Phytochemicals Mediated Remediation of Neurotoxicity Induced by Heavy Metals by Vivek Kumar Gupta, Shweta Singh, Anju Agrawal, Nikhat Jamal Siddiqi, Bechan Sharma

“…Heavy metals induced neurotoxicity and impairment in signalling cascade leading to cell death (apoptosis) has been indicated by several workers. …”
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Advancing Coherent Power Grid Partitioning: A Review Embracing Machine and Deep Learning by Mohamed Massaoudi, Maymouna Ez Eddin, Ali Ghrayeb, Haitham Abu-Rub, Shady S. Refaat

“…There is an increased emphasis on immunizing renewable-dominated power systems from large-scale cascading failures and cyberattacks through optimal power grid partitioning (PGP). …”
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Traffic Control of Bacteria-Derived Molecules: A New System of Host-Bacterial Crosstalk by Hiroaki Konishi, Mikihiro Fujiya, Yutaka Kohgo

“…This paper highlights the intestinal trafficking systems of bacteria-derived molecules that affect the bacterial functions and modulate epithelial signaling cascades. The latter mechanism may contribute to the maintenance of intestinal homeostasis by improving the host damage induced by virulence factors and various disease states.…”
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Temps de travail et organisation du travail : une source de stress et de difficultés de conciliation emploi-famille ? by Diane-Gabrielle Tremblay, Elmustapha Najem, Renaud Paquet

“…Few studies have investigated these issues from this angle and it is clear that the presence of children is often more of a determining factor than the fact of being a woman, while women are still clearly more concerned when daycare services or care for the elderly are involved.…”
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On the Use of Tunable Power Splitter for Simultaneous Wireless Information and Power Transfer Receivers by Abdul Quddious, Muhammad Ali Babar Abbasi, Muhammad Haroon Tariq, Marco A. Antoniades, Photos Vryonides, Symeon Nikolaou

“…The SWIPT system that operates at 2.4 GHz consists of a typical patch antenna, cascaded with the tunable PS, and a voltage doubler rectifier. …”
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Reconciling the IPC and Two-Hit Models: Dissecting the Underlying Cellular and Molecular Mechanisms of Two Seemingly Opposing Frameworks by Carlos F. M. Morris, Muhammad Tahir, Samina Arshid, Mariana S. Castro, Wagner Fontes

“…Inflammatory cascades and mechanisms are ubiquitous during host responses to various types of insult. …”
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Spreading Social Influence with both Positive and Negative Opinions in Online Networks by Jing (Selena) He, Meng Han, Shouling Ji, Tianyu Du, Zhao Li

“…First, we prove that, under the independent cascade model considering positive and negative influences, MPINS is APX-hard. …”
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Enhanced Neuroplasticity by the Metabolic Enhancer Piracetam Associated with Improved Mitochondrial Dynamics and Altered Permeability Transition Pore Function by Carola Stockburger, Davide Miano, Thea Pallas, Kristina Friedland, Walter E. Müller

“…The mitochondrial cascade hypothesis of dementia assumes mitochondrial dysfunction leading to reduced energy supply, impaired neuroplasticity, and finally cell death as one major pathomechanism underlying the continuum from brain aging over mild cognitive impairment to initial and advanced late onset Alzheimer’s disease. …”
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Uncovering a novel SERPING1 pathogenic variant: insights into the aggregation of C1-INH in hereditary angioedema by Lingxi Jiang, Chao Dai, Suyang Duan, Tingting Wang, Chunbao Xie, Luhan Zhang, Zimeng Ye, Xiumei Ma, Yi Shi

“…Our observations indicate that this variant leads to an increase in the accumulation of C1-INH within the endoplasmic reticulum (ER), resulting in the upregulation of GRP75 protein expression. This cascade of events resulted in Ca2+ overload, disruption of mitochondrial structure and function, and eventually triggered apoptosis. …”
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Genome resequencing and genome-wide polymorphisms in mosquito vectors Aedes aegypti and Aedes albopictus from south India by Preeti Acharya, Upasana Shyamsunder Singh, Veeramanoharan Rajamannar, Mayilsamy Muniaraj, Binata Nayak, Aparup Das

“…Particular emphasis was given to gene families involved in mosquito digestion, development, and innate immunity, which could be putative candidates for vector control. Serine protease cascades and their inhibitors called serpins, play a central role in these processes. …”
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White Mold: A Global Threat to Crops and Key Strategies for Its Sustainable Management by Md. Motaher Hossain, Farjana Sultana, Md. Tanbir Rubayet, Sabia Khan, Mahabuba Mostafa, Nusrat Jahan Mishu, Md. Abdullah Al Sabbir, Nabela Akter, Ahmad Kabir, Mohammad Golam Mostofa

“…Each stage of infection triggers a cascade of molecular and physiological events that underpin defense responses against <i>S. sclerotiorum</i>. …”
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Integrated Bioinformatics and Experimental Approaches Identified the Role of NPPA in the Proliferation and the Malignant Behavior of Breast Cancer by Aijun Sun, Xiaonan Sheng, Jinhai Tang, Zhenfeng Yu, Jian Zhang

“…Further, we predicted the transcription modulation of NPPA with PROMO and JASPAR. And we further validated the binding of MZF1 to the -318 bp~-452 bp region of the NPPA promoter with chromatin immunoprecipitation and dual luciferase assay. …”
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The Role of Complement System in Septic Shock by Jean Charchaflieh, Jiandong Wei, Georges Labaze, Yunfang Joan Hou, Benjamin Babarsh, Helen Stutz, Haekyung Lee, Samrat Worah, Ming Zhang

“…Basic and clinical studies suggest that activation of complements in the common cascade, for example, complement component 3 (C3) and C5, is involved in the development of septic shock. …”
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Microstructural Features of Freezing and Thawing-Creep Damages for Concrete Mixed with Fly Ash by Bing Li, Lian-ying Zhang, Ming Li, Hai Pu, Chao Ma, Pei-tao Qiu

“…The microfracture morphology of the concrete was found to include five types of brittle fractures—river, step, cascade, hemispherical, and irregular patterns—and two types of ductile fractures—dimple and peak forest patterns. …”
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The Role of Mannose-Binding Lectin in Severe Sepsis and Septic Shock by Gennaro De Pascale, Salvatore Lucio Cutuli, Mariano Alberto Pennisi, Massimo Antonelli

“…Mannose-binding lectin (MBL) is a serum protein that recognizes a wide range of pathogenic microorganisms and activates complement cascade via the antibody-independent pathway. More than 30% of humans harbor mutations in MBL gene (MBL2) resulting in reduced plasmatic levels and activity. …”
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Adaptive identification of critical nodes for fault‐on voltage support in islanded microgrids by Shiran Cao, Lipeng Zhu, Jiayong Li, Wen Huang, Lili He, Wei Zhang, Huimin Zhao, Zhikang Shuai

“…Abstract The shedding of critical distributed energy resources during faults in an islanded microgrid may induce widespread voltage drops, potentially triggering a cascade of reactions leading to the collapse of the entire system. …”
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Peroxisome Proliferator-Activated Receptor γ Induces the Expression of Tissue Factor Pathway Inhibitor-1 (TFPI-1) in Human Macrophages by G. Chinetti-Gbaguidi, C. Copin, B. Derudas, N. Marx, J. Eechkoute, B. Staels

“…Tissue factor (TF) is the initiator of the blood coagulation cascade after interaction with the activated factor VII (FVIIa). …”
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ALKBH5 suppresses gastric cancer tumorigenesis and metastasis by inhibiting the translation of uncapped WRAP53 RNA isoforms in an m6A-dependent manner by Ziqi Zheng, Feizhi Lin, Baiwei Zhao, Guoming Chen, Chengzhi Wei, Xiaojiang Chen, Runcong Nie, Ruopeng Zhang, Zhoukai Zhao, Zhiwei Zhou, Yuanfang Li, Weigang Dai, Yijia Lin, Yongming Chen

“…The lower level of WRAP53 disrupts the interaction between USP6 and RALBP1 protein, promoting RALBP1 degradation and thereby suppressing the PI3K/Akt/mTOR signaling cascade, ultimately attenuating the progression of GC. …”
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Two Small Peptides from <i>Buthus martensii</i> Hydrolysates Exhibit Antitumor Activity Through Inhibition of TNF-α-Mediated Signal Transduction Pathways by Mengshuang Zhu, Shanshan Zhang, Jiyang Tang, Hairong Hou, Lizhen Wang, Houwen Lin, Xuanming Zhang, Meng Jin

“…The peptides AK and GK competitively bound to the receptor to modulate the TNF/TNFR-signaling cascade and alter the tumor microenvironment. EGFR, TP53, MYC, PTEN, and STAT3 were also identified as major functional targets of the peptides. …”
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Microarray Analysis Reveals a Potential Role of lncRNA Expression in 3,4-Benzopyrene/Angiotensin II-Activated Macrophage in Abdominal Aortic Aneurysm by Yingying Zhou, Jiaoni Wang, Yangjing Xue, Aili Fang, Shaoze Wu, Kaiyu Huang, Luyuan Tao, Jie Wang, Yigen Shen, Jinsheng Wang, Lulu Pan, Lei Li, Kangting Ji

“…Thus, lncRNAs may exert a key role in activated macrophages and intervene the core lncRNAs and may inhibit the occurrence of a series of cascade reactions in the macrophages, which may provide potential targets for AAA caused by smoking.…”
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