Genome-wide analysis of Smad and Schnurri transcription factors in C. elegans demonstrates widespread interaction and a function in collagen secretion by Mehul Vora, Jonathan Dietz, Zachary Wing, Karen George, Jun Kelly Liu, Christopher Rongo, Cathy Savage-Dunn

“…In C. elegans, the BMP2/4 ortholog DBL-1 regulates multiple biological functions, including body size, via a canonical receptor-Smad signaling cascade. Here, we identify functional binding sites for SMA-3/Smad and its transcriptional partner SMA-9/Schnurri based on ChIP-seq peaks (identified by modEncode) and expression differences of nearby genes identified from RNA-seq analysis of corresponding mutants. …”
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Modelling the potential clinical and economic impact of universal antenatal hepatitis C (HCV) screening and providing treatment for pregnant women with HCV and their infants in Egy... by Giuseppe Indolfi, Diana M Gibb, Aya Mostafa, Sarah Pett, Yazdan Yazdanpanah, Sylvie Deuffic-Burban, Anthony E Ades, Karen Scott, Ali Judd, Nadia Hachicha-Maalej, Clotilde Lepers, Intira Jeannie Collins, Manal H El Sayed

“…This study assesses the cost-effectiveness of several screening and treatment strategies for pregnant women and infants in Egypt.Design A Markov model was developed to simulate the cascade of care and HCV disease progression among pregnant women and their infants according to different screening and treatment strategies, which included: targeted versus universal antenatal screening; treatment of women in pregnancy or deferred till after breast feeding; treatment of infected children at 3 years vs 12 years. …”
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Functional interaction between receptor tyrosine kinase MET and ETS transcription factors promotes prostate cancer progression by Elisa Carouge, Clémence Burnichon, Martin Figeac, Shéhérazade Sebda, Nathalie Vanpouille, Audrey Vinchent, Marie‐José Truong, Martine Duterque‐Coquillaud, David Tulasne, Anne Chotteau‐Lelièvre

“…ETS gene fusions, in particular, have the ability to induce the migratory and invasive properties of prostate cancer cells, whereas MET receptor, through its signalling cascades, is able to activate transcription factor expression. …”
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O papel das ecoinovações na transição para uma Economia Circular by Wladmir Henriques Motta

“…O presente estudo visa lançar luz a essa discussão por meio de uma revisão de literatura analisando o importante papel da economia circular e suas relações com as ecoinovações…”
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Penerapan metode sabak, sabki dan manzil dalam pembelajaran tahfidz di sekolah menengah pertama by Nanda Nurul Baiti, Syamsu Nahar, Azizah Hanum OK

“…Pelaksanaan tahfidzul Qur'an dengan metode sabak, sabki, manzil dan jadwal setoran dan murojaah yang dibuat serta kegiatan pendudukung lainnya sudah berjalan dengan efektif, sehingga harapannya seluruh Santri mampu menyelesaikan target hafalan yaitu 5 juz dengan baik dan benar serta kuat dan lancar dengan waktu yang telah ditargetkan. Dan menjadikan Al-Qur'an sebagai pedoman hidup dan dapat mengamalkan isi dan kandungannya dengan baik dalam aplikasi kehidupannya. …”
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Trajetórias de carreira: narrativas dos profissionais de recursos humanos by Lucila Moura Ramos, Pedro F. Bendassolli

“…Vários modelos surgiram na tentativa de compreensão desta jornada, como o modelo da carreira narrativa, o qual parte do pressuposto de que, ao narrar, os indivíduos dão sentido à própria trajetória. …”
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La documentación pedagógica como posibilidad de re-encuentro con las infancias en la formación inicial: Polifonía de miradas a tres voces by Gonzalo MALDONADO-RUIZ, Isabel María FERNÁNDEZ GARCÍA, Encarnación SOTO GÓMEZ

“…Desde este lugar, se conjugan para narrar en primera persona, la experiencia vivida a raíz y en relación con la documentación pedagógica. …”
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Ir-6: A Novel Iridium (III) Organometallic Derivative for Inhibition of Human Platelet Activation by Ren-Shi Shyu, Themmila Khamrang, Joen-Rong Sheu, Chih-Wei Hsia, Marappan Velusamy, Chih-Hsuan Hsia, Duen-Suey Chou, Chao-Chien Chang

“…In conclusion, Ir-6 plays a crucial role by inhibiting platelet activation through the inhibition of signaling pathways, such as the PLCγ2–PKC cascade and the subsequent suppression of Akt and MAPK activation, thereby ultimately inhibiting platelet aggregation. …”
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Soluble Epoxide Hydrolase Inhibitor and 14,15-Epoxyeicosatrienoic Acid-Facilitated Long-Term Potentiation through cAMP and CaMKII in the Hippocampus by Han-Fang Wu, Yi-Ju Chen, Su-Zhen Wu, Chi-Wei Lee, I-Tuan Chen, Yi-Chao Lee, Chi-Chen Huang, Chung-Hsi Hsing, Chih-Wei Tang, Hui-Ching Lin

“…These results indicated that EETs increased NMDAR- and FSK-mediated synaptic potentiation via the AC-cAMP-PKA signaling cascade and upregulated the ERKs and CaMKII, resulting in increased phosphorylation of NR2B and GluR1 in the hippocampus.…”
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Pengaruh kinerja lulusan akademi komunitas Toyota Indonesia terhadap produktifitas kerja proses manufaktur di PT. TMMIN by Praditya Alambara, Nur Azizah

“…Akan tetapi, harapan demikian tidak selalu berjalan lancar sehingga peneliti ingin mengetahui lebih lanjut mengenai pengaruh kinerja lulusan Akademi Komunitas Toyota Indonesia terhadap produktifitas kerja proses manufaktur di PT TMMIN. …”
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Studi literatur: peran administrasi sekolah dalam mendukung implementasi kurikulum by Eka Saputra, Sudarwan Danim, Rambat Nur Sasongko, Dian Pujianto, Rendy Wikrama Wardana

“…Administrasi yang kuat dan terorganisir dengan baik akan memastikan bahwa proses pembelajaran berjalan lancar dan sesuai dengan tujuan kurikulum, sehingga menghasilkan lulusan yang berkualitas dan mampu bersaing dalam berbagai bidang.…”
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Correlation of Color Doppler with Multidetector CT Angiography Findings in Carotid Artery Stenosis by Živorad N. Savic, Lazar B. Davidovic, Dragan Ž. Sagic, Milan D. Brajovic, Srdjan S. Popovic

“…The stenosis area was measured at the narrowest point by NASCET criteria for US/CT. Peak systolic velocity (PSV) over 210 cm/sec and end diastolic velocity (EDV) over 110 cm/sec criteria were applied for stenoses with lumen narrowed over 70%, while PSV under 130 cm/sec and EDV under 100 cm/sec criteria were applied for those with lumen narrowed under 70%. …”
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Identification of signaling networks associated with lactate modulation of macrophages and dendritic cells by Rapeepat Sangsuwan, Bhasirie Thuamsang, Noah Pacifici, Phum Tachachartvanich, Devan Murphy, Abhineet Ram, John Albeck, Jamal S. Lewis

“…While lactate mainly altered STAT3, ERK, and p38 MAPK signaling cascades in DCs, the STAT1 and GSK-3β signaling in MΦs were the major pathways significantly impacted by lactate. …”
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Impact of the COVID-19 pandemic on intra-household gender disparities in the Middle East and North Africa region: A scoping review protocol. by Malak Ghezzawi, Sasha Fahme, Salpy Naalbandian, Jocelyn DeJong, WOMENA Study Group

“…Following PRISMA guidelines for Scoping Reviews, a comprehensive search will be conducted in APA PsycINFO, Arab World Research Source: Al Masdar, EconLit, Global Health, MEDLINE, Scopus, and Web of Science Core Collection, in consultation with an information specialist. …”
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Polarization conversion in soft glass fluoride and chalcogenide fibers for mid-infrared applications by Md Moinul Islam Khan, Md Hosne Mobarok Shamim, Jean-Luc Delarosbil, Younes Messaddeq, Frederic Smektala, Martin Rochette

“…Our experiments using a single PC show a polarization extinction ratio (PER) of 20.7 dB in a ZBLAN fiber (FiberLabs) with a coating of urethane acrylic resin. Cascading two PCs enhances the PER to 39.1 dB while reducing the required compressive force and, thus, increasing the fiber lifetime. …”
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Violencia en la comunidad transgénero: desnudando mi alma frente al mundo by Lorena Realivazquez Pérez, Andrea Sofía Rangel Loya, Daenna Gutiérrez Talavera, Erika Yanet Portillo Siqueiros, Gabriel Federico Santiesteban Rodríguez

“…Conclusiones: se encontraron de manera clara y sin mascaras las huellas de dolor a causa de la violencia en todas sus expresiones, física, psicológica y para algunos sexual. …”
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Movements Toward Living Relationally Ethical Assessment Making: Bringing Indigenous Ways of Being, Knowing, and Doing Alongside Narrative Inquiry as Pedagogy by Trudy CARDINAL, M. Shaun MURPHY, Janice HUBER

“…En 2015, tras el repentino fallecimiento de Mary Isabelle Young, Singing Turtle Woman, Anishinabe kwe Elder, erudita, amiga y coinvestigadora, a menudo contamos y volvemos a narrar historias de cómo sus enseñanzas siguen guiándonos. …”
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Effect of Acetyl tributyl citrate on bone metabolism based on network toxicology and molecular docking technology by Xuan Lin, Kun Lin, Yue Lai, Qingping Peng, Miao Xu, Yiting Xu, Jialin Yang, Huan Liu, Jianlin Shen

“…In-depth Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses, conducted within the Metascape database, revealed that the core targets of ATBC’s influence on bone metabolism are predominantly concentrated within vital signaling cascades, including thyroid hormone signaling, FOXO signaling, glucagon signaling, AMPK signaling, insulin signaling, adipocytokine signaling, and Notch signaling pathways. …”
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Recent Advances in the Mechanisms of Postoperative Neurocognitive Dysfunction: A Narrative Review by Tingting Wang, Xin Huang, Shujun Sun, Yafeng Wang, Linlin Han, Tao Zhang, Tianhao Zhang, Xiangdong Chen

“…Among these, neuroinflammation, mediated by pathways such as the NLRP3 inflammasome and blood–brain barrier disruption, emerges as a pivotal driver, triggering cascades that exacerbate neuronal injury. Oxidative stress and mitochondrial dysfunction synergistically amplify these effects, while neurotransmitter imbalances and microvascular alterations, including white matter lesions, contribute to synaptic dysfunction and cognitive decline. …”
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Evidence in Practice of Tissue Healing with Latex Biomembrane: Integrative Review by Suélia de Siqueira Rodrigues Fleury Rosa, Mário Fabrício Fleury Rosa, Marcos Augusto Moutinho Fonseca, Glécia Virgolino da Silva Luz, Carlos Federico Domínguez Avila, Aldira Guimarães Duarte Domínguez, Aldene Guimarães Duarte Dantas, Von Braun Richter

“…Wound healing is a perfectly coordinated cascade of cellular, molecular, and biochemical events which interact in tissue reconstitution. …”
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