesis of terminal residues improves enzyme expression, stability... by Garrick W. K. Spencer, Xu Li, Kenny W. L. Lam, George Mutch, Fiona H. Fry, Sally L. Gras

“…The enzyme codeine 3-O-demethylase can transform morphinan alkaloids by O-demethylation and has been applied in single step biotransformation reactions or as part of larger biosynthetic cascade, however, the productivity for these reactions remains low and suboptimal enzyme properties could be improved. …”
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Research progress on modification of hemodialysis membranes with anticoagulant properties by Xuan WANG, Zehua LI, Runjie SHI, Tiantian LI, Ruolin WANG, Chunmei NIU

“…However, when the membrane material is in contact with blood directly, plasma proteins will quickly adsorb on the surface of the membrane and bind to the glycoprotein receptors on platelets, resulting in platelet activation, coagulation cascade and complement activation. This will inevitably induce coagulation and thrombosis, threatening the health and life safety of patients. …”
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A method of processing mechanical mixtures using vortex set of deep separation by V. I. Kuznetsov, O. A. Sharikov

“…The method involves processing mechanical mixtures using the new physical process of the vortex effect of the confuser, the series cascade connection of technological units in the main processing line and an additional line machines: separator-constrictors, cyclonesconstrictors, overpasses, separators exhaust air that drives the indivisible particles of the mixture of the overpass with the ejector, to reuse the exhaust air. …”
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Procoagulant Phospholipids and Tissue Factor Activity in Cerebrospinal Fluid from Patients with Intracerebral Haemorrhage by Patrick Van Dreden, Guy Hue, Jean-François Dreyfus, Barry Woodhams, Marc Vasse

“…Brain contains large amounts of tissue factor, the major initiator of the coagulation cascade. Neuronal apoptosis after intracerebral haemorrhage (ICH) leads to the shedding of procoagulant phospholipids (PPLs). …”
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Neurokinin-1 Receptor Antagonist Treatment in Polymicrobial Sepsis: Molecular Insights by Akhil Hegde, Yung-Hua Koh, Shabbir M. Moochhala, Madhav Bhatia

“…We conclude that substance P acting via neurokinin-1 receptor in sepsis initiated signaling cascade mediated mainly by protein kinase C-α, led to NF-κB and activator protein-1 activation, and further modulated proinflammatory mediators.…”
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Targeting C-Reactive Protein in Inflammatory Disease by Preventing Conformational Changes by J. R. Thiele, J. Zeller, H. Bannasch, G. B. Stark, K. Peter, S. U. Eisenhardt

“…The chance to prevent the formation of proinflammatory mediators in ubiquitous inflammatory cascades has pushed therapeutic strategies by targeting pCRP dissociation in inflammation. …”
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Pharmacological Inhibition of p38 Mitogen-Activated Protein Kinases Affects KC/CXCL1-Induced Intraluminal Crawling, Transendothelial Migration, and Chemotaxis of Neutrophils In Viv... by Najia Xu, Mokarram Hossain, Lixin Liu

“…Leukocyte recruitment to the site of inflammation is a multistep process governed by specific signalling cascades. After adhesion in the lumen, many leukocytes crawl to optimal sites at endothelial junctions and transmigrate to extravascular tissue in a Mac-1-dependent manner. …”
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Sophocarpine Attenuates LPS-Induced Liver Injury and Improves Survival of Mice through Suppressing Oxidative Stress, Inflammation, and Apoptosis by Zhengyu Jiang, Yan Meng, Lulong Bo, Changli Wang, Jinjun Bian, Xiaoming Deng

“…Mechanistic evidence was also investigated in the present study as sophocarpine inhibited hepatic expression of the CYP2E/Nrf2 pathway during oxidative stress, inactivated p38/JNK cascade and NF-κB pathway, and, meanwhile, suppressed PI3K/AKT signaling that reduced apoptosis. …”
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Post-Translational Modifications of Proteins Orchestrate All Hallmarks of Cancer by Pathea Shawnae Bruno, Aneeta Arshad, Maria-Raluca Gogu, Natalie Waterman, Rylie Flack, Kimberly Dunn, Costel C. Darie, Anca-Narcisa Neagu

“…In this review, we summarized and analyzed a wide spectrum of PTMs of proteins involved in all regulatory mechanisms that drive tumorigenesis, genetic instability, epigenetic reprogramming, all events of the metastatic cascade, cytoskeleton and extracellular matrix (ECM) remodeling, angiogenesis, immune response, tumor-associated microbiome, and metabolism rewiring as the most important hallmarks of cancer. …”
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The Causative Pathogen Determines the Inflammatory Profile in Cerebrospinal Fluid and Outcome in Patients with Bacterial Meningitis by Denis Grandgirard, Rahel Gäumann, Boubacar Coulibaly, Jean-Pierre Dangy, Ali Sie, Thomas Junghanss, Hans Schudel, Gerd Pluschke, Stephen L. Leib

“…The brain’s inflammatory response to the infecting pathogen determines the outcome of bacterial meningitis (BM), for example, the associated mortality and the extent of brain injury. The inflammatory cascade is initiated by the presence of bacteria in the cerebrospinal fluid (CSF) activating resident immune cells and leading to the influx of blood derived leukocytes. …”
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Audio2DiffuGesture: Generating a diverse co-speech gesture based on a diffusion model by Hongze Yao, Yingting Xu, Weitao WU, Huabin He, Wen Ren, Zhiming Cai

“…Specifically, we employed cascaded 1D convolutions to extract features from the audio waveform and a two-stage attention mechanism to capture features from the Mel-spectrogram. …”
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