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2321
Vitamin D Receptor, Retinoid X Receptor, Ki-67, Survivin, and Ezrin Expression in Canine Osteosarcoma
Published 2012-01-01“…Upon activation, vitamin D receptors (VDRs) combine with retinoid receptor (RXR) forming a heterodimer initiating a cascade of events. Vitamin D's antineoplastic activity and its mechanism of action in OS remain to be clearly established. …”
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2322
Thermodynamic and Exergoeconomic Study of an Absorption-Compression Refrigeration Cycle Driven by a Geothermal Energy Resource
Published 2024-10-01“…This article aims to investigate thermodynamic and exergoeconomic analyses of the cascade absorption refrigeration with a vapor compression refrigeration system driven by a geothermal renewable energy source. …”
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2323
The Expanding Family of Bone Marrow Homing Factors for Hematopoietic Stem Cells: Stromal Derived Factor 1 Is Not the Only Player in the Game
Published 2012-01-01“…Moreover, the responsiveness of HSPCs to an SDF-1 gradient is enhanced by some elements of innate immunity (e.g., C3 complement cascade cleavage fragments and antimicrobial cationic peptides, such as cathelicidin/LL-37 or β2-defensin) as well as prostaglandin E2 (PGE2). …”
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2324
Determinantes da Rotatividade das Carteiras dos Fundos de Investimento em Ações
Published 2015-01-01“…Usando a metodologia de Gaspar, Massa e Matos (2005), este estudo evidencia as características dos fundos e dos gestores impactando o nível de rotatividade das carteiras dos fundos. …”
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2325
Targeting ferroptosis in prostate cancer management: molecular mechanisms, multidisciplinary strategies and translational perspectives
Published 2025-02-01“…Ferroptosis is a new form of regulatory cell death caused by iron-dependent lipid peroxidation, which has a dual role in PCa evolution and treatment due to the multi-omics cascade of interactions among pathways and environmental stimuli. …”
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2326
A Smart Nanomedicine Unleashes a Dual Assault of Glucose Starvation and Cuproptosis to Supercharge αPD‐L1 Therapy
Published 2025-01-01“…Such novel nanomedicine is able to induce lung cancer cell cuproptosis and PD‐L1 upregulation significantly via self‐amplified cascade reactions. Meanwhile, with a decent cancer cell membrane coating, CMGCL exhibited great biosafety, tumor‐targeted efficiency and anti‐tumor effects in LLC lung tumor‐bearing mice models. …”
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2327
Novel Design on Knee Exoskeleton with Compliant Actuator for Post-Stroke Rehabilitation
Published 2024-12-01“…The key contributions of this study include the design of a compact SEA with improved torque density, the development of a knee exoskeleton equipped with a cascaded position controller, and a clinical test validating its effectiveness in alleviating spasticity in stroke patients. …”
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2328
Quantitative Proteomic Analysis of Hepatic Tissue of T2DM Rhesus Macaque
Published 2017-01-01“…Pathway analyses indicated that the biological functions of differentially expressed proteins were related to glycolysis/gluconeogenesis, fatty acid metabolism, complements, and coagulation cascades. Expression change in tryptophan metabolism pathway was also found in this study which may be associations with diabetes. …”
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2329
Tumor microbiome: roles in tumor initiation, progression, and therapy
Published 2025-02-01“…We further propose the tumor microbiome may evade immunity and promote angiogenesis to support tumor progression, while uncovering specific microbial influences on each step of the metastatic cascade, such as invasion, circulation, and seeding in secondary sites. …”
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2330
Peroxiredoxin 6 Attenuates Alloxan-Induced Type 1 Diabetes Mellitus in Mice and Cytokine-Induced Cytotoxicity in RIN-m5F Beta Cells
Published 2020-01-01“…Signal transduction studies showed that PRDX6 prevented the activation of NF-κB and c-Jun N-terminal kinase signaling cascades in RIN-m5F β cells cultured with cytokines. …”
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2331
Method for improving voltage sag tolerance of dual power supply PET based on inter-port power coordination
Published 2025-01-01“…Dual power supply cascaded-type power electronic transformers (DPSC-PET) is connected to two power supplies with high operational reliability and flexible operation mode, and it can be widely used in medium and low voltage distribution networks. …”
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2332
Iddah dan ihdad sebagai pendidikan moral di era modern; issue emansipasi dan pemanfaatan media sosial
Published 2023-06-01“…Namun, perlu diketahui bahwa iddah akan berjalan lancar jika suami sudah memenuhi kewajiban nafkah dan hak untuk istri yang ditinggalkan yang diberikan selama menjalankan masa iddah. …”
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2333
Novel Scalable Topologies of High Power Density Quadratic Converters With Low Voltage Stress on Power Diode
Published 2024-01-01“…This article introduces two novel designs of high power density nonisolated quadratic boost converters, which neither uphold the cascaded architecture nor involve coupled inductors in them. …”
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2334
Mathematical model of the 9th version Universal modeling method: features and results of identification
Published 2020-12-01“…Determining the non-incidence inlet in a blade cascade is an important part of calculating the compressor gas-dynamic characteristics. …”
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2335
The Potential Role of Matrix Metalloproteinases 8 and 9 and Myeloperoxidase in Predicting Outcomes of Bacterial Meningitis of Childhood
Published 2019-01-01“…Matrix metalloproteinases (MMPs) and myeloperoxidase (MPO) contribute to the inflammatory cascade in the cerebrospinal fluid (CSF) during bacterial meningitis. …”
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2336
Optimasi Keuntungan Menggunakan Metode Karush- Kuhn-Tucker (Studi Kasus: Mi Aceh Pattimura di Jambi)
Published 2021-06-01“…Masalah pengeluaran yang tidak stabil dan produksi yang tidak optimal mendorong pelaku usaha untuk merumuskan strategi yang tepat agar usaha dapat terus berjalan dengan lancar. Hal tersebut juga terkait dengan adanya keinginan untuk memaksimalkan keuntungan. …”
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2337
Prevalence of Swine Gastrointestinal Parasites in Nyagatare District, Rwanda
Published 2020-01-01“…Overall, the prevalence of swine gastrointestinal parasites was 84.6%, and the predominant species were Strongyle-type helminths representing 70.2%, followed by coccidia (55.8%), Strongyloides ransomi (39.4%), and Ascaris suum (10.6%). Of all parasitized pigs (n=88), 84.1% developed coinfections involving 2, 3, or 4 different parasite species. …”
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2338
Effects of trehalose on bone healing, physical function, and pain in patients with pertrochanteric fractures: a randomized controlled trial protocol
Published 2024-12-01“…Previous research on animal models indicates that trehalose can improve bone fracture healing by inhibiting the inflammatory cascade. We hope that trehalose can accelerate bone fracture healing in humans, alleviate pain, and ultimately enhance the individual’s quality of life. …”
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2339
Historia, poética y doctrina: los himnos nacionales de Paraguay
Published 2018-01-01“…A lo largo de doscientos años la historia de Paraguay ha oscilado alrededor de tres cantos nacionales: el primero, llamado Himno Primitivo, corresponde a la dictadura de Gaspar Rodríguez de Francia (1811-1840), pertenece a Anastasio Rolón y versa, de manera sencilla y en guaraní, sobre la necesidad de protegerse de las naciones invasoras. …”
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2340
Effect of Antrodia camphorata on Inflammatory Arterial Thrombosis-Mediated Platelet Activation: The Pivotal Role of Protein Kinase C
Published 2014-01-01“…In conclusion, Antrodia camphorata may inhibit platelet activation by inhibiting of Ca2+ and PKC cascade and the Akt pathway. Our study suggests that Antrodia camphorata may be a potential therapeutic agent for preventing or treating thromboembolic disorders.…”
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