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2261
Procesos de Monumentalización en El Castillo, Meta: Memoria e identidad del conflicto armado
Published 2025-01-01“…Estos procesos buscan abordar la violencia que ha marcado la región, utilizando el espacio público para narrar eventos históricos recientes que van desde la colonización hasta la influencia de la Unión Patriótica, abarcando también la militarización y paramilitarización del área, con graves consecuencias como asesinatos, desplazamientos y desapariciones forzadas. …”
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2262
The SIRT5-JIP4 interaction promotes osteoclastogenesis by modulating RANKL-induced signaling transduction
Published 2025-01-01“…Abstract Receptor activator of nuclear factor kappa-B ligand (RANKL) initiates a complex signaling cascade that is crucial for inducing osteoclast differentiation and activation. …”
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2263
Multiscale Adaptively Spatial Feature Fusion Network for Spacecraft Component Recognition
Published 2025-01-01“…Second, the multi-scale adaptively spatial feature fusion module within the Multi-ASFFD cascades four adaptively spatial feature fusion blocks to fuse low-level, middle-level, and high-level features at various scales to enrich the semantic information for different spacecraft components. …”
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2264
Plant Coping with Cold Stress: Molecular and Physiological Adaptive Mechanisms with Future Perspectives
Published 2025-01-01“…This review summarizes the mechanisms of how plants respond to cold stress, covering four main signal transduction pathways, including the abscisic acid (ABA) signal transduction pathway, Ca<sup>2+</sup> signal transduction pathway, ROS signal transduction pathway, and mitogen-activated protein kinase (MAPK/MPK) cascade pathway. Some transcription factors, such as AP2/ERF, MYB, WRKY, NAC, and bZIP, not only act as calmodulin-binding proteins during cold perception but can also play important roles in the downstream chilling-signaling pathway. …”
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2265
Genetic variants on chromosome 19 (rs439401 and rs4420638) are associated with obesity and high blood pressure in the Algerian population
Published 2019-08-01“…We performed this work using a population-based, cross-sectional study of a representative sample of 787 individuals (378 men and 409 women, aged between 30 and 64 years) recruited in the city of Oran, Algeria (the ISOR Study); the subjects were genotyped for four polymorphisms, rs7412, rs429358, rs4420638 and rs439401, located in the APOE gene, using the KASPar technology. rs439401 showed a significant association with hypertension (HBP). …”
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2266
The Effects of Hyperacute Serum on the Elements of the Human Subchondral Bone Marrow Niche
Published 2018-01-01“…Hyperacute serum (HAS), a new serum derivative, has been designed to approximate the natural coagulation cascade with a single-step, additive-free preparation method. …”
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2267
A multi-stage deep learning network toward multi-classification of polyps in colorectal images
Published 2025-04-01“…Drawing inspiration from the sequential procedure of colonoscopy, where endoscopists first locate polyps and then proceed to detailed observations and diagnoses, we developed a novel multi-stage classification network. This network cascades several convolutional neural networks (CNNs) to mimic the gradual increase in diagnostic specificity seen in clinical settings. …”
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2268
Impaired peroxisomal beta-oxidation in microglia triggers oxidative stress and impacts neurons and oligodendrocytes
Published 2025-01-01“…This dysfunction might contribute to the early neurodegenerative events in X-ALD by triggering and sustaining neuroinflammatory cascades. Therapeutic strategies that target microglial activation and secretion profiles could hold promise in managing peroxisomal disorders such as X-ALD.…”
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2269
Revealing enhanced dilution effect of conjugated polymers in partially miscible blends
Published 2025-01-01“…In this work, we propose a cascade analysis by combining multiple fluorescence microscopic techniques and all‐atom molecular dynamics simulations to study the solid‐to‐solid dilution of poly[2‐methoxy‐5‐(2‐ethylhexyloxy)‐1,4‐phenylenevinylene] (MEH‐PPV) in MEH‐PPV/polystyrene (PS) blends and MEH‐PPV/poly(vinylcarbazole) (PVK) blends. …”
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2270
Analysis of Inflammatory Mediator Profiles in Sepsis Patients Reveals That Extracellular Histones Are Strongly Elevated in Nonsurvivors
Published 2021-01-01“…Treatment strategies relying on a “one-fits-all” approach have failed to reduce mortality, suggesting that therapeutic targets differ between patient subgroups and highlighting the need for accurate analysis of the molecular cascades to assess the highly variable host response. …”
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2271
Preoperative White Blood Cell Count and Risk of 30-Day Readmission after Cardiac Surgery
Published 2013-01-01“…Among the primary causes of readmission are infection and disease states susceptible to the inflammatory cascade, such as diabetes, chronic obstructive pulmonary disease, and gastrointestinal complications. …”
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2272
Contradicciones de la Amazonía en el Brasil: Una nueva perspectiva
Published 2021-12-01“…Más que reflexionar, se trata de hacer un llamado hacia una nueva mirada de esta región amazónica, en caso contrario, se puede estar asistiendo a una masacre de pueblos originarios, de conocimientos tradicionales y de recursos genéticos. …”
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2273
Collapsing Pattern Class-IV Lupus Nephritis Presenting as Posterior Reversible Encephalopathy Syndrome and Cardiac Tamponade: A Rare COVID-19 Sequelae
Published 2025-01-01“…Patients infected with Coronavirus Disease-2019 (COVID-19) have an increased risk of acute renal injury as there is a systemic inflammatory cascade due to an acute infection, causing impairment of basic cellular activities in podocytes. …”
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2274
¿Qué es lo contemporáneo en la literatura amazónica peruana?
Published 2024-12-01“…El artículo propone que, con respecto a la literatura producida desde los centros urbanos amazónicos, la novela de Calvo marcó un antes y un después en la manera de narrar y escribir sobre la Amazonía. Para ello, se analiza y desarrolla el concepto de lo contemporáneo, planteado por Agamben, Premat, entre otros. …”
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2275
Reconstruction of Araucaria araucana cone production reveals warming intensifies regionally synchronized masting
Published 2024-12-01“…Masting is a key driver of plant regeneration dynamics and has cascading effects on food webs and carbon and nutrient fluxes through ecosystems. …”
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2276
Pathway Analysis of Metabolic Syndrome Using a Genome-Wide Association Study of Korea Associated Resource (KARE) Cohorts
Published 2014-12-01“…Through pathway analysis, biological pathways, including electron carrier activity, signaling by platelet-derived growth factor (PDGF), the mitogen-activated protein kinase kinase kinase cascade, PDGF binding, peroxisome proliferator-activated receptor (PPAR) signaling, and DNA repair, were associated with MetS. …”
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2277
Artificial Visual System for Stereo-Orientation Recognition Based on Hubel-Wiesel Model
Published 2025-01-01“…A classical explanation for the mechanism of two-dimensional orientation selectivity within the primary visual cortex is based on the Hubel-Wiesel model, a cascading neural connection structure. The local-to-global information aggregation thought within the Hubel-Wiesel model not only contributed to neurophysiology but also inspired the development of computer vision fields. …”
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2278
Tumor mutation burden for predicting immune checkpoint blockade response: the more, the better
Published 2022-01-01“…Additionally, the universal TMB cut-off of 13 mut/Mb might reveal a general requirement to trigger the sequential cascade from somatic mutations to an effective antitumor immunity.…”
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2279
Optimizing Nitrogen Sources in Top Dressing for Wheat: Field Study on Growth, Yield, and Ammonia Volatilization
Published 2024-01-01“…In alkaline calcareous soils, ammonia volatilization is the primary nitrogen (N) loss process, resulting in the reduced N use efficiency of crops. …”
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2280
Textbook outcome in ovarian cancer and its impact on survival: comparative study
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